Table 5.

Statin Dose Intensity and Equivalency Chart*

Statin %LDL-C HMG-CoA Reductase Inhibitor

Intensity Reduction Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin
63
62
61 40 mg
High- ($196)
60
Intensity
59
(lowers
58 80mg
LDL-C ≥
56 20 mg ($9 gen, $236 br)
50%)
54 ($196)
52
50 10 mg
48 ($196) 40mg
46 ($9 gen, $236 br)
44
42 20mg
Moderate- 40 ($9 gen, $236 br)
40 mg
Intensity 38 4 mg
($4 g, $202 br)
(lowers 36 ($81) 80 mg
LDL-C 30% 80mg ($25 g, 173
to < 50%) 34
($4 gen, br)
20 mg
$306 br) 40 mg
2 mg ($4 g, $202 br)
32 ($25gen, 173 80mg
($81)
5 mg br) ($95 gen,
30 ($196) 40mg $300 br)
10mg 10 mg
($4 gen,
28 ($7 gen, $165 br) ($4 g, $116 br) 20mg
$153)
Low- 26 ($17 gen,
20 mg 117 br)
Intensity 24 1 mg 40mg
($4 gen,
(lowers ($81) ($95 gen, 150
22 5 mg $43 br)
LDL-C < br)
($4 g, $82 br)
30%) 20 10 mg 10mg 20mg
($4 gen, ($19 gen, 58 ($95 gen, 150
18
$43 br) br ) br)

Note: The shading reflects doses listed in the ACC/AHA Guideline on Treatment of Blood Cholesterol (2013) as reflecting high-intensity therapy (≥ 50%
reduction in LDL-C, darker shading) and moderate-intensity therapy (30% to 50% reduction in LDL-C, lighter shading).
*In one trial atorvastatin 40 mg was used for down-titration if unable to tolerate 80 mg.

UMHS Lipid Therapy Guideline, May 2014