NAME OF STUDENT: Estephen Howard Kier O.

De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Adverse effect Nursing Responsibilities

Generic Name: To reduce Contraindicated in Causes potent and Maternal – All patients receiving oxytocin IV
oxytocin postpartum patients selective stimulation Central Nervous System (CNS): must be under continuous
bleeding after hypersensitive to of uterine and subarachnoid hemorrhage, observation by trained personnel
expulsion of the drug. mammary gland seizures, coma who have a thorough knowledge of
Brand Name: placenta smooth muscle. Cardiovascular (CV): the drug.
Pitocin Other When vaginal arrhythmias, HTN, PVCs,
indications delivery is not Pharmacokinetics: hypotension, tachycardia. Discontinue oxytocin administration
include: to advised (patient is Gastrointestinal (GI): nausea, immediately if uterine hyperactivity
Therapeutic: induce or diagnosed with the IV Route – vomiting. or fetal distress occurs. Administer
Oxytocic stimulate following: Onset: 1 min Genitourinary (GU): abruptio oxygen to mother.
labor. placenta previa, Peak: Unknown placentae, tetanic uterine
When the vasa previa, Duration: 1 hr. contractions, postpartum Drug is used to induce or reinforce
Pharmacologic patient invasive cervical hemorrhage, uterine rupture, labor only when pelvis is known to
classification: undergoes carcinoma, genital IM Route – impaired uterine blood flow, be adequate, when vaginal delivery
Exogenous incomplete, herpes), presence Onset: 3-5 min pelvic hematoma, increased is indicated, when fetal maturity is
hormones inevitable, or of cephalopelvic Peak: Unknown uterine motility. assured, and when fetal position is
elective disproportion, or Duration: 2-3 hr. Hematologic: afibrinogenemia, favorable. Use drug only in hospital
abortion. when delivery pelvic hematoma. were critical care facilities and
Dosage: 10 – 40 requires Other: Anaphylaxis, death from prescriber are immediately available.
units in 1,000 ml conversion. oxytocin-induced water
of lactated Ringer intoxication, hypersensitivity Monitor fluid intake and output.
solution, or NSS Contraindicated reactions Effects may lead to fluid overload,
IV, at rate needed when delivery Fetal – seizures, and coma from water
to sustain uterine isn’t imminent, in Central Nervous System (CNS): intoxication.
contraction and prematurity, in infant brain damage, seizures. Monitor and record uterine
control uterine patients with Cardiovascular (CV): contractions, HR, BP, intrauterine
atony. abnormal uterine bradycardia, arrhythmias, pressure, fetal HR, and blood loss at
patterns, or in PVCs. least every 15 minutes.
other obstetric EENT: neonatal retinal
Route: emergencies. hemorrhage. Patient Teaching: Explain use and
Intravenous (IV), Hepatic: neonatal jaundice. administration of drug to patient and
Intramuscular Other: low Apgar scores at 5 family, inform patient to promptly
(IM) minutes, death. report adverse reactions.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: To prevent and Hypersensitivity to Increases tone, rate, Frequent: Nausea, Determine baseline serum calcium
methylergonovine treat postpartum methylergonovine. amplitude of contraction of uterine cramping, level, B/P, pulse, assess for any
maleate hemorrhage Hypertension, uterine smooth muscle. vomiting. evidence of bleeding before
caused by uterine pregnancy, administration.
atony or toxemia. Pharmacokinetics: Occasional:
Brand Name: subinvolution Abdominal pain, Monitor uterine tone, bleeding, B/P,
Methergine PO Route – diarrhea, pulse every 15 minutes until stable
Onset: 5-10 min dizziness, (usually about 1-2 hours.). Assess
Peak: Unknown diaphoresis, extremities for color, warmth,
Therapeutic: Duration: 3 hr. tinnitus, movement, and pain.
Oxytocic bradycardia, chest
IV Route – pain. Report chest pain promptly. Provide
Onset: Immediate support with ambulation if dizziness
Pharmacologic Peak: Unknown Rare: Allergic occurs.
classification: Duration: 45 min reaction (rash,
Ergot alkaloids pruritus), Patient Teaching:
IM Route – dyspnea, severe
Onset: 2-5 min or sudden Advocate patient to avoid smoking as
Dosage: 0.2 mg. Peak: Unknown hypertension. this causes increased
May repeat every Duration: 3 hr. vasoconstriction.
two to four hours Severe
as needed. Rapidly absorbed from GI hypertensive Inform patient to report increases
tract after IM reactions may cramping, bleeding, or foul-smelling
administration. Distributed result in CVA, lochia. As well as pale or cold
Route: Oral, rapidly to plasma, serious hands/feet.
Intramuscular extracellular fluid, tissues. arrhythmias,
(IM), Intravenous Metabolized in liver. peripheral
(IV). Primarily excreted in urine. ischemia may
lead to gangrene.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Adverse Nursing Responsibilities
effect

