Cellular Respiration

Aerobic and Anaerobic

Metabolism
Glycolysis takes place in the
cytoplasm
 Glycolysis Simplified
(greatly )

If oxygen is available (aerobic), then

pyruvate enters the Krebs cycle

If oxygen is not available(anaerobic),

then pyruvate undergoes fermentation
Aerobic respiration
 Synonymous Terms
• Krebs cycle
• Citric acid cycle
• Tri-carboxylic acid cycle
(TCA cycle)
 Mitochondrial Structure

The Krebs cycle takes place across inner

membrane space (matrix) of the mitochondrion
ElectronTransport
The Role of Oxygen (O2)
Oxygen is the terminal
(final) electron acceptor
 Oxygen is needed
only in the very LAST
step of cellular
respiration!

½ O2 + 2H+ + 2e-  H2O

 Mitochondrial Structure

Infoldings (cristae) increase the area of membrane

surface available for electron transport
 Aerobic Respiration
C6H12O6 + 6O2 → 6CO2 + 6H2O + 38 ATP

 The Krebs cycle and electron transport

take place in the mitochondria
 The Krebs cycle and electron transport
maximize ATP yield
 38 ATP vs. 2 ATP for fermentation
 Anaerobic Respiration
(Alcohol Fermentation)
C6H12O6 → 2 CH3CH2OH + 2 CO2 + 2 ATP
glucose ethyl alcohol carbon
dioxide

Alcohol fermentation takes place in yeast

and some bacteria, and yields only the
2 ATP produced in glycolysis
 Anaerobic Respiration
(Lactic Acid Fermentation)
C6H12O6 → 2 C3H6O3 + 2 ATP
glucose lactic acid

Lactic acid fermentation takes place in

animal cells and some bacteria and fungi;
it yields only the 2 ATP produced in
glycolysis.