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Effect of Self-Care Management Program on the Quality of Life and Self-Efficacy


of Geriatric Patients with Parkinson's Disease. World Journal of Nursing
Sciences 3S: 56-72, 2014

Article · March 2014


DOI: 10.5829/idosi.wjns.2014.56.72

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World Journal of Nursing Sciences 3S: 56-72, 2014
ISSN 2222-1352
© IDOSI Publications, 2014
DOI: 10.5829/idosi.wjns.2014.56.72

Effect of Self-Care Management Program on the Quality of Life and


Self-Efficacy of Geriatric Patients with Parkinson's Disease
1
Marwa Ibrahim Mahfouz, 1Hanaa Abou El-soued Hussein and 2Magda Mahmoud Mohammad

1
Gerontological Nursing, Alexandria University, Alexandria, Egypt
2
Gerontological Nursing, Damanhur University, Damanhur, Egypt

Abstract: Parkinson's disease is one of the long-term multifocal neurological conditions which have undesirable
consequences on geriatric patients' independence and quality of life (QOL). So, those compromised patients
need to be learn about personalized self-care interventions adopted to their needs in order to achieve finest
control over their health condition, feel confident in one’s ability to manage such progressive and degenerative
symptoms and develop an acceptable level of progress in all life domains and overall wellbeing. The study
aimed to determine the effect of self- care management program on the quality of life and self-efficacy of geriatric
patients with Parkinson's disease. The study was carried out in neuropsychiatric outpatient clinic of El-Hadara
Orthopedic and Traumatology University Hospital in Alexandria, Egypt. The study sample consisted of 22
geriatric patients with idiopathic Parkinsonism. Five tools were used in this study; Parkinson's disease Geriatric
Patients' Demographic and Health Information Structured Interview Schedule, Mini-mental State Examination,
the Modified Hoehn and Yahr Staging Scale, the Self-Efficacy for Managing Chronic Disease Scale and the
39-items Parkinson's Disease Questionnaire. Results showed that less than two thirds (63.3%) of the studied
patients with Parkinson's disease reported poor quality of life of total domains. The factors most closely
associated with poor QOL were mobility, body discomforts and impaired daily activities. The improvements of
these features therefore become an important target in the self-care management of the disease developed in
this study, in addition to the other domains affected passively with PD. After application of the educational
program, an observed measured improvement in both PD geriatric patients' quality of life and their self-efficacy
was evident immediately post program which returned back gradually during the follow-up weeks later,
although still significant. Further, PD suffers’ QOL was greatly linked and correlated significantly with their
self-efficacy. It could be concluded that application of self-care strategies is effective in increasing the quality
of life of seniors who suffer from Parkinson's disease and help in improvement of their self-efficacy. The authors
recommended that self-care interventions should be incorporated into the routine nursing practice for geriatric
patients with Parkinson's disease and involving their family care-givers to affect positively their quality of life
and consequently their self-efficacy.

Key words: Personalized-Care Strategies Parkinson’s Disease Superiority Of Life Confidence In One’s
Own Abilities Diseased Seniors

INTRODUCTION most common neurodegenerative diseases that only


outnumbered by Alzheimer’s dementia in older adults [2].
The unknown etiology and unpredictable course of It is thought that the neurochemical imbalances seen in
Parkinson's disease progression make it one of the more PD disrupts the neural circuitry of the basal ganglia
mysterious and complex of all neurological disorders [1]. resulting in reduction in the size and speed of sequential
Parkinson's disease (PD) is a progressively debilitating movements and manipulative tasks, in addition to
disorder predominantly causes motor and non-motor irregularity in automated cognitive events, mood,
dysfunctions and possesses the second ranking of the behavior and all other disease features [3].

Corresponding Author: Marwa Ibrahim Mahfouz, Gerontological Nursing, Alexandria University, Alexandria, Egypt.
E-mail: marwa871975@gmail.com.
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The diagnosis of PD is done clinically as the disease relationships and activities. Although the inner feelings
hasn’t any biomarkers. Out of all clinical data, response to are intact, the incongruence may lead to social
levodopa is the most discriminatory in the differential embarrassment among these patients [11].
diagnosis of PD from other types of Parkinsonism. While Hypophonia and other voice changes occur in
scientists agree that there is a dopamine deficiency in 80-90% of these patients; and 45-50% has articulation
persons with PD, the mainly cause of the dopamine loss changes. Patients are cognizant of their distractibility and
still remains unidentified A mutation in LRRK2 gene is the difficulty with word-finding and thought processing while
most frequent cause of the disease known to date [4]. engaging in conversation [12]. As a consequence of their
The worldwide incidence of PD is thought to vary speech and communication difficulties, PD older adult
between 1.5 and 22 patients/100 thousands patients reported that they experienced loss of self-
population/year and millions more remaining undiagnosed esteem, loss of dignity, humiliation and altered
with a widely ranged prevalence in door to door surveys socialization processes ranging from apprehension,
[5]. PD prevalence is 1.3% in men versus 1.6% in women disengagement, to complete withdrawal. Written
[6]. Unfortunately, Egypt ranks the third in the world communication is further affected due to tremors resulting
among the countries of the highest prevalence rate of the in the typical micrographic handwriting seen in PD [13].
disease with a rate of 1.103 per 100 thousands population, Although drug therapy is the major treatment
specifically in the rural areas, south of Cairo along the modality for the disease, it may have its own reverse
River Nile, probably because of poverty [7]. consequences and side effects that can also impact the
Quality of life (QOL) of geriatric patients with PD QOL for the patients causing symptoms such as
comprises the total effect that this condition has on a dyskinesia, hedonistic dopamine dysregulation syndrome,
person's bio-psycho-social wellbeing and his or her actual freezing, orthostatic hypotension, hallucinations,
and desired life. For people living with chronic diseases psychoses and visual disturbances. “Off” states
such as PD, QOL may change daily and even frequently potentially occur when PD medications wear off and are
within the course of a day, as they struggle to adapt to no longer available to control the symptoms until more
and manage the challenges which the disease thrusts medication is given and reaches an adequate blood level
upon them [8]. to control patients' manifestations. Non-adherence to
Often the PD older adult patient experiences a prescribed drug and other treatment regimens could result
constellation of biological, psychological or emotional, in negative consequences to patients' quality of life, such
cognitive and social symptomatology. The physical as increased frequency of “on-off’ states, falls, injuries
symptoms of PD typically affecting QOL are tremor, and others [14].
rigidity, bradykinesia and troubles with manual dexterity. Fortunately, there are several other beneficial
Some of the aspects that affected intensely in QOL for underutilized treatment modalities available to aid in the
those patients and their families include: impaired management and control of PD symptoms that include
mobility, balance and nutrition; sleep disturbances, exercises, environmental design, rehabilitation and social
fatigue, altered libido, blurred vision and other autonomic support systems, all of which may be effective in
nervous system-related aspects. These features can make improving QOL for those patients [15].
it difficult for PD patients to perform routine activities of In this respect, PD older adult patients, like patients
daily living (ADLs), such as dressing, bathing and with other chronic diseases, have to learn how to live with
grooming; getting out of bed or arising from a seated and self-manage their symptoms and disease-related
position; and walking or climbing stairs [9]. issues on a daily basis. Central to the ability of self-
While physical symptoms are critical to the clinical managing their disease is having the confidence that they
diagnosis, PD is not solely a motor control and movement have the knowledge, skills and ability, i.e., self-efficacy, to
disorder. Dementia, depression and anxiety are common carry out the required behaviors and tasks to achieve the
psychological syndromes reported [10]. Not only do older desired goals. Self-care is vital necessary for Parkinson
adult patients with PD struggle with the physical and diseased older adults and involved the ability of
psychological impairments of the disease, the dissociation individuals, families and communities to promote health,
of emotional expressivity (expressive dysprosodia) and prevent disease and cope with illness and disability with
facial expression has a profound effect on their social or without the support of a healthcare provider [16].