Generic Name: As part of the Cautions: Renal Promotes hepatic Pain, soreness, Monitor PT, international
phytonadione recommended impairment, formation of coagulation swelling at IM normalized ratio (INR) routinely
dietary allowance newborns (esp. factors II, VII, IX, X. injection site, taking in those taking
(RDA) premature): Risk of Essential for normal pruritic erythema anticoagulants.
Brand Name: hemolysis, clotting of blood. Readily (with repeated
Vitamin K1 Hypoprothrombi jaundice, absorbed from GI tract injections), facial Assess skin for ecchymoses or
nemia caused by hyperbilirubinemia (duodenum)after IM, flushing, altered petechiae
vitamin K subcutaneous taste.
Classification: malabsorption, administration. Assess gums for gingival
Vitamin drug therapy, or Metabolized in liver. Newborns (esp. bleeding.
excessive vitamin Excreted in urine; premature infants)
A dosage eliminated by biliary may develop Assess urine for hematuria
Function: system. Onset of action hyperbilirubinemia.
Antihemorrhagic Hypoprothrombi (increased coagulation Assess hematocrit, platelet count,
nemia caused by factors Severe reactions urine, or stool culture for occult
Chemical: Fat- effect of oral that may occur blood.
soluble vitamin anticoagulants. cramp-like pain,
chest pain, Assess for changes in BP, pulse
Dosage – To prevent dyspnea, facial rate.
Parenteral: hemorrhagic flushing, dizziness,
1mg/0.5 mL, 10 disease of rapid/weak pulse, Assess for increase in amount of
mg/mL newborn. rash, diaphoresis, discharge during menses
hypotension
Oral: 100mcg, Hemorrhagic progressing to Assess peripheral pulses
5 mg disease of shock, cardiac
newborn. arrest. Check for excessive bleeding
Route: from minor cuts or scratches.
Intramuscular
(IM), Oral (PO), Inform and encourage patient to
Subcutaneous. report pain in the abdomen/back
or severe headache.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: Active Serious illness or Live BCG vaccine is an Significant: Risk Assess patient for allergic
bacillus Calmette immunization or high fever, attenuated strain of bacillus of bladder reactions (rash, shortness of
Guerin live prevention of malnutrition, Calmette Guerin; used for contracture breath)
tuberculosis progressive active immunization (intravesical),
dermatitis, serious against tuberculosis. It is malaise, fever and Assess client for compromised
Brand Name: Prophylaxis of heart, kidney or also used as an active chills, flu-like immune systems such as those
TICE BCG carcinoma in situ liver disease, immunotherapy for the symptoms. who are infected with
of urinary serious cell- treatment of bladder HIV/AIDS.
bladder mediated immune carcinoma in situ by Cardiovascular
Therapeutic Anti- deficiency. Childe causing a local, chronic (CV): Anemia Assess clients for common side
tuberculosis live Prophylaxis of w/ clinical AIDS inflammatory response effects (redness at administration
attenuated vaccine primary or involving macrophage and Gastrointestinal site, fever, abdominal
recurrent Ta leukocyte infiltration of the (GI): Abdominal discomfort).
and/or T1 bladder. Resulting in the pain, nausea,
Pharmacologic papillary tumors destruction of superficial diarrhea. Ensure proper drug
classification: following tumor cells of the administration.
BCG live vaccine transurethral urothelium Musculoskeletal/
resection Connective tissue Observe for axillary
(MSK/CT): lymphadenitis (inflammation of
Dosage: 0.05 ml Treatment of Arthralgia, the lymph nodes located in the
ID carcinoma in situ arthritis, myalgia. armpits) as a manifestation of
of urinary regional lymphatic reaction.
bladder Renal/urinary:
Route: intradermal Cystitis, dysuria, Monitor for signs and symptoms
pollakiuria, of systemic BCG infection:
hematuria, UTI, fever, chills, severe malaise, or
urinary cough.
incontinence
Inform family members of
Respiratory: potential adverse effects, advise
thoracic and them to report once manifested.
mediastinal
disorders: Instruct good personal hygiene
Pneumonitis. and clean the vaccination site.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: Chronic HBV Contraindicated on An acyclic nucleotide Central Nervous Monitor renal function and adjust
adefovir dipivoxil infection. patients analogue that inhibits HBV System (CNS): dosage if needed to prevent
hypersensitive to reverse transcription via asthenia, increased risk of nephrotoxicity,
the components of viral DNA chain headache. GI: especially in patients with renal
Brand Name: the drug. termination. abdominal pain, dysfunction.
Hepsera diarrhea,
Use cautiously in Pharmacokinetics: dyspepsia, Patient may develop lactic
