Know Your COVID19 Vaccine

1. COVAXIN -The indigenous vaccine developed by Bharat Biotech

Covaxin is one of the vaccines approved under Emergency use to combat Covid-19. While the media
and government have been spreading all the promises related to it, it is important to understand what
does this vaccine contain and what processes have been used to make it.
Below is the Data-Sheet providing details of Covaxin:
I would like to focus your attention towards the red box which contains the ingredients of Covaxin.
We will now take each of the ingredients and have a look at them:

a. TLR 7/8 agonist (imidazoquinolinone)

TLR 7/8 agonist is used as vaccine adjuvant in the vaccine. An adjuvant is a drug or other
substance, or a combination of substances, that is used to increase the efficacy or potency of
certain drugs.
Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene.[5] TLR8 has also
been designated as CD288 (cluster of differentiation 288). TLR8 is an endosomal receptor that
recognizes single stranded RNA (ssRNA), and can recognize ssRNA viruses such as
Influenza, Sendai, and Coxsackie B viruses. TLR8 binding to the viral RNA recruits MyD88
and leads to activation of the transcription factor NF-κB and an antiviral response.

The formulation of TLR 8 is Phosphate-buffered solution, pH 7.2, containing 0.09% sodium

azide and 0.2% (w/v) BSA (origin USA). Interestingly BSA stands for bovine serum albumin
and is derived from bovine (Cow or ox) blood by a proprietary heat shock treatment. The plasma
used for the process is collected as a byproduct of the meat industry.

Source: https://www.biolegend.com/en-us/products/pe-anti-human-cd288-tlr8-antibody-17334

Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by

the TLR7 gene. TLR7 recognizes single-stranded RNA in endosomes, which is a common
feature of viral genomes which are internalised by macrophages and dendritic cells. TLR7
recognizes single-stranded RNA of viruses such as HIV and HCV. Due to their ability to induce
robust production of anti-cancer cytokines such as interleukin-12, TLR7 agonists have been
investigated for cancer immunotherapy. The formulation of TLR 8 is Phosphate-buffered
solution, pH 7.2, containing 0.09% sodium azide.
Source: https://www.biolegend.com/en-us/products/pe-anti-mouse-cd287-tlr7-antibody-19413
Addition: While checking this article caught eye, for doctors and learned persons.
(https://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.3000398) Activation
of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a
novel simple technology for sexing sperm

Interestingly both TLR 7 and TLR 8 contains 0.09% Sodium Azide which according to Wikipedia :
Sodium azide has caused deaths for decades.[16] It is a severe poison. It possesses the NFPA
704's highest rating of 4 on the health scale. It may be fatal in contact with skin or if
swallowed.[17] Even minute amounts can cause symptoms. The toxicity of this compound is
comparable to that of soluble alkali cyanides. And it is used in in agriculture for pest control of
soil-borne pathogens.
Source: https://en.wikipedia.org/wiki/Sodium_azide

Continued in the next page….

b. Aluminum Hydroxide gel:

Aluminum has been , across last 15-20 years, linked to neurological disorder within humans and
animals. Aluminum Adjuvant has also been seen as to play an important role in Gulf War Illness
among veterans in 1991.
Source: https://pubmed.ncbi.nlm.nih.gov/17114826/
https://pubmed.ncbi.nlm.nih.gov/19740540/
https://pubmed.ncbi.nlm.nih.gov/23609067/

c. Whole viron inactivate SARS CoV-2 antigen

The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-
known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum
hydroxide gel (Algel) or a novel TLR7/8 agonist adsorbed gel.
While we have deciphered the Algel and TLR7/8 agonist above, lets proceed to vero cell
platform (CCL-81). Vero-cells are used as host cells for growing viruses.
Vero cells are a lineage of cells used in cell cultures.[1] The 'Vero' lineage was isolated
from kidney epithelial cells extracted from an African green monkey
Source: https://newdrugapprovals.org/2021/03/17/covaxin-bbv-152/
https://en.wikipedia.org/wiki/Vero_cell

d. 2-Phenoxyethanol
As per Wikipedia, Phenoxyethanol is a vaccine preservative and potential allergen, which may
result in a nodular reaction at the site of injection.[8] It reversibly inhibits NMDAR-mediated ion
currents.[9] Ingestion may cause central nervous system and respiratory depression, vomiting
and diarrhea in infants, particularly when combined with chlorphenesin.
Phenoxyethanol is used as a perfume fixative; an insect repellent; an antiseptic;
a solvent for cellulose acetate, dyes, inks, and resins; a preservative for pharmaceuticals,
cosmetics and lubricants; an anesthetic in fish aquaculture; and in organic synthesis.
Phenoxyethanol is an alternative to formaldehyde-releasing preservatives.[4] In Japan and the
European Union, its concentration in cosmetics is restricted to 1%. Studies have shown that
phenoxyethanol has the potential to cause negative effects to the brain and nervous system.
These dangers can occur through inhalation or absorption of phenoxyethanol
Source: https://en.wikipedia.org/wiki/Phenoxyethanol
https://pubmed.ncbi.nlm.nih.gov/31588615/
https://phenoxyethanol.weebly.com/the-chemical.html