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Module: ASA Monitoring Standards and ASA

Sedation Guidelines
Slides (3-11)

Monitoring Standards and Sedation


• It is important to distinguish between
“monitored anesthesia care” and
“sedation/analgesia”
ANESTHESIA PROCEDURES, METHODS,
• In October 2004, the American Society of
& TECHNIQUES IV
Anesthesiologists (ASA) approved:
Jerrold Lerman, MD • Sedation/ analgesia is the term currently used
Clinical Professor of Anesthesiology by the ASA in their recently published Practice
John R. Oishei Children’s Hospital, Guidelines for Sedation and Analgesia by Non-
Jacobs School of Medicine and Biomedical Anesthesiologists
Sciences, • Monitored anesthesia care implies the potential
Buffalo, NY for a deeper level of sedation than that
jerrold.lerman@gmail.com provided by sedation/analgesia and is always
administered by an anesthesiologist provider
The standards for preoperative evaluation,
Question Based Learning
intraoperative monitoring, and the continuous
Lecture Modules presence of a member of the anesthesia care
team, and so forth, are no different from those
• American Society of Anesthesiologists (ASA)
for general or regional anesthesia
Monitoring Standards and ASA Sedation
ASA position statement that defines monitored
Guidelines
anesthesia care as follows
• Selected Complications of Anesthesia
• Monitored anesthesia care is a specific
anesthesia service for a diagnostic or
therapeutic procedure. Indications for
monitored anesthesia care include the nature
of the procedure, the patient's clinical
condition, and/or the potential need to convert
to a general or regional anesthetic
• Monitored anesthesia care includes all aspects
of anesthesia care, the anesthesiologist
provides or medically directs a number of
specific services
– Diagnosis and treatment of clinical problems
– Support of vital functions
– Administration of all medications needed
– Psychological support and physical comfort
– Provision of other medical services as needed
to complete the procedure safely

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Monitoring Standards and Sedation cont’d Monitoring Standards and Sedation cont’d
ASA position statement that defines monitored • Because of the significant risk that patients who
anesthesia care as follows cont’d receive deep sedation may enter a state of
• Monitored anesthesia care may include varying general anesthesia, privileges to administer
levels of sedation, analgesia, and anxiolysis as deep sedation should be granted only to
necessary. The provider may have to convert to practitioners who are qualified to administer
general anesthesia. If the patient loses general anesthesia or to appropriately
consciousness and the ability to respond supervised anesthesia professionals
purposefully, the anesthesia care is a general
anesthetic, irrespective of whether airway Question: Standard II of the ASA’s Standards for
instrumentation is required basic anesthetic monitoring requires all of the
• Monitored anesthesia care should be subject to following except which one?
the same level of payment as general or A. Physical presence of an anesthesia care
regional anesthesia provider
• ASA states that all institutional regulations B. An oxygen analyzer with a low FiO 2 alarm
pertaining to anesthesia services shall be C. A means for measuring patient
observed, and all the usual services performed temperature
by the anesthesiologist shall be furnished, D. A device to signal disconnection from the
including but not limited to mechanical ventilator
– Usual non-invasive cardiocirculatory and
Monitoring Standards and Sedation
respiratory monitoring
• Standards for basic anesthetic monitoring have
– Oxygen administration, when indicated
been established by the ASA. Since 1986, these
– Administration of sedatives, tranquilizers,
standards have emphasized the importance of
antiemetics, narcotics, other analgesics,
regular and frequent measurements,
beta-blockers, vasopressors, bronchodilators,
integration of clinical judgment and experience,
antihypertensives, or other pharmacologic
and the potential for extenuating circumstances
therapy as may be required in the judgment
that can influence the applicability or accuracy
of the anesthesiologist
of monitoring systems
• Controversy exists regarding the level of
• Standard I requires qualified personnel to be
training required for non-anesthesiologists to
present in the operating room during general
be credentialed to provide moderate and deep
anesthesia, regional anesthesia, and monitored
sedation
anesthesia care to monitor the patient
• The ASA released a statement in October 2005,
continuously and modify anesthesia care based
amended in October 2006, suggesting a
on clinical observations and the responses of
framework for granting privileges that will help
the patient to dynamic changes resulting from
ensure competence of individuals who
surgery or drug therapy
administer or supervise the administration of
• Standard II focuses attention on oxygenation,
moderate sedation
ventilation, circulation, and temperature
• In 2005 and 06, ASA recommended complete
– Using an oxygen analyzer with a
formal training in
low concentration-limit alarm during GA
– (1) the safe administration of sedative and
– Quantitatively assessing blood oxygenation
analgesic drugs used to establish a level of
during any anesthesia care
moderate sedation, and
– Continuously ensuring the adequacy of
– (2) rescue of patients who exhibit adverse
ventilation by physical diagnostic techniques
physiologic consequences of a deeper-than-
during all anesthesia care. Identification of
intended level of sedation
expired carbon dioxide is performed unless
nullified by the type of patient, procedure, or
equipment

