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Volume 600 / Number 8 / 15 April 2022
Editorial
1811 Elevating physiology: Griffith Pugh on the limits of human
performance and survival
Mike Stembridge, Philip N. Ainslie and John B. West
Perspective
1815 Therapeutic effects of recreational exercise on skeletal
muscle ageing – how much is enough?
Davis A. Englund (see Soendenbroe et al. p 1969)
Translational perspective
1817 Assessing proteinuria: value added from a mathematical
model
Alan M. Weinstein (see Edwards et al. p 1933)
Journal club
1819 Sweet release – intravenous, not oral, glucose
administration increases microvascular blood flow
Jeremy N. Cohen and Jennifer A. Wilkinson
1821 Could angiotensin-II induced T-cell senescence exacerbate
age-related vascular dysfunction?
Ravinandan Venkatasubramanian, Sophia A. Mahoney
and Zachary S. Clayton
Topical reviews
1825 Hepatic stellate cells in physiology and pathology
Dakota R. Kamm and Kyle S. McCommis
1839 Ageing and exercise-induced motor unit remodelling
Eleanor J. Jones, Shin-Yi Chiou, Philip J. Atherton,
Bethan E. Phillips and Mathew Piasecki
Alimentary
1851 Diarrhoeal pathogenesis in Salmonella infection may result
from an imbalance in intestinal epithelial differentiation
through reduced Notch signalling
Andrew Quach, Rashini R. Jayaratne, Beom Jae Lee,
Stella-Rita Ibeawuchi, Eileen Lim, Soumita Das
and Kim E. Barrett
Cardiovascular
1867 Capillary module haemodynamics and mechanisms
of blood flow regulation in skeletal muscle capillary
networks: Experimental and computational analysis
Asher A. Mendelson, Edward Ho, Shayla Scott, Raashi Vijay,
Timothy Hunter, Stephanie Milkovich, Christopher G. Ellis
and Daniel Goldman
Editor’s Choice
MIX
Board from
responsible sources
FSC C020438
®
The Journal of Physiology
1889 Sexual dimorphism: increased sterol excretion leads
to hypocholesterolaemia in female hyperbilirubinaemic
Gunn rats
Josif Vidimce, Johara Pillay, Onne Ronda, Ai-Ching Boon,
Evan Pennell, Kevin J. Ashton, Theo H. vanDijk,
Karl-Heinz Wagner, Henkjan J. Verkade
and Andrew C. Bulmer Volume 600 / Number 8 / 15 April 2022
Computational physiology and modelling
1913 Multiscale model of the physiological control of myocardial
perfusion to delineate putative metabolic feedback
mechanisms
Hamidreza Gharahi, C. Alberto Figueroa, Johnathan D. Tune
15 April 2022
and Daniel A. Beard
1933 Modelling normal and nephrotic axial uptake of albumin
and other filtered proteins along the proximal tubule
Aurélie Edwards, Kimberly R. Long, Catherine J. Baty,
Katherine E. Shipman and Ora A. Weisz
(see Translational perspective)
Muscle
1953 The C2 domains of dysferlin: roles in membrane
localization, Ca2+ signalling and sarcolemmal repair
Joaquin Muriel, Valeriy Lukyanenko, Tom Kwiatkowski,
Sayak Bhattacharya, Daniel Garman, Noah Weisleder
and Robert J. Bloch
Volume 600
1969 Preserved stem cell content and innervation profile
of elderly human skeletal muscle with lifelong recreational
exercise
Casper Soendenbroe, Christopher L. Dahl,
Christopher Meulengracht, Michal Tamáš,
Rene B. Svensson, Peter Schjerling, Michael Kjaer,
Jesper L. Andersen and Abigail L. Mackey
(see Perspectives)
Number 8
Neuroscience
1991 Phase-specific pooling of sparse assembly activity
by respiration-related brain oscillations
Shani Folschweiller and Jonas-Frederic Sauer
Correction
1809–2014
2013 Erratum
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 The Journal of Physiology
Editorial
1811 Elevating physiology: Griffith Pugh on the limits
of human performance and survival
Mike Stembridge, Philip N. Ainslie and John B. West
Perspective
1815 Therapeutic effects of recreational exercise on skeletal
muscle ageing – how much is enough?
