#551endis

Many chemicals may mimic or interfere with the body’s hormones, known as the
endocrine system. Endocrine disruptors are chemicals that can interfere with
endocrine (or hormonal) systems.
Endocrine disruptors interfere with the synthesis, secretion, transport, binding,
action, or elimination of natural hormones in the body. Any system in the body
controlled by hormones can be derailed by hormone disruptors. Specifically,
endocrine disruptors may be associated with the development of learning
disabilities, deformations of the body various cancers and sexual development
problems.
Endocrine disrupting chemicals cause adverse effects in animals. But limited
scientific information exists on potential health problems in humans. Because
people are typically exposed to multiple endocrine disruptors at the same time,
assessing public health effects is difficult.

#90s
The evidence linking adverse effects to endocrine disruptors is more compelling in
the environment than it is in humans. Endocrine distruptors profoundly alter
reproductive physiology of ecosystems and ultimately impact entire populations.
Some endocrine-disrupting chemicals are slow to break-down in the environment. That
characteristic makes them potentially hazardous over long periods of time. Some
well established adverse effects of endocrine disruptors in various wildlife
species include; eggshell-thinning, displayed of characteristics of the opposite
sex and impaired reproductive development. Other adverse changes in wildlife
species that have been suggested, but not proven include; reproductive
abnormalities, immune dysfunction and skeletal deformaties.

#Note_StorageIncompatibility

Note: Depending on other risk factors, compatibility assessment based on the table
above may not be relevant to storage situations, particularly where large volumes
of dangerous goods are stored and handled. Reference should be made to the Safety
Data Sheets for each substance or article and risks assessed accordingly.