Capitulo 23 DIAGNOSTICO DIFERENCIAL DAS DEMENCIAS Aquiles Mamftim e Sergio L. Schmidt INTRODUGAO cts pole srl Gens ow mc 51 cong que rjc o funconsnenta dial bs ‘Rae thd coun (aida) A sensncn én ere Thelen conlderado sail cm ue todas as anges that psoas delist premtocae Newe como or Ihecient normal poe nr did em iro nse ‘hd wal (em prj anc capac de core perinrfncons) Awenlldae iene tnd ees canoe pre [Hin scontenan cn intend mr com deb Rao= tals acini prbers gcorer seis aster ron Fornselrag_ sen "Vir ori eta epi ox motion pla is cas do nosso orguismo emcee c perc ns funconalsae, prea tds, gon, site 9 ogi como oy {cdo Annie dens eo Emo proper pre Cx ‘Sr erehecnento elma iflzmert anda no sprestn- ‘Ses concn ahd Cenc dquo proceed ‘vehecinento seem i ean de nate alta ‘pence da programa pend e dar seragbs que ao ‘orrend em leis lar lair, qr eae dt sul ch as ear ty On cope amon a rs afer, em menor gray, dos metanimos de homes O fendmeno do emehecnento ear frente nwo th code pardclrmente portant cm aren, pel rode cates dorm de capac eparaore inital ‘em, alin for 2 pods iuonss arene. Ov nos catsiceepemetere featooeneto ste rs ‘ee contest dente apse erage morals ‘oligea nos cérebro de pcietes porto de doe ‘olegenerathar aoc como eoncnent, ‘Ar reper dee modieages neon na er cog sh podem inlandreamente nv atnds deepen {Esc deerminar que tac extode sige reais pre ‘een dn ot camrertatinents, Cogs fo mo pete per deters fnclonsrneni est do doy [ein bie pa prc, aro ec liner soeacre pros esporaradequdisisslckags ‘stun eterno (Cabral ta 2005) (Otero dein orga atk de ig) en tenes). No inn dss XIX ene queries com sora ge acomtin a fang de mem, compres ¢ ‘compari. Prurormete, a deme forn exh or ‘hanes onctun splopen cindy neh persica. es metic antec, eth ees Eine ports p te sncropnaiges Ene conc senplodo term sc eh guns pari dncnrere plop 1h da anatrnockcn, Moe deters dent ponoe A tralgodoremertn de etipor econ, dese por Cha, ‘etic dudes poorer Ae ‘dost IX, daerbramente dsdemti esa she erogenous pro por ps coo spire ani ratrine peda enon Se Cletni) sao por depurarapalhadaaic e e ‘mtn adres cmon Be fy» depo dente precoe tema rig cm Kexpetin ed nprapeo conte (Ste uma csigtde elton gueo aap {Gener denominadn exten or Bl) eset CGoberaden ace stolen clove por eter am, no nico dtc XX “ntl Seating ice qo pops pre ‘era antl St eet Ccmopasgss crn Re legen array Spee? ‘ila e a reaps de cirnes melireen, ciogur ope com bo ar aks ooo "En or nga posh, ps con qu una pron agrestis de nee etl encom sheraaede ‘eds deisel decaretedo dk mesg (principle fence, econ selene) Outs pombe Chae hero de kt om fortran Adpreio aotr Sd eager cog, resend dhe dea, toa alentndo arts de famore de sto ea ego teen bin copay in mo poet oe deen depress e dia coptn-lra CARACTERISTICAS E DIAGNOSTICO As sndromes demenciss So caracterauae pla presen de dale progrenvo na kano ogni, com mor fe ns pr. ‘kde memes e interlrenca na ate oct © ocpac ‘ae Important alent que o dando da some een[depen quis oer snes Steere ree ee nee es ie eles eee Tepiepeeers enced aren nage ee eee eset can Fan tad Gog Qakeam Beem Dap Ee ee a tr i als digecte dk ees espinal Sane Sae eee ae pe Diecast oem here eee es rime etme pee rd See eer eee Ne poersr ee oe eon a ee a ee eee ge = ae ere Seibert eerie eee See Seas i he et rpranc cece pcr ale rr eee oem eeeemen he chic ge Se Seemed sear ec ree pacers nein seis oe ern pa ren mene fei See eae wake toes ate Sn eet ee aria er eee rae eee ea ree | Quadro 23.1 Caracteristicas de Delirium e Demeéncia Delia Deméncia Trio Dra enanas —Criniea lauante Nonna! Mult tenes, Tard precoce Malo akerada Poco tered Freqdentes Mitrares “Tene ans, Lib Mais presemads Raltramente boa perio sep set et eerie gate eee Setanta sentation heer eee tas eccentric Byala mane tnegm