Professional Documents
Culture Documents
by:
Sieras, Jasmin C.
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TABLE OF CONTENTS
I. Introduction..................................................................................................3
II. Anatomy and Physiology.............................................................................................
III. Pathophysiology...........................................................................................................
IV. Medical Management...................................................................................................
V. Diagnosis......................................................................................................................
VI. Procedure Proper (with Instrumentation) ..................................................................
VII. Roles of Circulating and Scrub Nurse .......................................................................
VIII. Nursing Management.................................................................................................
a. Nursing Care Plan
i. Pre-Operative....................................................................................................
ii. Intra-Operative..................................................................................................
iii. post-Operative..................................................................................................
IX. Pharmacology............................................................................................................
i. Pre-Operative...............................................................................................
ii.Intra-Operative.............................................................................................
iii. Post-Operative...........................................................................................
X. Bibliography ..............................................................................................................
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INTRODUCTION
Throughout 1998 and 2010, the incidence in the United States was predicted
to be over 27,000 instances. The majority of cases involved infants (under the age of
one year) (36 percent ). In children, the most common reason for nephrectomy was
benign problems (58.8%–73.8%), such as ureteropelvic junction blockages (UPJO),
multicystic dysplastic kidney (MCDK), and ureterocele. In Saudi Arabia, there are
just a few studies on nephrectomy in children. Only two research have addressed
the topic of nephrectomy in children to our knowledge. Only two out of 71 children
diagnosed with nephrolithiasis between 1982 and 1991 required nephrolithiasis
surgery, according to Al-Rasheed et al. The other study, on the other hand, looked at
the indications for nephrectomy in adults. As a result, the rationale for nephrectomy
and the outcomes in the Saudi population are not well understood. The goal of this
study was to assess the indications for nephrectomy in children in Riyadh, Saudi
Arabia's King Fahad Medical City (KFMC).
Kidney illnesses, particularly End Stage Renal Disease (ESRD), are now the
Philippines' seventh largest cause of death. Every hour, one Filipino, or around 120
Filipinos per million population, suffers chronic renal failure. Approximately 1.1
million people worldwide are on renal replacement treatment, including over 5,000
Filipino patients undergoing dialysis. According to reliable predictions, the number of
these patients will double in 2010.
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II. ANATOMY AND PHYSIOLOGY
There are two kidney which lie retroperitoneally in the lumbar area. The right kidney
is lower that the left due to displacement by the liver.
Connective tissue anchors the kidney to surrounding structures and helps maintain
their normal position.
Each kidney is bean shaped and measures approximately 11cm x 6cm x 3cm and
weighs 120-170gram. The kidneys are enclosed by a fibrous capsule and the
parenchyma consists of a cortex and medulla. Within the medulla approximal 80-18
triangular structures called renal pyramids are found, and the base of these pyramid
renal papillae are directed toward the center of the kidney. Together the cortex and
renal pyramids constitute the parenchyma of the kidney and structurally the
parenchyma of each kidney consist of approximately 1 million nephrons which are
the functional units of the kidney.
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Renal Blood Supply
The kidneys receive their blood supply from the renal arteries which branch to
the left and right from the abdominal aorta. This blood supply to the kidney is equal
to 21% of cardiac output and 99% of the cardiac output returns to the general body
circulation via the renal vein. The remaining 1% undergoes further processing in the
nephron resulting in urine.
The Nephron
The function units of the kidney are the nephron, and each nephron contains
two components:
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III. PATHOPHYSIOLOGY
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IV. MEDICAL MANAGEMENT
Nonsurgical treatments
Small kidney cancers are sometimes destroyed using nonsurgical treatments, such
as heat and cold. These procedures may be an option in certain situations, such as
in people with other health problems that make surgery risky.
Kidney cancer that comes back after treatment and kidney cancer that spreads to
other parts of the body may not be curable. Treatments may help control the cancer
and keep you comfortable. In these situations, treatments may include:
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Immunotherapy. Immunotherapy uses your immune system to fight
cancer. Your body's disease-fighting immune system may not attack
your cancer because the cancer cells produce proteins that help them
hide from the immune system cells. Immunotherapy works by interfering
with that process.