patients with renal flatulence, acidosis and severe
Therapeutic: dysfunction, in Oral (PO) Route: nausea, vomiting. hepatomegaly with steatosis
Antivirals those receiving Onset: Unknown during treatment. Women, obese
nephrotoxic drugs, Peak: ½ - 4 hr Genitourinary patients, and those taking
and in those with Duration: (GU): renal antiretrovirals are at higher risk.
Pharmacologic known risk factors Unknown failure, renal Monitor hepatic function. Stop
classification: for hepatic disease insufficiency. drug, if needed.
Nucleosides and
nucleotides Use cautiously in Hepatic: hepatic Stopping adefovir may cause
elderly patients failure, severe worsening of hepatitis.
because they're hepatomegaly
Dosage: Tablets: more likely to have with steatosis, Offer patients HIV antibody
10 mg decreased renal and severe acute testing.
cardiac function. exacerbation of
hepatitis. Inform patient that drug may be
Route: Oral (PO) taken without regard for meals.
Metabolic: lactic
acidosis Tell patient to immediately report
weakness, muscle pain, trouble
Skin: Pruritus, breathing, and other side effects
rash. or adverse reactions.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: To terminate Hypersensitivity to carboprost tromethamine The most frequent Monitor frequency, duration, and
carboprost pregnancy carboprost administered adverse reactions force of contractions and uterine
tromethamine between weeks tromethamine intramuscularly stimulates observed are resting tone. Notify health care
13 and 20 of sterile solution in the gravid uterus related to its professional if contractions are
gestation myometrial contractions contractile effect absent.
Brand Name: Acute pelvic like labor contractions at on smooth
Hemabate Refractory inflammatory the end of a full-term muscle. Monitor vital signs throughout
postpartum disease pregnancy. (Causes uterine the course of therapy.
hemorrhage due contractions by directly Vomiting,
Therapeutic: to uterine atony Patients with active stimulating the diarrhea, nausea, Auscultate breath sounds.
Oxytocic cardiac, pulmonary, myometrium.) abdominal pain, Wheezing and sensation of chest
renal, or hepatic cramps, fevers, tightness may indicate
disease Carboprost tromethamine chills, shivering, hypersensitivity reactions.
Pharmacologic also stimulates the smooth and flushing.
classification: muscle of the human Assess for nausea, vomiting, and
Prostaglandins gastrointestinal tract. This Rare: diarrhea. Premedication with
activity may produce the Endometritis, antiemetic and antidiarrheal is
vomiting or diarrhea or retained placental recommended
Dosage:250 both that is common when fragments,
mcg/mL carboprost tromethamine is excessive uterine Monitor amount and type of
used to terminate bleeding vaginal discharge. Notify health
pregnancy and for use care professional if symptoms of
Route: postpartum. Uterine rupture is hemorrhage occur.
Intramuscular life threatening
(IM) IM Route – Explain purpose of vaginal
Onset: Unknown examinations. And instruct
Peak: 16 hr patient to notify health care
Duration: professionals immediately upon
Unknown fever, chills, foul-smelling
vaginal discharge, lower
abdominal pain, or bleeding.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: Treatment of Hypersensitivity to Tranexamic acid Central Nervous Check doctor’s order
tranexamic acid excessive tranexamic acid. competitively inhibits System (CNS):
bleeding activation of plasminogen Dizziness Do skin testing
resulting from Active (via binding to the Kringle
Brand Name: systemic or local intravascular domain). Thereby reducing Eyes, Ears, Nose, Caution patient to avoid products
Cyklokapron, hyperfibrinolysis. clotting. conversion of plasminogen Throat (EENT): containing aspirin or NSAIDs.
Hemostan, to plasmin (fibrinolysin), an Visual
Lysteda Prophylaxis in Acquired defective enzyme that degrades fibrin abnormalities. Advise patient to take medication
patients with color vision. clots, fibrinogen, and other exactly as directed.
coagulopathy plasma proteins, including Cardiovascular:
Therapeutic undergoing Subarachnoid the procoagulant factors V Hypotension, Unusual change in bleeding
antifibrinolytics surgical hemorrhage. and VII. thromboembolism pattern should be reported to the
procedures. , thrombosis physician.
Pharmacologic In layman’s terms, it helps
classification: with bleeding Gastrointestinal Report severe allergic reactions.
Hemostatic agent (GI): Diarrhea,
nausea, vomiting. Store medication at room
temperature, away from moisture
Dosage: 0.5 g / 1 g and heat.