Secinceimemene a ote ca a denna rotator (Simard Ep aeecanae ieee ESS cena gS era nine poem fhe fic geal enero, examet bortras de nero. ea netted ert errr Stace nc gemem a eae rp te te soho eoer et ieee a iereatene ius snares iientebeetemenrent eengaitiae manent eeneame eects sci aoe eel cea aes Eeceieaee moana Laces eres iota aa ae Be Samana eee eerste haters coe ea cio = eeenere comer meer grote Pecorino saeeet eee rtaae So EE eerie acerbic reat Fe emprerarticnt ed Hiden ieemane meta Snip meconium Quadro 23.2 Fraquéncia dos Tipos de Deméncias por Fats Blas Freqitncla dos tipordedeméocl —_—de6S anos + de 6$ anon Downga de Alsheimer 086 5586 Deméncia scar 1886 20% Deméncia Fontotempor) 1256 = Deméncs porcorpanulos 16 208 ‘deLewy Outros 29% 524 / Diag eel ns So Oui measles et ee eee Socal a tn ase ee Sear tales en op, aeeot chap rnle hte ee ees {ADAO imacoai furs deteio degra DAC eae nae pe soins remane Paes Se eee poe ee oe Shope oe ee ce ‘TRANSTORNO COGNITIVO LEVE (TCL) ‘Vira clasificagis foram propose deros terme ues. sos pra eter How Smt ques deeb ue [peciciem on critéros pr dem. Dee eset, Knorr tanto coutve Kre™ (TCL). O anne & ‘arated por moma copii mas ne dese it ‘move tl gle que post conan gn quer de ‘emencia quer de dln. Os eion apes por Pec et 162001) pao ign de aera cess ls so 1 queia de meme prefesivemente confi por um infor smant 2. dt de merino por testes (ca dese tho de sproximadamente 5 deniospdrso aa dames de ontle norma da mesma ade) anges copii gras ‘eras 4 stdaesFrcomal (econeupacona) naa « Saute demencin Dero stores fetesen eal 2001 use etal, 2008) propre ane T — com eompromrtinenta da emia; TCL — com eompro- ‘etic de ips damien TCL — cn composes 1 demi opi Cg, vec ns ‘seats sem comproncdnento dr meat “Canforme set spree nse cpa, des estudos mos ror en Se deserts de mana ete ot portaoves de TCL Garant a, 2002). Ese exo apresen fam tas de omer anl qu ali deo 2596 3 ‘mlorisem torn de [24 15% De tate esto ovo Je prevlnca de TCL na papa gral ia welled diel Us dhogutstas. Aas trae ante efter» nce ‘eds prone dor eteion dogo in TR Tene x ‘ros nsrumento wlzdor na rio ks podemoe car © DMEM (in-Esamc do xed Mea, Teste So Reg, Sa testes saa de Weschler tet de sprezgen soba Rey "Soop", Tal Making Test cena eal No Labo ‘aro de Aalto Near ald Univer do Esa do Rind once GAN GEN, so rotncrement lt “aor exanes computa de wali nepal Exc itbertéio em deo} pean nurpstologs cider: ‘ada pel publics nos ol 1S sor (hex: Cabra, 2005 Sean al, 2000 abe). No abort, loon insoumentoscompuradorand descr em nosso elo (Schmidt e Manes, 2005), como amb estes tradonls ‘lates nearopsengnt addr «norman eh Olver, 199) Neiecontexte,apreentaremos una sso dos ‘chats do grupo do Laborato te Avallagio Newocn ‘aml da ere do Estado do Rn de ira CANCER ‘menor coma Sata Can de Vitine Programa de Pos o em Neurlogia da UFF, demonstra ports Dicics newopatelga pr dag de Te ‘eenihade especie pares gute do TCL fo- ‘am investiga ulead tres instrumentos usados nt clea crop, A ams em 14 nde co icictoptior 68 son O py cos de porters TCL(n 1} concontertn = 35) om ow Eamnedo Eto Momal (MER) ete top sempeno nto dis gros resco fo deo portaders dc Hnsngonsresetrem ior deepen dein nae ‘opti moan acto tadores de DA ae stem plor nos teter de meniia exists (Pate al 1995) ‘Ato ne demi cra sort em soit extend, mar comideramoso concent ds racine scar copia como eno eleva pars steno me then erst: Anda ques rere inp ncn priticy, dev caus singh ete Wanatrn copa le «emda. NEUROPSICOLOGIA, GENETICA E NEUROIMAGEM NO DIAGNOSTICO DIFERENCIAL PRECOCE (x estos de neuibimagen funcional também auam no da aleragtes copra NaDA, cer tpcamen. «ci eg als ent aid a angio e metabo cr ees tempor ou temporopar tals (DeLeon 2001), Resort, Wallet Q009) este154_/ ptin ei drDencie sa pp i