Clinical trials. Clinical trials are research studies that give you a chance
to try the latest innovations in kidney cancer treatment. Some clinical
trials assess the safety and effectiveness of potential treatments. Other
clinical trials try to find new ways to prevent or detect disease. If you're
interested in trying a clinical trial, discuss the benefits and risks with your
doctor.
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V. DIAGNOSIS
Once your doctor identifies a kidney lesion that might be kidney cancer, the
next step is to determine the extent (stage) of the cancer. Staging tests for kidney
cancer may include additional CT scans or other imaging tests your doctor feels are
appropriate.
The stages of kidney cancer are indicated by Roman numerals that range from I to
IV, with the lowest stages indicating cancer that is confined to the kidney. By stage
IV, the cancer is considered advanced and may have spread to the lymph nodes or
to other areas of the body.
Severe trauma
Injured patients rarely require laparotomy solely for the treatment of renal injury. With
the broad success of nonoperative management of solid organ injury, those patients
who undergo laparotomy tend to be more seriously injured and in need of more
aggressive interventions. Patients who require nephrectomy after trauma tend to be
the most severely injured and hemodynamically unstable, and warrant nephrectomy
as part of the damage control paradigm in order to optimize the opportunity for
survival.
Renal Cancer
Renal cancer accounts for about 5% of all cancers in the United States (American
Cancer Society [ACS], 2015), where the incidence of renal cancer at all stages has
increased in the past two decades. The incidence of renal cell carcinoma is higher in
both men and women with an increased body mass index. Tobacco use continues to
be a significant risk factor (see Chart 54-3). American Indians and Alaskans have a
higher mortality rate from renal carcinoma compared to other races and population
groups. The most common type of renal carcinoma arises from the renal epithelium
and accounts for more than 85% of all kidney tumors (ACS, 2015). These tumors
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may metastasize early to the lungs, bone, liver, brain, and contralateral kidney. One
quarter of patients have metastatic disease at the time of diagnosis. Although
enhanced imaging techniques account for improved detection of early-stage kidney
cancer, it is unknown why the rate of late-stage kidney cancers is high.
Nephrotic Syndrome
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increasing the production of albumin, it cannot keep up with the daily loss of albumin
through the kidneys.
VI. PROCEDURE
After general anesthesia is administered, a urinary catheter and orogastric tube are
placed. The patient is placed in a 45° modified flank position with the top of the iliac
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crest at the top of the kidney rest and the table flexed. The arms are typically taped
over a folded pillow, although an armrest is satisfactory. The patient is then securely
taped to the operative table to allow banking of the table during surgery. All
appropriate areas are padded to include the axilla, knees, elbows, and ankles. A
wide sterile preparation and drape is performed in the event that open conversion is
necessary. Pneumatic compression devices to the lower extremities help prevent
thromboembolic phenomena.
The initial 10-mm trocar is placed under vision at or near the umbilicus for both left-
sided and right-sided procedures. Subsequent trocars are placed under vision with
the 10-mm laparoscope in the umbilical trocar. For left-sided tumors, a 5- to 12-mm
trocar is placed lateral to the umbilical port at the edge of the left rectus abdominus
muscle. Finally, a third 5-mm trocar is placed midway between the xiphoid and the
umbilicus. For right-sided tumors, the 5- to 12-mm trocar is placed midway between
the xiphoid and the umbilicus, and the 5-mm trocar is placed lateral to the umbilical
port at the edge of the rectus. If necessary, an additional 5-mm trocar is placed
laterally at the anterior axillary line, below the ribcage for liver retraction. The first
image below depicts trocar placement for the left-sided procedure; the second image
shows placement for the right-sided procedure.
