1. AVOID The chemistry of the ELIMINATE processing or process – using toxic, Feeds SUBSTITUTE flammable or Intermediates environmentally Products Avoid hazardous By-products Combine materials. Impurities Processing aids – Heat transfer fluids Refrigerants Recycles Where the material is – Stock tanks In process In transport 2. REDUCE the As above plus: INTENSIFY inventory of Unit operations and Reduce the scale by hazardous equipment making the process materials. Continuous rather than more effective batch Possibility of faster reaction Combine Hazard density Reduce Spread over larger Divide area Sub-divide inventories
3. REDUCE the Keep simple ATTENUATE
potential for Avoid runaways, explosions surprise. and detonations Simplify Moderate the operating Avoid conditions Dilute Continuous rather than Reduce batch process Dynamics – High inertia hazards slow to develop Low inertia deviations quickly corrected 4. SEPARATE Integrity of containment – SEPARATE people from Design strength chemicals. Joints Contain Seals Remove Moving parts Enclose Minimise corrosion and Reinforce wear Operability and layout Remote control Beware vents and drains