Q blood histology

1- Poikilocytosis is:
a. Abnormal RBC size
b. Abnormal RBC shape
c. Defective elasticity of RBC
d. Defective hemoglobin

2- Blood film is stained with:

a- H&E
b- Silver
c- Leishman stain
d- PAS

3- Inner aspect of the RBC is related to:

a- Glycoproteins
b- Antigens determining blood groups
c- Ankyrin & spectrin
d- glcophorin

4- responsible for flexibility of RBCs

a- spectrin lattice ‫شبكه‬
b- glycophorine
c- glycocalyx
d- band 3 priotein

5- in 2nd trimester, blood is formed in:

a. yolk sac
b. mesoblastic phase
c. hepatosplenothimic phase
d. myeloid phase

6- the following are stem cells except:

a. PHSC
b. Myeloid sc
c. Lymphoid sc
d. CFU-E
7- Fixed cells of bone marrow include the following except:
a. Reticular cells
b. Reticulocyte
c. Fat cells
d. Stem cells

8- First step in erythropoiesis to be released in blood is:

a. Reticular cell
b. Normoblast
c. Reticulocyte
d. Erythrocyte

9- Reticulocytes are supravitally stained with:

a. PAS
b. H&E
c. Leishman
d. Cresyl blue

10- RBCs in hypertonic solution undergoes:

a. Spherocytosis
b. Crenation
c. Rouleaux formation
d. Hemolysis

11- α (alpha) granules in platelets contain the following except:

a. platelet factor 4,
b. fibrinogen
c. platelets-derived growth factors
d. serotonin
12- delta granules of platelets contain the following except:
a. ATP
b. ADP
c. Serotonin
d. Fibrinogen

13- Endomytosis occur in which stage of platelets formation:

a- Megakaryocyte
b- Megakaryoblast
c- CFU-M
d- Mature platelets

14- Microtubule rings of platelets, all true except:

a. Formed of microtubules
b. Present in hyalomere
c. Preserve discoid shape of platelets
d. Concerned with Ca ion release

15- Which of the following facilitate rapid elongation of megakaryocyte

processes during platelets formation:
a. Microtubule rings
b. Open tubular system
c. Alpha granules
d. Demarcation membrane superficial invaginations

16- Blood cells origin :

a. Endodermal
b. Ectodermal
c. Mesodermal
d. Surface ectoderm
17- Energy requirements of RBCs come from:
a. Mitochondria
b. Fatty acid oxidation
c. Enzymes for glycolysis & Hexose monophosphate shunt
d. Stored ATP

18- Multipotent hemopoietic stem cells:

a. Differentiate into pluripotent stem cells
b. Are of 2 types myeloid & lymphoid
c. Have highest capacity for self renewal
d. Reached terminal differentiation

19- Anisocytosis:
a. Variable RBC shape
b. Variable RBC size
c. Variable hemoglobin content
d. Variable RBC life span

20- megakaryoblst originate from:

a. Multipotent lymphoid stem cell
b. CFU-E
c. CFU-M
d. CFU-L

21- The biconcave disc of RBCs is due to:

a. Lack nucleus.
b. Lack organelles.
c. Cytoskeleton protein on inner surface of cell membrane.
d. Glycocalyx on outer surface of cell membrane.

22- The platelet contains microtubules and actin filaments which present in:
a. Peripheral zone.
b. Central zone.
c. Its membranes.
d. Whole cytoplasm.
23- Which type of platelet granules contains hydrolytic enzymes?
a. Alpha.
b. Delta.
c. Lambda.
d. Beta.

24- During erythropoiesis hemoglobin begins to accumulate in:

a. Normoblasts. 1. B
b. Proerythroblasts. 2. C
c. Basophil erythroblasts. 3. C
d. Polychromatophilic erythroblasts. 4. A
5. C
6. D
7. B
8. C
9. D
10. B
11. D
12. D
13. B
14. D
15. D
16. C
17. C
18. B
19. B
20. C
21. C
22. A
23. C
24. d