INTERNATIONAL STANDARD 180 8466-1 1990 (E) Water quality — Calibration and evaluation of analytical methods and estimation of performance characteristics — Port 1: Statistical evaluation of the linear calibration function Contents poe 1B Seep : 3 Syma 7 2 4 Petomance - a a 44 Crocectworina ange, - 3 42. Caomicnandchacnsiool ne mato 4 43 pam cose 7 5 5 como o ao 1 Chole of wring ngs. seen * {52 Cabin and chara of ha mats - 7 53. Eaton stntas Ane A BREE os cesses 8 279INTERNATIONAL STANDARD 180 8466-1: 1850(€), Water quality — Calibration and evaluation of analytical methods and estimation of performance characteristics Part 1: Statistical evaluation of the linear calibration function 1 Scope {tren appa mthac ening venta, Pa ‘hor po of ts iunana Soar a cove the Sa. Inde to iva compa ai vn an at 2 bse (or anaysea uly ino the etter and teton of tae meth av obs peed oy. 2. Definitions Forte pups of hi pa of S06, to oonng dt oreo 21 ansnsicl mathod: Assn} ated composed te ve fr. Wher th procadr and messy inuctons depend on ‘hemrino, se eter te ajo stereo ot ‘ore ete valid for ary analytical metiod recirng cataten 22 caving instruction: Oecrbes he spon to ‘bined by erasing given sander concenvations, x, The Siecle Cibo ran enn sy dhe aoe mathe. “mont Fes the ute of tha meta, these emaatrses prose ‘hein ne era! brat uy eon 280 gute 1 ~ The enorical method omostnon fencers rom th ose wales BY {house ale caiman cto Assay, content ‘argo porta ace ssenrent afte imprest he ‘Soinest vent 25 seidual standard dovetion, The resitual santard ta pcion of cain, ‘tho mare oe wand of avon os eason180 8466-1 1930.6) ‘ge ew cgutan 13 27. coateanta variation of he matod, Vu: Therese 2.8 working ang (of n snc! maod: The inna Beng omraaywanaes ade power he ‘Suny ore concen, The lower poet In of ‘Song eae in of etcton fa ancl mato 29 homagunaiy of variances: Homogenaty of varinces ‘toad tn suo ae tane fensing om est anaes 2.10 sane of he any! method: The slope of ‘eadno no hecogie i oe 2.11_menauring sample ecton sgl: aro which ‘ante dacty sama t the snr of Be Sern ‘equ rapes th arc sol: Coiy, a ‘Sound ena sie ww ntl a enpen hae ‘Shoo sas camps 3. Symbols “ ‘Concannon fhe tan aml. ‘ ‘Supt of he conconton toa, where re Nl 'S0Bie, = 0, 5 Conanuaon of he stacrssamplat ower lel the working anges sana sare ve Exar of tm aaa same sn ij See ne mente ft) = ‘rss ung he cman Wa-e) va. vee 281 Intrmatan vale of th sane concen toro tarda, hing eo Deets of fro or eeon a 8 sevanee i= mr esa sand devon Resa sand devon obtains by nee regen salon eds Sesion tsi by rom Information sae of on anand serie umber of replete on te re anaheed core roots Coneaaton of ti» anal samo, ‘Sloe rom th iron vl» Concanraton of te ans samo, sei tom he ran ran “ote aon ofthe ciinson with fy = N=" dagees of enon an” cones london of Stunts at ca Srucacn wit eres of econ ‘sono lel of Ph Sten dan of he mato4 Performance 41. Choice of working range 2 te practeo oa ete ofthe craton, Troichlon ange or wer, wane wa, ned ecg ra frat ofa wong range shod here oo wo [Ake exablsing the penne wating rang, meses (tse ‘of lott tye ocommanded N= 9) tarda ‘pea dort The concen, ofthe er arpa aon Serbdvananany ove eng ‘evens fecal he lowest a tgs concoe tne a fh whinge ae eens Ten 180 8866-1: 1900161 ie ft vaanoes @ ‘he afc ested Fe fr Scat rao vont won, PG campsted wiht abe aes of he Fee ES ome et en ©) PO > Fy, 4: 9a te ctfornce betwen the 1 the itranen between she vince sfc he Peary wring ong el be aoe ra ar Oe {erence bono he varanasi oun ob mm oh 282150 £466-1 1890} 429. Tart fortinaasey2 68 ft eration dita with the cloud open ine. Ay ntnary is oun fm eg 2 7234656789 gure 2 — Graphic inorty check nh sn ary ee nt ta nd Dee =a, W315, DesreeotHeedom: f= 08% ate varie ofthe norte cal etn#2 fesubined 0 Pein oreo amine or sgn ch “he te ae PG rend forthe Fart i eee fom saison One Boson 45) 196 < Fhe nn ner etraon uncon doe ot 1) FPG > F:Thewerking ange souk be duced a8 ‘Satta! wang the orn ealoraton reo 42. Caloraton a characteratos ofthe method ‘ce ayn ascrdence eh the spe ote rcs eto oda ob ton WW = 10) earned ‘Thatun dataset, conning fe waves ofan aed ‘adie er ngrasan wyotin the eters “hd te cltatn uncon ic donot