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Journal of the Formosan Medical Association (2020) 119, 1093e1100

Available online at www.sciencedirect.com

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journal homepage: www.jfma-online.com

Original Article

Bidirectional relationships of psychiatric


symptoms with internet addiction in college
students: A prospective study
Yen-Ju Lin a,b, Ray C. Hsiao c,d, Tai-Ling Liu a,**,
Cheng-Fang Yen a,*

a
Department of Psychiatry, Kaohsiung Medical University Hospital, and School of Medicine and
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
b
Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai’s Home, Kaohsiung, Taiwan
c
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine,
Seattle, WA, USA
d
Department of Psychiatry, Children’s Hospital and Regional Medical Center, Seattle, WA, USA

Received 4 January 2019; received in revised form 4 May 2019; accepted 5 October 2019

KEYWORDS Background/Purpose: This prospective study evaluated the predictive ability of psychiatric
Internet addiction; symptoms at initial consultation for the occurrence and remission of Internet addiction during
Psychiatric a 1-year follow-up period among college students. Furthermore, it evaluated the predictive
symptoms; ability of changes in psychiatric symptoms for Internet addiction at the initial consultation dur-
College student ing the 1-year follow-up period among college students.
Methods: Five hundred college students (262 women and 238 men) were recruited. The base-
line and follow-up consultations measured the levels of Internet addiction and psychiatric
symptoms using the Chen Internet Addiction Scale and Symptom Checklist-90 Revised,
respectively.
Results: The results indicated that severe interpersonal sensitivity and paranoia symptoms
might predict the incidence of Internet addiction at 1-year follow-up. The college students
with internet addiction did not have significant improvement in the severities of psychopathol-
ogy, whereas those without internet addiction had significant improvement in obsession-
compulsion, interpersonal sensitivity, paranoid and psychoticism during the same period.
Conclusion: Psychiatric symptoms and Internet addiction exhibited bidirectional relationships
in college students during the 1-year follow-up period.

* Corresponding author. Department of Psychiatry, Kaohsiung Medical University Hospital, 100 Tzyou 1st Rd, Kaohsiung, Taiwan. Fax: þ886
7 3134761.
** Corresponding author. Department of Psychiatry, Kaohsiung Medical University Hospital, 100 Tzyou 1st Rd, Kaohsiung, Taiwan. Fax: þ886
7 3134761.
E-mail addresses: dai32155@gmail.com (T.-L. Liu), chfaye@cc.kmu.edu.tw (C.-F. Yen).

https://doi.org/10.1016/j.jfma.2019.10.006
0929-6646/Copyright ª 2019, Formosan Medical Association. Published by Elsevier Taiwan LLC. This is an open access article under the CC
BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
1094 Y.-J. Lin et al.

Copyright ª 2019, Formosan Medical Association. Published by Elsevier Taiwan LLC. This is an
open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-
nc-nd/4.0/).