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Several scenarios call for different port placements. The first is in the presence of
prior abdominal surgery when the initial ports need to be adjusted to allow for lysis of
adhesions. This varies with each patient and challenges even the most experienced
laparoscopist. The next scenario involves patients who are obese and in whom port
placement as described would complicate lateral and superior dissection. Therefore,
in these patients, all ports are moved laterally as needed to allow better purchase of
instruments for dissection. Finally, in patients who are very tall, move ports superiorly
for similar reasons.
The following description of LRN is for a right-sided procedure; variations for a left-
sided approach are provided.
The lateral line of Toldt is identified and incised with either the harmonic scalpel or a
hook electrode approximately 1 cm from the colon. At this point, care is taken not to
allow dissection to stray too deep. Only the thin layer of peritoneum over the anterior
surface of the kidney is mobilized from the iliac vessels to the hepatic flexure of the
colon (see image below). If the dissection is too deep, the Gerota fascia is entered
and the bowel mesentery is more difficult to roll medially.
This plane is bluntly dissected by dividing the colorenal ligaments until the colon has
rolled medially. The 5-mm suction irrigator is particularly useful in this dissection.
Small vessels that are encountered are either cauterized or clipped with a 5-mm clip
applier. An alternative is to use either the harmonic scalpel or the LigaSure system to
control these vessels. Remaining in the correct plane between the colonic mesentery
and Gerota fascia is important. Care should be taken to avoid entering the bowel
mesentery, as hemorrhage would ensue. Once the colon has rolled medially, the
duodenum is rolled medially. This allows identification of the inferior vena cava. To
fully visualize the upper pole of the right kidney under the liver, dividing the right
triangular ligament and part of the anterior coronary ligament is usually necessary.
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For a left-sided LRN, the procedure begins in similar fashion at the line of Toldt. The
phrenicocolic, splenocolic, and splenorenal ligaments at the splenic flexure of the
colon are divided to allow the upper pole to drop into view.
The correct identification of the ureter and gonadal vessels is one of the crucial steps
for a successful LRN. Understanding the relationship of these structures at various
levels aids in this dissection. At the level of the lower pole of the kidney and proximal
ureter, the gonadal vessels are medial to the ureter. As they proceed inferiorly, they
cross the ureter and course laterally as they exit the internal inguinal ring.
Understanding this relationship is important for correct identification of the ureter and
ease of subsequent identification of the renal hilum.
Additional methods to help identify the ureter include pinching with atraumatic
grasping forceps to observe peristalsis and noting the color differences between
structures. Generally, the gonadal vein appears blue, while the ureter appears white.
If neither structure is identified, it is occasionally necessary to begin the dissection
medially along either great vessel and to extend laterally on top of the psoas until the
ureter or gonadal vessels are identified.
Once the ureter and gonadal vein are identified, the next step for a right-sided LRN
is following these structures superiorly to identify both the lower pole of the kidney
and the renal hilum. This is accomplished by lateral retraction of these structures
with the left hand using the grasping forceps or the 5-mm suction/irrigator and
dissecting with the right hand using the harmonic scalpel or LigaSure.
The branching of the right gonadal vein from the inferior vena cava is controlled with
two 5-mm clips on either side and divided. The distalmost aspect of the right gonadal
vein can be divided, if necessary; however, leaving the ureter intact to provide
inferior retraction during the remainder of the nephrectomy is important. For a left-
sided LRN, the gonadal vein and the ureter are again used to identify the renal hilum
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by dissecting superiorly. Following the gonadal vein leads the surgeon directly into
the left renal vein. The branching of the left gonadal vein is double clipped and
transected, if necessary, for retraction or hilar dissection.
At this point in the procedure, the lower pole dissection is easily performed. The
surgeon uses the left hand to retract the kidney anterolaterally, and attachments
between the lower pole and the psoas muscle or the posterior body wall are taken
down. During this portion of the procedure for a right-sided LRN, the placement of a
fourth 5-mm trocar for liver retraction is usually unnecessary. However, once the
surgeon proceeds to the right renal hilar dissection, this additional trocar placement
may be necessary. This can be placed at the anterior axillary line subcostally or in
the midline superior to the upper 5-mm trocar. A 5-mm laparoscopic snake retractor
is introduced into this trocar, and the liver is retracted superiorly.