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Monitoring Standards and Sedation cont’d
– Quantitative monitoring of tidal volume and Module: Selected Complications of
capnography is strongly encouraged in Anesthesia
patients undergoing general anesthesia Slides (12-45)
– When administering regional anesthesia or
monitored anesthesia care, Question: Which of the following would produce
sufficient ventilation should be assessed by the worst impact on the ability to spontaneously
qualitative clinical signs and/or monitoring of ventilate?
exhaled carbon dioxide A. Bilateral sentinel lymph node (SLN) injury
– Ensuring correct placement of a tracheal B. Unilateral Recurrent laryngeal nerve
tube or laryngeal mask airway (LMA) requires (RLN) injury
clinical assessment and qualitative C. Bilateral RLN injury
identification of carbon dioxide in the expired D. Bilateral Vagus nerve injury
gas. During general anesthesia, capnography
Airway Injury
and end-tidal carbon dioxide analysis is
• Unilateral denervation of a cricothyroid muscle
performed
causes very subtle clinical findings
– When using a mechanical ventilator, there
• Bilateral palsy of the SLN may result
should be a device that is able to detect
in hoarseness or easy tiring of the voice, but
a disconnection of any part of the breathing
airway control is not jeopardized
system
• Bilateral injury to the vagus nerve affects both
– The adequacy of circulation should be
the superior and the recurrent laryngeal nerves.
monitored by the continuous display of
Thus, bilateral vagal denervation
the EKG, and by determining the
produces flaccid, midpositioned vocal cords
arterial blood pressure and heart rate at least
similar to those seen after administration of
at 5 min intervals. During general anesthesia,
succinylcholine. Although phonation is severely
circulatory function is to be continually
impaired in these patients, airway control
evaluated by the quality of the pulse, either
is rarely a problem
electronically or by palpation or auscultation
• Unilateral paralysis of a RLN results in paralysis
– During all anesthetics, the means for
of the ipsilateral VC, causing a deterioration in
continuously measuring the
voice quality
patient's temperature must be available.
• Acute bilateral recurrent laryngeal nerve palsy
When changes in body temperature are
can result in stridor and respiratory distress
intended or anticipated, temperature should
because of the remaining unopposed tension
be continuously measured and recorded on
of the cricothyroid muscles
the anesthesia record
• Airway problems are less frequent
in chronic bilateral recurrent laryngeal nerve
loss because of the development of
various compensatory mechanisms (e.g.,
atrophy of the laryngeal musculature)

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Airway Injury cont’d

Anterior Ethmoid N
Sphenopalatine N
(V1)
(V2)

Lingual N
(V3)
CN 9

SLN (Int)

RLN

Question: Compared with high-pressure/low- Airway


volume cuffs, endotracheal tubes (ETTs) with • There are two major types of cuffs: high
low-pressure/high volume cuffs are more likely pressure (low volume) and low pressure (high
to cause all of the following except which one? volume)
A. Passive aspiration • High-pressure cuffs are associated with
B. Sore throat more ischemic damage to the tracheal mucosa
C. Mucosal damage and are less suitable for intubations of long
D. Spontaneous extubation duration
• Low-pressure cuffs may increase the likelihood
of sore throat (larger mucosal contact
area), aspiration, spontaneous extubation,
and difficult insertion (because of the floppy
cuff)