Introduction proposed that obsessive self-focused rumination might


cause repetitive use of the Internet.27 Reicher proposed the
Global rates of Internet use have increased rapidly because deindividuated effect in the Internet which might lower the
the Internet has become an essential tool for communica- threshold for exhibiting socially inhibited behaviors and
tion, education, and socializing.1 However, Internet further contributed to aggressive behaviors.28 Individuals
addiction has become a global mental health problem.2 The with avoidance coping style was positively correlated with
association between Internet addiction and psychiatric Internet addiction,29 while higher levels of emotional and
symptoms was investigated abundantly in the 2010s. Re- avoidant coping were associated with higher levels of
searchers have suggested that Internet addiction leads to paranoia.30 However, most of previous studies have exam-
difficulty in maintaining real-life interpersonal relation- ined the relationship between Internet addiction and the
ships, impairs everyday activities, worsens academic work, sole dimension of psychiatric symptoms. The review study
and hinders occupational functioning.3e5 determined that multiple dimensions of psychiatric symp-
A meta-analysis of 31 countries revealed a global prev- toms related to Internet addiction.31 Further study using
alence of 2.6%e10.9% of Internet addiction for all-age the scales such as the Symptom Checklist-90-Revised that
users.6 The estimate of incidence rates of Internet addic- measure multiple dimensions of psychiatric symptoms may
tion varied in different age cohorts. Ko et al. proposed an provide knowledge to the relationship between Internet
incidence rate of 7.5% in young adolescents during the 1- addiction and psychopathology. Moreover, the cross-
year period from Grade 7 to Grade 8,7 while incidence sectional design of the previous studies limited the possi-
ranging between 2.5 and 3.6% over the 2-year period in bility of determining the temporal relationship between
junior high school students was reported.8 Previous studies Internet addiction and psychiatric symptoms.
revealed that adolescents are especially prone to develop Prospective studies examining the relationship between
Internet addiction.9 Cross-cultural epidemiological studies Internet addiction and psychiatric symptoms are relatively
on Internet addiction have reported a remarkably higher scant. A 2-year prospective study determined that
prevalence rates among adolescents in Asian compared to emotional problems, depression, and social phobia at
those among adolescents in Western countries.9 Estimated baseline are predictive of Internet addiction.32 A 9-month
15.3%e17.9% of college students in Taiwan are addicted to prospective study reported that Internet addiction at
the Internet.10,11 One of possible etiologies accounting for baseline is predictive of depression.33 A 2-year longitudinal
the various incidence and prevalence of Internet addiction study found that both pathological Internet use symptoms
among previous studies is the miscellaneous diagnostic in- and emotional problems may contribute to the vicious cycle
struments assessing Internet addiction based on different that supports the perpetuation of pathological Internet
conceptual framework. Young et al. proposed Internet use.34
Addiction Diagnostic Questionnaire (IADQ) and Internet Studies on the temporal bidirectionality of the rela-
Addiction Test (IAT) as self-reported screening instruments tionship between Internet addiction and psychiatric symp-
to measure the extent of involvement with the computer toms are scant. To our knowledge, only one study examined
and Internet addictive behavior.12,13 Generalized prob- the temporal bidirectionality of the relationship between
lematic Internet use scale (PIU) was developed to assess Internet addiction and psychiatric symptoms. Dong and
Internet-related cognitions and social functions.14 The colleagues (2011) reported that depression, anxiety, and
Chen Internet Addiction Scale (CIAS) was validated in hostility on the Symptom Checklist-90-Revised (SCL-90-R)
assessing the core symptoms of Internet addiction, as well were the sequela but not the precursors of Internet
as Internet-related social and physical problems.15 addiction in a 1-year longitudinal study; however, Internet
A variety of psychiatric symptoms have been proposed to addiction in that study was diagnosed through retrospective
be associated with Internet addiction. Cross-sectional assessment. Prospective studies on the bidirectional inter-
studies have reported significant associations of Internet action between Internet addiction and psychiatric symp-
addiction with depressive symptoms, anxiety, toms in the same study group may provide further evidence
obsessiveecompulsive symptoms, inattention, hyperactivi- for the reciprocal relationships between Internet addiction
ty, and aggressive behaviors.16e21 Several cross-sectional and multidimensional psychiatric symptoms and serve as
studies have also discovered positive correlations be- the basis for prevention programs.
tween Internet addiction and the characteristic traits of This study evaluated the prediction of psychiatric
psychoticism, paranoid, and interpersonal sensitivity.22e25 symptoms at the initial consultations for the occurrence
Lee et al. reported that the homozygous short alleles of and remission of Internet addiction during a 1-year follow-
the serotonin transporter gene promoter region may up period among college students. Furthermore, it evalu-
partially account for the association between excessive ated the prediction of changes in psychiatric symptoms for
Internet users and depressive disorder.26 Pratarelli Internet addiction at the initial consultation during the 1-
Psychiatric symptoms and Internet addiction 1095