Once the ureter and gonadal vein are secure and the inferior pole of the kidney is
dissected free posteriorly, proceed with the renal hilar dissection. The left hand, once
again, is used to hold 5-mm grasping forceps to provide lateral and superior
retraction of the kidney. The right hand is used to divide the tissue planes gently until
the renal vein is identified. Small lymphatic channels can be controlled with either
clips or cautery.
If lateral retraction proves difficult, introducing a large silk suture on a Keith needle
through the patient's flank is useful. This is then hooked around the ureter, and the
needle is passed outside the body. The suture is secured with forceps to tent the
ureter against the interior body wall; this provides excellent lateral retraction and
frees a hand to aid in the hilar dissection. On the right side, the renal hilar dissection
is slightly easier because the renal vein has no branches. This is dissected
circumferentially until enough of its length is free to allow division with the
laparoscopic EndoGIA stapler with a vascular load. The renal artery posterior to the
renal vein is identified and dissected in a similar fashion. Dividing the artery first is
customary.
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For a left-sided LRN, dissection proceeds in the same manner until the renal vein is
encountered. The gonadal vein has already been transected, but the adrenal and
lumbar veins must be identified. Once these 3 branches are visualized and
controlled, the remainder of the vein is dissected circumferentially, and the artery is
identified just posterior to the vein.
The authors' approach is to use a stapler to divide the renal artery and then the vein
although most surgeons clip and divide the artery first. This stapler applies 3 rows of
titanium staples on either side of a divided vessel and is very effective in controlling
the hilar vessels. One caveat is to keep the vessel clamped in the stapler for at least
10-15 seconds prior to deploying the staples. This allows for the tissue to release
third-space fluid and to become thinner, resulting in a better seating of the staples.
The renal artery and vein may be stapled en bloc, when necessary. [14] Although
this is not advocated for routine use, the authors feel it is reasonable in lieu of open
conversion if a complex or bleeding hilum can be controlled in this manner.
No arteriovenous fistulas have been reported in humans when the stapling device is
used. Historical reports of arteriovenous fistula seem to have occurred mainly in the
setting of an inflammatory process involving sutures. The 3 rows of titanium staples
likely confer an advantage to sutures, although the authors would still exercise
caution in the setting of an inflammatory renal condition. After the hilum is taken,
leaving the closed stapler in its trocar and using this instrument to bluntly dissect the
medial portion of the upper pole can be useful. This large instrument provides
excellent purchase and bluntly dissects tissue effectively.
If an adrenalectomy is not indicated, the surgeon bluntly dissects along the plane
between the adrenal gland and the superior pole of the kidney. If small vessels are
encountered in this fatty plane, they are divided easily with various cautery devices.
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Remaining renal attachments
All that should be left holding the kidney in situ is the lateral attachments to the body
wall, the superior attachments lateral to the adrenal gland, and the ureter. These
attachments are dissected free with a combination of sharp and blunt dissection
using the cautery device of choice, with the grasping forceps for counter traction.
The ureter may be divided before or after the lateral attachments are completely
freed. The authors typically place two 5-mm clips on the ureter and transect it. The
specimen is now completely dissected and placed on either the liver or the spleen in
anticipation of its removal.
Specimen removal
The 15-mm EndoCatch is used for intact kidney removal. Under vision, it is placed
through a small opening in the peritoneum at the incision site. (A seal may then be
created around the instrument shaft to allow for pneumoperitoneum by placing the
adjacent abdominal wall tissue in an Allis clamp or towel clip.) The bag is advanced
until it springs open. Grasping forceps are used to place the kidney into the bag
under direct vision. Visualizing completely around the ring of the EndoCatch opening
to ensure that no bowel is being included with the specimen is important. The string
is detached and pulled so that the bag closes, and the ring that held the bag open is
retracted under direct visualization.