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Because in our Egyptian community, the concept of Research Setting: This study was conducted in
self-care management for PD is out the light of health care neuropsychiatric outpatient clinic of El-Hadara
interest, patients suffer from more confusing everyday Orthopedic and Traumatology University Hospital. It is
struggles, for which lacking essential knowledge and affiliated to Alexandria University and it was selected as
practice to effectively deal with. one of the biggest university hospitals that provided best
services for neurological and psychiatric diseases in
Significance of the Study: Self-care management through Alexandria, Egypt.
PD patient education should be directed toward avoiding Additionally, it includes sections for orthopedic
or limiting functional disability, achieving a slower surgery and emergency operations, outpatient clinics and
progress in this chronic disease that considered incurable CT scan. The hospital power reached 449-bed. The
and maintaining independent living for as long as neuropsychiatric outpatient clinic is specialized in
manifestation of neuropsychiatric disorders which specify
possible. Extant research is limited regarding the role of
five days per week for providing medical services from
patient education for disease self-management in
Saturdays along Wednesdays. However, only Sundays
Parkinson's disease and ultimately, the influence of such
are determined for treating and following PD patients
factors on patient's QOL and self-efficacy for managing
whose number amounted to 31 patients (28 geriatric
the disease. Successful self-care will not occur unless the
patients with different degrees of idiopathic PD 60 years
views, opinions, beliefs and attitudes of patients
and over “only those with idiopathic PD which related to
themselves are considered as key components of unknown etiology with certain degrees were selected
therapeutic encounters. according to inclusion criteria” and 3 patients with other
To what extent the geriatric patients with PD could forms of Parkinsonism under 60 years old declined later)
improve their well-being and resume their familiar lifestyle,
becomes a critical issue. Improvement in quality of life and Subjects: A convenient sample of 22 geriatric patients
the ability to retain activities of daily living should (out of 28) of both sexes diagnosed with idiopathic
therefore be the goals of outcome criteria for the parkinsonism (PD) attending the previous clinic for follow
gerontological nurses in clinical trial designs focused on up of their therapeutic regimen with the following criteria,
the elderly with PD. So, there is a growing need to identify were eligible to participate and enrolled in the current
the effectiveness of patient education in enhancing PD study:
geriatric patients' self-reported QOL and self-efficacy
through self-management program. Older adults 60 years and above (as Parkinsonism
Aim of the Study: To determine the effect of self-care can affect people of different age due to known
management program on the quality of life and self- causes which differ from Parkinson's disease of
efficacy of geriatric patients with Parkinson's disease. unknown etiology).
Had disease duration between 1-5 years. Because of
Research Hypotheses: their limited experience with the disease
manifestations, geriatric people diagnosed with PD
Geriatric patients with Parkinson's disease who for less than one year were excluded from this study
receive the proposed self-care strategies exhibit and those over 5 years will be also not included
because of the progressive nature of the disease (get
higher quality of life post the intervention than
more worse) takes place over a period of 5 years,
before.
usually accompanied severe disabilities that obstruct
Geriatric patients with Parkinson's disease who
patient abilities to follow self-care program
receive the proposed self-care strategies exhibit
instructions and being dependent on others to fulfill
improved self-efficacy post the intervention than
needs (according to specialist’s recommendation of
before.
duration) .
Had no other chronic disabling illnesses or
MATERIALS AND METHODS neurological disorders (i.e. CV Stroke), Participants
with an illness in addition to PD, that impacted
Research Design: The study used a pretest-posttest and activities of daily living might have difficulty
follow-up research design. separating those experiences unique to PD.

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World J. Nursing Sci., 3S: 56-72, 2014

Compliance with a stable dose of medications for at Tool III: The Modified Hoehn and Yahr Staging Scale:
least a month. The original widely- used H & Y scale developed by
Were able to ambulate independently, or with an Hoehn and Yahr [19] to describe the clinical progression
assistive device. or the severity level of PD symptoms by observing the
Score of 26 or greater in Mini-Mental State Exam patient in both standing and sitting position.
(MMSE) (normal = 26 in PD) or with mild cognitive The scale was criticized as lacking sensitivity to
impairment (18- 25) measure the gradual deterioration of the PD patient’s
Were at a modified Hoehn and Yahr stages (an condition. Thus, a modified version was proposed and the
assessment of disease severity) of 2, 2.5 and 3. Since, scale was further divided into eight stages, ranging from
it was likely that those at a modified Hoehn and Yahr 0 to 5 (“Stage 0 = No signs of disease” to “Stage 5 =
stage of 0 or 1 (unilateral disease) have not Wheelchair bound or bedridden unless aided”), with half-
experienced significant life-style changes, so only point gradations between stages 1 and 2 (1.5) and stages
those at stage 2 , 2.5 and 3 (starting from bilateral 2 and 3 (2.5). Then it had been added to the Unified
disease without impairment of balance to mild to Parkinson’s Disease Rating Scale (UPDRS).
moderate bilateral disease; some postural instability;
and physically independent) were included in this Tool IV: The Self-Efficacy for Managing Chronic
study Disease 6-Item Scale: A short scale was developed by
Lorig et al. [20] to measure the self-efficacy outcome in
Tools: In order to fulfill the objective of the study, five Chronic Disease Self-Management Program. The scale
tools were used covers several domains that are common across many
chronic diseases, symptom control, role function,
Tool I: PD Geriatric Patients’ Demographic and Health emotional functioning and communicating with
Information Structured Interview Schedule: Developed physicians.
by the researchers and completed by all participants The score for each item is the number circled. If two
verbally prior to the initial interview. Data were collected consecutive numbers were circled, the lower number
on age, gender, educational level, marital status, (less self-efficacy) is coded. If the numbers are not
occupational background, socioeconomic status, & onset consecutive or more than two items were missing, score
of PD diagnosis, other diagnoses and current of the item was omitted. The score for the scale is the
medications, use of assistive devices, participation in mean of the six items and higher number indicates higher
medical insurance system and patient’s rate of health. self-efficacy.