year follow-up period among college students. We hy- Internet addicts, were stratified into group III or IV based on
pothesize that psychiatric symptoms at baseline predict the remission or continuation of the behavior, respectively. A
occurrence and nonremission of Internet addiction 1 year chi-square and a t tests was used to evaluate the difference
later and that Internet addiction predicts exacerbation of in gender and age between groups I and II and between
psychiatric symptoms 1 year later. groups III and IV, respectively. A p < .05 was considered
significant for these two tests. The relationships between
the incidence of Internet addiction and psychiatric symp-
Methods toms at the initial consultation for the members of groups I
and II were investigated by Mann-Whitney U test. The re-
Participants lationships between the remission of Internet addiction and
psychiatric symptoms at the initial consultation for the
Through advertising, 500 college students between 20 and members of groups III and IV were also investigated by
30 years old (262 women and 238 men) were recruited and Mann-Whitney U tests. Because of multiple comparison of
participated in this study. Their mean age was 22.1 years nine dimensions of psychopathology on the SCL-90R, a
(standard deviation [SD]: 1.8 years). Informed consent was p < .006 (.05/9) was considered significant for Mann-
obtained from all participants prior to assessment. The Whitney U tests.
study was approved by the Institutional Review Board of Additionally, we aspired to evaluate whether changes in
Kaohsiung Medical University Hospital. psychiatric symptoms during the 1-year period differed
between college students with and without Internet
Measures addiction at the initial consultation. A Wilcoxon signed
ranks test was used to evaluate the change in psychiatric
symptoms on the SCL-90-R between the initial and follow-
Chen Internet Addiction Scale
up consultation for all participants in the Internet addiction
We used the self-administrated Chen Internet Addiction
and nonaddiction groups based on their classification in the
Scale (CIAS) to assess the severity of participants’ Internet
initial consultation. A p < .006 was considered significant
addiction in the month preceding the study.15 The CIAS
for Wilcoxon signed ranks tests. All statistical analyses
contains 26 items rated using a four-point Likert scale with
were performed using SPSS 20.0 (SPSS Inc., Chicago, IL,
scale scores ranging from 26 to 104.15 High scores indicate
USA).
severe Internet addiction. The internal reliability (Cron-
bach’s a) of the CIAS in the present study was .93. A 67e68
cut-off point on the CIAS has the highest diagnostic accu- Results
racy and acceptable sensitivity and specificity.35 Accord-
ingly, those with CIAS scores of 68 were assigned to the
A total of 324 college students (65.8%, 169 women and 155
Internet addiction group.
men) underwent follow-up assessment 1 year later. Of 176
participants who did not receive the follow-up assessment,
Symptom Checklist-90-Revised
96 (54.5%) were disconnected, 48 (27.3%) refused partici-
The SCL-90-R is a self-report scale designed to measure the
pating in the follow-up assessment, and 32 (18.2%) had
general psychopathology associated with the constructs of
motivation but were not able to participate in the follow-up
somatization, obsessionecompulsion, interpersonal sensi-
assessment due to work or army service. No difference in
tivity, depression, anxiety, hostility, phobic anxiety, para-
gender was found between participants who received and
noid ideation, psychoticism, and sleep and appetite
did not receive the follow-up assessment (p Z .884),
problems.36 The SCL-90-R consists of 90 symptom state-
whereas participants who received the follow-up assess-
ments that participants use to rate severity on the basis of
ment were older than those who did not receive the follow-
their experiences during the preceding week. Each item is
up assessment (p Z .047). No difference in the proportion
rated on a five-point scale of distress (0e4), ranging from
of internet addiction was found between participants who
“not at all” to “extremely.” High scores on the SCL-90-R
received and did not receive the follow-up assessment
indicate that participants have severe psychiatric symp-
(p Z .819).
toms. The validity of the Chinese-language version of the
Of the 268 participants in groups I and II who had no
SCL-90-R for assessing the neurotic symptomatology of pa-
Internet addiction at the initial consultation, 20 (7.5%)
tients in Taiwan was established.37
were deemed to have Internet addiction at the follow-up
consultation (group II). Of the 56 individuals in groups III
Study process and statistical analysis and IV who had Internet addiction at the initial consulta-
tion, 26 (46.4%) were classified as free of Internet addiction
During the initial assessment, all participants were invited at the follow-up consultation (group III).
to complete the CIAS and SCL-90-R. The participants were Comparisons of the demographic characteristics and
invited to again complete the CIAS and SCL-90-R 1 year SCL-90-R psychiatric symptoms between groups I and II are
later. Depending on the initial and follow-up CIAS scores, presented in Table 1. The results reveal that compared with
the participants were assigned to one of four groups group I, group II had more severe interpersonal sensitivity
(Fig. 1). Participants deemed nonaddicted in the initial and paranoia on the SCL-90-R at the initial assessment,
assessment were stratified into group I or II on the basis of indicating that severe interpersonal sensitivity and para-
subsequent nonaddiction or addiction status, respectively. noia symptoms on these SCL-90-R subscales might predict
The remaining participants, who were initially deemed the incidence of Internet addiction at 1-year follow-up.
1096 Y.-J. Lin et al.

