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NGHI£N CøU §ÆC §IÓM H×NH ¶NH CéNG H¦ëNG Tõ HÑP èNG SèNG Cæ
Vµ B¦íC §ÇU T×M HIÓU NGUY£N NH¢N HÑP èNG SèNG Cæ
X¸c ®Þnh yÕu tè nguy c¬ cña héi chøng cung l−îng tim thÊp
sau phÉu thuËt tim më d−íi tuÇn hoµn ngoµi c¬ thÓ
Lª Xu©n D−¬ng
TãM T¾T
Héi chøng cung l−îng tim thÊp (LCOS: low cardiac the mechanical circulatory support for the patients with
output syndrome) lµ mét trong nh÷ng biÕn chøng nÆng high risk.
sau phÉu thuËt(PT) tim, liªn quan ®Õn tØ lÖ tö vong cao Objectives:The aim of this study was to identify the
cã thÓ lªn tíi 38% vµ t¨ng tØ lÖ biÕn chøng. X¸c ®Þnh yÕu preoperative and intraoperativepredictors of low
tè nguy c¬ cña LCOS sauPT tim lµ cÇn thiÕt, ®Ó tèi −u cardiac output syndrome after cardiac surgery with
hãa c¸c yÕu tè nguy c¬, chñ ®éng sö dông c¸c biÖn cardiopulmonary bypass.
ph¸p hç trî tim m¹ch ë bÖnh nh©n (BN) cã nguy c¬ cao. Material and method: we conducted prospective
Môc tiªu:X¸c ®Þnh c¸c yÕu tè nguy c¬ tr−íc vµ sau study description data. Between 12/2009 to 5/2012,
PT cña héi chøng cung l−îng tim thÊp sau phÉu thuËt 124 patients underwent cardiac surgery with
tim më d−íi tuÇn hoµn ngoµi c¬ thÓ cardiopulmonary bypass at central Military hospital
§èi t−îng vµ ph−¬ng ph¸p: Nghiªn cøu tiÕn cøu, 108. The predictors of LCOS weredetermined by
m« t¶, gåm 124BN PT tim më d−íi tuÇn hoµn ngoµi c¬ means of stepwise logistic regression analysis
thÓ t¹i BÖnh viÖn TWQ§ 108 tõ 12/ 2009 ®Õn th¸ng 5/ Results:The overall prevalence of LCOS was 16,9%.
2012. X¸c ®Þnh c¸c yÕu tè nguy c¬ ®éc lËp cña LCOS. The mortality of LCOS was 9,5%. The dependent
KÕt qu¶:TØ lÖ m¾c LCOS lµ 16,9%, tØ lÖ tö vong predictors of LCOS were preoperation cardiac index ≤
trong LCOS lµ 9,5%. YÕu tè nguy c¬ cho héi chøng 2,5 l/min/m2 (OR= 6,4), NYHA class III,
cung l−îng tim thÊp sau PT gåm: chØ sè tim tr−íc PT IV(OR=5,91),intraoperation tranfusion red blood cell
≤2,5l/phót/m2(OR=6,4); NYHA III, IV (OR=5,19); truyÒn ≥750 ml (OR=4,65), the aortic clamping time ≥90 minus
khèi hång cÇu trong PT ≥ 750 ml (OR = 4,65), thêi gian (OR=3,72), PAPS ≥50 mmHg (OR=3,4),
kÑp §MC ≥90 phót (OR=3,72),¸p lùc t©m thu ®éng cardiopulmonary bypass time ≥120 minus (OR 3,22).
m¹ch phæi (ALTT§MP)≥50 mmHg (OR=3,4); thêi gian The independent predictors of LCOS were
tuÇn hoµn ngoµi c¬ thÓ(THNCT) ≥120 phót (OR=3,22). theNYHAclass III, IV, intraoperation tranfusion red blood
Trong ®ã ®é NYHA III, IV; truyÒn khèi hång cÇu trong cell ≥750 and the aortic clamping time ≥90 minus.
PT ≥ 750 ml; thêi gian kÑp®éng m¹ch chñ(§MC) ≥ 90 ConclusionsWe can remove some risk factors of
phót lµ c¸c yÕu tè nguy c¬ ®éc lËp cña LCOS sau PT. LCOS such as the aortic clamping time and
KÕt luËn:B»ng c¸c biÖn ph¸plo¹i bá c¸c yÕu tè cardiopulmonary bypass time(with advancedsurgical
nguy c¬ nh− rót ng¾n thêi gian kÑp §MC, thêi gian techniques) and limit of the indication of intraoperation
THNCT(th«ng qua n©ng cao kü thuËt phÉu thuËt) vµ tranfusion red blood cell canreduce the risk of LCOS
chØ ®Þnh chÆt chÏ truyÒn khèi hång cÇu trong phÉu after operation.
thuËt cã thÓ lµm gi¶m nguy c¬ LCOS sau phÉu thuËt. §Æt vÊn ®Ò
Summary Héi chøng cung l−îng tim thÊp lµ mét trong nh÷ng
Low cardiac output syndrome (LCOS) is one of the biÕn chøng quan träng nhÊt sau PT tim, liªn quan ®Õn
most important complicationafter cardiac surgery, tØ lÖ tö vong cao cã thÓ lªn tíi 38% [3], [4] vµ t¨ng tØ lÖ
associated with a high mortality rate of up 38% and c¸c biÕn chøng vÒ h« hÊp, nhåi m¸u c¬ tim, ®ét quþ
increase complication rates. Identifying the risk factors suy thËn vµ PT l¹i [5]. Ngoµi ra c¸c BNLCOS cã thêi
of LCOS is neccessary to optimize the risks and use gian thë m¸y, thêi gian n»m håi søc, thêi gian n»m viÖn