Route:
Intravenous (IV)

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: To prevent Hypersensitivity to Competitively inhibits Frequent: Dry Assess for use of other CNS
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

scopolamine postoperative scopolamine. action of acetylcholine in mouth, depressants, drugs with

nausea and smooth muscle. Secretory drowsiness, anticholinergic action, history
vomiting Narrow angle glands, and CNS. blurred vision. of narrow-angle glaucoma.
Brand Name: glaucoma. Question medical history as
Trans-Derm Scop, To prevent Rare: Dizziness, listed in Precautions.
Buscopan nausea and restlessness,
vomiting from hallucinations, Monitor for dehydration.
motion sickness. confusion, Observe for improvement
Therapeutic: difficulty of symptoms.
Antinausea, urinating, rash.
antiemetic Patient Teaching:

Avoid tasks requiring alertness,

Pharmacologic motor skills until response to
classification: drug is established (may cause
Anticholinergic. drowsiness, disorientation,
confusion).

Dosage: Use only 1 patch at a time; do not

Transdermal cut.
patch: 1.5 mg/ 2.5
cm2 (1 mg/ 72 hrs) Wash hands after administration.

Route:
Transdermal

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Generic Name: Respiratory tract Contraindicated in Inhibits cell-wall synthesis Gastrointestinal Monitor sodium level because each
ampicillin infections patients during bacterial (GI): diarrhea, gram of ampicillin sodium
hypersensitive to multiplication. nausea, injection contains 2.9 mEq of
GI infections or drug or other pseudomembrano sodium.
Brand Name: GU infections penicillin and Pharmacokinetics: us colitis,
Ampi, Omnipen, (excluding in those with abdominal pain, If large doses are given or if
Penglobe, gonorrhea) infections caused Oral (PO) Route: black therapy is prolonged, bacterial, or
Principen by penicillinase- Onset: Unknown hairy tongue, fungal superinfection may occur,
Uncomplicated producing Peak: 2 hr enterocolitis, especially in elderly, debilitated, or
gonorrhea organisms. Duration: 6-8 hr gastritis, glossitis, immunosuppressed patients.
Therapeutic: Intravenous (IV) Route: stomatitis,
Antibiotics Bacterial Onset: Immediate vomiting. Watch for signs and symptoms of
meningitis or Peak: Immediate hypersensitivity, such as
septicemia Duration: Hematologic: erythematous
Pharmacologic Unknown leukopenia, maculopapular rash, urticaria, and
classification: GI infections and Intramuscular (IM) Route: thrombocytopenia anaphylaxis.
Aminopenicillins GU tract Onset: Unknown thrombocytopenic
infections Peak 1 hr purpura, anemia, Use lowest dosage compatible with
(including Duration: eosinophilia, effective treatment in neonates and
Dosage: Capsules: gonorrhea in Unknown hemolytic anemia, infants because of incompletely
250 mg, 500 mg females. agranulocytosis. developed renal function in these
Injection: 125 mg, patients.
250 mg, 500 mg, Respiratory tract Other:
1 g, 2 g infections. hypersensitivity Monitor patients for CDAD, which
reactions, can be fatal and can occur even
Urethritis in overgrowth of more
males due to nonsusceptible than 2 months after therapy ends.
Route: Oral (PO), gonorrhea organisms. Antibiotic may need to be stopped
Intravenous (IV), and
Intramuscular other treatment begun.
(IM)

Drug Indication Contraindication Mechanism of Side Effect/ Adverse effect Nursing Responsibil