Davis A. Englund (see Soendenbroe et al. p 1969)
Translational perspective
1817 Assessing proteinuria: value added
from a mathematical model
Alan M. Weinstein (see Edwards et al. p 1933)
Journal club
1819 Sweet release – intravenous, not oral, glucose
administration increases microvascular blood flow
Jeremy N. Cohen and Jennifer A. Wilkinson
1821 Could angiotensin-II induced T-cell senescence
exacerbate age-related vascular dysfunction?
Ravinandan Venkatasubramanian,
Sophia A. Mahoney and Zachary S. Clayton
Topical reviews
1825 Hepatic stellate cells in physiology and pathology
Dakota R. Kamm and Kyle S. McCommis
1839 Ageing and exercise-induced motor unit remodelling
Eleanor J. Jones, Shin-Yi Chiou, Philip J. Atherton,
Bethan E. Phillips and Mathew Piasecki
Alimentary
1851 Diarrhoeal pathogenesis in Salmonella infection may
result from an imbalance in intestinal epithelial
differentiation through reduced Notch signalling
Andrew Quach, Rashini R. Jayaratne, Beom Jae Lee,
Stella-Rita Ibeawuchi, Eileen Lim, Soumita Das
and Kim E. Barrett
Cardiovascular
1867 Capillary module haemodynamics and mechanisms
of blood flow regulation in skeletal muscle capillary
networks: Experimental and computational analysis
Asher A. Mendelson, Edward Ho, Shayla Scott,
Raashi Vijay, Timothy Hunter, Stephanie Milkovich,
Christopher G. Ellis and Daniel Goldman
Editor’s Choice
View publication stats
Volume 600 Number 8
15 April 2022
1889 Sexual dimorphism: increased sterol excretion leads
to hypocholesterolaemia in female
hyperbilirubinaemic Gunn rats
Josif Vidimce, Johara Pillay, Onne Ronda,
Ai-Ching Boon, Evan Pennell, Kevin J. Ashton,
Theo H. van Dijk, Karl-Heinz Wagner,
Henkjan J. Verkade and Andrew C. Bulmer
Computational physiology and modelling
1913 Multiscale model of the physiological control
of myocardial perfusion to delineate putative
metabolic feedback mechanisms
Hamidreza Gharahi, C. Alberto Figueroa,
Johnathan D. Tune and Daniel A. Beard
1933 Modelling normal and nephrotic axial uptake
of albumin and other filtered proteins along
the proximal tubule
Aurélie Edwards, Kimberly R. Long, Catherine J. Baty,
Katherine E. Shipman and Ora A. Weisz
(see Translational perspective)
Muscle
1953 The C2 domains of dysferlin: roles in membrane
localization, Ca2+ signalling and sarcolemmal repair
Joaquin Muriel, Valeriy Lukyanenko,
Tom Kwiatkowski, Sayak Bhattacharya,
Daniel Garman, Noah Weisleder and Robert J. Bloch
1969 Preserved stem cell content and innervation profile
of elderly human skeletal muscle with lifelong
recreational exercise
Casper Soendenbroe, Christopher L. Dahl,
Christopher Meulengracht, Michal Tamáš,
Rene B. Svensson, Peter Schjerling, Michael Kjaer,
Jesper L. Andersen and Abigail L. Mackey
(see Perspective)
Neuroscience
1991 Phase-specific pooling of sparse assembly activity
by respiration-related brain oscillations
Shani Folschweiller and Jonas-Frederic Sauer
Correction
2013 Erratum