Tool II: Mini-Mental State Examination (MMSE): The Tool V: The 39- item Parkinson’s disease Questionnaire
MMSE is an effective screening tool that used to (The PDQ-39): The PDQ is a set of 39 self-administered,
systematically and thoroughly assess mental status of PD- specific multi-dimensional quality of life questions
community dwelled older adults. It is a 30-question with eight discrete domains. It was developed by
measure that developed by Folstein et al . [17], translated Peto et al. [21] and designed to measure key QOL areas
into Arabic language by Elokl [18] and approved to be that had been adversely affected by PD during the
valid and reliable (r= 0.93). preceding month.
It tested ten areas of cognitive function: memory, The eight dimensions are: (a) mobility (10 items,
orientation to time and place, attention, calculation, negotiated mobility problems such as difficulty doing the
naming, repetition, registration, language, praxis and leisure activities or walking 100 yards) (b) activities of
copying of a design. The MMSE has two sections. daily living (6 items, represented a variety of ADL
The first section has a maximum score of 21 and focuses limitations such as cutting food or dressing self) (c)
on attention, memory and orientation and requires vocal emotional well-being (6 items, declared enormous
participation from the patient. The second section has a emotional disturbances such as being depressed or
maximum score of 9 and focuses on the patient’s ability to worried about the future), (d) stigma (4 items, pointed out
both name and follow written and verbal instructions. The the social difficulties affected the lives of PD patients
maximum score is 30. For PD, a score of 26 or higher is an such as avoid eating or drinking in public), (e) social
indicative of cognitive intact functions, while that ranged support (3 items, discussed the level of support PD
from 18-25 indicates mild cognitive dysfunction. patients perceived from daily social interactions and

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World J. Nursing Sci., 3S: 56-72, 2014

relations such as problems concerning lack of support juries of (5) experts in the field. Their suggestions
from family or close friends) , (f) cognitions (4 items, and recommendations were taken into consideration.
involved problems in the cognitive areas such as memory Cronbach’s coefficient alpha test was used to
and concentrations), (g) communication (3 items, ascertain the reliability of tools. Test indicated that
addressed the communication inappropriateness such as tool III, IV and V were 85.4% reliable, 76.8% reliable
speech difficulties impaired communication with others) and 91.3% reliable respectively. PD quality of life
and (h) bodily discomfort (3 items, described different domains ranged from 0.572 to 0.849 in reliability test).
bodily undesirable feelings such as pains, cramps and Pilot study was carried out on 4 older adults with PD
aches). not included in the study, selected from geriatric
Respondents are requested to affirm one of 5-point medicine unit at Alexandria Main University Hospital
ordinal response scoring system: 0 = never had this during their follow up appointments in order to
problem, 1 = occasionally, 2 = sometimes, 3 = often, 4 = ascertain the relevance, clarity and applicability of
always have this problem (Likert scale) according to the the tools, test wording of the questions and estimate
frequency of patients’ experience difficulties across the the time required for the interview. Based on the
eight subscales’ items which reflect the impact of the obtained results, the necessary modifications were
disease on patients’ health status , functioning and done.
wellbeing. Each dimension total score range from 0 (never
have difficulty) to 100 (always have difficulty). Lower Development of the Self-Care Management Program:
scores reflect better QOL. Dimension score equals sum of
scores of each item in the dimension divided by the Self-care skills and strategies were developed by the
maximum possible score of all the items in the dimension, researchers after reviewing the most recent related
multiplied by 100. literature. Self-management skills for PD comprised
Total Score equals sum of scores for questions 1-39 areas related to a variety of professional domains,
divided by four, multiplied by 39 and then multiplied by including importance of self- management program
100. and basic information about PD, skills for managing
one’s medications; diet and physical exercise,
Study Method: functional activities and home /environmental
modifications; managing non motor behavior,
An official letter was forwarded to the hospital’s memory problems, eating and swallowing difficulties,
administrator to obtain the permission to attend the eye and sleep disorders, pain and motor fluctuations,
clinic. Then after, the study purpose was explained to skin and foot care, bladder and bowel function, fall
both the hospital’s administrator, the head of the prevention, dealing with anxiety and depression,
clinic and nursing staff as well and a written speech intelligibility, social communication; and
permission was obtained in order to gain their identification and access of appropriate social
support and cooperation during the application of support systems.
the study interventions.
For proper conduction of this study, three phases Primary Assessment Outcome and Fieldwork:
were implemented; assessment or preparation phase,
program conduction phase and evaluation (follow Each interview took approximately 30- 45 minutes,
up) phase. depending on the participant's comfort level and will
take place in the waiting area of the clinic using tools
Phase One: “Assessment or Preparation Phase”: from I to V. The preferred method used of
Development of Tools: interviewing is one-on-one in the presence or
absence of family members or caregivers. A caregiver
Tool I was developed by the researchers based on may be defined as any person with the exception of
recent relevant literature to assess demographic and medical care providers (i.e., significant other, family
health information of the Parkinsonian patients. The and sitter) providing care to the person with PD.
Arabic version of tool II was used in this study. Collection of initial data covered a period of two
Tools from III to V were translated into Arabic months and half, from the beginning of June 2011 till
language by the researchers and were validated by the mid of August 2011.

