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COVID-19 PREPAREDNESS AND RESPONSE: IMPLICATIONS FOR FUTURE PANDEMICS

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From response to transformation: how countries
can strengthen national pandemic preparedness
and response systems
Victoria Haldane and colleagues delve into the characteristics of national responses to covid-19.
They suggest actionable steps at a national level that can guide states to achieve the independent
panel’s recommendations for making this the last pandemic

A
s the second year of the covid- mitigate the spread and impact of covid-19 Based on an analysis of 28 national
19 pandemic ends, we are can shed light on strengths and weaknesses responses to covid-19 in the first year
confronted with the reality in national pandemic responses. These of the pandemic (box 1), we discuss
that national responses thus responses not only shaped the course of the the characteristics of high performing
far have resulted in more than pandemic in 2020, but also laid a founda- responses and low performing
259 million cases and 5.17 million deaths tion for enduring impacts on health, soci- responses, and offer a way forward to
globally as of 23 November 2021. Thus, we eties, and the economy. They influenced sustain momentum and move towards
reflect on the path that led us here and les- decisions about vaccine prioritisation and implementing the recommendations of
sons to prevent further health, social, and delivery programmes, and gave evidence the Independent Panel for Pandemic
economic losses related to the pandemic.1 to support the view that covid-19 is an Preparedness and Response. 1 High
2
Examining the quality of early efforts to endemic disease.3-6 Thus, we are now at a performing responses are defined as
pivotal moment to consider the character- those countries that had the least number
istics of national responses to covid-19 and of deaths directly related to covid-19
KEY MESSAGES take stock of the qualities that differentiate per capita in November 2020, and low
a high performing from a low performing performing those with the highest fatality
•   A s we enter the third year of the approach. numbers (box 1).
covid-19 pandemic, we are at a piv-
otal moment to consider the char-
acteristics of national responses, to Box 1: Methods
understand our next steps and to
We selected 28 countries on 6 November 2020, reflecting the reported death toll at the time
prepare for future infectious hazards
(box 2). Countries selected include positive and negative outliers in relation to reported covid-
•   High performing national responses 19 deaths per capita among highly populous countries, as well as countries in the middle
to covid-19 are characterised by co- ground from different regions and with widely varying health systems and economic statuses.
ordinating, developing, and strength- Given the evolving nature of the pandemic, we acknowledge that performance measured
ening a suite of public health, health in reported deaths per capita has since changed. Ethical approval was obtained from the
system, and socioeconomic measures National University of Singapore.
to prevent or break chains of trans- Three complementary methods were adopted and triangulated to analyse national
mission in communities responses to covid-19:
•   Low performing countries’ national • Literature review—Using standardised methods, we identified peer reviewed papers and
approaches were hindered by deval- public reports that examined national and subnational policy responses and extracted data
uing, denial, delays, and distrust. for each country on five dimensions comprising 62 items. The dimensions and items were
Interventions ultimately prevented identified through a review of 14 existing frameworks.
co-ordinated national efforts or ren- • Semi-structured interviews and national government submissions—A total of 43 interviews
dered them ineffective in breaking and written submissions were provided between November 2020 and April 2021. Semi-
chains of transmission in communi- structured interviews with covid-19 national experts in policy, operations, and academia
ties were recorded and transcribed in full. Interviewees were based across Europe, North
•   To implement recommendations of America, South America, Africa, and Asia, with representatives spanning the four sectors.
the Independent Panel for Pandemic All interviews were coded through an inductive approach and thematic analysis, using QSR
Preparedness and Response, we pro- NVivo 12 Software, drawing on techniques of the constant comparison method.
pose 15 actionable next steps for • Validation of country specific data—Semi-structured interviews, written consultations,
responding to emergent pandemic and round table discussions were conducted with 45 country experts. When we identified
threats, preparing and maintaining conflicting information from different sources, we validated our data by contacting experts
resilient health systems for pandemic to help address and resolve inconsistencies. In March 2021, national and international
response, and transforming to build experts in covid-19 policies participated in two round table discussions. Experts reflected
intersectional approaches centred on the findings and provided written or verbal feedback. Experts also provided short
on community trust and enabled by presentations of their own countries, which were then used by the research team to validate
equitable societies the data in the report.