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Airway Question: Which of the following patients is
TRUE or FALSE LEAST likely to exhibit a decrease in body
• Laryngeal trauma is more likely to occur during temperature?
routine (non-difficult) tracheal intubation A. A patient in spontaneous labor receiving
compared with difficult laryngoscopies epidural anesthesia for 8 hr
TRUE B. A patient undergoing a appendectomy
• The ASA Closed Claims Database reveals that under general anesthesia for 1 hr
claims for laryngeal injury during DL arise more C. A patient undergoing abdominoplasty
often in “easy” as opposed to difficult under monitored anesthesia care for 1 hr
laryngoscopies D. A patient undergoing spinal anesthesia
• In the ASA Closed Claim Database, 87 instances for a 30 min knee arthroscopy
of laryngeal trauma were recorded (out of 4460
cases). Of these, 80% occurred during routine Hypothermia
(easy) tracheal intubation, in which no injury • Hyperthermia frequently complicates epidural
was suspected analgesia for labor and delivery
– It is more likely during prolonged labor (i.e.,
Question: During deliberate hypothermia, >8 hrs)
temperature measurement at which of the –  Body temperature in laboring and
following sites will MOST likely lag behind the postoperative patients is presumably true
true core body temperature? fever (i.e., a regulated increase in core
A. Middle ear temperature) resulting from infection or
B. Esophagus inflammation
C. Bladder – The conventional assumption is that
D. Nasopharynx hyperthermia is caused by the technique,
although no convincing mechanism has been
Hypothermia
proposed
• Both general and regional anesthesia inhibit
• It is worth remembering, though, that pain
afferent and efferent control of
in “control” patients is usually treated with
thermoregulation
opioids—which themselves attenuate
• Heat losses may result from radiation,
fever. Fever associated with infection or
convection, evaporation, and conduction,
tissue injury might then be suppressed by
– Radiation refers to the infrared rays
the low doses of opioids that are usually
emanating from all objects above absolute
given to the “control” patients while being
temperature
expressed normally in patients given
– Convection refers to the transfer of heat
epidural analgesia The extent to which this
from air passing by objects
mechanism contributes remains to be
– Evaporation represents the heat loss that
determined and has been disputed, but no
results when water vaporizes
convincing alternative explanation has
– Conduction refers to the transfer of heat
been advanced
from contact with objects
• Even during cardiopulmonary bypass, the core
• Perioperative hypothermia predisposes patients
temperature–monitoring sites (e.g., tympanic
to  in metabolic rate (shivering) and cardiac
membrane, nasopharynx, pulmonary artery,
work,  in drug metabolism and cutaneous
and esophagus) remain useful
blood flow, and impairs coagulation
• In contrast, rectal temperatures lag behind
those measured in core sites. Consequently,
rectal temperature is considered an
“intermediate” temperature in deliberately

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cooled patients during anesthesia