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Phase Two: “Program Conduction Phase”: The total period of data collection, including the
three phases covered a period of 17 months and a
Before the conduction of the educational and skills- half, from the beginning of June 2011 till the mid of
related sessions and after the first joint clinic visit; January 2013. Then, the difference between pre-
researchers informed participants of any potential intervention and post-intervention scores was
benefits that they may experience by being in the determined through using the proper statistical
study which included (a) increased knowledge of and analysis.
self-confidence (self-efficacy) regarding management
of PD care and other health issues, (b) increased Ethical Consideration: Ethical consideration was applied
problem-solving skills to deal with health-related through participants' informed written consent to
issues, (c) opportunities for increased social participate in the study. The participants’ rights were
interaction, (d) and increased QOL. protected by explaining the purpose and significance of
The program conducted on group bases of 4 groups the study. Participants were reassured that their
in total (2 groups with 6 elders each and two 5- elder responses will be kept anonymous and no remarks will be
groups), 20-35 minutes session/week on Sundays made to identify the patients' identity. The patient was
(the only day determined for PD patients for informed that participation in the study is voluntary and
receiving care and follow up, taken into consideration can withdraw at any time and that withdrawal will not
that patient went to the clinic once per month), affect the level of services and care provided.
preceding by quarter an hour summary of important
previous learnt knowledge/skills and answering Statistical Analysis: The collected data were coded and
related questions. analyzed using PC with SPSS version 20 and tabulated
Teaching methods included lectures, group frequency and percentage were calculated. Descriptive
discussion, role-playing, brainstorming, statistics as frequency, distribution, mean and standard
demonstration and re- demonstration, models, deviation were used to describe different characteristics.
pictures, real life demonstration, problem solving and The Chi-square test and Monte Carlo test were used
mastery experience (i.e. trying out the skills for testing relationship between categorical variables.
introduced on the self- care program). Univariate analyses, including: t-test was used to test the
The total number of sessions was 56 sessions, 14 significance of results of quantitative variables and to
sessions per each group (one discussed topic every compare the means between two unrelated groups on the
meeting with a break period of 30 minutes providing same continuous, dependent variable.
snacks and exercises practice from the second week The one-way analysis of variance (ANOVA) is used
along with all sessions). This phase covered a period to determine whether there are any statistically significant
from the mid of August 2011 till the mid of October differences between the means of two or more
2012. independent groups (F Test). The level of significance
Handouts to improve learning and action plan selected for this study was p value equal to or less than
calendar were prepared and given to each participant 0.05.
to identify obstacles hinder the achievement of
needed goals. RESULTS

Phase Three: “Evaluation/Follow up Phase”: Table (1) illustrates that the age of the study subjects
ranged from 60 to 77 years with a mean of 63.8±4.7 years.
Post the implementation of the self-management Those in the age group of 60 years to less than 65 years
program, reassessment of the quality of life domains constituted more than one half of all studied PD older
and self-efficacy of the participants were done by the adults (59.1%). More than three quarters (77.3%) of them
researchers two times; once directly after the were males, while being married (91.0%) and illiterate
conduction of self-care strategies and at the sixth (54.6%) characterized the social and educational
week of the program implementation. The second background of the study sample.
assessment outcomes was determined during 3 Table (2) shows that 50.0% of the study subjects had
months evaluation from the mid of October 2012 to health problems other than Parkinson's disease. Around
the mid of January 2013. three quarters (72.3%) of them had disorders related to

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Table 1: Description of the studied subjects according to their socio-demographic information


The studied subjects (no. = 22)
------------------------------------------------------------
Socio-demographic information Number %
Age (in years)
60 years- 13 59.1
65 years- 6 27.3
70 years 3 13.6
Min-Max 60 -77
Mean ± SD 4.7± 63.8
Sex
Male 17 77.3
Female 5 22.7
Marital status
Married 20 91.0
Divorced 1 4.5
Single 1 4.5
Educational level
Illiterate 12 54.6
Primary education 5 22.7
Preparatory education 2 9.1
Secondary education 2 9.1
University education 1 4.5

Fig. 1: Distribution of the study subjects according to self-evaluation for their health condition

cardiovascular system such as hypertension, ischemic were the most common drugs consumed without
heart diseases and heart failure. Diabetes mellitus and a prescription (90.0% and 80.0% respectively) among
history of previous fall were reported with an equal 45.5% of the subjects who consumed over the
percent (36.4%). While, 18.2% suffered from counter (OTC) medications. 54.5% of PD elderly
psychological problems. The same table revealed also patients used assistive devices; including eye glasses
that more than two thirds (68.2%) reported sensory (83.3%) followed by canes for mobility (50.0%) and
problems in the form of visual problems (66.7%), pain hearing aids (8.3%). Further, the vast majority (90.9%) of
(40.0%) and smell problems (13.3%). In addition to the the study subjects had no health insurance or enough
dopaminergic agents, more than one half (54.5%) of the income for follow up their current diagnosis (Parkinson's
elderly with PD consumed prescribed medications for disease).
different disorders. Cardiovascular drugs are the most Figure (1) reflects that more than one half (59.0%) of
common consumed drugs 58.3%, followed by the study subjects evaluated their health condition as
hypoglycemic agents 33.3%. Analgesics and laxatives moderate in wellness.

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Table 2: Description of the studied subjects according to their clinical data


The study subjects (no. =22)
--------------------------------------------------------------
Health status Number %
A. Health problems other than Parkinson's disease
Yes 11 50.0
Disorders related to: #
Cardiovascular system 8 72.3
Endocrinal system 4 36.4
Previous fall 4 36.4
Psychological problems 2 18.2
Gastrointestinal system 1 9.1
Respiratory system 1 9.1
No 11 50.0
B. Sensory-perceptual problems:
Yes 15 68.0
Type of sensory- perceptual problems: #
Visual problems 10 66.7
Sensation problems (pain) 6 40.0
Smell problems 2 13.3
No 7 31.8
C. Current prescribed medication consumed
Yes 12 54.5
Types of medication: #
Cardiovascular medication 7 58.3
Diabetes medication 4 33.3
Eye drops 2 16.7
Anxiolytics 2 16.7
Gastrointestinal medication 1 8.3
Respiratory medication 1 8.3
Sleep enhancer 1 8.3
Antiepileptic 1 8.3
No 10 45.5
D. Over the counter medication consumed
Yes 10 45.5
Types of medication: #
Analgesics 9 90.0
Laxatives 8 80.0
Antacids 2 20.0
No 12 54.5
E. Assistive devices used
Yes 12 54.5
Types of assistive devices: #
Eye glasses 10 83.3
Cane 6 50.0
Hearing aids 1 8.3
No 10 45.5
F. Have health insurance
No 20 90.9
Yes 2 1.9
G. Enough income for follow up
No 20 90.9
Yes 2 9. 1
#=more than one response was given