Action
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Generic Name: Rheumatic disorders Contraindicated in Not clearly CNS: euphoria, insomnia, psychotic Determine whether patient is s
hydrocortisone patients defined. behavior, pseudotumor cerebri, other corticosteroids.
Collagen diseases hypersensitive to Decreases vertigo, mood swings, headache,
paresthesia, seizures. Most adverse reactions to cort
drugs or its inflammation
CV: HF, HTN, are dose-or-duration-dependen
Brand Name: Dermatologic diseases ingredients, in , mainly by
edema, arrhythmias, thrombophlebitis,
Colocort, those with systemic stabilizing For better results and less toxi
thromboembolism
Cortef, Severe or intractable allergic fungal infections, leukocyte EENT: cataracts, glaucoma.
once-daily dose in morning.
Cortenema states and in those membranes; GI: peptic ulceration, GI irritation, High dose therapy usually isn
receiving suppresses increased appetite, beyond 48 hours.
Severe acute and chronic allergic immunosuppressive immune pancreatitis, nausea, vomiting.
Therapeutic and inflammatory processes doses together with response GU: menstrual irregularities, increased Always adjust to lowest effect
Corticosteroids involving the eye, and its adnexa live-virus vaccines. stimulates urine calcium levels. Monitor patient’s weight, BP,
bone Hematologic: easy bruising
electrolyte levels.
Respiratory diseases Use with caution in marrow; and Metabolic: hypokalemia,
Pharmacologic patients with recent influences hyperglycemia, carbohydrate Monitor patient for cushingoid
intolerance,
classification: Hematologic disorders MI protein, fat, Unless contraindicated, give a
hypercholesterolemia, hypocalcemia.
Glucocorticoids and Musculoskeletal: growth diet that’s high in potassium a
Neoplastic diseases Use cautiously in carbohydrate suppression in children, muscle Give potassium supplements.
patients with metabolism. weakness, osteoporosis, tendon rupture.
Dosage: Enema: Edematous states disease. Drug may mask or worsen inf
Skin: hirsutism, delayed wound
100 mg/ 60 mL healing, acne, skin eruptions, injection- stress may increase.
Tablets: 5 mg, Ulcerative colitis, regional Drugs can cause site Watch for depression or psych
10 mg, 20 mg enteritis hypercorticism or atrophy. episodes, especially during hi
suppression of the Other: anaphylaxis, angioedema, therapy.
Nervous system disorders HPA axis, hypersensitivity reactions,
cushingoid state, susceptibility to Inspect patient’s skin for petec
particularly in
infections, acute adrenal insufficiency
Route: Oral Severe inflammation younger children or after increased stress or abrupt
Diabetic patient may need inc
(PO), patients receiving withdrawal after long-term therapy. insulin; monitor glucose level
Intravenous Endocrine disorders high-dose therapy. abrupt withdrawal: rebound Gradually reduce dosage after
(IV), Withdraw drug inflammation, fatigue, weakness, therapy.
Intramuscular Adjunctive treatment for slowly. arthralgia,
(IM), ulcerative colitis and proctitis fever, dizziness, lethargy, depression,
Be cautious of look-alike-soun
Suppository Kaposi sarcoma has fainting, orthostatic hypotension,
(Rectal) Acute exacerbations of MS been reported.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindication Mechanism of Action Side Effect/ Adverse effect Nursing Responsibilities

