DNA Sequencing: Maxam-Gilbert

● Radioactive tagging
● Cleavage into fragments
● Gel electrophoresis

[By w:User:Several Times (File:Maxam gilbert sequencing.png) Shakiestone (vectorization) Incnis Mrsi (tweaks) [CC BY-SA
3.0 (http://creativecommons.org/licenses/by-sa/3.0) or GFDL (http://www.gnu.org/copyleft/fdl.html)], via Wikimedia Commons]
 DNA Sequencing: Sanger

[By Estevezj (Own work) [CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons]
 DNA Sequencing: Next-generation methods

● Cheaper and
faster
● Prior knowledge
of sequence not
needed

[Grada & Weinbrecht 2013, http://dx.doi.org/10.1038/jid.2013.248]