DRUG STUDY

NAME OF DRUG CLASSIFICATION INDICATION CONTRAINDICATIO ADVERSE EFFECT NURSING MONITORING

AND ACTION N RESPONSIBILITIES PARAMETERS
GENERIC NAME: CLASSIFICATION: PO, IV: Treatment of Contraindicated in CNS: seizures, >Assess patient for >
Metronidazole Therapeutic: anti- the following Hypersensitivity; dizziness, headache. infection at beginning Obtain for specimens
infectives, anaerobic infections: Hypersensistivity to EENT: tearing(topical od and throughout or culture and
BRAND NAME: Flagyl antiprotozoals, Intra-abdominal parabens(topical only); only) therapy. sensitivity.
antiulcer agents infections(maybe used first trimester of GI: abdominal pain, >Monitor neurologic >Monitor input and
PATIENT’S DOSE: with a cephalosporin), pregnancy. anorexia, nausea, status during and after output and daily
500mg MECHANISM OF Gynecologic diarrhea, dry mouth, IV infusions. Inform weight, especially on
ACTION: infections, Skin and Use cautiously in furry tounge, glossitis, physician if patients on sodium
FREQUENCY: q8 hours Disrupts DNA and skin structure history of blood unpleasant taste, numbness , restriction. Each 500
to run for 30 minutes protein synthesis in infections, Lower dyscrasias; history of vomiting parethesia, weakness, mg of Flagyl IV for
susceptible organisms. respiratory tract seizures or neurologic Der: rashes, uticaria, ataxia or seizures dilution contain 5mEq
ROUTE: IV Therapeutic Effects: infections, Bone and problems; severe burning mild dryness, occur of sodium ; each 500
infusion(ANST) Bactericidal, joint infections, hepatic skin irritation, mg of Flagyl TRU
trichomonacidal, or Septicemia, impairment(dose transient redness contains 14mEq of
amebicidal action. Endocarditis. reduction suggested); HEMAT: leukopenia sodium.
Spectrum: Most IV: Perioperative pregnancy; lactation; Local: Phlebitis at IV
notable for activity prophylactic agent in patients receiving site
against anaerobic colorectal surgery. corticosteroids or Neuro: Peripheral
bacteria, including: predisposed to edema. neuropathy
Bacteriodes, Misc: superinfection,
Clostridium. In disulfiram-type
addition, is active reaction with alcohol
against: Trichomonas
vaginalis, Entamoeba
hostolytica, Giardia
lamblia, H. pylori,
Clostridium difficile.
 DRUG STUDY

NAME OF DRUG CLASSIFICATION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING MONITORING

AND ACTION RESPONSIBILITIES PARAMETERS
GENERIC NAME: CLASSIFICATION: PO, IV: Treatment of Contraindicated in CNS: seizures, >Assess patient for >
Fluoroquinolones - Therapeutic: anti- the following bacterial Hypersensitivity. Gross dizziness, headache, infection at beginning Obtain for specimens
Levfloxacin infectives infections: UTI sensitivity among insomnia, acute od and throughout or culture and
Pharmacologic: including cystitis and agents within class psychoses, agitation, therapy. sensitivity.
BRAND NAME: Levox Fluoroquinolones prostatis, gonorrhea, may occur. confusion, drowsiness. >Observe signs and > Lab considerations:
gynecologic infections, Use cautiously in EENT: tearing(topical symptoms of May cause increase of
PATIENT’S DOSE: MECHANISM OF respiratory tract known suspected CNS only) anaphylaxis. AST, ALT, LDH,
500mg ACTION: infection including disorder, renal GI: Discontinue drug and bilirubin and alkaline
Inhibit bacterial DNA acute sinusitis, acute impairment, cirrhosis, pseudomembranous notify physician. phosphatase.
FREQUENCY: q24 synthesis by inhibiting exacerbations of geriatric patients. colitis, diarrhea, >May also cause
hours DNA gyrase. chronic bronchitis and nausea, abdominal increase or decrease
Therapeutic Effects: pneumonia, akin and pain, increased liver serum glucose.
ROUTE: IV Death of susceptible skin infections, bone function test, vomiting >Monitor
infusion(ANST) bacteria. and joint infections, VU: Vaginitis prothrombin time
Spectrum: Broad infectious diarrhea, Der: Photosensitivity, closely in patients
activity includes many intra-abdominal rash receiving
gram-positive infections. Febrile Endo: hyperglycemia, fluoroquinolones and
pathogens: neutropenia. Post- hypoglycemia warfarin; may
Staphylococci exposure treatment of Local: phlebitis at IV enhance the
including methicillin- inhalation anthrax. site anticoagulant effects
resistant MS: tendinitis, tendon of warfarin.
Staphylococcus rupture
aureus, Misc: hypersensitivity
Staphylococcus reactions including
epidermi, S. anaphylaxis, stevens-
saprophyticus, johnson’s syndrome
Streptococcus
pneumoniae, S.
pyogenes, and Bacillus
anthracis. Gram-
negative spectrum
notable for activity
against: Escherichia
coli, Klebsiella,
Enterobacter,
Salmonella, Shigella,
Proteus,
Providencia,
Morganella morganii,
Pseudomonas
aeruginosa, Serratia,
Haemophilus,
Acinetobacter,
Neisseria
gonorrhoeae,
Moraxella catarrhalis,
Campylobacter.
Additional spectrum
includes: Chlamydia
pneumoniae,
Legionella
pneumoniae, and
Mycoplasma
pneumoniae.