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Causes: Definite cause unknown. Possible causes are as follows:
Alterations in bile composition, such as increased
concentration of cholesterol or decrease in concentration of
phopholipids or bile acids; Failure of gallbladder to empty
adequately; Infection; Hemolytic disorders such as sickle
cell anemia.
Prevention: Avoid risk factors where possible.
Risk Factors
Family history of gallstones.
Genetic factors. Some ethnic groups are more susceptible, such as Native
Americans and Hispanics.
Obesity.
Excess alcohol consumption
Oral contraceptives.
High fat, low fiber diet.
Rapid weight loss.
Women who have had many children.(multiparity)
Hemolytic disorders such as sickle cell anemia, hereditary spherocytosis.
Liver cirrhosis.
Diabetes.
Female gender.
Inflammatory bowel disease such as crohns.
Medications:
For minor discomfort, you may use non-prescription drugs such as
acetaminophen.
Oral medication to try to dissolve stones. This treatment is used for certain
types of stones and can take up to two years.
Activity:
No restriction, except to rest during attacks of gallbladder
colic.
Diet:
During an attack, sip water occasionally, but don't eat.
At other times, eat low-fat diet. Fatty meals may bring on mild attacks.
If you are overweight, begin a weight reduction program.
Possible Complications :
Infection or rupture of the gallbladder.
Common bile duct stone with obstructive jaundice.
Gall bladder cancer.
Small bowel obstruction and paralysis due to gallstone causing
obstruction.
Prognosis
Most people with gallstones have no symptoms. For those who do, the
disorder is curable with surgery.
About 10 to 15% of people with gall bladder stones will have associated
choledocolithiasis (stones in the bile duct). Also, after cholecystectomy,
stones may recur in the bile duct.