Hypothermia cont’d Ocular Complications


• During cardiac surgery, bladder temperature is • Therefore, it may be prudent to tape the eyelids
equal to rectal temperature (and therefore closed immediately after induction, and during
intermediate) when urine flow is low, but it is mask ventilation and laryngoscopy
equal to pulmonary artery temperature (and • In addition to taping the eyelids closed,
thus core) when flow is high applying protective goggles and instilling
– Because bladder temperature is strongly petroleum-based ointments into the
influenced by urine flow, it may be difficult to conjunctival sac may provide protection
interpret in these patients. Adequacy of – Disadvantages of ointments include
rewarming is best evaluated by considering occasional allergic reactions
both “core” and “intermediate” – Flammability, which may make their use
temperatures undesirable during surgery around the face
• Core temperature usually decreases 0.5°C to and contraindicated during laser surgery and
1.5°C in the first 30 mins after induction of blurred vision in the early postoperative
anesthesia period
• Core temperature perturbations during the first – The blurring and foreign-body sensation
30 mins of anesthesia are thus difficult to associated with ointments may
interpret, and measurements are not usually actually increase the incidence of
required postoperative corneal abrasions if they
• Body temperature should, however, be trigger excessive rubbing of the eyes while
monitored in patients undergoing general the patient is still emerging from anesthesia
anesthesia exceeding 30 mins in duration and in • Patients with corneal abrasion usually complain
all patients whose surgery lasts longer than 1 hr of a foreign-body sensation, pain, tearing, and
• The ASA standards require only that “every photophobia
patient receiving anesthesia shall have • The pain is typically exacerbated by blinking and
temperature monitored when clinically ocular movement
significant changes in body temperature are • It is wise to have an ophthalmologic
intended, anticipated, or suspected.” For office- consultation immediately
based sedation, regional anesthesia, or general • Treatment typically consists of the prophylactic
anesthesia, the ASA also requires that “the application of antibiotic ointment and patching
body temperature of pediatric patient shall be the injured eye shut
measured continuously” • Although permanent sequelae are possible,
healing usually occurs within 24 hr
Ocular Complications • Because of a perceived increase in the
• The most common ocular complication of incidence of postoperative visual loss since the
general anesthesia is corneal abrasion mid-1990s, the Committee on Professional
• A variety of mechanisms can result in corneal Liability of the ASA established the
abrasion, including Postoperative Visual Loss Database on July 1,
– Damage caused by the anesthetic mask 1999, to better identify associated risk factors
– Surgical drapes, and spillage of solutions so these tragic complications might be
– During intubation of the trachea, the end of prevented in the future
plastic watch bands or hospital identification • The incidence of postoperative vision loss after
cards clipped to the laryngoscopist's vest spine surgery in the prone position (posterior
pocket can injure the cornea ischemic optic neuropathy) up to 1%: assoc’d
– Ocular injury may also occur from loss of pain with males, hypotension, anemia, >6 h surgery,
sensation, obtundation of protective corneal increased venous/eyeball pressure, less colloids
reflexes, and decreased tear production
Source: Goepfert CE, et al. Curr Opin Anaesth 2010:23;582.

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likely, compression of the pial vessels

Ocular Complications Ocular Complications cont’d


• Although the multifactorial pathophysiology – Typical findings include an afferent pupillary
of anterior ischemic optic neuropathy has not defect or nonreactive pupil. Disc edema is
been completely established, it is believed to not a feature of posterior ischemic optic
involve temporary hypoperfusion or non- neuropathy because of its retro-orbital
perfusion of the vessels supplying the anterior position. CT scan in the early postoperative
portion of the optic period may reveal enlargement of the
– Coexisting systemic disease, especially intraorbital portion of the optic nerve.
involving the cardiovascular system and (to a Bilateral blindness is more common with
lesser extent) the endocrine system, is posterior ischemic optic neuropathy than
common in patients in whom anterior with anterior ischemic optic neuropathy,
ischemic optic neuropathy develops. Male possibly indicating involvement of the optic
gender also strongly predominates. Other chiasm
risk factors for postoperative anterior – A review of the first 6 yrs of cases submitted
ischemic optic neuropathy include coronary to the ASA Postoperative Visual Loss Registry
artery bypass graft (CABG) and other found that spine surgery patients at greatest
thoracovascular operations, as well as spinal risk for ischemic optic neuropathy and visual
surgery compromise include those with predisposing
– Other possible risk factors are increased patient-specific factors, surgery exceeding 6
intraocular pressure (IOP) or orbital venous hrs.’ duration, and blood loss of more than a
pressure. Anterior ischemic optic neuropathy liter
is not usually caused by emboli because
emboli preferentially lodge in the central Question: Which of the following statements
retinal artery rather than in the short regarding ulnar neuropathy (UN) is considered
posterior ciliary arteries that supply the false?
anterior optic nerve A. High body mass index (BMI) is a risk factor
– Pts typically have painless visual loss that for UN
may not be noted until the first B. There exists a high frequency of patients
postoperative day (or possibly later), an who complain of UN that have
afferent pupillary defect, and optic disc contralateral ulnar nerve conduction
edema or pallor. MRI or CT initially shows deficits
enlargement of the optic nerve C. The majority of complaints of UN will
– Therapy includes intravenous acetazolamide, occur in the first 12 postoperative hr
furosemide, mannitol, and steroids D. Prevalence in men greater than women
• The posterior optic nerve has a less luxuriant
blood supply than the anterior optic nerve
– In contrast to anterior ischemic optic
neuropathy, relatively few cases have been
reported after CABG, and posterior ischemic
optic neuropathy appears to be less related
to coexisting cardiovascular disease. As with
anterior ischemic optic neuropathy, male
patients outnumber female patients four to
one
– Posterior ischemic optic neuropathy is
produced by reduced oxygen delivery to the
retrolaminar part of the optic nerve. Most