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Table 3: The effect of self-care management program on the quality of life of geriatric patients with Parkinson's disease
Elders' Mean Scores Elders' Mean Scores Elders' Mean Scores
Pre-program Immediate Post-program 6 weeks Post-program Test of significance
--------------------------------------------------------------------------------------------------------- (ANOVA Test)
Total percent score** Total percent score** Total percent score** ----------------------------
PDQ_39_SI sub items Mean ± SD Mean ± SD Mean ± SD P1 P2
Mobility 71.25±14.6 50.5±14.7 57.9±16.1 F:2.706 F:6.101
P:0.064 P:0.004*
Activity of daily livings (ADLs) 59.8±14.8 44.9±15.7 49.6±14.8 F:6.923 F:3.918
P:0.001* P:0.015*
Emotional wellbeing 59. 3±17.6 40.3±14.5 48.1±17.3 F:0.864 F:1.116
P:0.595 P:0.435
Stigma 58.5±15.5 40.9±13.2 45.4±14.0 F:3.001 F:4.455
P:0.040* P:0.009*
Social support 59.4±24.5 44.3±16.5 51.8±18.5 F:1.942 F:2.027
P:0.138 P:0.123
Cognition 60.5±16.2 38.3±11.2 43.4±15.1 F:6.787 F:3.565
P:0.001* P:0.021*
Communication 59.4±19.2 44.6±11.9 50.3±14.8 F:1.872 F:2.816
P:0.151 P:0.047*
Bodily discomfort 69.7±18.10 43.9±8.5 57.1±14.6 F:0.909 F:1.503
P:0.527 P:0.244
PDQ_39_SI TOTAL Score 63.3±11.2 44.4±10.4 51.2±11.8 F:11.715 F:3.584
P:0.003* P:0.062
F: ANOVA test P: p value of ANOVA test
Significant P =0.05 P ** Lower score reflects better QOL P1: Stands for adjusted Bonferroni p-value for ANOVA with repeated measures for comparison
between pre with immediate post-program
P2: Stands for adjusted Bonferroni p-value for ANOVA with repeated measures for comparison between pre with 6 weeks post-program

Table (3) illustrates that there was an observed (50.5±14.7) in comparison to its level before (71.25±14.6)
improvement in overall score of quality of life of geriatric which proved to be insignificant (F= 2.706, P= 0.064).
patient with Parkinson's disease immediately after the Fortunately, the mobility is still slightly improved after six
application of self-care management program and the weeks (57.9 ±16.1) if compared to its level prior the
difference is statistically significant (F= 11.715, P=0.003*). program (71.25±14.6) with a statistically significant
After six weeks duration from the end of the program, the difference (F= 6.101, P= 0.004*). In addition, bodily
quality of life was still improved (51.2±11.8) in comparison discomfort domain was improved immediately after the
to its level prior the application of the program (63.3±11.2) program and after six weeks (43.9±8.5, 57.1±14.6
with no statistically significant difference (F=3.584, respectively) and the difference was not statistically
P= 0.062). Generally, after six weeks, all domains of quality significant (F= 0.909, P= 0.527, F= 1.503, P=0.244
of life were slightly returned back in comparison to its respectively). Furthermore, Activity of daily livings of
level immediately after the application of the program. geriatric patients with Parkinson's disease was
Immediately after the application of self-care significantly improved immediately after the program and
management program, the highest level of quality of life after six weeks (44.9±15.7, 49.6±14.8 respectively) in
was reported in cognition which significantly improved comparison to its level before it (59.8±14.8) with
(38.3±11.2) in comparison to its level prior the application statistically significant difference (F= 6.923, P= 0.001*,
of the program (60.5±16.2) and the difference was F= 3.918, P=0.015* respectively).
statistically significant (F= 6.787, P= 0.001*). Moreover, The program elevated the social support domain of
after six weeks, the cognition was still better (43.4±15.1) QOL immediately after its application and then next the six
in comparison to its level before the application of weeks period (44.3±16.5, 51.8±18.5 respectively) in
the program with a statistically significant difference comparison to its level before it (59.4±24.5) with no
(F= 3.565, P= 0.021*). statistically significant difference (F= 1.942, P= 0.138,
On the other hand, as the physical function was the F= 2.027, P=0.123 respectively). Communication
most deteriorated aspect of QOl; the mobility was slightly domain experienced nearly the same level of
improved immediately after the application of the program enhancement immediately after the program (44.6±11.9)

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Table 4: The effect of self-care management program on Self-efficacy of geriatric patients with Parkinson's disease
Mean ± SD Scores ** Test of significance (ANOVA Test)
------------------------------------------------------------------------------------------ ---------------------------------------
Item Total allowed score Pre-program Immediate Post-program 6 weeks Post-program P1 P2
Self-efficacy 60 21.2±7.2 30.6±5.7 29.1±5.7 F: 3.376 F: 2.102
P: .038* P:0.135
F: ANOVA test P: p value of ANOVA test
*Significant p=0.05 **Higher number indicates higher self-efficacy P1: Stands for adjusted Bonferroni p-value for ANOVA with repeated measures for
comparison between pre with immediate post-program
P2: Stands for adjusted Bonferroni p-value for ANOVA with repeated measures for comparison between pre with six weeks post-program

