1.

Differentiate and discuss Peptic Ulcer Disease and Gastritis (Include all from its area of
affectations, Etiology and Management). 

Peptic Ulcer Disease (PUD) is characterized by GI mucosa erosion caused by the digestive action
of HCl acid and pepsin. Ulcers can form in any part of the GI tract that makes contact with
gastric secretions. After surgical procedures, this includes the lower esophagus, stomach,
duodenum, and the margin of a gastrojejunal anastomosis. Antibiotics, Proton Pump Inhibitors,
and Cytoprotective Drug Therapy are used to treat Peptic Ulcer Disease. Peptic ulcers develop
only in an acid environment. Infection with the bacterium Helicobacter pylori is the most
common cause of peptic ulcers. Gastritis, on the other hand, is one of the most widely known
digestive problems. Gastritis is an inflammation of the gastric mucosa. Gastritis can be acute or
chronic, widespread or confined. Gastritis is caused by a breakdown in the normal gastric
mucosal barrier. Usually, this mucosal barrier helps protect stomach tissue from the corrosive
action of HCl acid and pepsin. Gastritis can be caused by drugs and diet, or by irritation caused
by excessive alcohol use, chronic vomiting, stress, or the use of certain medications such as
aspirin.