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Plate removal following orthognathic surgery

Bart Falter, MD,a Serge Schepers, MD, DDS,a,b Luc Vrielinck, MD, DDS,a
Ivo Lambrichts, DMD, PhD,c and Constantinus Politis, MD, DDS, MHA, MM,a,c Genk, Gent,
and Diepenbeek, Belgium
ST. JOHN’S HOSPITAL, GENT UNIVERSITY, AND HASSELT UNIVERSITY

Objectives. The objectives of this study were to analyze outcomes with miniplates in orthognathic surgery and define
risk factors resulting in plate removal.
Study design. Clinical files of 570 orthognathic surgery patients operated between 2004 and 2009 were reviewed: 203
had a bimaxillary operation, 310 a lower jaw osteotomy, and 57 an upper jaw osteotomy. Age, sex, and jaw
movement were analyzed. Reasons for hardware removal were recorded.
Results. Hardware was removed in 157 patients (27.5%). Seventy-eight patients (13.7%) needed removal because of
plate-related infection; 66 (11.6%) because of clinical irritation; 5 (0.9%) for dental implant placement; and 8 (1.4%)
for other reasons. Average time between operation and removal was 9.9 months. More women (31.7%) than men
(20.3%) had plates removed, but age was not a factor except with infection.
Conclusions. More than a quarter of patients developed complications from plates and screws, necessitating their
removal, and infection occurred in 13.7%. Prompt removal constituted adequate management. (Oral Surg Oral Med
Oral Pathol Oral Radiol Endod 2011;112:737-743)

Miniplates have been widely used in the osteosynthesis MATERIAL AND METHODS
of the lower and upper jaws during orthognathic sur- Records for 570 consecutive patients operated be-
gery since Champy et al.1 adapted the technique in tween 2004 and 2009 were reviewed retrospectively
1978, as described by Michelet et al.2 In most units, it (Table II). All patients had undergone either a bimax-
is routine policy not to remove plates and screws fol- illary, a Le Fort I, or bilateral sagittal split ramus
lowing bony union unless doing so is clinically indi- osteotomies (BSSO) performed by 1 of the 3 senior
cated.3 In some units, however, the routine policy is to staff members of the Department of Oral and Maxillo-
remove plates and screws because late removal be- facial Surgery at St. John’s Hospital in Genk. Records
comes very difficult as a result of bony overgrowth of were included only of orthognathic patients for which
the plates.4 Many studies have investigated the removal the same operative technique and the same postopera-
of miniplates in trauma cases, but relatively few studies tive clinical attitude toward removal of osteosynthesis
have focused exclusively on orthognathic surgery op- material were applied.
erations. The reported incidence to date of plate re- The patients included 363 females and 207 males,
moval per patient in orthognathic surgery ranges from with a mean age at surgery of 26.7 years (Table III). A
10.0% to 18.5%5-9 in mandibular osteotomies and from total of 513 mandibular and 260 maxillary osteotomies
1.0% to 11.1%10-12 in maxillary osteotomies (Table I). were evaluated, and 203 of the patients had a bimaxil-
This retrospective study examined the rate of plate lary operation. We studied the operative charts for age,
removal from the maxilla and mandible, and the risk sex, the direction of the movement of the jaw, the
factors that may contribute to it. The purpose was to incidence of plate removal, and the type of plate that
analyze the outcome of miniplate usage in orthognathic was placed. Within the group that underwent plate
surgery and to define risk factors leading to signs or removal, we noted the indication for the removal, the
symptoms that eventually result in plate removal. interval between operation and removal, if removal was
indicated in the upper or the lower jaw, and the side
(left/right) of the jaw that needed a removal.
a
Oral and Maxillofacial Surgery, St. John’s Hospital, Genk, Belgium. This retrospective study had institutional review
b
Oral and Maxillofacial Surgery, Faculty of Medicine, Gent Univer- board approval, and was conducted in compliance with
sity, Gent, Belgium.
c
Faculty of Medicine, Hasselt University, Diepenbeek, Belgium.
the Helsinki Declaration guidelines.
Received for publication Dec 18, 2010; returned for revision Jan 3,
2011; accepted for publication Jan 8, 2011.
1079-2104/$ - see front matter
Operative technique
© 2011 Mosby, Inc. All rights reserved. All of the BSSOs included in this study were per-
doi:10.1016/j.tripleo.2011.01.011 formed by 1 of 3 resident surgeon staff members. We

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738 Falter et al. December 2011

