LEGENDS: MECHANISM RISK FACTORS SIGNS AND COMPLICATIONS DISEASE MANAGEMENT

SYMPTOMS

NON-MODIFIABLE: MODIFIABLE:
▪ Age: 40 y/o and above ▪ Cholelithiasis
▪ Gender: Female ➢ Obesity
▪ Family History of Gallstones (Cholelithiasis) ➢ Rapid weight loss
➢ Oral contraceptives containing estrogen
▪ High-fat consumption
▪ Tumor

Obstruction of the cystic duct Abdominal pain (RUQ)

Nausea and Vomiting

Bile Stasis
Vitamin Deficiency

Bacterial growth Secretion and accumulation

of mucus and inflammatory
enzymes
Invades gallbladder wall then
through the wall
↑ pressure in the gallbladder Inflammation

Peritonitis
Blood vessel compression + Murphy’s sign

↑ WBC Fever
Ischemia

Cell death

Weak gallbladder wall

 Rupture of gallbladder

Bacteria in blood Sepsis

ACUTE CHOLECYSTITIS

CHOLECYSTECTOMY