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FACTORS CONTRIBUTING TO
INTRAUTERINE GROWTH RESTRICTION
IDENTIFICATION OF AT RISK NEWBORN Mother who:
An at-risk newborn is one who:
o who smoke
• is susceptible to illness(morbidity) o have high blood pressure
• Death(mortality) because of dysmaturity, ➢ causing these infants to have an
immaturity, physical disorders, or increased incidence of perinatal
complications during or after birth asphyxia and perinatal mortality when
• In most cases, the infant is the product of compared with AGA infants
pregnancy involving one or more predictable
risk factors Perinatal asphyxia- failure to establish
Includes the following: breathing at birth
• hyperthermia
• maternal use of teratogenic drugs, such as
nicotine, alcohol, antimetabolics,
anticonvulsants, narcotics, and cocaine
affect fetal growth
PLACENTAL FACTORS
• small placenta
• infarcted areas
• abnormal cord insertion
• placenta previa
• reverse end-diastolic blood flow
• thrombosis may affect circulation to the fetus
FETAL FACTORS
• Congenital infections such as TORCH
infections (toxoplasmosis, other, rubella,
cytomegalovirus, herpes simplex virus)
• Syphilis
• congenital malformations
Patterns of IUGR
Intra uterine growth occurs by an increase in cell
number and cell size. If insult occurs early during
the critical period of organ development in the
fetus, fewer new cells are formed, organs are
small, and organ weight is subnormal.