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COVID-19 PREPAREDNESS AND RESPONSE: IMPLICATIONS FOR FUTURE PANDEMICS

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Public Health Preparedness Clinics scheme hindering governments, government
Box 2: Selected countries
to provide triage support and government institutions, and the bureaucratic
• Africa—Liberia, Mozambique, Niger, subsidised treatment (based on haze apparatus from enacting or developing
Nigeria, Uganda events and H1N1), and the National Centre plans.19 The denial of scientific evidence
• Asia Pacific—China, Fiji, India, Japan, for Infectious Diseases, a 330 bed facility, was compounded by a failure of leadership
New Zealand, Pakistan, Singapore, South provided specialised infectious disease to take responsibility or make cohesive
Korea, Sri Lanka, Thailand, Vietnam services (based on experience with severe strategies towards breaking chains of
• Europe—Germany, Russia, Spain, acute respiratory syndrome). 10-12 The transmission in communities.20 21 Similarly,
Sweden, UK Singapore government further prioritised these countries often had historically
• Middle East—Egypt domestic research and development, underfunded public health systems,
• North America—Mexico, US coupled with production, to ensure resource rendering the supporting infrastructure
• South America—Argentina, Brazil, Peru, availability. South Korea strengthened unable to quickly identify outbreaks and
Uruguay relationships with private sector partners take rapid and comprehensive action to
and biotechnology companies in the break chains of transmission. 22 Denial
High performing responses: partner, years between the outbreak of Middle of social and economic supports in low
coordinate, develop, and strengthen East respiratory syndrome and covid- performing countries largely affected those
High performing responses during the first 19, resulting in timely public-private working in the informal labour market,
year of the pandemic were characterised by partnerships that delivered early diagnostic particularly in countries with lengthy
approaches and actions to partner, coordi- reagents for covid-19. In communities, high lockdown measures.23 24
nate, develop, and strengthen a suite of performing countries developed people Delays featured in all low performing
public health, health system, and socioeco- centred communication strategies. 13 responses to varying degrees. Many
nomic measures to prevent or break chains Liberia even trained its community leaders countries took a “wait-and-see” approach
of transmission in communities. National on the epidemiology of the disease to a n d d e l aye d l au n c h i ng re s p o n s e
approaches were of course informed by support containment efforts, and the Thai mechanisms, making decisions, and
broader contextual factors, such as his- government deployed its extensive network changing course based on evolving
tory, geography, politics, economics, trust, of one million village health workers to scientific evidence. The British government
recent history responding to outbreaks, disseminate and amplify messages in the has oscillated between holding off public
and other antecedents shaping decisions, community. 14 New Zealand is another health measures to spare the economy
including at the highest level of govern- example of robust and people centred and strict lockdowns when the public
ment. Yet, when high performing country communication by design, with intention health system was already stretched to its
responses during 2020 are drawn together, to reach all communities.15 16 Indeed, the limits with covid-19 patients.25 26 However,
these four common themes persist. government’s emergency plan explicitly these delays in changing approaches,
High performing countries’ responses considered Indigenous groups and their especially in the beginning, have had
were informed by partnership on multiple access to healthcare and welfare services, detrimental effects on rates of covid-19
levels, through a whole-of-government although some inequalities persist.17 infection and deaths as hospitals and the
approach, engaging with communities, health workforce were already at capacity
and participating in purchasing Low performing responses: devalue, denial, limits. Crucially, the government created
partnerships to secure resources (table delay, and distrust blanket regulations without further
1). High performing countries also showed Many low performing responses appeared consideration of how lockdowns affect
coordination at all levels of the response. to have comprehensive approaches on specific populations.27
Uruguay is a case in point. Covid-19 paper. However, caveats and gaps exist, Distrust was a powerful undercurrent
coordination bodies were established which, when taken together, failed to pro- throughout low performing national
at the national and subnational levels, tect communities from covid-19. Overall, responses. Concerningly, in many low
with the president providing overall these national approaches were hindered performing countries, leadership was
leadership.7 The Ministry of Public Health in various ways and to varying degrees by sceptical or dismissive of emerging
led the national response, with reports of devaluing, denial, delays, and distrust that scientific evidence, which contributed to
strong coordination between the national ultimately either prevented coordinated undermining public trust in the response.
ministries and departmental health national efforts, or rendered them ineffec- This was exacerbated in many low
directorates, which efficiently implemented tive in breaking chains of transmission. performing countries by political leadership
protocols and contingency plans.8 High While low performing countries had politicising the pandemic. In the lead
performing countries also coordinated to pandemic preparedness plans, these were up to Uganda’s presidential election in
ensure adequate translation of evidence devalued and rendered ineffective by a January 2021, the UN High Commissioner
into policy and practice. In Mozambique, lack of adequate infrastructure to rapidly for Human Rights accused authorities
for example, the Technical-Scientific mobilise and sustain outbreak response of enforcing covid-19 restrictions “more
Commission was convened to include those measures (table 2). This was exacerbated strictly to curtail opposition electoral
with expertise in public health, media, by most low performing countries denying campaign activities in a discriminatory
social science, and other sectors to inform the threat of covid-19 either through word fashion.”28
the national response.9 or action.18 In countries where heads of state
High performing countries focused on openly denied the risk and severity of covid- The middle ground: an ongoing and inequitable
development, including increasing health 19 (eg, Brazil, Mexico, UK, US), pandemic global pandemic
system capacity. Singapore activated its response plans were simultaneously These broad characterisations, while use-
private primary care clinics under the devalued at the highest end of politics, ful to conceptualise the relative strengths