Generic Name: Iron deficiency Contraindicated in Exogenous source of Central Nervous System Rare but fatal
iron sucrose anemia in patients with iron that replenishes (CNS): headache, hypersensitivity reactions,
injection patients who are hypersensitivity to depleted body iron asthenia, malaise, characterized by
hemodialysis drug or its stores and is essential dizziness, fever. anaphylactic shock, loss of
dependent. components, for Hb synthesis consciousness, collapse,
Brand Name: evidence of iron Cardiovascular (CV): HF, hypotension, dyspnea,
Venofer Iron deficiency overload, or anemia Pharmacokinetics: hypotension, chest pain, or seizures, may occur, often
anemia in chronic not caused by iron HTN, fluid retention, within 30 minutes of
kidney disease deficiency. Intravenous Route edema. completing infusion.
Therapeutic: Iron patients not on (IV): Have emergency equipment
supplements dialysis Onset: Gastrointestinal (GI): and therapies readily
Unknown Nausea, vomiting, available.
Iron deficiency Peak: diarrhea, abdominal pain,
Pharmacologic anemia in Unknown taste perversion. Mild to moderate
classification: peritoneal Duration: hypersensitivity reactions
Hematinics dialysis- Unknown Metabolic: gout may occur.
dependent hypoglycemia,
chronic kidney Half-life: 6 hours. hyperglycemia Infusing drug may reduce
Dosage: 20 disease patients hypotension risk.
mg/mL of Musculoskeletal: leg
elemental iron in Maintenance cramps, bone and muscle Obtain iron level 48 hours
2.5-mL, 5-mL, treatment in pain, arthralgia, back pain. after use
and 10-mL single pediatric patients
dose vials with Respiratory: dyspnea, Monitor ferritin level,
hemodialysis- wheezing, pneumonia, transferrin saturation, Hb
dependent cough level, and hematocrit.
Route: chronic kidney
Intravenous (IV) disease, Skin: rash, pruritus, Withhold dose in patient with
nondialysis- injection-site reaction. signs and symptoms of iron
dependent overload.
chronic kidney Other: accidental injury,
disease who are pain, sepsis, Instruct patient to report all
receiving hypersensitivity reactions. adverse reactions and notify
erythropoietin. prescriber immediately.
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

