Trails

Q 1. The intervention of the study is to create comparison between clinical efficacy of resting and
antihypersensitive medication. The control in the study focused on checking the patients BP every 30
min for 2hrs.

The population studied involved 138 hypersensitive patients. The patients were in an emergency room
for Veterans Health Services.

The randomisation process used in the study involved the 138 patients. Further, focused on allocating
patients into two groups. The groups included resting and antihypersensitive medication. The analysis
of the groups was done perfectly as it allowed all the participants to get involved in the study. The
conclusion of the study had contribution from all the participants.

Q 2.

The strength of the study involved the use of randomization. The randomisation method was effective
for producing perfect results. In addition, randomisation method makes it possible for the research to
get variable results which enhances the study.

The method and control measures used in the study makes it possible for the researcher to obtain the
right results. The methods used are essential in addressing the trails. Ideally, the methods contributed to
the overall conclusion of the trails that there was no significant difference between resting and
antihypersensitive.

3) Weaknesses of the trial

a) There was no optimal dose timing to check the efficiency of the antihypertensive medication drug.
The working of the drug was only checked after every 30 minutes which is a less time for full working of
antihypertensive drug.

b) Other parameters which can elevate blood pressure of patients were not considered during sampling
and analysis. During sampling, the patients were not asked if they involve in stress related habits like
smoking tobacco or taking alcohol as well as eating more and also of they have any other pre existing
conditions like chronic disorder or diabetes

Q 4.

a) For those in medication group, the number of patients who approached the primary endpoint was
69.1 percent while the number in rest group was 68.5 percent. This resulted in a P= 0.775.
b) In both the rest group and the medication group, the blood pressure change levels had no significance
difference in both SDP and DBP. The P= 0.882 and 0.441 for SDP and DBP respectively.

5) The trial had a successful outcome since there is no significance difference in change level and
decline of BP between the rest group and the medication group. Since the antihypertensive medication
has side effects and there is great concern about its safety the clinical management of patients can
advice the patients to use rest as an alternative for the medication. The rest group will benefit more
from the intervention than the antihypertensive medication group because they will get the same result
for the BP without getting any side effect. If other trials have similar outcome, they should be
reconsidered and safe interventions made.

c) After the stipulated time of 2 hours, there was no statistical difference in the SDP ( P= 0.065) and DBP
(P= 0.032) between the resting and the medication groups.