Human Reproduction Update

Systematic Review Proposal

Title1:
Running title:
Key words:

Full author list:

Corresponding author:
Corresponding author ORCID iD2:
Corresponding author e-mail:

Is the proposed review already written?

Proposed submission due date:
Is the review prospectively registered3?
Review registration number (if applicable):

Table of contents
Please include all heading levels (including 3rd & 4th level headings)

Abstract for systematic review (with or without meta-analysis)

Please complete each section under the below headings.

Introduction:
Provide a brief background of the focal topic

Objective
Define the research question(s)/primary outcome to be assessed

Rationale
Substantiate the need for the proposed review. In particular, how will the proposed
review update the field beyond recent publications?

Search methods
Define search terms, time period searched & databases interrogated; list
exclusion/inclusion criteria; detail assessment of manuscript quality and analysis of
bias

Outcomes3
List number of articles identified in search(es); as an addendum, provide a full
reference list of all studies included in (each) analyses(is)4; briefly summarise primary
outcome(s), including quality of evidence and risk of bias

Wider implications5
Summarise how the update impacts clinical practice and/or what significance it has
for reproductive clinicians and scientists.
4
Addendum of included studies

PRISMA guidelines should be followed for titles of systematic reviews (with or

1

without meta-analysis).
 Human Reproduction Update
Systematic Review Proposal
2
The corresponding author must have a validated ORCID iD. An ORCID iD can be
created at https://orcid.org/.
3
Human Reproduction Update recommends that all systematic reviews are registered
with PROSPERO (http://www.crd.york.ac.uk/PROSPERO/) or other review protocol
registries.
4
A full list of included studies is a requirement.
5
Provide a summary of the anticipated findings and impact to the field if proposed
review is not yet written