NAME INDICATION MOA SIDE FFECTS Nursing responsibilities

Generic name: It is used to treat certain Omeprazole interferes with Frequent (7%): Headache. -Give omeprazole before meals,
Omeprazole conditions where there is too gastric acid secretion by Occasional (3%–2%): preferably in the morning
much acid in the stomach. inhibiting the hydrogen Diarrhea, abdominal pain, -Give whole. Do not break, crush,
Brand name: (Zollinger-Ellison syndrome). potassium -adenosine nausea. dissolve, or divide delayed-
Prilosec - Gastric/ duodenal triphosphatase (H + K + -ATPase) Rare (2%): Dizziness, release forms.
ulcers enzyme system, or proton asthenia, vomiting, -Monitor for signs of vitamin b12
- Erosive pump, in gastric parietal cells. constipation, upper deficiency Because drug can
Drug Classification: esophagitis ATPase enzyme responsible for respiratory tract infection, interfere with absorption of
Proton Pump Inhibitor (inflammation in secretion of gastric acid in the back pain, rash, cough. vitamin B12
the esophagus) stomach -Encourage patient to avoid
- GERD alcohol, aspirin products,
(gastroesophageal To patient: ibuprofen, and foods that may
disease) To reduce the amount of acid in increase gastric secretions during
the stomach which will help to therapy.
treat ulcers or sores in the lining
of the stomach or intestine.

NAME INDICATION MOA SIDE FFECTS Nursing responsibilities

Generic name: -It is used in prevention, and Promotes hepatic formation of -Hyperbilirubinemia - Assess Hct, platelet count,
Vitamin K treatment of coagulation factors II, VII, IX, X. (yellow discoloration of urine/stool culture for occult blood.
Hemorrhagic states. Essential for normal clotting of the eyes and skin) - Assess for decrease in B/P,
Brand name: - Antidote for hemorrhage blood. -Cramp-like pain, chest increase in pulse rate, complaint of
Mephyton induced by oral pain, dyspnea, facial abdominal/back pain, severe
anticoagulants. Prothrombin is a vitamin K- flushing, dizziness, headache.
- Used to treat vitamin C dependent protein directly rapid/weak pulse, rash,
Drug Classification: deficiency and delayed diaphoresis,hypotension.
Fat-soluble vitamin. involved with blood clotting. -Assess for positive Homans’ sign,
wound healing. leg pain hemorrhage, edema,
To patient: hemoptysis, dyspnea, or chest pain.
Since the patient was diagnosed
with gastric adenocarcinoma can
affect any part of the stomach
and can cause ulcer which can
lead to internal bleeding. Vit K
will help to reduce internal
bleeding caused by ulcers.

NAME INDICATION MOA SIDE FFECTS Nursing responsibilities

Generic name: -It is used for patient
Tranexamic acid with hemophilia
(bleeding disorder) to
Brand name: reduce or prevent
Cyklokapron, Lysteda hemorrhage.
- used to reduce or
prevent hemorrhagic
Drug Classification: episodes, especially in
Antifibrinolytic the context of
hyperfibrinolytic
disorders.
Inhibit the activation of plasminogen to -Nausea, diarrhea, -Assess blood pressure, pulse,
plasmin, prevent the break-up of fibrin and stomach pain, or and respiratory status as
maintain clot stability. Fibrin, the main discomfort, indicated by severity of bleeding.
protein involved in a blood clot. Tranexamic vomiting chills,
acid works by slowing the breakdown of fever, severe -Assess for thromboembolic
blood clots, which helps to prevent prolonged headache. complications.
bleeding. -Anemia
-Assess for positive Homans’ sign,
To patient: leg pain hemorrhage, edema,
Since the patient was diagnosed with gastric
hemoptysis, dyspnea, or chest
adenocarcinoma can affect any part of the pain.
stomach and can cause ulcer which can lead
to internal bleeding. Tranexamic acid help to
reduce internal bleeding caused by ulcers. It - Caution patient to make
works by blocking the breakdown of blood position changes slowly to avoid
clots, which prevents bleeding. orthostatic hypotension.

NAME INDICATION MOA SIDE FFECTS Nursing responsibilities

Generic name: -For use as an electrolyte Potassium is a major mineral Occasional: Nausea, -Assess for hypokalemia
Potassium chloride replenisher and in the (electrolyte) that is important for the vomiting, diarrhea, (weakness, fatigue, polyuria,
treatment of hypokalemia function of every cell in the body. flatulence, abdominal polydipsia). PO should be given
Brand name: For example, it is important in nerve discomfort with distention, with food or after meals with full
Citrasate, Colyte, Bi- conduction, muscle contraction, and phlebitis with IV glass of water, fruit juice
peglyte kidney function. administration (particularly (minimizes GI irritation).
CONTRAINDICATIONS Potassium chloride works by when potassium
-Severe renal impairment, replacing lost potassium and concentration of greater
Drug Classification: adrenal insufficiency, -For IV infusion only, must dilute
preventing a deficiency. than 40 mEq/L is infused). before administration, mix well,
Electrolyte hyperkalemia. Rare: Rash
supplement infuse slowly. • Avoid adding
To patient: potassium to hanging IV.
 INTERACTIONS Since the patient was taking Hyperkalemia (more
ACE INHIBITORS - may furosemide, sodium chloride is given common in elderly, pts with -Monitor serum potassium
increase serum potassium to counteract the effects of low renal impairment). (particularly in renal
concentration. potassium levels caused by Lasix. impairment).

NAME INDICATION MOA SIDE FFECTS Nursing responsibilities

Generic name: -Used to treat bacterial Inhibits protein synthesis by Frequent: Systemic: -Monitor CBC and culture and
Metronidazole infections of the vagina, interacting with DNA and causing a Anorexia, nausea, dry sensitivity tests if therapy lasts
stomach, liver, skin, joints, loss of helical DNA structure and mouth, metallic taste. longer than 10 days or if second
Brand name: brain and spinal cord, lungs, strand breakage. Therefore, it causes course of treatment is needed.
Flagyl, Noritate, heart, or bloodstream. cell death in susceptible organisms. Occasional: Systemic:
Vandazole Diarrhea, constipation, -Question for history of
-It is indicated to the patient To patient: vomiting, dizziness, hypersensitivity to
Drug Classification: because Infection with H. Since the patient was diagnosed with erythematous rash, urticaria, metronidazole, other
nitroimidazole pylori causes chronic gastric adenocarcinoma with H. reddish-brown urine. nitroimidazole derivatives (and
antibiotic. inflammation and significantly pylori is the strongest known risk parabens with topical).
antiprotozoal, increases the risk of factor for this type of cancer this Rare: Mild, transient
amebicide developing duodenal and medication will help in stopping the leukopenia; -Monitor daily pattern of bowel
gastric ulcer disease and growth of certain bacteria and thrombophlebitis with IV activity stool consistency.
gastric cancer. Infection with parasites. therapy. Monitor I&O, assess for urinary
H. pylori is the strongest problems. Be alert to neurologic
known risk factor for gastric symptoms (dizziness, paresthesia
cancer, which is the second of extremities). Assess for rash,
leading cause of cancer- urticaria. Monitor for onset of
related deaths worldwide. superinfection (ulceration/
change of oral mucosa, furry
tongue, vaginal discharge,
genital/anal pruritus