LEARNING OBJECTIVES:

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Review : Describe the embryology, anatomy, and physiology of Adrenal Gland.

Explain steroidogenesis: biosynthesis of cortisol and adrenal androgens, effect of

ACTH on
adrenal cortex & steroidogenesis.

Explain the HPA Axis

Describe transport of cortex adrenal hormone.

Explain the steroid signal transduction.

Explain the biologic effect of glucocorticoid, mineralocorticoid and adrenal

androgen

Explain the general concept of endocrine system/hormone disorder & disorders of

adrenocortical insufficiency (primary & secondary)

Describe the Evaluation and basic principle of adrenocortical insufficiency

Describe the pathogenesis and pathophysiology of Cushing's Syndrome.

Explain clinical characteristic (including psychiatric sign and symptoms) of

Cushing's Syndrome.
Explain diagnostic tools to diagnose Cushing's Syndrome.

Give treatment of Cushing's Syndrome.

Explain the pharmacological properties of corticosteroid

Select the appropriate drug in Cushing's disease and adrenal crisis

Explain the importance of tapering off corticosteroid.

Evaluate doctor's duty to be able to communicate properly with patients from

various social and
educational background.