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Table 1 | Four pillars of high performing responses
Partner Coordinate Develop Strengthen
Prior experiences and Previous partnerships with Experience coordinating across Previous investment in public Ongoing strengthening of
preparedness communities leveraged for sectors to mobilise a response health and outbreak response outbreak surveillance networks
outbreak response and risk infrastructure
communications
Scientific advice Worked with experts to form Efforts to translate evidence into Efforts to create new Trust in scientific advice
multidisciplinary committees action by working across sectors technologies (eg, test kits)
to advise leadership on the and with communities and contribute to covid-19
response knowledge generation
Governance and leadership Whole-of-government Multi-ministry task forces or Financing mechanisms to Policies to reduce financial
approaches across sectors. committees provide relief for businesses, barriers to covid-19 testing and
Public-private approaches that individuals, and families treatment
are cost effective, accountable,
and transparent
Health systems and services Engage the community in the Triage and referral processes Capacity in medical facilities Primary and community care.
planning of services with primary and community through temporary facilities and Access to and use of digital
care postponing elective procedures. technologies
Networks of laboratories
Public health Community health workers or Proactive testing and contact Quarantine and isolation Active surveillance mechanisms
other community leaders in high tracing strategies facilities
risk areas or settings
Social and economic supports Multisectoral action to ensure Involve community groups and Financial mechanisms to ensure Social and financial protections
protection against food, housing, local organisations to deliver free covid-19 testing and for communities and small
and income insecurity social supports treatment businesses