The opening of the bag is now brought out through the incision site. The incision is
extended to approximately 5 cm, and the fascial incision is extended to
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approximately 7 cm. This usually allows easy removal of most kidneys. If necessary,
the incision can be extended. Once the kidney is removed, the fascia is closed with a
running No. 1 PDS suture. Pneumoperitoneum is reestablished, and the renal fossa
and inferior and superior extent of the resection are examined for hemorrhage.
Although more tedious than an electric morcellator, this technique results in bigger
pieces that allow for better pathologic diagnosis and staging. The LapSac is the
preferred bag for tissue morcellation because it has been shown in animal studies to
be impermeable to cells and its nylon reinforced plastic is more durable and resistant
to perforation. Morcellation provides the advantage of improved cosmesis and
decreased incision-related morbidity (eg, hernia, adhesions) and is safe when
performed with the proper technique and bag. To date, no cases of port-site seeding
clearly related to the morcellation process have been reported with the use of the
LapSac.
Closure
Once the specimen is removed, the umbilical fascia closed, and pneumoperitoneum
achieved, the renal fossa and inferior and superior extent of the dissection are
examined for hemorrhage. Pneumoperitoneum, once again, is decreased to 5 mm
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Hg for a few minutes and hemostasis is confirmed. The 5-mm trocars are removed
under laparoscopic vision. Finally, the last 10-mm trocar is directed into the
corresponding upper quadrant, and as much carbon dioxide as possible is vented.
The trocar is then removed with the laparoscope inside to prevent bowel entrapment.
Finally, all skin edges are approximated with Monocryl suture, skin staples, or
Dermabond adhesive.
Circulating Nurse
One sort of operating room (OR) nurse is a circulating nurse, who operates on
the perimeter of the operating room, monitoring patient care, assuring sterility, and
keeping track of equipment and sponges. Perioperative nurses also assist patients in
preparing for surgery and provide important care and monitoring after their
procedures are completed. Scrub nurses are just as crucial as the surgeons who do
the cutting.
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Make sure theater is clean •
Arrange furniture according to use •
Place a clean sheet, arm board (arm strap) and a pillow on the OR table
Provide a clean kick bucket and pail
Collect necessary stock and equipment
Turn on aircon unit • Help scrub nurse with setting up theater
Assist with counts and records
During Operation
Remain in theater throughout operation Focus the OR light every now and
then Connect diatherapy, suction, etc.
Position kick buckets on the operating side Replenishes and records sponge/
sutures
Ensure theater door remain closed and patient’ s dignity is upheld
Watch out for any break in aseptic technique
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End of Operation
After an Operation
Observes the surgery and surgical team from a broad perspective and assists the
team in creating and maintaining a safe and comfortable environment for the patient.
Assesses the patient's condition before, during, and after the operation to ensure an
optimal outcome for the patient that must be able to anticipate the needs of the
surgical team with other care providers necessary for the completion of surgery
Scrub Nurse
A scrub nurse is a particularly trained nurse who works in the operating room
with surgeons and the medical team. Scrub nurses are important members of the
surgical team because they provide support in the operating room as well as patient
care outside of it. Nursing occupations are continually expanding due to the growing
demand for these critical health care workers, and they may be quite demanding but
also very rewarding. Some scrub nurses, particularly experienced scrub nurses who
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are knowledgeable with a wide range of operations, become highly sought-after
members of surgical teams.
Before an operation
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Prepares sutures and needles according to use
During an operation
End of Operation
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Prepares the patient for recovery room.
Completes documentation.
Hand patient over to recover room.
• Works directly with surgeon within the sterile field, passing instruments, sponges
and other items needed during the procedure. Members of the surgical team who
prepares and preserves a sterile field in which the operation can take place.
Responsible for the sponge counts, the blades and needles and instruments check
throughout the operation. Has a job requiring anticipation, quick reaction and
conscientious observation as well as knowledge of anatomy and of operative
procedures.
ii. Intra-Operative
Maintain patient in the comfortable position throughout the surgery
Monitor patient vital sign to have a baseline data
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iii. Post-Operative
Provide routine postoperative care
Frequently assess urine color, amount, and character, noting
any hematuria, pyuria, or sediment. Promptly report oliguria
or anuria, as well as changes in urine color or clarity. Preserving
function of the remaining kidney is critical; frequent assessment
allows early intervention for potential problems.
