PATHOPHYSIOLOGY OF ISCHEMIC STROKE (PATIENT BASED)

Modifiable Factor: Non-modifiable factor

 Sedentary lifestyle  Gender (Male)
- 30 years smoker (1-2 pack/day)  Age (62 years old)
- Alcohol drinker (3-4 times/ week)  Family history of stroke
- High fat diet
 Hypertensive (15 years)
 Overweight (BMI= 28.7)
 Diabetes II (10 years)

Occurrence of fatty plaques lining the blood vessel

(Cholesterol level of 274 mg/dl)

Blood vessel become narrowed (arteries leading to or within

the brain) blood flow reduced in some parts of the body Results in numbing sensation
(<2ml/100mg per minute) and paralysis

Livers produces protein called Lack of oxygen results in anaerobic Glycolysis that Change in ph Less efficient
prothrombin to helps blood for clothing produces lactic acid anaerobic respiration
– RR: 23

Acidic blood slows time to clot – Blood rushes to compensate oxygen insufficiency
Prothrombin time test is 20 seconds resulting in high blood pressure – 200/100 mmHg
PR- 112 bpm
 Low production of ATP (energy) Cell injury and death

Manifestation of
- Numbness of the face
- Right sided body weakness
- Facial asymmetry
- Slurring of speech
- Severe headache
- Dizziness and loss of balance

ISCHEMIC STROKE