All participants

Initial assessment

Non addiction Internet addiction

Follow-up assessment

Non addiction Internet addiction Non addiction Internet addiction

Group I (n = 248) Group II (n = 20) Group III (n = 26) Group IV (n = 30)

Figure 1 Participants were assigned to one of four addiction groups. The participants deemed nonaddicted at baseline
assessment were stratified into groups I and II based on the follow-up evaluation as nonaddicted or addicted, respectively. The
participants deemed addicted initially but who had remitted on follow-up were assigned to group III, whereas those who remained
addicted were assigned to group IV.

Comparisons of the demographic characteristics and predicted the development of Internet addiction in the 1-
SCL-90-R psychiatric symptoms between groups III and IV year follow-up period. College students with high interper-
are presented in Table 1. The participants in group III were sonal sensitivity exhibited low self-esteem, high sensitivity
younger than those in group IV. However, no dimension of to criticism, reliance on others, and high insecurity in inter-
psychiatric symptoms was significantly associated with personal relationships.38 Moreover, problematic Internet
Internet addiction remission. users exhibited higher interpersonal sensitivity, asocial
The results of SCL-90-R score comparison between the behavior, unassertiveness, criticism, and distrust than those
initial and follow-up consultations among the participants without Internet problems.38 College students with high
with and without Internet addiction at the initial consul- interpersonal sensitivity have feelings of inadequacy, infe-
tation are shown in Table 2. The results of Wilcoxon signed riority and self-doubt.39 They obtained more support and
ranks test revealed that the severities of obsession- self-confidence from the Internet rather than face-to-face
compulsion, interpersonal sensitivity, paranoid and psy- interaction and may indulge in the virtual world and isolate
choticism in the nonaddiction group significantly decreased themselves from the outside environment.38 Previous studies
from the initial and follow-up consultations, whereas the showed that individuals with Internet addiction have more
severities of all dimensions of psychopathology in the often personality disorders than those without.40
internet addiction group did not improve significantly from Furthermore, the scale of interpersonal sensitivity was
the initial and follow-up consultations. higher in those with cluster B and cluster C personality dis-
order.41 Ko et al. suggested that low interpersonal sensitivity
predicted remission of Internet addiction in adolescents.7
Discussion Further research is warranted to examine the effect of
psychotherapy for modification of interpersonal sensitivity
This prospective study examined the bidirectionality of to prevent the development of Internet addiction.
psychopathology and Internet addiction among college stu- The present study determined that baseline paranoid
dents in Taiwan. The results indicated that severe inter- ideation predicted the development of Internet addiction 1
personal sensitivity and paranoia symptoms on these SCL-90- year later. Paranoid ideation is associated with excessive
R subscales might predict the incidence of Internet addiction fear or anxiety.42 Regarding the neurobiology of the
at 1-year follow-up. The severities of obsession-compulsion, development of paranoia, Corlett et al. reported the
interpersonal sensitivity, paranoid and psychoticism in the aberrant prediction error in fronto-striatal learning systems
nonaddiction group significantly decreased during the one- and inappropriate engagement of the brain’s fear system.43
year period of follow-up, whereas the severities of all di- Moreover, a review of neuropsychological and neuro-
mensions of psychopathology in the internet addiction group imaging findings of Internet addiction identified fronto-
did not improve significantly during the same period. striatal loops as a main neural correlates of addictive
behavior.44 In accordance of previous studies, individuals
Effects of psychopathology on internet addiction with avoidance coping style was positively correlated with
development Internet addiction,29 while higher levels of emotional and
avoidant coping were associated with higher levels of
In accordance with the results of previous studies,7,24 the paranoia.30 However, the present study assessed self-
present study determined that high interpersonal sensitivity reported paranoid ideation on the SCL-90-R but not
Psychiatric symptoms and Internet addiction 1097