Table 5: Correlation between self-efficacy and quality of life of the study subjects pre the application, immediately after the application of self-care management
program and six weeks post program
Self-efficacy
-----------------------------------------------------------------------------------------------------------------------------------------------------
Pre-program Immediate post-program Six weeks post-program
----------------------------------- ---------------------------------- --------------------------------
DQ_39_SI sub items X2 MC
p X2 MC
p X2 Mc
p
Mobility 172.812 0.001* 224.617 0.001* 330.234 0.001*
ADLs 135.758 0.001* 140.855 0.001* 230.162 0.001*
Emotional wellbeing 167.964 0.131 67.196 0.015* 134.302 0.011*
Stigma 144.323 0.007* 78.024 0.048* 131.681 0.085
Social support 92.893 0.198 74.517 0.165 103.597 0.042*
Cognition 125.557 0.033* 74.601 0.046* 160.832 0.013*
Communication 118.135 0.001* 54.696 0.024* 104.481 0.007*
Bodily discomfort 105.191 0.162 32.960 0.082 111.967 0.256
PDQ_39_SI TOTAL Score 251.334 0.002* 240.107 ?0.001* 390.646 0.001*
X2: Chi-square test MCp: Monte Carlo P value *Significant P 0.05

but the difference didn't reached to significant level application of the program (21.2±7.2) but the difference
(F= 1.872, P=0.151). After the sixth-week duration, it still didn't reach to the significance level (F=2.102, P= 0.135).
improved if compared to its level prior the program Table (5) reflects that there was an observed
application (59.4±19.2) and the difference became significant correlation between self-efficacy of the study
statistically significant (F= 2.816, P= 0.047*). subjects and their quality of life immediately after the
Before the application of the program, feeling application of self-care management program. This was in
stigmatized among geriatric patients with Parkinson's relation to mobility, activities of daily livings, emotional
disease was (58.5±15.5) which significantly improved well-being, stigma, cognition and communication; the chi
immediately after the program and after six weeks square was (224.617, 140.855, 67.196, 78.024, 74.601, 54.696
(40.9±13.2, 45.4±14.0 respectively) as well as proved to be respectively) and P value was (<0.001*, <0.001*, 0.015*,
significant (F= 3.001, P= 0.040*, F= 4.455, P=0.009* 0.048*, 0.046*, 0.024 respectively).
respectively). This is followed by emotional well-being; The table also portrayed that there was a significant
which improved immediately after the program and after correlation between self-efficacy of the study subjects
the period of six weeks follow up (40.3±14.5, 48.1±17.3 and their quality of life after six weeks from the end of the
respectively) if compared to its level before (59.3±17.6) program. This was regarding mobility, activities of daily
with no statistically significant difference (F= 0.864, livings, emotional well-being, social support, cognition
P= 0.595, F= 1.116, P=0.435 respectively). and communication; the chi square was (330.234, 230.162,
Table (4) reveals that there was an observed 134.302, 103.597, 160.832, 104.481respectively) and P value
improvement in self-efficacy of geriatric patient with was (0.001*, 0.001*, 0.011*, 0.042*, 0.13*, 0.007*
Parkinson's disease along all levels of the program respectively).
evaluation. Immediately after the application, high level of On the other hand, it was observed that there was no
self-efficacy was reported (30.6±5.7) in comparison to its significant correlation founded between self-efficacy of
level pre- the application (21.2±7.2) with a statistical the study subjects and their bodily discomfort either
significant difference (F= 3.376, P=0.038*). Moreover, six immediately after the application of the program or six
weeks post program, self-efficacy of the study subjects weeks post program; (X2 = 32.960, 0.082 respectively), (P=
(29.1±5.7) was still higher than its level prior the 111.967, 0.256 respectively).

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World J. Nursing Sci., 3S: 56-72, 2014

DISCUSSION over two times greater in PD patients who also had 1.3
times more outpatient visits than their non -PD
The current trends in the health care arena behoove counterparts [26]. PD patients had higher levels of costly
self-care management to take a more proactive role in comorbidities. 50% of them as revealed in this study
preservation of function and quality of life (QOL), health reported health disorders with the greatest prevalence
promotion, complications prevention and rehabilitation; of cardiovascular problems and diabetes mellitus.
areas ultimately critical in illnesses of late life onset and This finding is congruent with result of previous study
extended years of disability. One such illness, Parkinson’s which stated that these diseases in addition to
disease (PD), has been associated with decreased quality depression, falls and dementia were determinants of
of life, reduction of functional capacity, depression and higher medical costs among PD beneficiaries.
difficulty in communication, deprived recreation and To the best of our knowledge, the present study is
restrictions in intimate and social life. PD touches all the first in Egypt to directly focus on a relationship
aspects of a person’s life and certainly can have a between QOL and self-efficacy in PD and to develop a
negative impact on the person’s QOL. Consequently, it is comprehensive educational Arabic-version material
worthwhile to investigate QOL issues related to PD and teaching the concept of self-care to those patients and
apply a multidimensional approach to disease later determining the effect self-care interventions posed
management which addresses all aspects of the disease on inducing their self-confidence and impacted on
process to promote QOL of patients involved with this different domains of their lives. The educational material
chronic disease [22]. covered: all physical difficulties PD patients faced and its
Results of the present study revealed that the related self-care interventions and coping strategies;
percentage of geriatric patients with PD was more in the psychological and cognitive complaints and
age group 60 years to less than 65 years than those who demonstrated self-care measures; and other social and
are in the other two age groups. This result doesn’t recreational withdrawal activities; for its; appropriate
contradict literatures that PD increased in incidence with actions would be taken according to the patient individual
advanced age; but the fact that as motor impairment differences in capabilities level. The educational material
intensify, patients display increasing dependence on gave a solution for every smallest common bothersome
others for most aspects of basic self-care with increased problem by simply identifying the suffering, probable
age category, which enforced family members came to the causes, specific problem-solving skills and appropriate
clinic to receive routinely prescribed treatment instead of self-taking measures.
patient who just came to the clinic in case of severely The hallmarked finding of the current study indicated
disrupted new evident. In respect to sex, the present that there is an observed and a significant progress in
study revealed that PD is reported by more males than allover domains of the quality of life of Parkinson’s-
females. Literature explained this phenomenon; where diseased older adults directly after the implementation of
smoking, as a risk behavior for the disease, is more among the proposed self-care management strategies. A possible
males. Men had been more directly exposed than women explanation is that; this type of management succeeded in
to toxicant exposure in agriculture and head trauma; in providing a holistic approach of care which first reflected
addition to the neuroprotection role of estrogen for on self-efficacy and later on QOL. Although it may seem
dopamine activity, or female gonadal factors that provide paradoxical, the current study also exhibited a significant
resilience to dopamine loss [23-25]. relation between those concepts where higher perception
PD exists a significant economic burden on PD of QOL was linked with greater trust in self to manage
patients and their families. In the present study, most of arrays of PD symptoms.
PD geriatric patients (90.9%) complained of the absence Indeed, perceived mastery and maintaining personal
of supported health insurance system for them and their control found to override all other factors, including the
income wasn’t sufficient to follow their conditions with impact of physical disability, in predicting PD patients’
private doctors or in specialized hospitals in addition to quality of life. In addition, the skills learnt through our
the high expenses of medication which are the main program acted synergistically to alter attitudes toward
causes of the monthly visits of the outpatient’s clinics. the disease as can’t be managed. Furthermore, the
Similar supporting studies for this results indicated that prolonged period of interaction between the study
the annual health expenditures, costs for prescription partners, the researcher and the environment within which
medications and utilization of health care services were self-care principles accomplished, provided successful

