SPOREFORMING AEROBIC GRAM POSITIVE BACILLI- Bacillus spp.

`` Bacillus Bacillus Bacillus

anthracis cereus thuringiensis
Spore is oval and doesn’t distend the Chinese restaurant syndrome Used as larvicide
cell, centrally located Self limiting disease
Description Large bacilli
Straight rod with right angle end
Occurs in singly/pairs
Contaminated blood and tissues of Environment- farm animals
Source animals (esp.poultry)

Antigenic capsule Enterotoxin DNA plasmid with protein

Plasmid encoded pXO2 Glycoprotein s-layer
Virulence Factor Anthrax toxin/Exotoxin:
protective Ag
Edema factor
Lethal factor
5% BAP: irregular fringe like edge
Culture “MEDUSA HEAD MORPHOLOGY”
Bicarbonate agar: capsule production

Cutaneous anthrax: eschar (dark Food poisoning

Pathogenesis pustule), edema Gastroenteritis
Pulmonary anthrax: massive enlarged ophthalmitis
mediastinal lymph nodes
Skin contact: malignant pustule Ingestion of contaminated food
Transmission Ingestion of contaminated food:
gastroenteritis
Inhalation of contaminated dust:
woolsorter’s disease
Agar with bacteriophage, mouse
Lab Dx inoculation, ELISA