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References for Difficult Intubation
Ulnar Neuropathy
• Shiga T, Wajima Z, Inoue T et al: Predicting
• Typically, anesthesia-related ulnar nerve injury
Difficult Intubation in Apparently Normal
is thought to be associated with external nerve
Patients: A Meta-analysis of Bedside Screening
compression caused by malpositioning.
Test Performance. Anesthesiology 2005; 103:
Although this implication may be true for some
429.
patients, three findings suggest that other
• El-Ganzouri AR, McCarthy RJ, Tuman KJ et al:
factors may contribute
Preoperative airway assessment: predictive
– First, patient characteristics (e.g., male sex,
value of a multivariate risk index. Anesth Analg
high body mass index [>38], and prolonged
1996; 82: 1197.
postoperative bed rest) are associated with
• Wilson ME, Spiegelhalter D, Robertson J et al:
these ulnar neuropathies. Various reports
Predicting difficult intubation. Br J Anaesth
suggest that 70% to 90% of patients who
1988; 61: 211.
have this problem are men
• Naguib M, Malabarey T, AlSatli RA et al:
– Second, many patients with perioperative
Predictive models for difficult laryngoscopy. A
ulnar neuropathies have a high frequency of
clinical, radiologic and three dimensional
contralateral ulnar nerve conduction
computer imaging study. Can J Anesth 1999; 46:
dysfunction. This finding suggests that many
748.
of these patients likely have asymptomatic
• American Society of Anesthesiologists Task
but abnormal ulnar nerves before their
Force on Management of the Difficult
anesthetics, and these abnormal nerves may
Airway: Practice guidelines for management of
become symptomatic during the
the difficult
perioperative period
airway. Anesthesiology 2003; 98:1269-1277.An
– Finally, many patients do not notice or
updated report by the American Society of
complain of ulnar nerve symptoms until >48
Anesthesiologists Task Force on Management
hrs after their surgical procedures. A
of the Difficult Airway.
prospective study of ulnar neuropathy in
• Karkouti K, Rose DK, Wigglesworth D, Cohen
1,502 surgical patients found that none
MM: Predicting difficult intubation: A
of the patients had symptoms of the
multivariable analysis. Can J
neuropathy during the first 2 postoperative
Anaesth 2000; 47:730-739.
days
• Rosenstock C, Gillesberg I, Gatke MR, et
• Why are men more likely to have this
al: Inter-observer agreement of tests used for
complication?
prediction of difficult laryngoscopy/tracheal
– First, two anatomic differences may increase
intubation. Acta Anaesthesiol
the chance of ulnar nerve compression in the
Scand 2005; 49:1057-1062.
region of the elbow. The tubercle of the
• Rose DK, Cohen MM: The airway: Problems and
coronoid process is approximately 1.5 times
predictions in 18,500 patients. Can J
larger in men than women. In addition, there
Anaesth 1994; 41:372-383.
is less adipose tissue over the medial aspect
• Lee A, Fan LT, Gin T, et al: A systematic review
of the elbow of men compared with women
(meta-analysis) of the accuracy of the
of similar body fat composition
Mallampati tests to predict the difficult
– Second, men may be more likely to have a
airway. Anesth Analg 2006; 102:1867-1878.
well-developed cubital tunnel retinaculum
than women, and the retinaculum is thicker

