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Literature Review - Isabella Howell
Literature Review - Isabella Howell
Isabella Howell
Prof. Hughes
English 1201
20 March 2022
Why has the prevalence of food allergies increased over time? Having multiple food
allergies myself, this is a question I have been asking myself for as long as I can remember. In
the last few decades, the percentage of children and adults who have an allergy to food has been
exponentially increasing. Food allergies used to be rather uncommon or unheard of, but now
almost everyone knows someone with a food allergy, at least in the United States. Throughout
history, people experienced symptoms of food allergies, however, they had no idea why they
happen or who they are more likely to affect. This review presents recent studies that explore
Food allergies are a mystery for many people, especially those who have never dealt with
them. For hundreds of years people have experienced allergies, but did not know what caused the
reactions or why they occurred. Even in ancient times, it was known that food could kill people.
For example, the Roman philosopher Lucretius noted in the first century A.D. that “what is food
to one man is bitter poison to others” (National Geographic). The article, “A brief history of
allergies” by Jon Heggie describes allergies through history and how our knowledge has
advanced exponentially in the past seventy years. Heggie argues that people have always known
about allergies, but not in the way we understand today. Scientists did not know what truly
caused allergic reactions until 1967. They discovered that the many possible symptoms we
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associate with these reactions are caused by the antibody, Immunoglobulin E (IgE), when it is
All relevant sources found for this paper agreed on a few key factors concerning the
increase in food allergies over time. These factors include: the environment, a Westernized
lifestyle (developed countries vs developing countries), and the age at which the allergen is
introduced. While all studies discuss various possible factors, each tends to focus on a specific
The environment one lives in can have a lot to do with their health and whether they will
develop food allergies in infancy. An article by Benedé et al. in E Bio Medicine, states,
“Epidemiologic factors protective against food allergy include having older siblings and pet
exposure in early life...” The Benedé study also includes a glossary of scientific terms that help
the reader understand much of the medical terminology. Much research has been done,
specifically about environmental factors and how microbial bacteria seem to have a substantial
impact on children developing food allergies. In a BBC news article, Dr. Alexandra Santos, a
professor at Kings College, discusses that microbes and the environment are substantial
possibilities in food allergy formation. Santos states, “Factors may include pollution, dietary
changes and less exposure to microbes, which change how our immune systems respond”
(BBC).
Many of the sources also agree that there is a definite difference in food allergies rates
between developing countries and developed countries. There is evidence that the cleanliness of
a society affects the rate of food allergies. Dr. Santos writes about the rate of allergies, “...
improved hygiene is to blame, as children are not getting as many infections.” Santos has similar
views to the other articles about the theories behind the increase in food allergies. Santos bases
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many of the presented facts, including statistics on the number of children in the UK with food
allergies, on the EAT (Enquiring About Tolerance) study and the LEAP (Learning Early About
Peanut Allergy) study. Both studies were conducted by Kings College in the UK. According to
the research, countries that are considered “developing” have lower rates of food allergies due to
the lack of hygiene and a Westernized lifestyle. Graham Devereux, writing in Nature Reviews
Immunology, agrees with this claim and discusses that the population is becoming more
susceptible to food allergies, not because of a more toxic environment but as a consequence of
For many years people thought that introducing potential allergens to babies should not
be done until they were at least a year old. New research shows that introducing specific
allergens as early as four months old can be preventative in the infant having a food allergy. As
Benedé writes, “Introduction of peanut in the diet of infants at high risk for peanut allergy
(beginning at ages 4–11 months) was associated with a dramatically reduced frequency of peanut
allergy compared to avoidance”. Benedé goes one to talk about the studies conducted to prove the
theory that early introduction of allergens can lessen the chance the child becomes allergic to
specific food(s). Referencing the same LEAP study as Santos, Benedé manages to show the
credibility of the study and how it is revolutionary in finding the cause of the increase in food
allergies.
According to much of the research by the various sources, the environment, when the
allergen is introduced, and even where someone lives can all be factors in who develops food
allergies. While there are many theories as to why food allergies exist and are on the rise
scientists are not entirely sure of the true cause. What they do know is that the antibody,
immunoglobulin E, causes the reaction in people with an allergy. Learning about the theories as
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to why the prevalence of food allergies is on the rise has helped me to understand and become
more knowledgeable about the cause of food allergies and the theories behind the increase. The
theory about how hygiene affects the likelihood of developing an allergy is something interesting
Misconceptions about food allergies are common, even though millions of Americans
have food allergies. The severity of food allergies is usually what is the most misunderstood
because although people can die from these allergies, the general public is not particularly aware
of this. A large misconception about food allergies is that there is a cure or that they are not real,
so therefore there is not an increase. The website FARE (Food Allergy Research and Education)
has a page on the myths and misconceptions people have about food allergies, the ones discussed
above and many more. For example, food allergies are not serious or that someone can have just
a little and be fine, when in fact neither is true. Food allergies are indeed serious and even fatal.
FARE has done a great deal of research concerning food allergies and they conduct many studies
on why allergies are becoming more common. The rise of food allergies is alarming and
knowing more about them could help to lessen the chance of infants having a food allergy.
Much research has gone into what causes food allergies and why they develop, but there
is not necessarily one correct theory or answer. As of right now the only answers we have are
theories about food allergies. In biology, most of what scientists know is all theories, which is
why the rise and prevalence of food allergies does not have one clear answer. However,
exploring more about why these theories have come about would be an excellent way to further
research possible answers and find the most likely explanation for the rapidly increasing number
Works Cited
Benedé, Sara, et al. “The Rise of Food Allergy: Environmental Factors and Emerging
Devereux, Graham. “The Increase in the Prevalence of Asthma and Allergy: Food for Thought.”
Nature Reviews Immunology, vol. 6, no. 11, Nov. 2006, pp. 869–74. EBSCOhost,
https://doi.org/10.1038/nri1958.
“Food Allergy Myths and Misconceptions.” Food Allergy Research & Education,
https://www.foodallergy.org/resources/food-allergy-myths-and-
misconceptions#:~:text=Fact%3A%20Food%20allergy%20reactions%20are
%20unpredictable.&text=Myth%3A%20Food%20allergies%20aren't,breathing%20and
Heggie, Jon. “A Brief History of Allergies.” Science, National Geographic, 3 May 2021,
https://www.nationalgeographic.com/science/article/partner-content-brief-history-of-
“Increasing Rates of Allergies and Asthma.” American Academy of Allergy Asthma &
Santos, Dr Alexandra. “Why the World Is Becoming More Allergic to Food.” BBC News, BBC,