Table 1 Comparisons between groups I and II and groups III and IV of demographic characteristics and psychiatric symptoms.
Group I (n Z 248) Group II (n Z 20) p Group III (n Z 26) Group IV (n Z 30) p
n (%) or mean (SD) n (%) or mean (SD) n (%) or mean (SD) n (%) or mean (SD)
Gendera
Female 129 (50.0) 11 (55) .797 15 (57.7) 14 (46.7) .410
Male 119 (48.0) 9 (45) 11 (42.3) 16 (53.3)
Age (years)b 22.3 (2.0) 22.4 (1.9) .729 21.6 (1.2) 22.6 (1.9) .019
SCL-90-Rc
Somatization 4.7 (5.6) 7.6 (6.6) .026 9.8 (8.7) 10.9 (9.5) .705
Obsession-compulsion 8.1 (5.8) 10.9 (4.9) .015 13.8 (6.7) 14.1 (7.1) .915
Interpersonal sensitivity 6.2 (5.4) 9.2 (5.0) .006 9.5 (6.7) 11.3 (7.5) .370
Depression 7.3 (6.5) 10.3 (5.3) .010 14.0 (8.2) 13.7 (9.0) .687
Anxiety 5.5 (4.8) 6.1 (3.9) .306 10.1 (6.6) 10.3 (7.3) .961
Hostility 2.7 (3.2) 3.5 (4.1) .441 5.0 (4.1) 5.5 (5.1) .875
Phobia 1.7 (2.5) 2.5 (2.1) .026 4.5 (4.4) 4.0 (4.2) .740
Paranoid 3.4 (3.6) 6.1 (4.1) .001 5.5 (4.4) 6.4 (4.2) .365
Psychoticism 3.7 (4.1) 5.3 (3.3) .015 5.5 (4.8) 6.4 (5.1) .519
SCL-90-R: Symptom Checklist-90-Revised.
Group I and II: The participants deemed nonaddicted at baseline assessment were stratified into groups I and II based on the follow-up
evaluation as nonaddicted or addicted, respectively.
Group III and IV: The participants deemed addicted initially but who had remitted on follow-up were assigned to group III, whereas those
who remained addicted were assigned to group IV.
a
Chi-square test.
b
t test.
c
Mann-Whitney U test.

through face-to-face interviews and thus could not deter- environment in which they feel comfortable and can
mine the real characteristics of the paranoid ideation that decide with whom they wish to interact and in what ac-
the participants reported. Paranoid ideation may make tivities they wish to participate. Thus, the risk of devel-
college students feel unsafe when they go outside and oping Internet addiction may increase among college
interact with others. The Internet may provide them an students with high paranoid ideation.

Table 2 Psychiatric symptoms on Symptom Checklist-90-Revised at the initial and follow-up consultations among the par-
ticipants with and without Internet addiction at the initial consultation: Wilcoxon signed ranks test.
Initial investigation Follow-up investigation Z p
Mean (SD) Mean (SD)
Internet addiction group (n Z 56)
Somatization 10.4 (9.0) 8.4 (9.2) 1.869 .062
Obsession-compulsion 13.9 (6.9) 11.7 (8.3) 2.223 .026
Interpersonal sensitivity 10.5 (7.1) 9.2 (6.6) 1.432 .152
Depression 13.9 (8.6) 12.9 (10.5) -.738 .460
Anxiety 10.2 (6.9) 8.9 (7.6) 1.912 .056
Hostility 5.3 (4.7) 4.6 (4.7) 1.269 .204
Phobia 4.2 (4.3) 3.5 (4.3) 1.285 .199
Paranoid 6.0 (4.3) 5.3 (4.9) -.973 .330
Psychoticism 6.0 (5.0) 6.7 (6.7) .816 .415
Non-Internet addiction group (n Z 268)
Somatization 4.9 (5.7) 4.0 (5.4) 2.605 .009
Obsession-compulsion 8.3 (5.7) 7.1 (6.2) 4.088 <.001
Interpersonal sensitivity 6.4 (5.4) 4.9 (5.0) 5.112 <.001
Depression 7.6 (6.5) 6.8 (7.4) 2.493 .013
Anxiety 5.6 (4.8) 5.4 (5.6) 1.041 .298
Hostility 2.8 (3.3) 2.5 (3.5) 1.847 .065
Phobia 1.8 (2.5) 1.5 (2.5) 2.652 .008
Paranoid 3.6 (3.7) 2.8 (3.8) 4.624 <.001
Psychoticism 3.9 (4.0) 3.2 (4.4) 3.571 <.001
1098 Y.-J. Lin et al.

