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DIETHYLENEGLYCOLDIMETHYLETHER Page 1
SECTION 1. IDENTIFICATION
GHS classification in accordance with the OSHA Hazard Communication Standard (29 CFR
1910.1200)
Flammable liquids : Category 3
Precautionary statements :
Prevention:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read
and understood.
P210 Keep away from heat/ sparks/ open flames/ hot surfaces.
No smoking.
SAFETY DATA SHEET
DIETHYLENEGLYCOLDIMETHYLETHER Page 2
Other hazards
No additional hazards are known except those derived from the labelling.
CAS-No. : 111-96-6
Components
Chemical name CAS-No. Concentration (% w/w)
Diethylene glycol dimethyl ether 111-96-6 >= 90 - <= 100
Actual concentration is withheld as a trade secret
DIETHYLENEGLYCOLDIMETHYLETHER Page 3
In case of skin contact : Wash thoroughly with soap and water for 15 minutes. If skin
irritation occurs, seek medical attention.
In case of eye contact : Rinse immediately with plenty of water, also under the eyelids,
for at least 15 minutes.
Get medical attention immediately if irritation develops and
persists.
Most important symptoms : The possible symptoms known are those derived from the
and effects, both acute and labelling (see section 2).
delayed No additional symptoms are known.
Specific hazards during : In case of fires, hazardous combustion gases are formed:
firefighting Carbon monoxide (CO)
Further information : In the event of a fire, wear full protective clothing and NIOSH-
approved self-contained breathing apparatus with full
facepiece operated in the pressure demand or other positive
pressure mode. Use any means suitable for extinguishing
surrounding fire. Water spray may be used to keep fire
exposed containers cool.
DIETHYLENEGLYCOLDIMETHYLETHER Page 4
Methods and materials for : Soak up with inert absorbent material (e.g. sand, silica gel,
containment and cleaning up acid binder, universal binder, sawdust).
Advice on safe handling : Store in original containers. Keep container tightly closed
when not in use. Avoid contact with air or moisture. Keep
away from heat, sparks, flames, and other ignition sources.
Store in a cool, dry, well ventilated area separate from
oxidizers and acids. Use non-sparking tools. Always bond
and ground containers before transferring the product.
Observe all necessary precautions for handling flammable
liquids.
DIETHYLENEGLYCOLDIMETHYLETHER Page 5
Hand protection
Remarks : Butyl Rubber, PVC Or Neoprene.
Skin and body protection : Wear protective clothing, including long sleeves and gloves,
to prevent skin contact.
Hygiene measures : Avoid inhalation, ingestion and contact with skin and eyes.
Remove/ Take off immediately all contaminated clothing.
After worktime and during work intervals the affected skin
areas must be thoroughly cleaned.
Appearance : Liquid
Colour : colourless
Odour : mild
pH : neutral
DIETHYLENEGLYCOLDIMETHYLETHER Page 6
60 Pa (68 °F / 20 °C)
Method: OECD Test Guideline 104
Solubility(ies)
Water solubility : miscible (68 °F / 20 °C)
DIETHYLENEGLYCOLDIMETHYLETHER Page 7
Viscosity
Viscosity, dynamic : 1,089 mPa.s (68 °F / 20 °C)
Surface tension : 69.8 mN/m, 1,000 mg/l, 68 °F / 20 °C, OECD Test Guideline
115
DIETHYLENEGLYCOLDIMETHYLETHER Page 8
Acute toxicity
Product:
Acute oral toxicity : LD50 (Rat): 4,760 mg/kg
Method: OECD Test Guideline 401
Components:
Diethylene glycol dimethyl ether:
Acute oral toxicity : LD50 (Rat, female): 4,760 mg/kg
Method: OECD Test Guideline 401
Skin corrosion/irritation
Product:
Species: Rabbit
Assessment: non-irritant
Method: OECD Test Guideline 404
Result: No skin irritation
Components:
Diethylene glycol dimethyl ether:
Species: Rabbit
Method: Other
Result: No skin irritation
DIETHYLENEGLYCOLDIMETHYLETHER Page 9
Components:
Diethylene glycol dimethyl ether:
Species: Rabbit
Result: No eye irritation
Method: Other
Components:
Diethylene glycol dimethyl ether:
Species: Mouse
Method: OECD Test Guideline 429
Result: Not a skin sensitizer.
