Hereditary Angioedema Treatment Market: Introduction

 Transparency Market Research has published a new report on the hereditary

angioedema treatment market for the forecast period of 2019–2027. According to the
report, the global hereditary angioedema treatment market was valued at ~US$ 2 Bn in
2018, and is projected to expand at a CAGR of ~9% from 2019 to 2027.
 Hereditary angioedema is an autosomal disorder, wherein, the level of functional C1
esterase inhibitor protein is low. This leads to increased concentration of bradykinin, which
results in fluid leakage from the blood vessels, followed by swelling.
 Purified concentrate of C1 esterase inhibitors are administered to HAE affected patients
for the prophylactic and acute attack treatment of HAE. Several drugs have been approved
for the prophylactic and acute attack treatment of hereditary angioedema.
 Growth of the global hereditary angioedema treatment market can be attributed to rise
in the prevalence of hereditary angioedema and increase in awareness about HAE across
the globe.
 North America dominated the global market during the forecast period, due to a
comparatively better reported ratio for hereditary angioedema cases.

Request a PDF Brochure - https://www.transparencymarketresearch.com/sample/sample.php?

flag=B&rep_id=74333

Increase in Awareness about Hereditary Angioedema and Novel Pipeline Drugs to Drive
Market

 Government organizations and other agencies are creating public awareness through
various campaigns regarding the diagnosis, treatment, and care of hereditary angioedema.
Moreover, the prevalence of rare diseases across the world is increasing, and most of these
are genetic disorders.
 The U.S. Hereditary Angioedema Association (U.S. HAEA) organized a fundraising event
and other campaigns in September 2017 to create awareness about the disorder within the
community. Such campaigns boost the growth of the global hereditary angioedema
treatment market.
 Promising pipeline drugs and novel therapies by major companies are also fueling the
growth of the global hereditary angioedema treatment market.
 For instance, BioCryst Pharmaceuticals has developed an oral drug - BCX7353 - for the
prophylactic treatment of HAE, which has completed the phase II clinical trial.
 Moreover, increase in the intensity of attacks of severe edema due to high estrogen
levels and rise in the usage of ACE inhibitors that trigger an attack of HAE are the major
factors driving the global hereditary angioedema treatment market.

Kallikrein Inhibitors to be Promising Drug Class

 In terms of drug class, the global hereditary angioedema treatment market has been
classified into C1 esterase inhibitors, selective bradykinin B2 receptor antagonists, kallikrein
inhibitors, and others.
 The C1 esterase inhibitors segment dominated the global market in 2018. However, the
segment is anticipated to lose market share by the end of 2027, due to expiration of the
market exclusivity of certain drugs in major markets, and expected launch of other class of
drugs during the forecast period.
 The C1 esterase inhibitors segment has been bifurcated into plasma products and
recombinant products. The plasma products sub-segment comprises approved drugs such
as Berinert, Cinryze, and Haegarda. The recombinant products sub-segment consists of only
one approved product - Ruconest.
 The kallikrein inhibitor segment has been split into Kalbitor and Takhzyro. The segment
is expected to grow at a higher CAGR during the forecast period, owing to the launch of
Takhzyro, a blockbuster drug in the U.S., and expected approval in other markets in the new
few years.
 The selective bradykinin B2 receptor antagonists segment consists of only one approved
product - Firazyr. The others segment has been bifurcated into conventional drugs and
pipeline drugs.

Request for Analysis of COVID19 Impact on Hereditary angioedema market -

https://www.transparencymarketresearch.com/sample/sample.php?
flag=covid19&rep_id=74333

Subcutaneous Injection Route of Administration Dominates Global Market

 Based on route of administration, the global hereditary angioedema treatment market

has been divided into intravenous, subcutaneous injection, and oral.
 The subcutaneous injection segment dominated the global market in 2018, and the
trend is likely to continue during the forecast period. Patient convenience and new product
launches such as Haegarda and Takhzyro in 2017 and 2018, respectively, are the major
factors driving the segment in the global hereditary angioedema treatment market.

