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Abstract — In this study, we designed an unobtrusive strip-type sensors attached to them, and it is only possible to perform PSG
sleep monitoring system including a force sensor and algorithms sleep monitoring in a designated laboratory, as opposed to a
for the detection of awakening and respiration rate. The developed normal sleeping environment. In addition, the monitoring pro-
system is installed on a mattress across the user's chest in order to
cess is expensive, requires a skilled technician, and is limited to
measure the trunk movement induced by respiration or body mo-
tion. Thirty subjects’ clinical data, which contain signals that were one-time monitoring. Considering that sleep is a repetitive ac-
measured simultaneously using the developed system and a poly- tivity that occurs daily, PSG is difficult to apply to daily sleep
somnograph (PSG), are used to validate the accuracy of the devel- health management.
oped system. The awakening detection, accuracy, sensitivity, spec- There have been several attempts to simplify PSG. Wrist
ificity, and Kappa coefficient of the designed system were 79.4%, actigraphy is a representative alternative for daily sleep moni-
48.3%, 86.9%, and 0.6, respectively, and the average sleep effi-
toring [1-3]. It measures the amount of activity that occurs in
ciency was 82.3% in the developed system and 84.0% in the PSG
with root-mean-square- error of 17.7%. In terms of respiration one’s wrist during sleep and uses this to analyze the person’s
rate detection, it was shown that the respiration rate measured sleep patterns and awakening during sleep. Among the wrist-
with the developed system can trace the PSG-measured respira- type sleep monitoring devices, Actiwatch (Philips Respironics,
tion rate. The accuracy to detect respiration rates within one, two, Oregon, USA) has been approved by the US Food and Drug
and three breaths per minute error were 76.4%, 97.2%, and Administration (FDA) and is used to clinically analyze the sleep
99.4%, respectively.
patterns of insomnia patients [4]. Wearable devices can monitor
Index Terms — Awakening state detection, PVDF (polyvinyli-
dene fluoride), Respiration rate detection, Sleep monitoring, Un- sleep status more easily than PSG. Therefore, they are much
obtrusive measuremnt more suitable for sleep health management in daily life; how-
ever, they constrain a user’s body because they have to be worn
I. INTRODUCTION at all times during sleep. It is also difficult to use for continuous
monitoring because it must be actively managed by the user.
P olysomnography (PSG) is the gold standard sleep monitor-
ing method that is used clinically to diagnose sleep disor-
ders. While PSG has the advantage of being able to accu-
In recent years, studies have been conducted for both remote
and unobtrusive measurement methods to improve conven-
rately diagnose sleep disease, it also has several limitations: it tional constrained-type sleep monitoring devices. Remote
is necessary for the subject to sleep with a large number of measurement methods monitor the human body without the
need for contact. The methods typically used to remotely meas-
ure body signals include radiometry based on radar signals [5],
Submit Date :
* This research was supported by the MSIP(Ministry of Science, ICT and
microphones measuring sounds generated by bio-activity or
Future Planning), Korea, under the ITRC(Information Technology Research snoring during sleep [6, 7], thermal cameras for measuring tem-
Center) support program (IITP-2018-2014-1-00720) supervised by the perature changes of the face during sleep [8], fiber optics for
IITP(Institute for Information & communications Technology Promotion) and
by the Bio & Medical Technology Development Program of the NRF funded
measuring body movement monitoring [9], millimeter wave for
by the Korean government, MSIP (NRF-2016M3A9F1941328). heart rate and respiration rate detection [10], infrared camera
S. Park is with the Department of Biomedical Engineering, Chonnam Na- and motion sensor for sleep monitoring [11], ultrasonic piezo
tional University, 50 Daehak-ro, Yeosu, South Korea (e-mail: transducer for capturing ultrasound reflections from heart and
susie.soo718@gmail.com)
H.-H. Cho is with the Department of Otolaryngology-Head and Neck Sur- surrounding organ motions due to the breathing [12], and Dop-
gery, Chonnam National University Medical School and Chonnam National pler rader for respiration monitoring [13]. Remote methods
University Hospital, Gwangju, South Korea. (e-mail: victocho@jnu.ac.kr) have the advantage of the user being free from the measuring
H. C. Yang is with Department of Otolaryngology-Head and Neck Surgery,
Chonnam National University Medical School and Chonnam National Univer- device. However, they are limited in that the results can be eas-
sity Hospital, Gwangju, South Korea. (e-mail: dr.yang@hanmail.net) ily distorted by exceptional environmental changes, such as ra-
J.-S. Yoon is with the Department of Psychiatry, Chonnam National Univer- dio signals, ambient noise, room temperature changes, and so
sity Medical School, Gwangju, South Korea (e-mail: jsyoon@jnu.ac.kr)
H. Shin is with the Department of Biomedical Engineering, Chonnam Na- on.
tional University, 50 Daehak-ro, Yeosu, South Korea (e-mail: hang- The unobtrusive method measures physiological signals with
sik.shin@jnu.ac.kr).