Remarks: By analogy with a product of similar composition
DIETHYLENEGLYCOLDIMETHYLETHER Page 10
Components:
Diethylene glycol dimethyl ether:
Genotoxicity in vitro : Test Type: Ames test
Test system: Salmonella typhimurium
Concentration: 0,005-50 μl/plate
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Germ cell mutagenicity - : In vitro tests did not show mutagenic effects, In vivo tests did
Assessment not show mutagenic effects
Carcinogenicity
Product:
Carcinogenicity - : Not applicable
Assessment
Components:
Diethylene glycol dimethyl ether:
Carcinogenicity - : No information available.
Assessment
Reproductive toxicity
Product:
Reproductive toxicity - : Indications of toxic effects are available from reproduction
SAFETY DATA SHEET
DIETHYLENEGLYCOLDIMETHYLETHER Page 11
Reproductively Active
Components:
Diethylene glycol dimethyl ether:
Effects on fertility : Species: Rat, male
Application Route: Oral
General Toxicity - Parent: NOAEL: 175.1 mg/kg body weight
Method: Other
DIETHYLENEGLYCOLDIMETHYLETHER Page 12
Components:
Diethylene glycol dimethyl ether:
Species: Rat, male and female
NOAEL: 200 mg/kg bw/day
Application Route: Oral
Exposure time: 2 weeks
Method: Other
Target Organs: Testes
Remarks: By analogy with a product of similar composition
Aspiration toxicity
Product:
no data available
Components:
Diethylene glycol dimethyl ether:
no data available
Further information
Product:
Remarks: May cause birth defects.
Ecotoxicity
Product:
Toxicity to fish : LC50 (Danio rerio (zebra fish)): > 5,000 mg/l
SAFETY DATA SHEET
DIETHYLENEGLYCOLDIMETHYLETHER Page 13
Exposure time: 96 h
Method: OECD Test Guideline 203
Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 943 mg/l
aquatic invertebrates Method: OECD Test Guideline 202
Toxicity to daphnia and other : NOEC (Daphnia magna (Water flea)): 320 mg/l
aquatic invertebrates End point: Reproduction rate
(Chronic toxicity) Exposure time: 21 d
Method: OECD Test Guideline 211
GLP: yes
Components:
Diethylene glycol dimethyl ether:
Toxicity to fish : LC50 (Danio rerio (zebra fish)): > 5,000 mg/l
Exposure time: 96 h
Test Type: static test
Method: OECD Test Guideline 203
Remarks: By analogy with a product of similar composition
Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 943 mg/l
aquatic invertebrates Exposure time: 48 h
Test Type: semi-static test
Method: OECD Test Guideline 202
Toxicity to daphnia and other : NOEC (Daphnia magna (Water flea)): 320 mg/l
aquatic invertebrates End point: Reproduction rate
SAFETY DATA SHEET
DIETHYLENEGLYCOLDIMETHYLETHER Page 14
Components:
Diethylene glycol dimethyl ether:
Biodegradability : Zahn-Wellens Test
Inoculum: activated sludge, non-adapted
DOC decrease
Result: Inherently biodegradable.
Biodegradation: 99 %
Exposure time: 36 d
Method: OECD Test Guideline 302B
Bioaccumulative potential
Product:
Bioaccumulation : Remarks: Low potential for bioaccumulation (log Pow < 3).
Components:
Diethylene glycol dimethyl ether:
Bioaccumulation : Remarks: Due to the distribution coefficient n-octanol/water,
accumulation in organisms is not expected.