Effect of internet addiction on psychopathology college students with psychiatric symptoms to prevent the
development of Internet addiction. Furthermore, strategies
Normally, the skills of interpersonal interaction, social implemented for early intervention in Internet addiction
cognition and communication mature with age in early are therefore critical to college students for improving
adulthood as the brain grow45,46; as time go by, the in- their psychological symptoms.
dividuals may develop ability and accumulate experiences
to analyze the interpersonal and intrapersonal stimuli and Funding sources
cope with them efficiently. The individuals may establish
their confidence to manage multidimensional difficulties This study was supported by Kaohsiung Medical University
encountered in daily lives and therefor feel less anxious Hospital (Grant No. KMUH103-3M38). The funding supported
toward unknown. The matureness may partially account for conduction of the study, collection of data, and preparation
the result of the present study that the severities of of original study report. No funding was available for
obsession-compulsion, interpersonal sensitivity, paranoid writing manuscript or publishing article.
and psychoticism in the nonaddiction group significantly
decreased in follow-up consultations. However, the sever-
ities of all dimensions of psychopathology in the internet Authors’ contribution
addiction group did not improve significantly 1 year later.
Internet addiction may reduce the opportunities for college YJL: Study concept and design, obtained funding, study
students to engage in face-to-face social activities and supervision.
further compromise Internet users’ ability to learn what RCH: Study concept and design, analysis and interpretation
others think, how to interact with peers maturely, how to of data.
behave in a socially acceptable manner, and how to develop TLL: Analysis and interpretation of data, statistical
empathy. In addition, evidence of decreased brain func- analysis.
tional connectivity in circuits linking cortical to subcortical CFY: Study concept and design, analysis and interpretation
regions was found in adolescents with Internet addiction.47 of data, statistical analysis, obtained funding, study
College students with Internet addiction may be less supervision.
mature in both brain functional connectivity and personality All authors had full access to all data in the study and take
construction than those without Internet addiction. responsibility for the integrity of the data and the accuracy
of the data analysis.
Limitations
Ethics approval and consent to participate
This study had several limitations that should be considered
when interpreting the results. First, the study data were The study was approved by the Institutional Review Board
exclusively self-reported. Therefore, using only one data of Kaohsiung Medical University Hospital.
source may have influenced our findings and resulted in
shared-method variance. Second, SCL-90-R is more useful Consent for publication
for measuring static mental states than psychiatric di-
agnoses. Hence, we could not infer from our result the Not applicable.
bidirectionality of the relationship between Internet
addiction and psychiatric diagnoses as previous studies do.
Third, the number of members of the Internet addiction Declaration of Competing Interest
group was relatively small. This highlights the necessity of
large perspective studies with longer follow-up periods. The authors have no conflicts of interest relevant to this
Fourth, we did not assess the content of the Internet ac- article.
tivity. In addition, present study utilized only two assess-
ments since the ideal methodological approach to tackle
Acknowledgments
bidirectional relationship often demand three or more
assessments.
This study was supported by Kaohsiung Medical University
Hospital (Grant No. KMUH103-3M38).
Conclusion

This prospective investigation in college students demon-


Appendix A. Supplementary data
strated that severe interpersonal sensitivity and paranoia
symptoms might predict the incidence of Internet addiction Supplementary data to this article can be found online at
at 1-year follow-up. The college students with internet https://doi.org/10.1016/j.jfma.2019.10.006.
addiction did not have significant improvement in the se-
verities of psychopathology during the one-year period of References
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