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World J. Nursing Sci., 3S: 56-72, 2014

experiences in managing the disease, making elders The third explanation claimed from the study done by
persuaded to try new strategies within a supportive Martinez-Martin [26] that the non-motor features of PD
and positive environment. Recently, the work of contribute to an ongoing deterioration of independence
Miertová et al. [1], proved such associations and added in activities of daily living, overall functional status and
that PD patient education through self-care program acted QOL.
as a buffer against the disease dilemma. From this point, the role the exercise played in the
Quality of life is a concept applying to the patient’s significant improvement in these previously mentioned
self-evaluation of the impact of his/her disease [27]. domains in the current research is profound with a
A notable finding in this study was that 63.3% of the statistical significant difference. For sure, exercise either
studied patients reported worsened QOL at the initial flexibility or strengthening is an important ingredient of
evaluation. The mechanism proposed by the researchers self-care management, provided clear benefits for PD
that the patients deal with a disease course that is neither patients as it improves the clinical efficacy of levodopa
predictable nor limited to a decline in physical treatment and gait rhythmicity, maintains balance and
functioning. Dealing with the unpredictability of the mobility, delays functional decline and slows the
disease means that persons with PD should deal with the progression of the disease. The researcher in this study
disease on daily basis, existing more emotional and implemented both types of training 3 times weekly for
physical strains. A plethora of studies postulated many three consecutive months, which become the primary
reasons for diminished quality of life in patients with PD, practice before application of any following session. Each
including reduced mobility, falls, motor complications, session was initiated by practicing of 20 minutes-exercise
affective disorders and sleep disorders [8, 28- 30]. to relief rigidity and associated muscle tensions. The
Although of its complexity, many of these aspects go patient compliance with a form of balance-induced
unnoticed in routine clinical assessments, the results that exercise improves the gait abnormalities which could lead
also assumed in the study of Soh et al. [31]. to fall, that reflect positively on the domains of mobility
Chronic comorbidities eventually interfere with the and bodily discomfort with a great associated
ability to conduct daily activities and PD patients thus enhancement.
become increasingly dependent upon others, increase the It could be acceptable that the self-reported
prone to further complications and prevalence of side improvement was decline in the follow up period due to
effects from polypharmacy [27]. In the present study, lack of appropriate supervision and motivation which may
cardiovascular drugs and hypoglycemic agents are the lead to non-compliance. A very recent study in Jordan
most common consumed prescribed drugs besides (2014) recommended the importance of continuous
antiparkinsonian agents. Analgesics and laxatives are the reinforcement for PD patients to change their perception
most common over the counter drugs consumed by the toward exercising and improve their practices [32].
subjects without prescription for the believe of relieve Although motor impairments are the most prominent
both motor (rigidity) and non-motor (pain and chronic feature of PD and surely affect their ability to carry out
constipation) dysfunction commonly experienced by the daily tasks independently, the cognitive impairments
patients. associated with PD are also likely to have a significant
This is more explained by the current study results impact on independent functioning and performance on
which reflected that mobility (71.25±14.6), body ADLs skills [33]. A significant finding of the present
discomforts (69.7±18.10) and impaired daily activities study was that although PD patients with severe
(59.8±14.8) are among the most impaired domains of QOL. cognitive disturbance were excluded, 60.5% of patients
This is an expected result, as PD is basically diagnosed reported decline in cognition.
with the associated features of impaired mobility The fact is that we can’t separate one domain from
originated from a neurological deficiency of regulated the other. In essence, because PD patients have a
dopamine. As disease progresses, motor impairments perception in impairments in both ADL and motor
intensify and patients display increasing dependence on domains, they have multiple potential contributions to
physical assistance for most aspects of basic self-care, cognitive dysfunction; suggesting a complex relationship
that is why 50.0% of currently studied PD patients used exists between cognitive, motor functioning and
assistive mobility devices. Secondly, those patients performance on ADLs. Medication-induced cognitive and
didn’t follow any form of physical exercising besides the motor changes may not always occur in parallel. That is,
age-related changes in mobility they are often exposed to. administration of levodopa can result in improvement in

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World J. Nursing Sci., 3S: 56-72, 2014