eae oT, tds int ab eta ms cheat Seog ce Emin cig tices apache tial cette man medline psercren ‘Smtr inihainenc tomo ecinrpeaes AeteCa on Salutes ns sopua eid eens dpe ‘nite penny oper doc 5 tema que o chat teas depen at eget pein peor paccanmeee Rue Ua {Scenes foyer te ae £4 en opipnecoaa acs eer te copie teas rence ctl ae rupees Cte Roles br Las ees Hc ae ‘Sings mpc erence “Teue Comper nt (Ten tc ra Circspua poe ie nes ealagiodet os poleeeels Octines otyrteiaion erenias Fabre TeLeDA polreeet pratchion ts Seti pur precios eather banat eo trailed comer pan BX Be Lo Ted os depos Totus ipercpgedopeiarcedoneine ron tt dar uaa i fe fone Svcs Tek pros pei esokate pero, glia: gakentrciocestiicranta een tele nene nyseemespees ‘moma Tek cnepecarscs On poe ener Serene chugs dpe petites ae Tel (Cia ess 203): New sein © Dears Cores (rir otal Cardone Riders dae Saou ne bah Gnesi be fap Sans atuzndo em colaboracSo com diversos colegas (entre eles © Dr. ‘ule enfine oD lation Moga asec ea (ies aanrescnindeaaicrere seen BIER Tiocrel ie svck-eedere cee teuesae cinpamu com dpone ie BIBLIOGRAFIA de git ee cat eee naan Se Se ocean Aa RR ge Suis nL ew cg ta ae oe se Arch Neural 199936673680. mens aa fame cate Say ge naif a ripeness a sada Saf in L Sy fe prin epi aoa ttre nee katie ct, Se esearch cient Mar ttt tnt Sones rete sel gd pi Nee Ma gh 5 che at ta, cae, Dek, Gna gate aha ie ee Tecan Face siremuncnnel Nang Ss) rare in dees ay | care | cance OME Make Amb gute “cetacean mae rte | Syicee ere oes | coal hg SEs oe Oa cme aly of by aa ie hes eon of Reng a | catnip Seated patent | apr dase [oer Pye ee 06 camp tase Dh fens ers men oe | rt ec l Dgenmaj, J Shomer amnésticas em deméncte. le: (ed Neal, | ‘Grane, Mar ele), Newrpaalgs Edy So Pala SP De Leo Comi , WalfOT, Tach CY, Def aac aL Peano opie eine orl ay iwi [(U8)FVvre-2-deoey- gluconepotroncemisiontmoprpy (Goce rad casa us sn sie Font ae Ane tte det ‘tor supets Europe scl tay of opto Chora, Newooge Dies the Eley Resta Greap Ne ‘ology 2000545105, Gala Net Gas M,Frienen OV. agi een lenin, ey ug Clin 2005:119-30 Gealy Ct Hoy JB, Hera B, Sundaram M, ep, Sapo Me 1 Lonatal aly ft ety sewropecooglacerial ‘meal changer ia denen the Abney] Clin xp Neoropayetl 18850557696. ‘Gruber Epon RE, Hal C, Cyt Memory mpinent onfie ‘snd cued selective reminding predicts dementia: Newly o0gstsii-32 ich G, Key Kb Cea The 143-3 ban potin in ce Tron id a male or tase peng sneha ie 1 gf Med 1996535934.950, agar K, Petersen RC, Boe BP al MR spectrncopy incom ‘ton dementon Nelo 2005313951998 opp RRs’ te th sot US boos 2002 "Lahde Ancor 202 Latch G, bere Excite font es in ikl Aner “ine Nesopmcolog D9EDS IS tee AG unas Hodes Re a Anche and rcogulon me ‘myo soe eer deat Ipc or Sag ar] Rec 00318160. 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Rie Jano: ior Copia 2008 (promo pers un cca plo CH, Sch SL Copa Daqser EMA Tete dos Cals Ride ani: ltr Copii, 200 (aroado pars no nice plo CH) ‘chi, Minhie AC. Teste computor tno vial (TCA “Bec Her bron “Sl SL Manes AC. Teste computador da mem (TCM. Ride nein Ed. Neuraog, 20050, “chi sy Olea RM. Tete ument de Mma de Temes Ro eens Er Cg 193 ‘Smile SI, Olvie RM, Kae TE, Pgs CC. Theft of and erence gender on finger taping perormnce aye hy ‘hese of am infred igh measrement device. Neuepsye o0;38(5:529-34 ‘Stet aty Olvere ROG Rone FR, Abie Vilgs Yr of Sdednen nd gener on the et Br Does aas0 Leaibtaaay te Sch S, Sider T,Rougt AC, Gy Empl aay ofthe sec steno and sce bhaer heal eae Dupo Dit Danis / si sept a heen ie br sige sas ngs ss ini. Fn ie tn ee eee tr everest sh Di, Sl ch Ft eine Seen ee me Ebene ara sti tn i ba settle eer tat Sie ete Bee vel tReet Se eae epee pps art ee isiae ws coc ce Dang Meow ctmerbs istrict mentees Ferececici wpa Sg A an, tt Fie a pete era Saas