Drug Indication Contraindicatio Mechanism of Side Effect/ Adverse effect Nursing Responsibilities
n Action
Many OTC and prescription
Generic Name: Mild pain Contraindicate Thought to Central Nervous System (CNS): products contain paracetamol; be
paracetamol or fever d in patients produce analgesia agitation (IV), anxiety, fatigue, aware when calculating total
(ampule) hypersensitive by inhibiting headache, insomnia, pyrexia. daily dose.
Mild to to the drug. IV prostaglandin and
moderate form is other Cardiovascular (CV): HTN, Be careful not to confuse
Brand Name: pain with contraindicated substances that hypotension, peripheral edema, milligrams to milliliters. Be sure
Naprex, Amadol, adjunctive in patients with sensitize pain periorbital edema, tachycardia. to base dose on weight for
Aeknil opioid severe hepatic receptors. Drug patients weighing less than 50
analgesics; impairment or may relieve fever Gastrointestinal (GI): nausea, kg, ensure that total daily dose
fever severe active through vomiting, abdominal pain, diarrhea, of acetaminophen from all
Therapeutic: liver disease. central action in constipation (IV). sources doesn't
Analgesics the hypothalamic exceed maximum daily limit.
heat-regulating Genitourinary (GU): oliguria (IV).
center. Consider reducing total daily
Pharmacologic Hematologic: hemolytic anemia, dose and increasing dosing
classification: Para Pharmacokinetics: leukopenia, neutropenia, intervals in patients with hepatic
aminophenol pancytopenia, anemia. or renal impairment.
derivatives. Intravenous (IV)
Route: Hepatic: jaundice. Tell parents to consult prescriber
Onset: 5 – before giving drug to children
Dosage: 150 30 mins Metabolic: hypoalbuminemia younger than age 2.
mg/mL Peak: 15 (IV), hypoglycemia, hypokalemia,
mins hypervolemia, hypomagnesemia, Advise parents that drug is only
Duration: hypophosphatemia (IV). for short-term use; urge them to
Route: 4-6 hrs consult prescriber if giving to
Intravenous (IV) Musculoskeletal: muscle spasms, infants for longer than 3 days,
extremity pain (IV). children for longer than 5 days,
or adults for longer than 10 days.
Respiratory: abnormal breath sounds,
dyspnea, hypoxia, Tell patient to consult prescriber
atelectasis, pleural effusion, for fever lasting longer than 3
pulmonary edema, stridor, wheezing days or
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

(IV). recurrent fever.

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: Acute and Contraindicated in Inhibits protein synthesis; Eyes, Ears, Nose, Store ophthalmic drug at room
erythromycin chronic patients usually bacteriostatic, but Throat (EENT): temperature in tightly closed,
(ophthalmic, conjunctivitis, hypersensitive to may be bactericidal in high minor ocular light-resistant container. Topical
topical) other eye drug. concentrations or against irritations, drug may be flammable; keep
infections highly susceptible redness. away from heat and flame.
(ophthalmic Safety and organisms
Brand Name: ointment) effectiveness of Skin: burning, stop drug for significant diarrhea,
Erygel topical drug in Pharmacokinetics: dryness, pruritus, abdominal cramps,
To prevent children haven’t erythema, or passage of blood or mucus.
ophthalmia been established Ophthalmic, topical Route: irritation, oily
Therapeutic: neonatorum Onset: Unknown skin, peeling, Patient Teaching:
Antibiotics caused by Peak: Unknown sensitivity
Neisseria Duration: reactions. Tell patient to clean eye area of
gonorrhoeae or Unknown excessive discharge before
Pharmacologic Chlamydia Other: ophthalmic application.
classification: trachomatis hypersensitivity
Macrolides (ophthalmic reactons. Teach patient how to apply the
ointment) drug and to watch hands before
and after applying ointment.
Dosage:
Tell patient that vision may be
blurred for a few minutes after
Route: Opthalmic, applying ophthalmic ointment.
topical Close eyes for 1 to 2 minutes
after applying drug.

Advise patient to watch for and

report signs and symptoms of
sensitivity.

Tell patient not to share drug and

NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

paraphernalia with family

member and wash hands after
each application.