Table I. Review of reported incidence of plate removal after bilateral sagittal split ramus osteotomy and Le Fort I
procedures
No. of % patients No. of No. of
No. of patients Orthogn/ patients w/ w/ plate plates plates % plates
First author Year receiving plates trauma Area of jaw plate removal removal inserted removed removed
Beals10 1987 53 Orthogn Maxilla — — 200 2 1.0%
Schmidt11 1998 190 Orthogn Maxilla 21 11.1% 738 70 9.5%
Manor12 1999 70 Orthogn Maxilla — 260 31 12%
Bhat5 2003 172 Trauma Mandible 28 18.3% 308 51 16.6%
Bhat6 2005 153 Trauma Mandible 21 — 308 32 —
Nagase13 2005 266 Trauma Maxilla mandible 45 33.3% 497 135 27.2%
Theodossy7 2006 80 Orthogn Mandible 16 — 160 25 15.6%
Alpha8 2006 533 Orthogn Mandible — 10.0% — 6.5%
Kuhlefelt9 2010 153 Orthogn Mandible 29 18.6% 308 56 18.2%
Falter Present data 570 Orthogn Maxilla mandible 157 27.5% 3197 622 19.5%
Orthogn, orthognathic surgery; —, data not reported.

Table II. Number of patients with plate removal ac- screws distributed by Stryker (Kalamazoo, MI, USA)
cording to the type of surgery (5.0 mm).
BSSO Le Fort All wounds were sutured with polyglactin (Vicryl) in
only Bimaxillary only Total 2 layers. During all of 2009, all sagittal split wounds
No. of patients w/ 310 203 57 570 were perioperatively rinsed with a 10% povidone-io-
an osteotomy dine (iso betadine) solution with careful closure of the
No. of patients w/ 80 63 14 157 periosteum to achieve a 3-layered closure of the oper-
plate removal
% of plate 25.8% 31.0% 24.6% 27.5%
ation wound. This change did not improve the rate of
removal plate removal and was abandoned again in 2010. No
suction drainage was used in any case of a sagittal split
BSSO, bilateral sagittal split ramus osteotomy.
osteotomy.
The Le Fort I osteotomy was performed as described
by Epker and Fish.17 All patients received perioperative
Table III. Analysis of the need for plate removal for intravenous antibiotics, as well as a dose of methyl-
different variables prednisolone 125 mg intravenously. A second dose of
Plate Non-plate methylprednisolone was administered 8 hours after the
Total removal removal % first dose. Postoperatively, antibiotic treatment was
No. of patients 570 157 413 27.5 continued for 5 days. No intermaxillary fixation was
Male 207 42 165 20.3 used, except for light elastics on surgical hooks to guide
Female 363 115 248 31.7 the patient into the right occlusion during jaw move-
Average age 26.7 26.9 26.6
ments.
The follow-up always lasted at least 18 months
and included 1 consultation every week during the
first 6 weeks and 1 at 3 months, 6 months, and 1 year
performed the modified sagittal split osteotomy as de- postoperatively. During the first 6 weeks, a wafer
scribed by Epker14 and Falter et al.15 (occlusal splint) was retained in the mouth. Guiding
After completing the osteotomies on both sides in the elastics were placed only during these 6 weeks if the
lower jaw, a wafer was introduced onto the lower jaw, occlusion deviated from the desired result. If any
and intermaxillary fixation was ensured. Internal fixa- inflammatory wound reaction was seen at the oper-
tion was established with titanium miniplates and ation site during the first 6 weeks, a removal of the
monocortical screws of the 2.0 system, as described by plates was planned at 3 months after the operation
Tulasne and Schendel16 (Fig. 1). Almost all of the date. An “infectious” reaction was considered to be
miniplates used, with the exception of 12 Tekka-plates present whenever wound dehiscence over the plates,
(Tekka, Brignais, France), were from the Leibinger granulation tissue at the plate site, or an intraoral
miniplate system (Leibinger, Tuttlingen, Germany). fistula with pus at the plate site was observed. No
The monocortical screws placed before 2008 were from wound cultures were obtained in any case. A persis-
the Leibinger system (4.0 mm); after that time, we used tent swelling and redness at the osteosynthesis site
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Volume 112, Number 6 Falter et al. 739

Fig. 1. A, Panoramic radiograph showing miniplates in place after a bimaxillary operation. Use of 2 “long 4-hole plates” per side
in the lower jaw. B, Panoramic radiograph showing 2 fractured “long 4-hole plates” on the left mandibular ramus. Two “regular
6-hole plates” were used on the right mandibular ramus.

