Questionnaire

Principles of inheritance

Question, 1 Select the correct match

(a) Sickle cell Anaemia—Autosomal recessive trait
(b) Thalassemia –X linked
(c) Haemophilia ---Y linked
(d) Phenylketonuria---Autosomal dominant trait

Question 2. Chromosomal theory of inheritance was proposed by

(a) Sutton and Boveri
(b) Bateson and Punnet
(c) T.H. Morgan
(d) Watson and Crick

Question 3. The number of contrasting characters studied by Mendel for his

experiment was

(a) 14
(b) 4
(c) 2
(d) 7

Question 4. What is the genetic disorder in which individual had masculine

development gynaecomastia and sterile
(a) Edward syndrome
(b) Downn syndrome
(c) Turner syndrome
(d) Klinifelter s syndrome
Question 5. A gene locus has two alleles A and a if the frequency of dominant
allele is 0.4 then what will be the frequency of homozygous dominant,
heterozygous and homozygous recessive individual s in the population
(a) 0.16 (AA) 0.48 (Aa) and 0.36 (aa)

(b) 0.16 (AA) 0.36 (Aa) and 0.48 (aa)

(c) 0.36 (AA) 0.48 (Aa) and 0.16 (aa)
(d) 0.16(AA) 0.24 (Aa) 0.36 (aa)

Question 6. In which genetic condition each cell in the affected person, has three
sex chromosomes xxy
(a) Thalassemia
(b) Klinefelter’s syndrome
(c) Phenylketonuria
(d) Turners syndrome

Question 7.Select the correct match

(a) T.H. Morgan ----Transduction
(b) F2 recessive parents—Dihybrid cross
(c) Ribozyme –Nucleic Acid
(d) Gregor Mendel –Transformation

Question 8. A woman has an X linked condition on one of her X chromosomes.

This chromosome can be inherited by
(a) Only grandchildren
(b) Only son
(c) Only daughters
(d) Both (B) and (C)

Question 9 which characteristic represent s inheritance of blood groups in

humans
1. Dominance 2. Codominance 3. Multiple allelism 4. In complete
dominance
(a) 2, 4, 5
(b) 1, 2 ,3
(c) 2,3, 5
(d) 1, 3, 5

Question 10. Which of the following is wrongly matched?

(a)XO type sex determination—Grasshopper
(b) ABO blood grouping - Codominance
© Starch synthesis in pea—Multiple alleles
(e) T. H Morgan---Linkage

Question 11. The genotype of husband and a wife are as IaIB and I ai . Among the
blood types of their children, how many genotypes and phenotypes are
possible?
(a) 3 genotype : 3 Phenotypes
(b) 3 genotypes :4 Phenotypes

(c) 4 genotypes :3 Phenotypes

(d) 4 genotypes :4 Phenotypes

Question 12. Thalassaemia and sickle cell anaemia are caused due to a problem in
(a) Both are due to qualitative defect in globin molecule synthesis
(b) Both are due to quantitative defect in globin molecule synthesis
(c) Thalassaemia is due to less synthesis of globin molecule
(d) Sickle cell anaemia is due to a quantitative problem of globin molecule

Question 13. In a rest cross, involving dihybrid flies, more parental type offsprings
were produced than the recombinant type offspring . this indicates
(a) Chromosomes failed to separate during meiosis
(b) The two genes are linked and present on the same chromosome
(c) Both the characters are controlled by more than one gene
(d) The two genes are located on two different chromosomes.
Question 14Match the terms in column 1and column II

Column1 Column II
Dominance Many genes goveren in a single
character
Codominance In a heterozygous organism only
one allele expresses itself
Pleiotropy In a heterozygous organism both
the allele expresses themselves
fully
Polygenic inheritance Asingle gene influences many
characters

A B C D
A Ii iii iv i
B Iv i ii iii
C Iv iii i ii
D Ii i iv iii

Question 14. If a colourblind man marries a normal woman who is heterozygous

for the normal colour vision , the probability of their son being colour blind
is
(a) Zero
(b) 0.5
(c) 0.75
(d) 1.0
Question 15.which of the following is more appropriately describes haemophilia .
(a) X linked recessive gene disorder
(b) Chromosomal disorder
(c) Dominant gene disorder
(d) Recessive gene disorder
Question 16. A tall true breeding garden pea plant is crossed with a dwarf true
breeding garden pea plant. When the F1 plants were selfed, the resulting
genotypes were in the ratio of
(a)1:2:1 , Tall heterozygous :tall homozygous :Dwarf
(b)3:1Tall and Dwarf
(C) 3:1 dwarf and tall
(d) 1:2:1 , Tall homozygous :tall heterozygous: Dwarf
Question 17. A true breeding plant is
(a) One that is able to breed on its own.
(b) Produced due to cross pollination among unrelated plants
(c) Near homozygous and produces offspring of its own kind
(d) Always homozygous recessive in its genetic constitution.
Question 18. Pick the correct option
1. Haemophilia is a sex linked recessive trait
2. Down syndrome is due to aneuploidy
3. Phenylketonuria is an autosomal recessive gene disorder
4. Sickle cell anaemia is an x linked recessive gene disorder
(a) 2 and 4 are correct
(b) 1 , 3 and 4 are correct
(c) 1 , 2 and 3are correct
(d) 1 and 3 are correct

Question 19. Alleles are

(a) Different phenotypes
(b) True breeding homozygotes
(c) Different molecular forms of a gene
(d) Heterozygotes
Question 20. A man with blood group A marries a woman with blood group B
what are the possible blood groups of their offsprings.
(a) A and B
(b) A , B and AB
(c) A, B, AB and o
(d) Only o

Question21. Multiple alleles are present

(a) On different chromosomes
(b) At different loci on the same chromosomes
(c) At the same locus of the chromosome
(d) On non sister chromatids.