tem Co ‘Slovn fovane the snot sae an nceandent ‘SSR Sete neon wae ya pendent orale ‘Roig nrocovd om he mesures not aed In telaarsmunes Fe fe opesson 7 “sar ears action gen by aauton yrenbe 6 “Te sonore ae ota rom equations snity (oe of ae ettraionfuetan anor ha oa 7 Lan‘The concern of narod sae bine 1) tam he mare vay, 103% ‘hear cig song toaie? ow the saya! arr a corto the urease Semon ce are en ce of y| 180 8486-1: 190) ‘bration Se. Between tweze path he Yue calracon fan ‘Son canbe expec’ wn vaghtcare ll fe es nd ‘Sodas tal ='t “a rine by Stent oto ‘especove peo poten igure 9. The ean oe ‘entice ons re en by saustion 21 A= Ps vee =\ G y anon (12) indenter tat the Eanfsane inert VE) trace teenie vate hs ge goes yh atl cut Students ettaon Te magna of ‘ELE ain ders byte rent eps 288 xe ¥ band and single ante rat with es180 8466-1:1990(€) ‘heeresl, ta man ofthe inermaton ves f wel ‘Sony nds ‘Thestanard devon ofthe eed ace gunn (3 For tw comonizan of irnt stndaend eral Evbeceew wenby gua 5 Example ‘ephemeris deamination fit esata camo Ihe carn and te sabravert exertion aa 54. Choice of working range 5.11 Tasting he homogenay ofthe variances" conning ne Fiabe = fa = 9-1 = from ota vasnoe and aoe 99: 090) = 5.35 ‘een ass may be partores “Table 3 ~ Data shat fr the clan of NOs 1 “i x na | T T var | [om fu [vm | |e | om [7 | ae A 2 [oe [em Pee SE OS ‘Tuble¢— Datasheet or the analysis of variance. Object: nit 72 les) ben len len en ee en = te ore o [oi | ow [am | om | amo | ow [oe [ar we =| ex [va tae [sam [same [sae [san | ame [1am [aoe “7 Formas ct umpc mano nt ban nian ot aos, whut any, Th sons fate 285,B12 Teeting teary y= 00188 + 262 ~ 900 Gh dounon of = DAE 2 mal 5 = 0008 21 85.2 frcunton pects) {he vances 05" faoeenmton dos ot ned aS {Stadia Te ona esate uncon ov ot oo Stent mer ssenment 9 hecabaten neon 152 Calibration and characteristics of the method ‘egeson ae ties, clon fonton ‘a te 80 66-1: 1990(€) crage pen by eget (re . 3° Get tranaon) Te anecsrentor comin! ing ‘cinon 2 win acontdence ston 3 yi; 080) 21 Uh na aT reat re noun ne ‘Tear et, cceton a6 F~ be = 07282 ~ 29782 x 027 = 0018 at of EE ama ‘Te eatin fr te salt nas gen by eon) caste an i cased om fa aa * + (ooo «20/2, 1, Reet ores (roses ami 7> ase = (020 £ 0.0061 mon ‘Thur me ous sls of th concenttn can be expec vila 0) <0 al wi ertaee 532, Repsces anahie For tres repiateceemintoy she ancl matod gave the bomaton vies OBA Og an Calesason of he ans e: 26 00 2. > = (mera 3 tee) ‘Thus he me sale of the cancion can be enpeced seen OT cr <0 mgt wi conta a [ow | eae 7 | os | one am | ome 286 7130 9486.1 1690 Annex A (informative) ‘estantndcomparton of rae pecs An pts tostunderaeoion, Vom Waser SD, (3, 574 (2) Mme, J. The tito ane af experimen, Iterzonce Pub, J, Wy & Son (86, Naw York Fa) Goro @, Standen of quntae aril rocetes, Z Anal Chem 275 (978, po. 10. 15) Gna, UN, LJ. and Stan K, Fema tabi fathers ats, nd Eon, Spigr Vale (E66) Sern, keto New Yor (6) Sac, L Mato for sta wali, dt Eton, Sanngr Vere. (1571, Ban, Heda, New Yor 181 Scere, Stein chica nal, VEB Vg fr Guneoinsvce (96), Lla acim R, Eluson of 800-suton ses ~ Pasantaon os comput poem, Vam Wasser 8 (182), pp 7328, Commins og tome, Steve apataude Fenloatin der mesures, ome 2 Maat, (57), pp. 57 8 287INTERNATIONAL STANDARD 180 8466-2: 1993 (E) Water quality — Calibration and evaluation of analytical methods and estimation of performance characteristics — Part 2: Calitration strategy for non-linear second order calibration functions Contents . 1 Scope 1 2 Symbous 4 3 Partoemanee 2 34. Choice of working range 2 412 Test forthe homogeneity af the variances 2 33, Measurement 3 4 Estimation cf the polynomial coefficients 3 5 Pexermence characterises ‘ 5.1 esicual standard deviation ‘ 52 Senstity of the anvil procedure 5 153 Standard deviation of the precede 5 5.4 Folate standard deviation ofthe procedure 5 © Araiysis of a sample 5 6.1 Gonera considerations 5 62 Test for minima ot masime 5 3. Cleustion ofthe most probable concenvation 6 6.4 Precicton tora of the aaiscal rest (se figure 1) ‘ 7 bample 7 7 7.4 Gstraon, petomence cheracteriticn, evaluation 7 72 Sngle measurement analysis 8 Annexes A Fable 89 %) 0 B_Bilograhy oR 288