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Tetanus and Rabies Infection Overview

Communicable diseases can spread from person to person. An infection occurs when a pathogenic microorganism enters the body. There are different stages of infection including incubation, prodromal, acute, convalescence, and resolution. Immunity against diseases can be natural and acquired or passive. Natural immunity is species-specific while acquired immunity develops from exposure to pathogens. Tetanus is caused by Clostridium tetani bacteria entering through wounds. It causes painful muscle spasms. Rabies virus is transmitted through animal bites and causes hydrophobia and death if the brain is infected. Dengue is transmitted by mosquitos and causes high fever, muscle pain, and bleeding disorders.

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Yuxin Liu
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0% found this document useful (0 votes)
566 views4 pages

Tetanus and Rabies Infection Overview

Communicable diseases can spread from person to person. An infection occurs when a pathogenic microorganism enters the body. There are different stages of infection including incubation, prodromal, acute, convalescence, and resolution. Immunity against diseases can be natural and acquired or passive. Natural immunity is species-specific while acquired immunity develops from exposure to pathogens. Tetanus is caused by Clostridium tetani bacteria entering through wounds. It causes painful muscle spasms. Rabies virus is transmitted through animal bites and causes hydrophobia and death if the brain is infected. Dengue is transmitted by mosquitos and causes high fever, muscle pain, and bleeding disorders.

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Yuxin Liu
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COMMUNICABLE DISEASE

Communicable Disease Contagious Disease IMMUNITY

Infection – Presence of pathogenic microorganism in the body. ➢ May resistance sa disease.

STAGES OF INFECTION 2 GENERAL TYPES

▪ INCUBATION PERIOD – entry until first s/sx. o Natural


- Species Specific
- “nandyan na ang mikrobyo”
▪ PRODROMAL PERIOD o Acquired
- Meron nang s/sx but Nonspecific. - Exposed to environment
- e.g., flu-like symptoms • ACTIVE – antibodies are produced by the
▪ ACUTE PERIOD individual himself.
- Pathognomonic sign - long term immunity
- Unique s/sx of the disease
“hallmark sign”
e.g., TETANUS → LOCK JAW,
RABIES → FEAR OF WATER,
MENINGITIS → BRUDGINSKI SIGN
→ KERNING’S SIGN • PASSIVE – antibodies are given to individual.
▪ CONVALESCENCE PERIOD
- s/sx could start to disappear -short term immunity
▪ RESOLUTION PERIOD NATURAL Passive
- Healthy
▪ Transplacental: IgG
POC (Period of Communicability) ▪ Breastfeeding: IgA

o Mild to moderate – 10 days after s/sx ARTIFICIAL Passive


o Severe – 20 days after s/sx
▪ Post exposure
-e.g., Nakatapak ng pako → tetanus.
-give within 72 hours after exposure.
ISOLATION QUARANTINE (if possible)
o Applicable to o Based on longest
patients with s/sx incubation period
o (+) Disease o Exposed to the
o Mild to moderate – disease.
10 days after s/sx
o Severe – 20 days
after s/sx

1
TETANUS RABIES
➢ Other name: LOCK JAW

CAUSATIVE AGENT: Clostridium Tetani (bacteria) →Toxigenic DIAGNOSTIC TEST:

MODE OF TRANSMISSION: Wound o Observe the dog for 14 Days.


o Brain biopsy
SYMPTOMS: -Negri bodies
o Trismus o Fluorescent
-Affected: Trigeminal Nerve Rabies
o Opisthotonos – Arching of the back Antibody Confirmatory Test
- Best Position: Side lying Test
o Risus Sardonicus

MANAGEMENT:

o Penicillin (IV)
o DOC: Metronidazole

NURSING RESPONSIBILITY

o Avoid alcohol

PREVENTION

o Avoid of wounds
o Administer Tetanus Toxoid
o First Aid
→ nasa katawan pa lang yung Virus.
RABIES
MANAGEMENT
➢ Other name: LYSSA
o First Aid: wash the wound
CA: Rhabdo Virus → bullet shape virus o TT + TiG
MOT: o Rabies immunization
▪ Active immunity
o Animal bite - Verorab/Immurab
o Scratch (rare) - IM/ID
o Tissue transplant (rare)
- 5 doses
o Airborne-Droplet
- Day: 0,3, 7, 14, 28, 90
S/SX ▪ Passive immunity
Based on the patient’s
-HRIG (Human Rabies IG)
o Invasive stage – kaka-akyat lang ng virus sa utak. body weight.
-PRODRORAM STAGE:
-ERIG
▪ Fever
▪ Photophobia
▪ Headache
▪ Numbness (site) → pag nasa utak na yung Virus
o Excitement Stage
▪ Strict isolation
▪ Hydrophobia – fear of water
▪ Nonstimulating
▪ Aerophobia
▪ Maniacal behavior – nanghahabol ng tao environment
o Paralytic Stage - Generalize Paralysis ▪ Avoid any sense of
fluid stimulant
▪ Cover IVF

2
DENGUE, MALARIA, FILARIASIS
High fever
DENGUE
o Viral test
CA: Dengue Virus
- PCR Test
▪ TYPE 1,2,3,4 - CONFIRMATORY
o CBC
Mas delikado: 2nd time - Platelet: Low
- HCT: High
MOT: Mosquito Bite (Vector) → Aedes Aegypt
o Serological Test
*Delikado during Defervescent Stage - (+) Ab

S/Sx

▪ Pain
→ Headache
→Retroviral Pain (Eye)
→ Muscle, bone, joint
▪ Herman’s sign
▪ Petechiae

WARNING SIGNS!!

▪ Abdominal Pain/tenderness
▪ Liver enlargement
▪ Persistent vomiting
▪ Mucosal bleeding
▪ Lethargy/ restlessness MANAGEMENT
▪ Decrease platelet ▪ Antipyretics
▪ Increase HCT - Paracetamol
▪ Clinical Fluid Accumulation: - Fluid Replacement
o Pleural Effusion - DENGUE FEVER → ORESOL
o Ascites - (+) WARNING SIGN → CRYSTALLOID SOLUTION
▪ Decrease platelet • LR
▪ Increase HCT
• NSS
▪ Clinical Fluid Accumulation:
- SEVERE → CRYSTALLOID SOLUTION
o Pleural Effusion
• Albumin
o Ascites
• Starch
▪ No dark color food/drink
▪ ALTERNATIVE MGT:
DX: - Tawa-tawa
o Tourniquet Test/Rumpel Lead Test → for community - Vanilla Ice cream
- (+) 1 or 2.5 cm / 20 or more petechia - Durian
- (-) <20 - Dahoon ng papaya
- CONTRAINDICATION: - Quail’s Egg
▪ Dehydration
▪ Active bleeding

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