was considered to constitute an “inflammatory” re- of the SAS System for Windows (SAS Institute Inc.,
action necessitating removal of the plates, whether it Cary, NC, USA).
was accompanied by tenderness over the area or not.
In the results section, this indication is defined as
RESULTS
“clinical irritation.” No single case of extraoral in-
A total of 157 (27.5%) of the 570 patients had at least
fection was seen. We did not encounter cold intoler-
a portion of the hardware removed because they either
ance to the plates, which Nagase and Courteman-
requested removal or required removal secondary to
che13 mentioned as an indication for plate removal.
complications related to the plates or screws. Of the
3197 plates that were placed, 622 (19.5%) were re-
Statistical methodology moved. The patients having hardware removal con-
Survival analysis techniques were used for the data sisted of 115 females (31.7% of all female patients) and
analysis. The Kaplan-Meier estimator was used to de- 42 males (20.3% of all male patients). This difference
scribe the removal rate over time and the proportional was significant (P ⫽ .0091).
hazard model (PH model or Cox model) for the analysis In 78 patients (13.7%), the plates were removed
of the effect of the covariates. The SAS procedures because of an infectious episode related to the presence
LIFETEST and PHREG were used, part of Version 9.2 of the plates (Fig. 2). Sixty-six patients (11.6%) had
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740 Falter et al. December 2011

180 166
Dental implant 160
# paents with plates remaining
140
120 # paents with plates removed
Clinical irritaon
Mandible 100
Maxilla 80 71

Infecon 55
60
42 44
32 35
40 28 24
17 18 15
0 20 40 60 80 100 20 8 12
3 0
# paents 0
<15 15-19 20-24 24-29 30-34 35-39 40-44 >44
Fig. 2. The reasons for plate removal and the number of
patients with plates removed. Fig. 3. Number of patients with plate removal according to
age group.

Table IV. Occurrence of all plate removals and occur-


rence of plate removals because of infections according
plates removed because of clinical irritation. All pa-
to patient age (3 age categories)
tients with complaints during the initial 6 weeks after
Patients Patients w/ plate
the operation had their plates removed after a healing w/ plate removal because
period of at least 10 weeks. In those cases, the removal Age No. removal, of infection, n
of the plates was bilateral, even if the occurrence of the groups, y osteotomies n (%) (%)
problems was unilateral. Eight patients (1.4%) re- ⬍25 327 87 (26.6) 36 (11.0)
quested removal for various reasons, including required 25-34 98 35 (35.7) 25 (25.5)
removal to enter the army, removal for a tooth extrac- ⬎34 145 35 (24.1) 17 (11.7)
tion, wound dehiscence, dysesthesia of the nerve, or a Total 570 157 (27.5) 78 (13.7)
malpositioning of the osteosynthesis material too close
to the inferior border of the mandible. One of the
patients had a fracture of both plates in the left mandi-
ble. In 5 patients (0.9%), the plates were removed episode (P ⫽ .0013). This finding was, rather remark-
before placement of a dental implant. Dental root inju- ably, not a linear phenomenon. It was especially the
ries, which require miniplate removal, did not occur. case in the age category of people between 25 and 35
The indications for removal also differed according years old and less so in those older than 35 and younger
to sex: 52 of the 363 females (14.3%) needed plate than 25 (Table IV). We also noted in general a slightly
removal because of an infectious episode, 55 (15.2%) higher risk for plate removal within the 25- to 35-
because of clinical irritation; 3 (0.8%) before placement year age group, but this was not a significant finding
of an implant, and 5 (1.4%) for other reasons. Among (P ⫽ .17).
male patients, 26 (12.6%) of the 207 patients had re- The average time from hardware placement to re-
moval of plates because of an infectious episode and moval was 9.9 months (range 2-65 months). Of the
only 11 (5.3%) because of clinical irritation; 2 patients removals, 79.6% occurred within the first year after the
had a removal (1.0%) before placement of an implant, operation. The average follow-up time was always at
and 3 (1.4%) for other reasons. least 18 months.
If we focus on removal because of an infectious When osteosynthesis material becomes more prom-
episode, there was no significantly higher risk for fe- inent with aging, because of soft tissue changes, this
male patients than for male patients (P ⫽ .54). Of the could be an additional reason for removal 1 or 2 de-
157 patients with plate removal, 54 had the plates cades after surgery. The follow-up period of this study
removed because a problem occurred on the left side, did not allow inclusion of these cases. The reported
41 because a problem occurred on the right side, and 62 incidence of removal is therefore an underestimation.
patients had a problem on both sides. Of the 157 patients with plate removal, 50 patients
The average age in the removal group was 26.9 years (19.2% of the 260 maxillary osteotomies) had a re-
(range 15-65 years) compared with 26.6 years (range moval of the plates from the upper jaw, and 127 (24.8%
14-65) for patients who had no removal (Table III). of the 513 mandibular osteotomies) needed removal
Generally speaking, age had no influence (P ⫽ .74) on from the lower jaw. Twenty of these patients needed a
the removal of miniplates (Fig. 3); however, it did removal in the upper and lower jaws, and were counted
significantly affect removal caused by an infectious within both groups. Also, 80 of the 157 patients
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Volume 112, Number 6 Falter et al. 741

