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Adult Patients ≥ 40 kg. Notify MD immediately as patient may need intubation.

Assessment at Triage: Initiate HFNC at 100% or


• Respiratory Rate YES Initiate GO2VENT at:
ROX score at triage
• SpO2 • Adjust pressure knob to 25-30 cm-H2O.
≤4
• FiO2 (nasal cannula 0.04/liter • 40 LPM at 100% FiO2 in assist setting.
added to 0.20) • Maintain RASS between 0 and 1.
• Check vitals (BP, temperature)

NO Perform ABG.
Titrate oxygen for SpO2 > 88%.
Ensure patient has patent IV access. Maintain RASS between 0 and 1.
Prepare for intubation using sedation. Verify ROX score 4-6: Initiate GO2VENT.
patient wishes and code status. • 15 LPM at 50% FiO2
Make decision to intubate or palliate. At 1-hour mark: • Adjust pressure knob to 20-25 cm-H2O.
• Titrate oxygen for SpO2 ≥ 90%. YES ROX < 4 • Place PEEP valve in line. Continue only as tolerated.
• Initiate sedation for score of -1 to -2. and/or pH ≤ 7.45 ROX score > 6: Initiate high flow nasal cannula.
and/or HACOR > 5 • Maintain SpO2 ≥ 88%.

ROX score 4-6: Continue therapy. NO


ROX score > 6: Consider weaning PIP
gradually.
•If ROX score improves, maintain current therapy.
Continue proning as tolerated.
•If ROX score and HACOR score are unchanged,
increase PIP to 30 cm-H2O and increase PEEP.
•If HACOR score improves, maintain current therapy.
•If pH is 7.40-7.45, maintain current therapy.
ROX < 4
and/or NO •If pH is > 7.45, increase PIP to 30 cm-H2O and
increase PEEP.
At 2-hour mark: pH ≤ 7.40
Maintain RASS between 0 and 1.
Repeat ABG, ROX score, and/or After each hour, repeat Step 8.
HACOR score, and RASS score. HACOR > 5

YES Notify physician.


Prepare for chemically assisted intubation.
Optimize oxygen delivery to keep SpO2 > 90%.
Verify patient wishes: Intubation vs. palliate.

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