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References for Difficult Ventilation
• Langeron O, Masso E, Huraux C et al: Prediction Answer Key
of difficult mask ventilation. Anesthesiology
2000; 92: 1229. Question: Standard II of the ASA’s Standards for
• Kheterpal S, Han R, Tremper KK et al: Incidence basic anesthetic monitoring requires all of the
and predictors of difficult and impossible mask following except which one?
ventilation. Anesthesiology 2006; 105: 885. A. Physical presence of an anesthesia care
provider
References for Preoxygenation B. An oxygen analyzer with a low FiO 2 alarm
• Benumof JL: Preoxygenation: Best method for C. A means for measuring patient
both efficacy and efficiency (editorial). temperature
Anesthesiology 1999; 91: 603. D. A device to signal disconnection from the
• Jense HG, Dubin SA, Silverstein PI et al: Effect of mechanical ventilator
obesity on safe duration of apnea in
anesthetized humans. Anesth Analg 1991; 72: Question: Which of the following would produce
89. the worst impact on the ability to spontaneously
• Baraka AS, Taha SK, Aouad MT et al: ventilate?
Preoxygenation: Comparison of maximal A. Bilateral sentinel lymph node (SLN) injury
breathing and tidal volume breathing B. Unilateral Recurrent laryngeal nerve
techniques. Anesthesiology 1999; 91: 612. (RLN) injury
• Taha SK, Siddik-Sayyid SM, El Khatib MF et al: C. Bilateral RLN injury
Nasopharyngeal oxygen insufflation following D. Bilateral Vagus nerve injury
pre-oxygenation using the four deep breath Question: Compared with high-pressure/low-
technique. Anaesthesia 2006; 61: 427. volume cuffs, endotracheal tubes (ETTs) with
• El-Khatib MF, Kanazi G, Baraka AS: Noninvasive low-pressure/high volume cuffs are more likely
bilevel positive airway pressure for to cause all of the following except which one?
preoxygenation of the critically ill morbidly A. Passive aspiration
obese patient. Can J Anaesth 2007; 54: 744. B. Sore throat
• Dixon BJ, Dixon JB, Carden JR et al: C. Mucosal damage
Preoxygenation is more effective in the 25 D. Spontaneous extubation
degrees head-up position than in the supine
position in severely obese patients: a Question: During deliberate hypothermia,
randomized controlled study. Anesthesiology temperature measurement at which of the
2005; 102: 1110. following sites will MOST likely lag behind the
• Baraka AS, Hanna MT, Jabbour SI et al: true core body temperature?
Preoxygenation of pregnant and nonpregnant A. Middle ear
women in the head-up versus supine position. B. Esophagus
Anesth Analg 1992; 75: 757. C. Bladder
D. Nasopharynx

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Question: Which of the following patients is
LEAST likely to exhibit a decrease in body
temperature?
A. A patient in spontaneous labor receiving
epidural anesthesia for 8 hr
B. A patient undergoing an appendectomy
under general anesthesia for 1 hr
C. A patient undergoing abdominoplasty
under monitored anesthesia care for 1 hr
D. A patient undergoing spinal anesthesia
for a 30 min knee arthroscopy

Question: Which of the following statements


regarding ulnar neuropathy (UN) is considered
false?
A. High body mass index (BMI) is a risk factor
for UN
B. There exists a high frequency of patients
who complain of UN that have
contralateral ulnar nerve conduction
deficits
C. The majority of complaints of UN will
occur in the first 12 postoperative hr
D. Prevalence in men greater than women

End of Lecture

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Anesthesiology: Anesthesia Procedures, Methods, & Techniques IV


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