Note the placement, status, and drainage from ureteral
catheters, stents, nephrostomy tubes, or drains. Label each
clearly. Maintain gravity drainage; irrigate only as ordered.
Maintaining drainage tube patency is vital to prevent potential
hydronephrosis. Bright bleeding or unexpected drainage may
indicate a surgical complication.
Support the grieving process and adjustment to the loss of a
kidney. Loss of a major organ leads to a body image change and
grief response. When renal cancer is the underlying diagnosis,
the client may also grieve the loss of health and potential loss
of life.
Provide the following home care instructions for the client and
family.
a. Teach the importance of protecting the remaining kidney by
preventing UTI, renal calculi, and trauma.
b. Maintain a fluid intake of 2000 to 2500 mL per day. This
important measure helps prevent dehydration and maintain good
urine flow.
c. Gradually increase exercise to tolerance, avoiding heavy lifting
for a year after surgery. Participation in contact sports is not
recommended to reduce the risk of injury to the remaining kidney.
Lifting is avoided to allow full tissue healing. Trauma to the
remaining kidney could seriously jeopardize renal function.
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d. Teach care of the incision and any remaining drainage tubes,
catheters, or stents. This routine postoperative instruction is vital to
prepare the client for self-care and prevent complications.
e. Instruct to report signs and symptoms to the physician, including
manifestations of UTI (dysuria, frequency, urgency, nocturia,
cloudy, malodorous urine) or systemic infection (fever, general
malaise, fatigue), redness, swelling, pain, or drainage from the
incision or any catheter or drain tube site. Prompt treatment of
postoperative infection is vital to allow continued healing and
prevent compromise of the remaining kidney.
IX. PHARMACOLOIGY
i. Pre-Operative
ANTICHOLINERGICS: glycopyrrolate (robinal) decreases
respiratory secretions.
ANTIANXIETY: lorazepam (ativan) reduces anxiety
HISTAMINE-2 RECEPTOR ANTAGONIST: cimetidine (Tagamet)
decreases gastric acidity and volume
NARCOTICS: Demerol (meperidine) decreases the amount of
anesthesia needed to sedate the client.
SEDATIVES: midazolam (versed) promotes sleep or conscious
sedation and decrease anxiety
ANTIBIOTICS: kanamycin (kantrex) destroy enteric microorganism
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ii. Intra-operative
iii. Post-operative
Epidural analgesia is considered as most effective for the
treatment of postoperative pain after open nephrectomy, but after
laparoscopic operation parenteral and enteral opioids combined
with paracetamol (acetaminophen) usually offer adequate
postoperative pain relief. However, the need for opioids
postoperatively may be high and side effects, such as sedation and
nausea, are common. On the other hand, epidural analgesia has
some contraindications and risks for serious complications.
Nevertheless, inadequately treated acute postoperative pain is
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considered as one of the main risk factors for persistent
postoperative pain.
X. BIBLIOGRAPHY
https://www.medscape.com/answers/445458-186342/what-are-the-steps-to-
perform-a-transperitoneal-laparoscopic-radical-nephrectomy-lrn
https://www.mayoclinic.org/tests-procedures/nephrectomy/about/pac-
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20385165#:%7E:text=Most%20often%20a%20nephrectomy%20is,diseased
%20or%20seriously%20damaged%20kidney.
tourism.com/nephrectomy/philippines/
Patard, J. J., Shvarts, O., Lam, J. S., Pantuck, A. J., Kim, H. L., Ficarra, V., Cindolo,
L., Han, K. R., De La Taille, A., Tostain, J., Artibani, W., Abbou, C. C., Lobel,
B., Chopin, D. K., Figlin, R. A., Mulders, P. F., & Belldegrun, A. S. (2004).
2181–2435. https://doi.org/10.1097/01.ju.0000124846.37299.5e
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