and weaknesses of national pandemic surge, others were more conservative. This middle ground approach, and
responses, are by no means mutually Their strategies aimed for containment the absence of meaningful global
exclusive. Examples of devaluing, denial, to the greatest extent possible, but were collaboration, has failed to lead us to
delays, and distrust are seen in aspects of often inconsistent over time. The need to a better and fairer “post-covid world.”
high performing responses, just as low per- maintain public support, and changes Instead, we see a doubling down of the
forming countries made attempts on vary- in public health policies, allowed cases status quo, where those most marginalised
ing scales and to varying degrees to partner, to surge in waves. These policies were are disproportionately affected by an
coordinate, develop, and strengthen their backed by social and economic supports ongoing pandemic. Since its emergence in
responses. Indeed, pandemic responses are that were temporary or did not reach the late 2019, covid-19 has led to a dramatic
complex systems, comprised of feedback whole population. Some countries only loss of human life, left health systems and
loops and characterised by path dependen- took robust efforts to protect their most health workers in shock and stress, and
cies and non-linear interactions that chal- vulnerable after significant outbreaks in triggered economic and social disruption
lenge evaluative efforts. crowded settings or in specific populations, on a global scale, with the most devastating
As a result, many countries’ responses such as migrant workers. The whole of effects on already vulnerable populations.
to covid-19 fell in the middle ground a national response to covid-19 is more After two years of pandemic response,
during 2020, exhibiting both high and than the sum of its parts. If what countries countries continue to oscillate between
low performing characteristics. While did was often similar, how and when they learning to partner, coordinate, develop,
some countries took aggressive action to implemented measures, and when they and strengthen, and continuing to
strengthen their response after an initial took action differed. devalue, deny, delay, and distrust. Against

Table 2 | Four pillars of low performing response


Devalue Denial Delays Distrust
Prior experiences and Pandemic preparedness Not taking seriously threats of Wait-and-see approach in Failure to acknowledge
preparedness plans did not have adequate emerging infectious disease launching response mechanism prior warnings of impacts of
infrastructure to rapidly mobilise pandemics
Scientific advice Influence of scientific Scientific evidence was not Lack of coordination between Leadership appeared sceptical or
committees waned over time translated into actionable scientific committees and dismissive of emerging scientific
policies by leadership leadership to quickly inform evidence, eroding public trust
policy change
Governance and leadership Lack of coordination between Refusal to take action or Wait-and-see approach to Politicising the pandemic
national and subnational responsibility for the response decisions or changing course
responses based on evidence
Health systems and services Historically fragmented and/ Covid-19 testing and care not Reactionary measures to Hesitancy to seek care, given
or resource constrained health universally covered increase health system capacity. overcrowding and high case
systems Fewer mechanisms to link numbers/fatalities
patients to primary care for
routine care
Public health Historically underfunded Prioritising single interventions Delays in widespread testing Lack of consistent public support
public health systems and over comprehensive measures and contact tracing before for public health measures
infrastructure community transmission
Social and economic supports Supports were not enough to Supports were not maintained Lack of mechanisms to ensure Unclear eligibility or
make up for lost wages or other over time or excluded groups widespread access misappropriated supports
needs

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a backdrop of pervasive and unchecked The image of the iceberg captures the approaches centred on community trust
vaccine inequity, for many countries and complex interplay of factors, drivers, and enabled by equitable societies.
communities the most devastating surges and contexts that need to be reflected in
have happened despite the availability recommendations (fig 1).31 32 The visible Responding to emerging pandemic threats
of several safe and effective vaccines. part of the iceberg represents things that are Progress can be made if nations are
Currently, the different strategies are seen, like the public health interventions equipped to respond to ongoing and novel
most visibly playing out, as countries and countries enacted. Just below the water are threats by making science based decisions
governments start to recognise the endemic those programmatic and systems elements to protect lives and livelihoods. Early and
nature of covid-19 and decide how to best that need to be prepared or maintained to decisive implementation of public health
move forward.29 As many countries have support the response. The bottom of the measures is dependent on well function-
embarked on roadmaps to start re-opening iceberg contains the structural elements ing public health infrastructure. Yet, pub-
borders and economies, governments that that drive behaviour and the underlying lic health measures alone are insufficient
prematurely dismiss the continuing severity values and beliefs that contribute to as they may not be accessible (vaccines)
of the virus pose risks to their populations such behaviour. Covid-19 has revealed or feasible (lockdowns) at scale. These
and the world, as further mutations of the “underbelly” of the iceberg: the measures must be supported by a social
SARS-CoV-2 hold potential to reignite political tensions, systemic weaknesses, safety net and universal health coverage to
surges in regions that have lower vaccine and vulnerabilities that public health ensure programmatic sustainability, while
coverage. Countries in the global north interventions are built on, and that are built enabling widespread adherence, and pro-
have vaccinated most of their populations into them. It is by reckoning with what has tecting livelihoods.
and are swiftly resuming daily activities, largely remained hidden from view, and 1. Apply public health and social meas-
but it is worth remembering that no one is how these all factor into health outcomes, ures systematically, comprehensively,
safe until everyone is safe. Two immediate that we can learn how to strengthen and with community partnership
issues arise. The first is a responsibility pandemic responses going forward. We in every country at the scale the epi-
to close the vaccine gap between vaccine present the recommendations in three demiological situation requires. All
producing/high income countries and pillars that reflect the iceberg metaphor: countries must have an explicit strat-
low and middle income countries with responding to emergent pandemic threats, egy agreed at the highest level of
low access to vaccines.30 Second, nations preparing and maintaining resilient government to curb transmission of
need to retain flexible public health and health systems for pandemic response, covid-19. Targeted and timely public
social measures based on the changing and transforming to build intersectional health interventions must be centred
epidemiology and hospital capacities, and
be steadfast in implementing these, even
when infections rise following re-opening.

