REPUBLIC OF THE PHILIPPINES

UNIVERSITY OF NORTHERN PHILIPPINES

TAMAG, VIGAN CITY
2700 ILOCOS SUR

DRUG STUDY
DOSE,
NAME AND FREQUENCY
ADVERSE NURSING
CLASSIFICATION ROUTE, MECHANISM INDICATIONS CONTRAINDICATIONS
EFFECTS RESPONSIBILITY
OF DRUG DURATION OF OF ACTION
ADMINISTRATION

Generic Name: Dosage: Cefuroxime, For the treatment  Contraindicated in CNS: phlebitis,  Assess patient
CEFUROXIME 1 tab 500 mg like the of many patients thrombophlebitis. for signs and
penicillins, is a different types of hypersensitive to symptoms of
Brand Name: Frequency: beta-lactam bacterial drug. GI: diarrhea, infection prior
ZOLTAX BID antibiotic. By infections such  Use cautiously in pseudomenbranous to and
binding to as bronchitis, patients colitis, nausea, throughout
Classification: Route: specific sinusitis, hypersensitive to vomiting. therapy.
Cephalosporins PO penicillin- tonsillitis, ear penicillin because of  Before
Antibiotic binding proteins infections, skin possibility of cross- HEMATOLOGI initiating
(PBPs) located infections, sensitivity with other C: hemolytic therapy,
inside the gonorrhea, and beta-lactam anemia, obtain a
bacterial cell urinary tract antibiotics. thrombocytopenia, history to
wall it inhibits infections.  Use with caution in transient penicillins or
the third and breast-feeding neutropenia, cephalosporin
last stage of women and in eosinophilia. s. Person with
bacterial cell patients with history a negative
wall autolytic of colitis or renal SKIN: history of
enzymes such sufficiency maculopapular and penicillin
as autolysins; it erythematous sensitivity
is possible that rashes, urticaria, may still have
cefuroxime pain, induration, a allergic
interferes with sterile abcesses, response.
an autolysin temperature  Observe
inhibitor. elevation. patient for
 OTHER: signs and
anaphylaxi symptoms of
s, anaphylaxis
hypersensit (rash, pruritus,
ivity laryngeal
reactions, edema,
serum wheezing).
sickness. Discontinue
the drug and
notify
physicial or
other health
care
professional
immediately if
these
symptoms
occur. Keep
thromepineph
rine, an
antihistamine,
and
resuscitation
equipment
close by in the
event of an
anaphylactic
reaction.
 Instruct
patient to
 report signs of
hypersensitivi
ty.

REPUBLIC OF THE PHILIPPINES

UNIVERSITY OF NORTHERN PHILIPPINES
TAMAG, VIGAN CITY
2700 ILOCOS SUR

DRUG STUDY
DOSE,
NAME AND FREQUENCY
ADVERSE NURSING
CLASSIFICATION ROUTE, MECHANISM INDICATIONS CONTRAINDICATIONS
EFFECTS RESPONSIBILITY
OF DRUG DURATION OF OF ACTION
ADMINISTRATION
Generic Name: Dosage: Ceftriaxone Ceftriaxone is  Contraindicated in GI:  Before giving
CEFTRIAXONE 1 tab 500 mg works by used for the patients with pseudomembranou the drug, ask
SODIUM inhibiting the treatment of the hypersensitivity to s colitis, diarrhea. the patient if
Frequency: mucopeptide infections drug or other he/she has
Brand Name: BID synthesis in the (respiratory, cephalosporin. Hematologic: allergy to
ROCEPHINE bacterial cell skin, soft tissue,  Use cautiously in eosinophilia, penicillin or
Route: wall. The beta- UTI, ENT) patients thrombocytosis, cephalosporin.
Classification: PO lactam moiety caused by hypersensitivity to leukopenia.  Assess patient
Antibiotic of ceftriaxone susceptible penicillin because of for signs and
binds to organisms.  possibility of cross- Skin: symptoms of
carboxypeptidas sensitivity with other Pain, induration, infection prior
es, Organisms that beta-lactam tenderness at to and
endopeptidases, are generally antibiotics. injection site, rash. throughout
and susceptible to  Use with caution in therapy.
transpeptidases ceftriaxone breast-feeding Other:  Before
in the bacterial include S. women and in Hypersensitivity initiating
cytoplasmic pneumoniae, S. patients with history reactions, serum therapy,
membrane. pyogenes (group of colitis or renal sickness, obtain a
These enzymes A beta-hemolytic sufficiency anaphylaxis. history to
are involved in streptococci), penicillins or
cell-wall coagulase- cephalosporin
synthesis and negative s. Person w
cell division. staphylococci,
Binding of Some
ceftriaxone to Enterobacter
these enzymes spp, H.
causes the influenzae, N.
enzyme to lose gonorrhoeae, P.
activity, mirabilis, E. coli,
therefore, the Klebsiella spp,
bacteria M. catarrhalis, B.
produce burgdorferi, and
defective cell some oral
walls, causing anaerobes.
cell death.