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To cite this article: Ece A. Mutlu, Ali Keshavarzian & Gökhan M. Mutlu (2006) Hyperalbuminemia
and elevated transaminases associated with high-protein diet, Scandinavian Journal of
Gastroenterology, 41:6, 759-760, DOI: 10.1080/00365520500442625
CASE REPORT
Abstract
While high protein diets are increasing in popularity, there is a lack of data on their potential adverse effects. We describe two
patients on high protein supplements and exercising for physical fitness. Both developed intermittent abdominal pain,
transient elevations in transaminases and hyperalbuminemia without there being any identifiable cause. The symptoms and
abnormalities on the laboratory tests resolved after the high protein intake was discontinued. While the pathogenesis and
importance of these abnormalities need further study, the findings raise concerns regarding the safety of high protein diets
combined with high intensity exercise.
Key Words: Abnormal liver tests, high protein diet, hpyeralbuminemia, protein supplements
Correspondence: Ece A. Mutlu, MD, MBA, Gastroenterology and Nutrition, Rush University Medical College, 1725 W. Harrison, Suite 206, Chicago, IL
60612, USA. Tel: /1 312 5633 880. Fax: /1 312 5633 883. E-mail: Ece_Mutlu@rush.edu
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tion between this diet and metabolic abnorma-
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