Recommendations: responding, preparedness,


and transformation
React
• Immediate, proactive, and precautionary responses
Given the characteristics of responses to • Public health interventions
covid-19 thus far, we propose 15 recom- • Increase health expenditure for public health
mendations for global, regional, national, infrastructure
and subnational leaders to navigate the
current pandemic as well as future infec-
tious hazards. The role of decision makers,
and the political sphere shaping pandemic
responses, cannot be underestimated,
Prepare and maintain
as covid-19 has laid bare a long known • Resilient health systems
truth—that politics matter in public health. • Socioeconomic support for public health measures
From the local to the global level, pandemic • Invest in multidisciplinary, inclusive, and truly
preparedness and responses can never be independent research
• UHC and people centred approach
apolitical. Thus, recommendations must • Monitoring , evaluation, and cross country learning
be actionable, but also reflective of, and
adaptable to, country or region specifici-
ties. Immediate and medium term actions
are required urgently, but we argue that
national governments must also address
structural challenges in the long term for Transform
health systems to become more equitable • Build equitable societies and shi mindsets
for all. As such, recommendations must • Long term social protection measures and health promotion
• Informed, responsible leaders, and effective co-ordination
capture the requisite complexity necessary • Whole-of-society and whole-of-government approach
to mitigate the health, social, and economic
risks the pandemic poses, to prepare for
future pandemics and to grasp the oppor-
tunities for building more inclusive and
equitable societies. Fig 1 | The covid-19 iceberg model for pandemic preparedness and response

