 Electrolytes

 Fluid replenishment
-chemotherapy(focus)
-platinum compounds
-trabectadin
-stop the cell manipulation

-
-melanoma treatment via chemotherapy alone
-

-melanoma(1/10 patients)
-

-
-
-

-chimeric-new type, harvest patients wbc and develop specific antigen. Grow t cells and
introduce to patients
-bcg-stimulates immune system
-t-vec-genetic modified, causes the tumor basically to die
-healthy cells have checkpoints
-cancer cells have specific checkpoints
-blocked the binding
-3 checkpoints

-higher the mutation: higher the response

Melanoma-PD 1 expression
BC-her2 positive

-
-alopecia
-n/v
-

-immune system go overdrive

-resp. pneumonitis
-D/C chemotherapy
-introduce dexa
-platinum based chemo=n/v