Mobility in soil
Product:
Distribution among : Remarks: Not expected to adsorb on soil.
environmental compartments
SAFETY DATA SHEET
DIETHYLENEGLYCOLDIMETHYLETHER Page 15
Components:
Diethylene glycol dimethyl ether:
Distribution among : Koc: 2.8
environmental compartments Method: calculated
Components:
Diethylene glycol dimethyl ether:
Results of PBT and vPvB : The substance is not identified as a PBT or as a vPvB
assessment substance.
Disposal methods
RCRA - Resource : Yes -- If it becomes a waste as sold.
Conservation and Recovery
Authorization Act
Waste Code : D001
DOT Regulation:
UN/NA-number: UN 3271
Proper shipping name: Ethers, n.o.s.
DIETHYLENEGLYCOLDIMETHYLETHER Page 16
Primary risk: 3
Packing group: III
Remarks: Shipment permitted
IMDG
UN no.: UN 3271
Proper shipping name: Ethers, n.o.s.
Hazard inducer(s): DIETHYLENE GLYCOL DIMETHYL ETHER
Primary risk: 3
Packing group: III
EmS: F-E S-D
DIETHYLENEGLYCOLDIMETHYLETHER Page 17
Further information
NFPA 704:
Flammability
2
Health Instability
0 0
Special hazard
AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Testing of
Materials; bw - Body weight; CERCLA - Comprehensive Environmental Response,
Compensation, and Liability Act; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN -
Standard of the German Institute for Standardisation; DOT - Department of Transportation; DSL -
Domestic Substances List (Canada); ECx - Concentration associated with x% response; EHS -
Extremely Hazardous Substance; ELx - Loading rate associated with x% response; EmS -
Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx -
Concentration associated with x% growth rate response; ERG - Emergency Response Guide;
GHS - Globally Harmonized System; GLP - Good Laboratory Practice; HMIS - Hazardous
Materials Identification System; IARC - International Agency for Research on Cancer; IATA -
International Air Transport Association; IBC - International Code for the Construction and
Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory
concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing
Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO -
International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO -
International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50
- Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test
population (Median Lethal Dose); MARPOL - International Convention for the Prevention of
Pollution from Ships; MSHA - Mine Safety and Health Administration; n.o.s. - Not Otherwise
SAFETY DATA SHEET
DIETHYLENEGLYCOLDIMETHYLETHER Page 18
Specified; NFPA - National Fire Protection Association; NO(A)EC - No Observed (Adverse) Effect
Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect
Loading Rate; NTP - National Toxicology Program; NZIoC - New Zealand Inventory of Chemicals;
OECD - Organization for Economic Co-operation and Development; OPPTS - Office of Chemical
Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS
- Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure
Activity Relationship; RCRA - Resource Conservation and Recovery Act; REACH - Regulation
(EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration,
Evaluation, Authorisation and Restriction of Chemicals; RQ - Reportable Quantity; SADT - Self-
Accelerating Decomposition Temperature; SARA - Superfund Amendments and Reauthorization
Act; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand
Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN - United
Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods;
vPvB - Very Persistent and Very Bioaccumulative
This information corresponds to the present state of our knowledge and is intended as a general
description of our products and their possible applications. Clariant makes no warranties, express
or implied, as to the information’s accuracy, adequacy, sufficiency or freedom from defect and
assumes no liability in connection with any use of this information. Any user of this product is
responsible for determining the suitability of Clariant's products for its particular application. NO
EXPRESS OR IMPLIED WARRANTY IS MADE OF THE MERCHANTABILITY, SUITABILITY,
FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE OF ANY PRODUCT OR
SERVICE. Nothing included in this information waives any of Clariant’s General Terms and
Conditions of Sale, which control unless it agrees otherwise in writing. Any existing
intellectual/industrial property rights must be observed. Due to possible changes in our products
and applicable national and international regulations and laws, the status of our products could
change. Material Safety Data Sheets providing safety precautions, that should be observed when
handling or storing Clariant products, are available upon request and are provided in compliance
with applicable law. You should obtain and review the applicable Material Safety Data Sheet
information before handling any of these products. For additional information, please contact
Clariant.
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