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: Chronic  Appendicitis, Bisacodyl is a stimulant  Rectal Periodically evaluate patient’s
bisacodyl constipation;  ulceration of laxative. It stimulates the bleeding need for continued use of drug;
suppository preparation for the rectum, muscle in the wall of the  Abdominal bisacodyl usually produces one
childbirth,  blockage of the small intestine and colon to cramping, or two soft formed stools daily.
surgery, or rectal stomach or generate a bowel  diarrhea,
Brand Name: or bowel intestine, movement. It also alters  nausea, Monitor patients receiving
Dulcolax, Fleet examination.  blood coming water and electrolyte levels  vomiting, concomitant anticoagulants.
Bisacodyl, Magic from anus, in the intestines, increasing  vertigo, Indiscriminate use of laxatives
Bullet, Biscolax,  anal fissure. the level of fluids which results in decreased absorption of
 rectal
Bisac-Evac also produce a laxative-like vitamin K.
burning,
It is also effect
 fluid and
contraindicated in Patient Teaching:
electrolyte
Therapeutic: patients with ileus, imbalance.
Laxatives intestinal Advise the client to add high
obstruction, acute fiber foods slowly to regular diet
abdominal to avoid gas and diarrhea.
Pharmacologic conditions Adequate fluid intake includes at
classification: including least 6-8 glasses per day
Diphenylmethane appendicitis, acute
derivatives inflammatory Do not breast feed while taking
bowel diseases, and this drug without consulting
severe abdominal physician.
Dosage: 10 mg pain associated
with nausea and
vomiting. As well
Route: per rectum as severe
(PR) dehydration, and
patients with
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

known
hypersensitivity to
bisacodyl.

Drug Indication Contraindication Mechanism of Action Side Effect/ Nursing Responsibilities

Adverse effect

Generic Name: Ventricular Contraindicated in A class IB Central Nervous Monitor drug level. Therapeutic
lidocaine arrhythmias patients antiarrhythmic that System (CNS): levels are 1.5 to 5 mcg/mL
hydrochloride (IV) caused by MI, hypersensitive to decreases the confusion, tremor,
cardiac amide-type local depolarization, stupor, Monitor patient for toxicity.
manipulation, or anesthetics. automaticity, and restlessness, light- Seizures may be the first sign of
Brand Name: cardiac excitability in the headedness, toxicity, severe reactions are
Xylocaine, glycosides Contraindicated in ventricles during seizures, lethargy, usually preceded by somnolence,
Xylocard those with Adams- diastolic phase by direct somnolence, confusion, tremors, and paresthesia.
Ventricular Stokes syndrome, action on the tissues, anxiety, If signs of toxicity occur, stop drug
arrhythmias; Wolff-Parkinson- especially the Purkinje hallucinations, at once and notify prescriber.
Therapeutic: shock-refractory White syndrome, network nervousness, Continuing could lead to seizures
Antiarrhythmics ventricular and severe degrees paresthesia, and coma. Give oxygen through a
fibrillation; of SA, AV, or Pharmacokinetics: muscle twitching. nasal cannula if not contraindicated.
pulseless intraventricular Cardiovascular Keep oxygen and CPR equipment
Pharmacologic ventricular block in the (CV): available.
classification: tachycardia absence of an IV Route: hypotension,
Amide derivatives artificial Onset: Rapid bradycardia, new Monitor patient’s response,
pacemaker. Peak: Unknown or worsened especially BP and electrolytes,
Duration: 15-20 arrhythmias, BUN, and creatinine levels. Notify
Dosage: Exercise caution mins cardiac arrest. prescribers if abnormalities occur.
Infusion and reduce dosage Eye, Ears, Nose,
(premixed): 2/4/8 for patients with Half-life: 1½ to 2 hours Throat (EENT): If arrhythmias worsen or ECG
mg/mL complete or (may be prolonged in blurred or double changes occur (QRS complex
Injection (for second-degree heart patients with HF or vision, tinnitus. widens, or PR interval substantially
direct IV use): block or sinus hepatic disease). Gastrointestinal prolongs). Stop infusion and notify
5/10/20 mg/mL bradycardia. (GI): vomiting. prescriber.
Injection (for IV Respiratory:
admixtures): respiratory Instruct patient to promptly report
40/100/200 depression and adverse reactions, such as
NAME OF STUDENT: Estephen Howard Kier O. De Jesus SECTION: 215

mg/mL arrest. palpitations, dyspnea, confusion,

Skin: soreness at anxiety, vision changes, dizziness,
Route: injection site. tinnitus, nausea, and vomiting,
Intravenous (IV), Other: because toxicity can occur.
Intraosseous (IO) anaphylaxis, cold