Question22. The term linkage was coined by

(a) W.Sutton
(b) T.H. Morgan
(c) T.Boveri
(d) G. Mendel

Question23. A Pleotropic gene

(a) Controls multiple traits in an individual
(b) Is expressed only in primitive plants
(c) Is a gene evolved during Pliocene
(d) Controls a trait only in combination with another gene
Question25. A gene showing codominance has
(a)Both alleles independently expressed in the heterozygotes
(b) one alleles dominant on the another
© alleles tightly linked on the same chromosome
(e) Alleles that are recessive to each other
Question26. A colourblind man marries with the daughter of a colourblind father,
the generation will be
(a) There will be no daughter colourblind
(b) All sons will be colourblind
(c) All daughters will be colourblind
(d) Half sons will be colourblind

Question27. In a plant , red fruit (R) is dominant over yellow fruit ( r) and tallness
(T) is dominant over shortness (t). If a plant with RRTT genotype is crossed
with a plant that is rrtt , then
(a) 25% will be tall with red fruit
(b) 50% will be tall with red fruit
(c) 75% will be tall with red fruit
(d) All will be tall with red fruit

Question28. A colourblind man marries a woman with normal sight who has no
history of colourblindness in her family. What is the probability of their
grandson being colourblind
(a) 0.5
(b) 1.0
(c) Nil
(d) 0.25
Question29.A human female with Turner’s syndrome has
(a) 45 chromosomes with XO
(b) One additional X chromosomes
(c) Exhibits male character
(d) Is able to produce children with normal husband

Question 30. If both parents are carrier for Thalassemia, which is an

autosomal recessive disorder, what are the chances of pregnancy resulting
in affected child
(a) 50%
 (b) 25%
(c) 100%
(d) No chances
Q. 31. When Aa is crossed with aa (A is dominant over a
(a) All the offspring will have dominant phenotypes.
(b) ) All the offspring will have recessive phenotypes
©) 50% offspring will have dominant phenotypes and 50% offsprings will have
recessive phenotypes.
( d ) 75% offspring will have dominant phenotypes and 50% offsprings will have
recessive phenotypes.
Q. 32. A heterozygous violet flowered pea plant is crossed with another
homozygous violet flowered pea plant. What percent of the progeny plant will
have recessive trait, white flowers.
(a) 0%
(b) 25%
(c ) 50%
(d )75%
Q. 33. From a cross AABbX aaBb, the genotypes AaBB:AaBb: Aabb will be obtained
in the ratio
(a ) 1:1:2
(b) 1:2:1
(c )2:1:!
(d ) 2:1:2
Q.34. The possibility of all genotypes of offspring in a genetic cross is calculated by
a graphical representation which was developed by
(a) Korenberg
(b) T.H. Morgan
(c ) Gregor Mendel
(d )Reginald Punnet
Q.35. A woman with normal vision has a colourblind father. She marries a
colourblind man. What proportion of children will be colourblind?
(a ) 0%
(b ) 25%
(c ) 50%
(d ) 100%
Q. 36. Occasionally a single gene may express more than one effect. The
phenomena is called
(a) multiple allelism
(b ) Mosaicism
( C) Pleiotropy
(D ) polygene
Q.37. Which of the following are the correct for the inheritance of genes involved
in ABO blood grouping.
(a) It is inherited by complete dominance
(b) ) It is inherited by complete recessive allele
(c) ) It is inherited by codominant allele
(d) ) It is inherited by incomplete dominant allele
Q.38Mendelian principles are not applicable in case of
(a) Sex linked allele
(b) Asexually reproducing forms
© Sexually interbreeding forms
(d ) Diploid homozygous forms
Q.39. Which is gynandromorphs
(a) Drosophila
(b) Beetles
(C ) silkworms
(D) all of these
Q.40. Select the correct statements from the following.
( a) Linkage is an exception to the principle of independent assortment in heredity
(b) Galactosemia is an inborn error of metabolism
(c ) small population size results in random genetic drift in a population
(d ) Baldness is a sex limited trait
Assertion / Reason
Q. 41. Assertion: Genes are not passed on from one generation to the next.
Reason: Genes serves as the units of inheritance.
Q.42 Assertion :In codominance, the F1 generation resembles both the parents.
Reason : An example is different type of red blood cells that determine ABO blood
grouping in humans.
Q.43. An insect show female heterogamety.
Reason In insect males have XO sex chromosome and females have xx sex
chromosomes.
Q.44. Down syndrome, Klinefelter’s syndrome and Turners syndrome are
chromosomal disorders.
Reason: In klinefelters syndrome females are sterile.
Q. 45. Assertion: Down syndrome is a mendelian disorder.
Reason: It is caused due to the presence of an additional copy of chromosome 21.
Fill in the blanks
Q.47. The two chromatids of a chromosome are held together at the -------------
Q. 48. Chromosome theory of inheritance was proposed by ------------ and ----------
Q. 49. In humans males are heterogametic whereas females are -----------------
Q.50. Non separation of homologous chromosomes during meiosis is termed
as-------------
Q. 51 The point at which crossing over takes place are known as --------
Q.52. The chromatids affected by the crossing over are termed as --------
Q. 53.The hereditary units present in the cytoplasm are called------.