BT 301 Biophysics

Tutorial Sheet-I

1. Calculate the vibration modes of the following molecules?

a. I2
b. H2O
c. CO2
d. NH3
e. CH3OH
2. What are van der Waals interactions?
3. I want you to prepare one litre of a 1M buffer (any buffer) of pH 9. How will you
go about it?
4. What is the pH of a 10-10 M solution of HCl?
5. What will be the pH of 10 M HCl solution? Can pH be negative?
6. What is activity coefficient?
7. The pKa of acetic acid is 4.75. What will be the pH of an aqueous solution of acetic
acid?
a. Is the information sufficient to determine the pH?
b. If yes, calculate.
c. If not, what else do you need?
8. What is the buffer capacity?
9. Shown below are four different Newman projections along the peptide
backbones. Identify the dihedral angle represented and tell the approximate
value.