CLASS

I Na Channel Blockers 1- Quarter Pounder Delight 2- Lettuce, Tomato & Mayo 3- More Fries Please
Class 1A Phase 0**, prolonged Action potential
Procainamide All types; AF, VT Hypotension, Drug-induced Lupus
Quinidine Cinchonism (HA, vertigo, tinnitus) GI upset, inc.
digoxin levels, torsades de pointes
Disopyramide torsades de pointes, antimuscarinic
Class 1 B – Phase 0* Decrease action potential Best anti-arrythmic drug post MI
Lidocaine VT/VF; IV Convulsions, allergy, CNS sedation or excitation
Mexiletine Oral
Tocainide Oral Agranulocytosis
Class 1C – Phase 0*** Contraindicated post MI
Flecainide Refractory VT proarrythmic
Propafenone
Moricizine

Class II - Beta Blocker Phase 4 -> SA node Hypoglycemia, COPD exacerbation, Impotence
Drug Uses Side effects
Propanolol Post MI Prophylaxis, Bronchopasm, AV block
thyrotoxicosis

Class III – K Channel Blocker Phase 3 Thyroid, Liver, Pulmonary SAIDBre
Drug Uses Side effects
Sotalol oral Torsades, bradycardia, asthma
Amniodarone Refractory arryhtmias Thyroid abn, pulmonary fibrosis, optic neuritis
Ibutilide and Dofetilide AF torsades
Bretylium Refractory post-MI VF Arrhythmia, hypotension

Class IV Ca Channel Blockers Phase 4, 0, prolong 3 -> AV node Edema, Constipation
Drug Uses Side effects
Verapamil AF (1st line); IV, oral Hypotension , cardiac depression
Diltiazem oral

Drug Uses Side effects
Adenosine PSVT (1st line); Flushing, hypotension , bronchospasm
short duration (15 s)
Magnesium sulfate Torsade de pointes Muscle weakness

Arrythmias Drug of Choice Alternate
SVT Adenosine Verapamil
V-tach Amniodarone
Atrial Fibrillation Amniodarone Propafenone
Cardiac glycoside-induced Lidocaine Phenytoin