BIOCHEMISTRY II 3RD STAGE

LECTURE 7
AMINO ACIDS METABOLISM

Dr. omar Dawood salman

College of pharmacy
Amino Acid Metabolic Pathways
• Amino acid deficiency states can result if
nutritionally essential amino acids are absent from
the diet, or are present in inadequate amounts.
• Examples in certain regions of West Africa include
kwashiorkor, which results when a child is weaned
onto a starchy diet poor in protein, and marasmus,
in which both caloric intake and specific amino
acids are deficient.
• Ehlers-Danlos syndrome, a group of connective
tissue disorders that result in mobile joints and
skin abnormalities due to defects in the genes that
encode enzymes, including procollagen-lysine 5-
hydroxylase.
Mitochondria

Cytosol
urea
y
amino acids convertible to pyruvate
Serine metabolism
Cysteine
Threonine
Threonine
Glutamine & Glutamate
Amin acids Metabolism

 Proline
Histidine
Arginine
Methionine