Nama : Niken Ika Wulandari

NIM : N011211091
Kelas : Biofarmasetika C

Drug Log P Log D Log D

7.4 5.5
Estazolam 3.25 2.50 2.50

Chlordiazepoxide 2.16 2.36 2.36

Midazolam 3.93 3.35 2.80

Clonazepam 2.34 2.53 2.53

Lorazepam 1.93 1.90 2.30

Alprazolam 2.50 2.63 2.63

Diazepam 2.91 2.92 2.91

Clobazam 1.69 2.26 2.29

Tabel 1. Turunan benzodiasephin

Drug Log P Log D Log D

7.4 5.5
Fluvoxamine 3.11 1.08 0.01

Escitalopram 2.51 1.27 0.34

Duloxetine 3.73 2.16 1.00

Fluoxetine 4.09 1.75 1.18

Sertraline 4.81 3.14 2.13
Amitriptyline 4.92 2.96 1.73
Phenelzine 1.14 0.51 -1.19
Venlafaxine 2.91 2.80 0.16
Tabel 2. Golongan antidepresan