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  • MDA Protopic7

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    24 views6 pages

    MDA Protopic7

    Uploaded by

    the hemi

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 6
    irae Ceo a) The current Teena landscape of atopic derm LEO Atopic dermatitis (AD) is one of the most common skin disorders affecting as much as 20% of children and 2-5% of young adults." Requirements in AD management’: © Short-term: Effective control of acute symptoms Long-term: Stabilization, flare prevention, and avoidance of treatment-related side-effects Step-wise treatment of AD based on disease severity?® Senet) a iB , psychological ne eid ee oa ST eae) a c s r G Eres Eo Ge geese) Pes Men Miecy Moderate impact on every day activities, nee 0 Cantal oe Mee coe ey Dene ee ae alld iL. PO aaa Ay Peet) % - softsnsEUNe Ss Scand Se = Legend: SCORAD, scorn oo dra TS, oie coieosurcids TC ca cakineur ni Aptetrom Wotenbury tau Aca Owmato)Yoeroa2018;32487-682 ad Tay YK otal Arn Aca Med Sgro 201646 499-460, The 2014 American Academy of Dermatology (AAD)* recommends Protopic® for AD cases that are: © Recalcitrant to TCS © Onsensitive areas (eg, face, anogenital area, skin folds) © With skin atrophy due to TCS use © Exposed o long-term TCS use Protopic® and mid-potent TCS are of similar anti-inflammatory efficacy; pimecrolimus cream is less efficacious than mid- potency TCS'4 v. i im ren : ie rie Nerd Prey Peer) Ge ead freee) Pacis Por Peru mas Pocus rsd Clobetasol Betamethasone —_Protopic® Hydrocortisone Desonide Hydrocortisone propionate dipropionate butyrate (0.05% cream, gel (0.25%, 0.5%, (0.05% cream, (0.05% cream, foam, eee (0.1% cream, foam, ointment) 1% cream, lotion, foam ointment) cinreny,sotiin) — YIgTaTe | cintmentsoluton) —_Fyocinolone cinment, slur) Diflorasone Halcinonide ——_fenon oinmen” Hydrocortisone acetonide 001% diacetate (o1%¢cream, eee eee aa yslonata ream soon) en) onion : teas%onmen : cotonideooass, (Oz. ‘ream oinment) ‘Mometasone furoate (0.1% cream) "Sate rupedno seven assesin AD resent ene ere ae exams of common seen steno Protopic® is as effective as mid-potent TCS Global improvement rates were comparable at the end of treatment of Protopic® vs. betamethasone valerate 0.12% ointment in adults* oo — : sm i os Moderately ae re LG ceptor Natagava Hing tne 2006 262785-245 Protopic® significantly improves skin thickness as compared to TCS Intermittent long-term treatment for 12 months with Protopic® 0.1% ointment improves. collagen synthesis and skin thickness! a P

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