motor functioning and decline in selective components of types of bodily discomfort especially dystonia, muscle
cognitive processing. Thus, it would be possible to see cramps and headache through medication adjustment,
dissociable changes in cognition and ADL performance sensory tricks, stretching exercises, being more active and
depending on drug dosage and time of administration. or move around strategies.
with mild cognitive impairment to follow the instructions A suggested link between PD-related cognitive
taught in the interventional In this regard, it is notable to decline, dependence and a host of PD psychological
mention that all current studied participants follow some comorbidities such as depression, apathy, anxiety and
form of dopaminergic prescription, supporting the hallucinations, was proved evidence. This assumption
previous phenomena meaning that the acute and finding substantially supported in the present study
short-term changes in cognition may be drug related as where, in addition to impaired physical and cognitive
the recruited PD patients in this study selected to be domains, poor emotional wellbeing was prevalent among
cognitively intact program. 59.3% of the studied elders.
Broeders et al. [34] and Leroi et al. [35] stated that Cubo et al. [39] determined that psychological
even mild cognitive impairment which were prevalent factors affected quality of life of PD patients more than
among 15%-40% of PD patients, can lead to poor QOL. physical factors did. Alternately, Prediger et al. [40]
Through self-care training for managing the cognitive suggested that the effects of the disease prevent patients
decline, the studied participants in the current study from using their customary coping strategies, which
showed an observed improvement due to cognitive increases anxiety and provokes tremors. Depression and
training or cognitive stimulation interventions. Examples PD share overlapping symptoms in old age such as
are visual prompts (calendars, clocks, notice boards and reduced facial expression, problems with sleeping, fatigue
notices), promote daily routine and organization, verbal and reduced appetite [41].
strategies and maintain independence through at least These similar symptoms may contribute to the under
hobbies. diagnosis of depression in patients with PD. Moreover,
One of the sound finding of this study is the mild depression is an especially common symptom in the
improvement in the area of pain and general bodily early stages of PD and is associated with increased
discomfort. The most frequently occurring pain types in disabilities and rapid progression of motor symptoms
PD are musculoskeletal and dystonic pain. A prospective [42, 43]. Psychological status improved significantly in the
study by Santos-Garcia et al. [36] including 159 PD present study after application of supported measures, for
patients assessed in a movement disorders unit, found a instance, practice of relaxation techniques, massage and
high prevalence of pain (72.3%). They also determined avoiding triggers of anxious episodes and stimulus for
that this symptom behaved as an independent predictor controlling anxiety. For depression, the program provided
of poorer quality of life. Similarly, bodily discomfort is support group therapy or individual therapy using
prevalent among 69.7% of the studied participants in the cognitive behavioral techniques by teaching new skills to
current research. For several, bodily discomforts are help deal with negative thoughts and problems more
frequent complaints during the course of the illness and effectively. Techniques used include relaxation,
often under-recognized and inadequately treated by the distraction and goal setting through a weekly session.
health care professionals. Social support buffered the adverse effects of
Pain originates from dopamine depletion and the stressful life events. Thus, an effective social support
development of Lewy pathology leading to frozen, network can provide opportunities for positive feedback
cog-wheel type of resistance and led pipe-like phenomena and managing uncomfortable feelings [44]. Of special
characterized the disease process that is responsible for relevance to the present study, impaired social support
restricted mobility or dyskinesia and disability performing and communication were reported by 59.4% of the current
day to day tasks [37]. This type of discomfort sensations studied patients. Impaired facial emotion identified in PD
were more reported in patients with motor- dominant appears to be correlated with a variety of interpersonal
subtype than in those with the tremor- dominant one [38]. difficulties such as complaints of frustration in social
In the current study; although the degree of improvement relations and feelings of social disconnection.
in discomfort doesn’t reach to be statistically significance, In this respect, Soleimani et al. [45] mentioned that
there is a reduction of mean percent score immediately PD imposed limitations on patients’ ability to
after the interventions and in the follow- up weeks. As so, communicate with others and were cognizant of their
self-care management implemented relieved different distractibility and difficulty with word-finding and

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World J. Nursing Sci., 3S: 56-72, 2014

thought processing while engaging in communication, treatment plans for older adults. The most recent trends in
which influenced their decision to participate or not in PD self-care management program involve working
conversation. On this basis, PD patients’ perceptions simultaneously with the patients and his family and
regarding their voices conveyed concern about the modify the environment through which the program takes
decreased strength of voice; deterioration in its quality, place.
rate and clarity; and difficulty with initiating speech
movements. As a consequence of their speech and CONCLUSION
communication difficulties, PD patients experience loss of
self-esteem, loss of dignity and altered socialization The findings confirmed the hypotheses of the current
processes ranging from apprehension, disengagement, to study. The application of self-care strategies is elegantly
complete withdrawal. effective in upgrading the quality of life of geriatric
Speech and language therapy, social support group, patients with Parkinson's disease and help in improvement
use identification cards and practical tips to improve of their self-efficacy with an observed statistically
writing are ways of self-care taught to those patients with differences among the two studied constructs prior and
social and communication difficulties in the current study. immediately after the program. This improvement regretted
By far, Hammarlund and colleges [46] described the over time but still better than before.
efficacy of such interventions on QOL of PD patients in In the light of these results, the authors highlighted
their study. the following recommendations:
People with PD experience shame and embarrassment
as a consequence of PD symptoms and / or perceived The importance of evaluating quality of life and
reactions from others (presented by 58.5% of the current self-efficacy as a part of the clinical comprehensive
studied patients). Avoidance of social situations; avoid assessment for patients with PD. The identification
eating, drinking and writing in public due to tremor and of any deficits should be used as a rational basis for
feel embarrassed made them consequently withdraw from guiding self-care management programs about
society [11]. Feeling of stigmatization in PD derived from provide systematic multidisciplinary approach for
many factors. First is the common belief that PD is a assessing the efficacy of combined pharmacological,
disease only for older adults; second is linked to patient’s behavioral, occupational, physical and surgical
perception to be a burden for caregivers; third arises from interventions for the relief of PD symptoms.
the uncertain progression of the disease. In-service training program should be planned and
The contribution of PD to the stigma perception also offered periodically to nurses who deal with PD
back to the undesirable self-image, loss of autonomy, geriatric patients in order to update their knowledge
inability to perform not only usual work activities but also and improve their skills about self-care management.
simple motor actions, feelings of frustration and Then after, these types of interventions should be
neglecting linked to withdrawal and communication incorporated into the routine nursing practice for
changes in the form of voice and articulation changes in those patients and their involved careers; for the
addition to attention difficulties. These factors go on line reason of enhancing patients' quality of life and
with the work of Burgener and Berger [47]. Changes consequently their self-efficacy.
developed and perceived in the other domains of QOL Educational materials in the form of printed handouts
through the program in the current study, explained the and colored brochures should be provided to the PD
observed improvement in patient feeling of stigmatization geriatric patients and their caregivers in order to help
toward himself due to the disease progressive and them following the principles of self-care strategies.
complicated process, through expelling out of myths The allocation of additional resources to patient
and stereotypes, changing attitudes and practicing of management should be targeted in this disease and
self-help. lack of appropriate rehabilitation centers in Egypt
In sum, attention to quality of life features is critical with qualified and specialized therapists specific for
to the management of PD which should be a those patients, should be overcome.
multidisciplinary approach, includes a coordination of Focused exercises program should be planned and
pharmacological and non-pharmacological treatment. conducted to geriatric patients with Parkinson's
Currently, gerontological nurses are the staunchest disease, this help them in obtaining the optimal level
proponents of integrating self-care management into of mobility within their limited functional abilities.

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ACKNOWLEDGEMENT 9. Gómez-Esteban, J. and B. Tijero, 2007. Influence of


Motor Symptoms upon the Quality of Life of Patients
The authors are thankful to all elders willing agreed with Parkinson’s Disease. European Neurology.
to participate in this study. Deepest gratitude also goes Available at: https://www.researchgate.net/
to the manger of neuropsychiatric outpatient clinic of publication/6587191 Retrieved on 7-8-2014.
El-Hadara orthopedic and traumatology University 10. Bikmullina, R. and Z. Vilpponen, 2013. Patient
Hospital who willing allowed to conducting the study Education Among Patients with Parkinson’s Disease.
there. Published Master Thesis. Degree Program in
Nursing, Helsinki Metropolia University of Applied
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