BEVERAGE PROCESSING TECHNOLOGY

Yomeishu
INSTRUCTOR: Prof. Le Van Viet Man
STUDENTS:
Tran Hien 1752195
Nguyen Thi Minh Thu 1752523
Do Thanh Nhan 1852626
Trieu Tran Tu Uyen 1852857
 01
Functional & Medical effect
The effects themself derive from the materials

Activity Potential
Anti-cancer Cardiovascular disease
Anti-diabetes Arthritis
Anti-bacterial Metabolic syndrome (MetS)
Anti-inflammatory
Anti-obesity
Anti-oxidant
 02
Explanation & Evidence
 Activity
Fang and others reported the anticancer effect of trans-
cinnamaldehyde from Cinnamon cortex, finding that trans-
cinnamaldehyde showed potential effects in restraining tumor cell
growth and in enhancing tumor cell apoptosis.

ANTI- Ginsenosides are mostly responsible for the pharmacological effects

CANCER of ginseng, and Rg3 and Rh2 are recognized as major active
anticancer saponins. Anti-carcinogenic effects of ginseng based on its
diverse mechanisms, such as Rh2 inhibited proliferation, induced
apoptosis in cancer cell lines, and sensitized drug-resistance breast
cancer cells to paclitaxel and . Ginsenosides Rg3 and Rh2 inhibited
proliferation of prostate cancer cells by detachment of the cells.*
 Activity
Inhibits tumor growth, promotes cell cycle arrest and apoptosis ability
come from oleanolic acid (OA) and bioactive compounds mainly in
clove.
OA promoted G0/G1 cell cycle arrest, induced apoptosis in a dose-
dependent manner increased protein expression of p21WAF1/Cip1 and
γ-H2AX and downregulated expression of cell cycle-regulated proteins.
ANTI-
CANCER

Figure: Anti-tumor activity of OA on HT-29 tumors

 Activity
Anderson et al. isolated and characterized the polyphenol type-A
polymers from cinnamon and found that these substances act as insulin-
like molecules. Following this characterization, a new compound from
hydroxycinnamic acid derivatives named naphthalenemethyl ester,
ANTI- which has blood glucose-lowering effects, has been identified, further
confirming cinnamon's antidiabetic effects. Several studies have also
DIABETIC revealed that cinnamon extracts lower not only blood glucose but also
cholesterol levels.

Ginseng therapy decreased fasting glucose, lowered body weight, and

increased glucose utilization and insulin regulation in diabetic patients.*
 Activity

EU have been reported to inhibit the growth of bacteria by using

Eucommia ulmoides. Ethanol extracts of EU at the dose rate of 0.1 and
ANTI- 1.0 mg/mL of 95% (v/v) were reported to exhibit some antibacterial
BACTERIAL (against Acinetobacter baumannii and Staphylococcus aureus) and
antifungal (against Aspergillus fumigatus) effects.
 Activity

Saposhnikovia divaricata contains major bioactive constituents,

including chromones such as prim-O-glucosylcimifugin, 4′-O-β-D-
ANTI- glucosyl-5-O-methylvisamminol, cimifugin, and sec-O-glucosylhamaudol,
INFLAM- which are usually obtained from the roots of the plant. Prim-O-
glucosylcimifugin, the chromone with the highest content in the roots of
MATORY SD, showed significant anti-inflammatory effects.
 Activity

Both Eucommia leaf extract (ELE) and Eucommia green leaf powder
(EGLP) markedly suppressed body weight and white adipose tissue
ANTI- (WAT) in female ICR mice fed high-fat diets. The anti-obesity effect of
OBESITY Eucommia green leaf extract (EGLE) has been linked to various
compounds such as geniposidic acid, asperuloside, and chlorogenic acid
which was isolated from the extract.
 Activity
Curcumin has been shown to improve systemic markers of oxidative
stress. There is evidence that it can increase serum activities of
antioxidants such as superoxide dismutase. Curcumin is a lipophilic
compound, which makes it an efficient scavenger of peroxyl radicals,
therefore, like vitamin E, curcumin is also considered as a chain-breaking
ANTI- antioxidant.

OXIDANT Antioxidant compounds from Eucommia plant reduced the level of free
radicals and improved the disease condition caused by oxidative stress.
Phenolics and flavonoids (rutin, chlorogenic acid, ferulic acid, and caffeic
acid) of medicinal herbs contributed significantly to oxidative activities in
EU.
 Potential

One of the active components isolated from Cinnamomi cassia named 2-

methoxycinnamaldehyde decreases the expression of vascular cell
adhesion molecule. A recent study reported the effects of two CARDIO-
compounds, cinnamic aldehyde and cinnamic acid, isolated from
cinnamon against myocardial ischemia , indicating that cinnamon also VASCULAR
has the potential to be used to treat cardiovascular diseases. DISEASE
 Potential
The therapeutic effect of Radix paeoniae rubra on cardiovascular disease
is also very significant. In an acute myocardial infarction (AMI) rat model,
RPR extract plays a positive role in regulating cardiac enzymes, cytokines,
oxidative stress, coagulation, and apoptosis.

CARDIO-
VASCULAR
DISEASE

Figure: The therapeutic effect of Radix paeoniae rubra on

cardiovascular disease.
 Potential

Systematic review and meta-analysis provided scientific evidence that 8–

12 weeks of standardized turmeric extracts (typically 1000 mg/day of
curcumin) treatment can reduce arthritis symptoms (mainly pain and ARTHRITIS
inflammation-related symptoms). Therefore, turmeric extracts and
curcumin can be recommended for alleviating the symptoms of arthritis,
especially osteoarthritis.
 Potential

Which includes insulin resistance, hyperglycemia, hypertension, low

high-density lipoprotein cholesterol (HDL-C), elevated low-density
lipoprotein cholesterol (LDL-C), elevated triglyceride levels, and obesity, METABOLIC
especially visceral obesity. Curcumin has been shown to attenuate
several aspects of MetS by improving insulin sensitivity, suppressing SYNDROME
adipogenesis , and reducing elevated blood pressure, inflammation, and
oxidative stress
(METS)
03
Conclusion
 Yomeishu is a “herbal liquor”,
which is an alcoholic drink in which
“herbs” are immersed. For centuries,
“herbs” has been used for maintaining
good health, prevent diseases and also
providing flavour. In a herbal liqueur, the
medicinal power of alcohol itself is not
ignored. Alcohol has many effects such
as enhancing appetite by supporting
digestion, warming the body by
improving blood circulation/blood flow,
leading to a deep sleep, etc.
 By addition of the extract of herbs
such as cinnamomi cortex, turmeric,
eucommia ulmoides, ginseng, radix
paeoniae, clove,...into alcohol, more
powerful effects compared to that of
alcohol alone are exerted. The liquor
now has ability to prevent cancer
diseases, anti-obesity effects, protect the
cardiovascular and improve neuron
system and many more incredible effects
on health.
04
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