ATLAS OF HUROPATH

CelltraZone Co., Ltd. │ www.celltrazone.com

02 Normal
04 Squamous cell carcinoma
08 Small cell carcinoma
09 Adenocarcinoma
14 Metastatic adenocarcinoma

SPUTUM
SPUTUM

Normal
Bronchial washing (M-59 years)
[Cytologic Criteria]
Scattered macrophages and some lymphocytes
Normal chromatic nuclei with smooth nuclear border
Multinucleated giant cells with nuclei similar to
macrophages
Giant cells with nuclei similar to those of macrophages

2 CelltraZone Co., Ltd.

SPUTUM

Normal
Bronchial washing (M-32 years)
[Cytologic Criteria]
Scattered macrophages with tingible bodies in their
cytoplasm
Normal chromatic nuclei with smooth nuclear border
Occasionally small nucleoli

3 CelltraZone Co., Ltd.

SPUTUM

Squamous cell carcinoma

Sputum (F-69 years) [Cytologic Criteria]
Singly scattered atypical cells
Markedly enlarged squamous cells with dense
orangeophilic cytoplasm
Bizarre nuclei with marked hyperchromasia
Irregular nuclei with coarse chromatin

4 CelltraZone Co., Ltd.

SPUTUM

Squamous cell carcinoma

Sputum (M-76 years)
[Cytologic Criteria]
Markedly enlarged squamous cells with orangeophilic
cytoplasm
Bizarre nuclei with irregular coarse chromatin

5 CelltraZone Co., Ltd.

SPUTUM

Squamous cell carcinoma

Sputum (M-75 years)
[Cytologic Criteria]
Markedly enlarged squamous cells with dense
orangeophilic cytoplasm
Bizarre nuclei with coarse chromatin

6 CelltraZone Co., Ltd.

SPUTUM

Squamous cell carcinoma

Bronchial washing (M-79 years)
[Cytologic Criteria]
Markedly enlarged squamous cells with dense
orangeophilic cytoplasm
Bizarre nuclei with coarse chromatin
Giant cells with sharp point nuclei

7 CelltraZone Co., Ltd.

SPUTUM

Small cell carcinoma

Bronchial washing (M-76 years)
[Cytologic Criteria]
Loose cell clusters with scanty cytoplasm
(high N/C ration)
Hyperchromatic nuclei with salt-and-pepper chromatin
pattern
Nuclear molding

8 CelltraZone Co., Ltd.

SPUTUM

Adenocarcinoma
Bronchial washing (F-45 years)
[Cytologic Criteria]
Formation of cell balls or loose cluster
Enlarged nuclei with conspicuous nucleoli
Abundant cytoplasm with intracytoplasmic vacuoles in
some cells

9 CelltraZone Co., Ltd.

SPUTUM

Adenocarcinoma
Bronchial washing (F-45 years)
[Cytologic Criteria]
Formation of cell balls or loose clusters
Enlarged nuclei with conspicuous nucleoli
Abundant cytoplasm with intracytoplasmic vacuoles in
some cells

10 CelltraZone Co., Ltd.

SPUTUM

Adenocarcinoma
Bronchial washing (F-77 years)
[Cytologic Criteria]
Formation of loose clusters
Enlarged nuclei with high nuclear to cytoplasmic ratio
Some conspicuous nucleoli with coarse chromatin

11 CelltraZone Co., Ltd.

SPUTUM

Adenocarcinoma
Bronchial washing (F-77 years)
[Cytologic Criteria]
Formation of loose clusters
Enlarged nuclei with high nuclear to cytoplasmic ratio
Some conspicuous nucleoli with coarse chromatin

12 CelltraZone Co., Ltd.

SPUTUM

Adenocarcinoma
Bronchial washing (M-66 years)

[Cytologic Criteria]
Clustered cells with enlarged nuclei
Coarse chromatin with macro-nucleoli

13 CelltraZone Co., Ltd.

SPUTUM

Metastatic adenocarcinoma
Bronchial washing (F-83 years)
[Cytologic Criteria]
Formation of loose clusters
Variably enlarged nuclei with coarse chromatin and large
nucleoli
Fuzzy cytoplasm with intracellular mucin-like material

14 CelltraZone Co., Ltd.

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