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on human rights and supported by acknowledge that collaboration and any are among the determinants for successes
economic measures. The capacity of form of surveillance, monitoring, and and failures of a response. Thus, achieving
the public health system to perform evaluation are intrinsically political and and sustaining high performing responses
surveillance, testing, contact tracing, must be addressed as such.33 34 requires a shift in mindsets beyond political
and isolation, while upholding human 6. Increase the threshold of national and economic consideration and towards
rights, is critical. health and social investments to build health promotion across sectors and
2. Strengthen the engagement of local resilient health and social protection governance, to create healthy societies.
communities as key actors in pan- systems, grounded in high quality 11. Building resilient and equitable socie-
demic preparedness and response primary and community health ser- ties requires a serious shift in mindsets
and as active promoters of pandemic vices, and a strong and well supported to engage with and create policies that
literacy, through the ability of peo- health workforce, including commu- reflect the broader social, economic,
ple to identify, understand, analyse, nity health workers. environmental, and political factors
interpret, and communicate about 7. Ensure a renewed commitment to in society. Health programmes and
pandemics. universal health coverage (UHC) responses to covid-19 must no longer
3. Build resilient and people centred to ensure high quality care for all. remain gender neutral and community
health systems grounded in high Achieving UHC requires appropriate blind. A change of paradigms must be
quality primary care and integrate financing, not only to prepare for new accomplished through re-politicisa-
the health and public health system pandemics, but to ensure that peo- tion, foregrounding human rights and
together with the long term care sec- ple have access to the health services equality concerns.
tor. This also fosters accountability, they need, when and where they need 12. Targeted and long term social protec-
inclusion, and trust through respon- them, without financial hardship. tion of vulnerable populations should
siveness. 8. Conduct multisectoral active simula- be integral to a whole-of-society
4. Invest in and coordinate risk commu- tion exercises on a yearly basis as a approach, and should offer security
nication policies and strategies that means of ensuring continuous risk in terms of food, housing, and income.
ensure timeliness, transparency, and assessment and follow-up action to 13. Implement a collaborative, gender
accountability. Work with marginal- mitigate risks, improve cross-country responsive, and equitable whole-of-
ised communities, including those learning and accountability, and foster society approach that engages civil
who are digitally excluded, to build a culture of alertness to respond when society, business, and government at
trust and resilience in plans that pro- needed and at the right time. all levels, in acknowledgment of the
mote health and wellbeing at all times. 9. Invest in biomedical, public health, intersectional nature of health and
5. Establish mechanisms for monitor- and social sciences research, build wellbeing, while also dismantling
ing and evaluations at country level. institutional capacities, and establish inherent structural marginalisation
Establish independent and impartial mechanisms and platforms that allow and inequalities.
national mechanisms for monitoring for, and encourage, the exchange of 14. Implement a whole-of-government
the health and social care systems at knowledge, expertise, and innovation. approach that ensures access to health
the country level to prepare for further 10. Ensure that national and subnational services and protection against dis-
waves of covid-19 and for future pan- public health institutions have multi- crimination and vulnerabilities.
demics. disciplinary capacities, multisectoral 15. Heads of state and government should
reach, and engagement with the pri- appoint national pandemic coordina-
Preparing and maintaining systems for vate sector and civil society. Evidence tors accountable to the highest levels of
pandemic preparedness and response based decision making should draw government, with the mandate to drive
Similarly, future pandemic responses on inputs from across society, with the whole-of-government coordination for
must ensure all activities are planned inclusion of diverse social and profes- both preparedness and response.
and implemented with actionable, sional groups (ie, age, ethnicity, race,
independent, and transparent monitoring class, gender, disability). Conclusion
and evaluation mechanisms. The As the covid-19 pandemic evolves, we
architects of pandemic responses, both Transforming and building resilient and must consider how to move from response
decision makers and scientific advisers, equitable societies to transformation. The early response laid
must be accountable to the communities Effort is needed to prepare and a foundation that has led us to far reaching
affected by the pandemic and measures maintain responses grounded in robust health, social, and economic impacts, and
to mitigate its effects. Similarly, while local capacities. Ultimately, the only amplified existing inequities. To navigate
modern surveillance systems generate true preparedness is transformational the coming challenges of the pandemic and
vast amounts of data, these outputs change that prioritises global solidarity, to prepare for future infectious threats will
can be better translated into policy and and protects the health and wellbeing require deep and transformative action.
practice, and international data sharing of people, communities, and the planet. Countries must learn to partner, coordinate,
obligations and mechanisms need to be The pandemic has brought to the fore a develop, and strengthen across a range of
considered. This is but one aspect of wider crisis of governance, highlighting gaps in domains, and we must no longer devalue,
debates on cross-country, regional, and accountability (at all levels), questioning deny, delay, and distrust actions that can
global cooperation to better prepare for practices of representation, power save lives and livelihoods. To sustain
and respond to global health challenges relations, and hierarchies. Indeed, political momentum towards such change requires
through routine data sharing centred in leadership and decision making have been intersectional approaches and a willing-
human rights. To achieve this, we must at the heart of responses to covid-19, and ness to learn our lessons and apply them.

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doi:10.1016/S0140-6736(21)00306-8 25 Scally G, Jacobson B, Abbasi K. The UK’s public
have the following interests to declare: All authors
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