Name of drug Mechanism of indication contraindication Adverse effect Nursing responsibility

action
Generic name: Inhibits protein Suppression/ Contraindicated to CNS: Assess deep tendon
hydroxychloroquin synthesis is chemoprophylaxis of patient who has aggressiveness, anxiety, reflexes periodically to
susceptible malaria hypersensitivity to apathy, confusion fatigue, determine muscle
Brand name: organisms by hydroxychloroquin. headache, irritability, weakness . therapy may
plaquenil inhibiting DNA Treatment of severe personality changes, be discontinued if this
and RNA rheumatoid arthritis Who has retinal or visual psychoses occur.
Classification: polymerase. /systemic lupus changes associated with
Anti malaria, erythromatosus quinoline compounds. EENT: Monitor for the
Anti reumatics It has also anti keratopaty, retinopathy, therapeutic
inflammatory tinnitus, visual disturbance effectiveness .
effects
CV: Do not breastfeed while
ECG changes, hypotension, taking the drug without
consulting a physician.
GI:
abdominal cramps, anorexia, Follow drug regimen
diarrhea, epigastric exactly as prescribed by
discomfort, nausea, the physician.

Hematology:
agrunolocytosis, aplastic
anemia, leukopenia,
thrombocytopenia,

Neuro:
neuromyopathy, peripheral
neuritis.
Name of drug Mechanism of indication contraindication Adverse effect Nursing responsibility
action
Generic name: Cell cycle non Alone or with Contraindicated to Respiratory: Monitor blood pressure, respiratory
cyclophosphamide specific alkalytiing other modalities pregnancy or pulmonary fibrosis rate, and temperature frequently
agent chemically in the lactation during administration. Report changes
related to the management of CV:
Brand name: nitrogen Hodgkin’s Contraindicated to anorexia, nausea, Monitor urinary output frequently
cytoxan mustards. Action disease, hypersensitivity to vomiting during therapy. This is to reduce the
mechanism malignant the medicine risk for hemorrhagic cystitis. Fluid
Classifications: unknown but lymphomas , GU: intake should be at least 300ml/day
Anti neoplastic, thought to be the multiple myeloma hemorrhagic cystitis, for adults and 1000-2000 ml/day for
immunosuppressants result of cross , luekemias, hematuria children
linkage of DNA neuroblastoma,
strands , therby by ovarian Derma: Monitor for bone marrow depression .
blocking synthesis carcinoma, and alopecia assess for bleeding ( bleeding gums,
of DNA, RNA and viariety of bruising, petichae, guiac stool , urine
protein . tumour. Endo: and emesis)
associated with gonadal suppression,
increased risk of syndrome of Monitor for increases fatigue,
secondary inappropriate anti- dyspnea, and orthostatic hypotension,
malignancies that diuretic hormone
may be detected Assess nausea and vomiting and also
several years after Metabolic: the appetite of the patient
cyclophosphamide hyper-urecemia
has been Weigh weekly
discontinued.
Monitor BUN, creatinine and uric acid
before and frequently during therapy
to detect nephrotoxicity.

Urinalysis should be evaluated before

initiating therapy to detect changes in
specific gravity indicative of SIADH.
Name of drug Mechanism of indication contraindication Adverse effect Nursing responsibility
 action
Generic name: Decrease Used to treat Contraindicated in CNS: Determine if the
prednisone inflammation severe patients Euphoria , insomia, psychotic behavior, patient is sensitive to
mainly by inflammation , hypersensitivity to vertigo, headache, paresthesia, adrenocorticosteriods
Brand name: stabilizing immune- drug and its seizures.
rayos leukocyte suppression, components, Fungal Monitor patient’s
lysosomal endocrine infection, cerebral CV: blood pressure, sleep
Classification: membrane, disorder malaria, and those hypertension, edema, arrythmias, patter and, and
adrenocorticosteriods suppressing receiving thrombophlebitis, thromboembolism potassium level.
immune Treatment for immunosuppressive
response , metastatic doses together with EENT: Watch for depression
stimulates bone castration live virus vaccines. cataracts, glaucoma or psychotic episodes ,
marrow , and resistant prostate especially during high
influence bone cancer; hormone GI: dose therapy.
marrow and metastatic Peptic ulceration, pancreatitis, GI
carbohydrate prostate cancer. irritation, increased appetite, nausea, Advice patient not to
metabolism. vomiting, abdominal distention stop drug without
prescribe consent
GU: from the physician
Menstrual irregularities, increase urine
calcium level Instruct the patient to
take the drug with
Metabolic: food or milk and to
hypokalemia, hyperglycemia, swallow delayed
carbohydrate intolerance, release tablets whole.
hypocalcemia, weight gain,
masculoskeletal: Advice patient to
growth suppression in children, muscle report any changes
weakness, osteoporosis and or adverse
reactions
skin:
delayed wound healing, acne various
skin eruption
Name of drug Mechanism of indication contraindication Adverse effect Nursing responsibility
action