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INTRODUCTION OF

PHYTOCHEMISTRY
apt. Rani Rubiyanti, M.Farm
2021
Phytochemical
Definition
What is Phytochemistry?
Phytochemistry Phyto = Plant
Secondary
Metabolites
Chemistry = Natural Material
Chemistry

Extract

Extraction

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Metabolit sekunder

Farmakognosi VS Fitokomia Biosintesis

Cara deteksi
Bagian atau segi mempelajari zat
kimia dari berkhasiat dalam
farmakognosi tumbuhan
Isolasi

Identifikasi

Penetapan kadarnya

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History of
Phytochemistry
A brief History

At the beginning of the development of medical


and pharmaceutical science in the western world,
everything related to medicine and its use was
called "Materia Medica" or medicinal ingredients.

In the early 19th century the medica


material was divided into pharmacology
and phytochemical pharmacognosy

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Pharmacology • drug action mechanism
• all aspects of medicine with a slight emphasis on
Pharmacognosy the mechanism of action of the drug (all
Phytochemistry information relating to drugs of natural origin:
plants, animals, minerals, microorganisms)
Medical
• The science of drug synthesis
chemistry

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Utilization of whole plant parts
(herbs) for medicine by ordinary Most of the pharmaceutical
people → dissatisfaction with industry → search for herbs with
the effectiveness and price of a folklore reputation
modern medicine, appreciation (ethnomedicine for use as a
of everything that smells new drug / prototype drug)
"natural or organic"

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Maintain health

Cure disease
Pharmacognosy began
when humans first
managed disease
Overcoming symptoms
of illness and pain

Health food and drinks


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Guarantee for Consumers
✢ Plant authenticity (genus, species)
✢ Contamination (insects, pesticides, heavy
metals, radiation)
✢ Counterfeiting (addition of medicinal chemical
compounds)
✢ Standardization (biology and chemistry)
✢ Stability Storage
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Scope of
Phytochemistry
In the scientific field of
PHYTOCHEMISTRY

Phytochemical research is closely


related to and supports each other,
a.l. pharmacognosy, pharmacology,
galenic pharmacy, pharmaceutical
chemistry, plant physiology and
biochemistry, chemotaxonomy, /
even formulation of natural
ingredients
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The Role of
Phytochemicals in the
Development of
Pharmaceutical
Sciences
In the field of Plant Physiology
• determining the structure, the origin of biosynthesis,
the work of plant hormones

In the field of Plant Pathology


• determine the chemical properties of phytotoxins
(the result of microbial synthesis that is formed in
high growth) and phytoalexin (high-yield metabolic
products in response to microbial attack)

In the field of Plant Systematics is a hybrid


discipline between chemistry & taxonomy
• Chemotaxonomy
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Thanks!
Any questions?

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