Retail Pharmacies Prominent Distribution Channel

 In terms of distribution channel, the global hereditary angioedema treatment market

has been categorized into hospital pharmacies, retail pharmacies, and others.
 The retail pharmacies segment is projected to dominate the global hereditary
angioedema treatment market during the forecast period, owing to increase in the number
of retail pharmacies, easy accessibility, and additional services provided by specialty
pharmacies.
 The others segment, comprising online pharmacies and mail pharmacies, is anticipated
to be more lucrative during the forecast period. The segment is expected to expand at a
 higher CAGR during the forecast period, due to increase in the preference for online
pharmacies and discounted rates at these pharmacies.

Buy now Hereditary angioedema market Report -

https://www.transparencymarketresearch.com/checkout.php?rep_id=74333&ltype=S

North America to Dominate Global Hereditary Angioedema Treatment Market

 The global hereditary angioedema treatment market has been segmented into three
major regions: North America, Europe, and Rest of the World.
 North America accounted for a major share of the global hereditary angioedema
treatment market in 2018, and is projected to dominate the market during the forecast
period.
 High prevalence of hereditary angioedema, comparatively better reported ratio for
diseases, high healthcare expenditure, and availability of specialty HAE products are the
major factors boosting the growth of the hereditary angioedema treatment market North
America.
 Rest of the World is anticipated to be a highly lucrative hereditary angioedema
treatment market during the forecast period, due to factors such as rise in the number of
reported cases of hereditary angioedema in recent times, increase in awareness in
developing countries about rare diseases, and introduction of novel therapies.

Global Hereditary Angioedema Treatment Market: Competitive Landscape

 Shire plc (Takeda Pharmaceutical Company Limited), CSL Limited, and Pharming Group
NV are leading players in the global hereditary angioedema treatment market.
 The global hereditary angioedema treatment market is projected to be driven by novel
therapies and pipeline products during the forecast period. These pipeline products are in
various clinical trial phases, and are expected to be launched in the next few years.  
 New product approvals for specific indications, robust R&D expenditure & pipeline
products, and mergers & acquisitions are the key strategies adopted by major players in the
global hereditary angioedema treatment market
 Ionis Pharmaceuticals, Inc., BioCryst Pharmaceuticals, Inc., KalVista Pharmaceuticals
Ltd., and Attune Pharmaceuticals have several different products in the pipeline for the
treatment of HAE.

More Trending Reports by Transparency Market Research:

https://www.prnewswire.com/news-releases/rising-number-of-sports-injuries-and-
consequent-surgeries-to-help-medical-dynamometer-market-to-reach-us984-6-mn-valuation-
by-2026--finds-tmr-301187230.html
https://www.prnewswire.com/news-releases/care-delivery-models-in-telemedicine-market-
aim-at-reducing-patient-burden-market-to-clock-robust-cagr-of-14-0-from-2019-to-2027-tmr-
301190294.html

https://www.prnewswire.co.uk/news-releases/closed-system-transfer-devices-market-to-
observe-notable-growth-due-to-increase-in-use-of-oncology-drugs-and-emergence-of-novel-
protocols-in-pharmaceutical-industry-says-tmr-825812545.html

About Us

Transparency Market Research (TMR) is a global market intelligence company providing

business information reports and services. The company’s exclusive blend of quantitative
forecasting and trend analysis provides forward-looking insights to thousands of decision
makers. TMR’s experienced team of analysts, researchers, and consultants use proprietary data
sources and various tools and techniques to gather and analyse information.

TMR’s data repository is continuously updated and revised by a team of research experts so
that it always reflects the latest trends and information. With extensive research and analysis
capabilities, Transparency Market Research employs rigorous primary and secondary research
techniques to develop distinctive data sets and research material for business reports.

Contact

Transparency Market Research

90 State Street, Suite 700
Albany, NY 12207
Tel: +1-518-618-1030
USA - Canada Toll Free: 866-552-3453
Website: https://www.transparencymarketresearch.com/