Table V. Occurrence of plate removal according to the 40.0

number of patients and the year of the osteotomy 35.0

% miniplates removed
Patients % bimaxillary % removals 30.0
w/ plate osteotomies because of 25.0
No. removal, compared infectious 20.0
Year patients n (%) with total episode Right side
15.0
2004 45 11 (24.4) 40.0 20.0 Le side
10.0
2005 83 23 (27.7) 38.6 12.0
5.0
2006 118 27 (22.9) 28.0 12.7
2007 122 27 (22.1) 32.8 10.7 0.0
2008 103 35 (34.0) 37.9 17.5 4H R 4H M 4H L 6H R
2009 99 32 (32.3) 40.4 13.1 Type of miniplate

Fig. 4. Percentage of miniplates removed in the lower jaw


according to the type of miniplate and the side of placement.
4H R, 4 holes regular; 4H M, 4 holes medium; 4H L, 4 holes
had undergone exclusively a mandibular osteotomy large; 6H R, 6 holes regular.
(25.8%), 63 a bimaxillary surgery (31.0%), and 14
(24.6%) exclusively a Le Fort operation (Table II).
Within the group of the mandibular osteotomies, an operation, but only 7% of these had to be removed
bimaxillary operations excluded, 279 patients had a because of inflammation. They did not further specify
mandibular advancement, and 72 (25.8%) of these had the reasons for removal among the other 48%. Kramer
their plates removed. Twenty-one patients had a set- et al.20 described the removal of osteosynthesis material
back, and 6 patients had their plates removed (28.6%). in 90% of their 1000 Le Fort I osteotomies but did not
If a rotation in the movement of the lower jaw was include the indications for removal. Theodossy et al.7
done, then the risk for plate removal was 29.0% (9/31). reported a removal rate of 15.6%, but all of the plates
In examining the patient records per year, we noted had to be removed because of infection. They defined
a higher percentage of plates removed with patients infection as pain, swelling, wound dehiscence, and pus
operated in 2008 and 2009 than in the previous years of discharge in the region of the plates, which includes
2004 to 2007 (Table V). This timing coincided with a both the indications of “inflammation” and “infection”
change in the screw design of the Leibinger screws. in our series.
The incidence of plate removal resulting from an in- We prefer to use miniplates for fixation of our os-
fectious episode showed no significant changes within teotomies, which appears to be a safe and reliable
time (P ⫽ .53). procedure and excludes certain disadvantages that are
There was no correlation between the amount of seen with the use of bicortical screws, as has been
advancement and the risk of plate removal, but removal described by Borstlap et al.19 Some authors support the
rates differed according to the type of miniplate used use of 2 miniplates for 1 osteotomy site to reduce
(Fig. 4). The statistical analysis revealed no significant complications,16,21 but others do not agree.22-24 In our
difference between the use of regular or long mini- series, we used 2 miniplates for 1 osteotomy site.
plates. This study shows a high incidence of plate removal
compared with the literature (Table I). One possible
DISCUSSION reason could be that the placement of 2 plates per side
Various complications can arise after miniplate and provokes a higher risk for plate removal. The place-
screw fixation, such as infection, miniplate fracture, ment of the proximal segment screws away from the
nonunion, and mental nerve paralysis or dysesthesia.18 inferior border of the mandible could raise the risk of a
Plate removal after orthognathic surgery varies between disturbed healing.8 Our operative charts do not allow
1.0% and 18.6% of patients.7-11 Some German centers comment on this issue. Whenever a disturbed healing
advocate routine removal of titanium osteosynthesis was encountered at an osteotomy site, both plates were
material after treatment of fractures or operations for removed without notation of which screws were loose
dysgnathia.4 and which were not. The placement of 2 plates neces-
Alpha et al.8 reported plate removal in only 10% of sitates more stripping of soft tissues, both at the upper
its BSSOs, although they described “disturbance of border and at the lower border of the mandible, which
healing” in 26% of their patients. In our study, “distur- could affect the vascularization of the bone at the
bance of healing” was one of the indications to pursue osteotomy margin of the proximal segment.
surgery (42% of all removals). Borstlap et al.19 reported Another reason for the high incidence of plate re-
that 55% of plates were taken out within 8 months after moval in this study could be that the decision to remove
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742 Falter et al. December 2011

the plates was made as soon as there was a minimal plate that was used; however, analysis did not identify
margin of complaint, and we note that the relative a significant difference between using regular or long
proportion of these indications differed between the miniplates. The length of the miniplate is a good mea-
sexes. By keeping this threshold for removal rather low, sure for the dead space at the diastema of an advance-
we were anticipating in most cases that any later re- ment osteotomy of the lower jaw. The transverse ap-
moval would be more complicated because of bony proximation of the proximal and distal fragment was
overgrowth. Such overgrowth occurs in general when less with miniplates than with screw fixation of osteot-
the interval between placement and removal is longer omies. This could be an additional factor but was not
than 12 months. evaluated here.
Michelet et al.2 advocated a tight seal of the surgical There can be dead space because of a lack of bony
site with emphasis on closure of the periosteum at contacts between the proximal and distal bone frag-
fracture sites. As a meticulous closure was attempted in ments, along with a diminished vascularity of the prox-
all cases during one period (throughout 2009) without imal fragment at the osteotomy site. Under these con-
any positive effect, this factor is not an issue in orthog- ditions, overtightening of the first screw placed close to
nathic surgery. the osteotomy margin of the proximal bone fragment
Although the standard removal of all osteosynthesis could initiate compromised healing, leading to early
material is no longer promoted in the literature, contro- loss of tightening of the screw, which then could begin
versy remains about the long-term effect of titanium to act as a foreign body.
miniplates, primarily in young adults.25-28 Despite their Problems that required plate removal seemed to start
excellent clinical performance, doubts have emerged more on the left side than on the right, and it is possible
about their long-term behavior in tissues and their po- that the right-handedness of the surgeon might be a
tential local and systemic side effects.29 Because most factor. Dental root injuries resulting from miniplate
of our patients are younger than 30, we prefer to be osteosynthesis, which require a removal of the screws
cautious regarding the long-term placement of the and plates, did not occur in our series, although the
plates. Further, because the removal of plates is asso- reported incidence can be as high as 7.6% of all pa-
ciated with low comorbidity, we always choose to tients.30 These dental root traumas occur only in the
remove the plates within a minimal margin of com- upper jaw or in the distal segment of the lower jaw.
plaint, as noted. In general, we found no significant correlation be-
A third possible explanation for the high removal tween age and the risk for plate removal, in line with
rates in this study is that our patients are not placed in what has been reported by Kuhlefelt et al.9 This finding
intermaxillary fixation (IMF) postoperatively. Al- is not, however, in line with Manor et al.,12 who re-
though the double-plating method gives a strong fixa- ported that age is a statistically significant linear risk
tion that excludes the need for IMF, it is possible that factor for plate removal among patients who had un-
this practice results in micromotions at the fracture dergone orthognathic surgery. It should be noted that
site that provoke a reaction near the surgical wound. we found a significant but nonlinear correlation be-
From our results, we also note a significantly higher tween age and removal (for the 25-35 age group) in the
number of plates removed with patients operated on in specific group of cases in which infection necessitated
2008 and 2009 compared with 2004 through 2007. The the removal.
screw design could be in play here. Monocortical fix-
ation starts at the proximal segment with a first fixation
point at the upper plate close to the osteotomy site. CONCLUSIONS
Whenever we found an infection of the plates, this This study reports an important percentage of pa-
screw was always involved, having lost its fixation, tients (27.6%) developing complications from plates
with or without a loose bony fragment. It could be that and screws that required their removal. Bimaxillary
the manual tightening of this first screw was too tight, operations had higher removal rates than monomaxil-
causing microfractures close to the osteotomy site. lary operations, and women were more likely to have
There also was a relatively higher number of bimaxil- their plates removed than men. Age had no significant
lary operations in these years that accompanied a higher influence on miniplate removal, except in some cases
risk for plate removal, but this observation is not of- when an infectious episode caused the removals.
fered as a conclusive explanation but rather noted as a Almost 80% of the removed plates are removed
negative evolution. within the first year. One of the advantages of a rapid
The amount of advancement and the risk of plate removal is that all plates can be technically easily
removal showed no correlation, but we did note that removed in a procedure with low morbidity if they are
removal rates differed according to the type of mini- removed within this “window of opportunity.”
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Volume 112, Number 6 Falter et al. 743

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