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This article has been accepted for publication in a future issue of this journal, but has not been fully edited. Content may change prior to final publication. Citation information: DOI 10.1109/JSEN.2018.2883716, IEEE Sensors
Journal
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This article has been accepted for publication in a future issue of this journal, but has not been fully edited. Content may change prior to final publication. Citation information: DOI 10.1109/JSEN.2018.2883716, IEEE Sensors
Journal
TABLE II
SPECIFICATION OF THE DEVELOPED DATA ACQUISITION MODULE
Property Description Unit
Number of ADC channel 24 -
ADC bit depth 14 bit
ADC range 0-1.45 V
ADC resolution (about) 88.5
kHz/Chan-
Maximum sampling frequency 1
nel
Connectivity WiFi, Bluetooth 4.0 -
Fig. 3. Analog front-end circuit of a single channel
Fig. 6. Algorithms for awakening and respiration rate detection using movement signals.
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Fig. 8. The process of threshold decision for awakening state detection
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TABLE III
SUBJECT’S INFORMATION
Gender Age BMI Total Sleep
No. (M/F) (years) (kg/m2) Time* Diagnosis
(minutes)
1 M 38 22.9 427 IS, SN
2 M 47 25.0 484 OSA, SN
3 M 36 28.7 551 OSA
4 M 51 27.5 424 OSA, SN, PLMS
5 M 51 23.8 493 IS
6 M 22 24.5 464 SN
7 M 23 36.8 499 OSA, SN
8 M 51 24.5 467 PLMS
9 M 52 26.1 442 OSA, SN
Fig. 9. Experimental setup of an unobtrusive force measurement system
10 M 57 23.4 505 IS, SN, PLMS
11 F 56 19.5 497 IS, SN, PLMS (SpO2), chest and abdominal respiratory movement signal, res-
12 M 64 26.6 482 OSA, SN
piratory air flow, sound of snoring, and the position of the body
13 M 31 26.3 514 IS
14 M 55 26.0 505 IS
were all recorded using PSG equipment, Embla N7000 (Embla
15 F 65 27.8 413 IS, OSA
systems, Ontario, Canada) [19].
16 M 63 24.3 511 OSA, SN The developed system was installed between the mattress and
17 M 63 29.7 529 OSA, SN, PLMS the mattress cover, and attached with adhesive tape. It was laid
18 M 74 24.9 292 OSA, SN, PLMS across the subject's chest in order to measure the force changes
19 M 21 22.0 519 OSA, SN caused by the subject's motion during sleep. The signal was
20 M 21 24.7 481 Normal measured at a sampling frequency of 1 kHz. Fig. 9 shows the
21 M 23 30.0 538 OSA, SN experimental setup of the developed system.
22 M 50 24.1 496 OSA, SN
23 M 62 23.0 424 OSA, SN B. Preprocessing
24 M 49 29.4 535 OSA, SN Although the measurements using the developed system and
25 M 52 19.8 517 OSA, SN PSG were performed simultaneously, a timing difference be-
26 M 63 22.5 379 OSA, SN tween the two different measuring instruments is inevitable.
27 F 54 27.2 447 IS, OSA, SN Therefore, post-synchronization is required for accurate evalu-
28 M 54 31.2 483 OSA, SN ation. Cross correlation is used to analyze how similar signals
29 M 51 25.1 493 OSA are over time. In order to compensate for timing difference, we
30 M 24 19.0 494 Normal
find the time lag that maximizes the correlation coefficient, then
SN (N=21), OSA adjust the timing with that time lag. If time synchronization can-
Mean M 27 47.0 25.8 476.8 (N=20), IS (N=8)
(SD) F3 (16.0) (3.8) (53.6) PLMS (N=6), nor- not be achieved through the above method, the time difference
mal (N=2)
is then corrected manually.
*
Total Sleep Time is defined as a time between light-off ans light-on In analysis, only the data between the 'light off', which is the
IS: Insomnia, SN: Snoring, BMI: body mass index, OSA: Obstructive sleep
apnea syndrome, PLMS: Periotic limb movement in sleep, SD: Standard de-
start point of the analysis of PSG, and 'light on' at the end point
viation was used. In addition, the signal measured by the proposed sys-
University Hospital sleep testing laboratory and approved by tem used only the second channel data, having excellent meas-
the Institutional Review Board (IRB) of Chonnam National urement results of the two channels. Matlab R2016a (Math-
University biomedical research ethics committee. (IRB No. works, Inc., Natick, USA) was used for signal preprocessing,
CNUH-2017-274) algorithm development, and evaluation.
As an experiment, diagnostic overnight PSG was performed, C. Awakening detection
and a total of 39 subjects participated. Ultimately, data from 30
The sleep stage, which is one of the results of PSG, was di-
participants were used; nine subjects were excluded because
vided into WAKE, NREM (stage 1, stage 2, stage 3, stage 4),
their data was not properly acquired due to operational error. In
and REM based on the characteristics of EEG and EOG [19].
evaluating the respiration rate detection, only data from 26 sub-
In this study, we divided sleep state into two classes; ‘awaken-
jects were used because four subjects whose reference signals
ing’ and ’sleep’. A WAKE sleep stage was considered an
were not measured were excluded.
‘awakening’ state, while NREM and REM were considered to
The subjects included patients who had sleep disorders, such
correspond to a ‘sleep’ state.
as obstructive sleep apnea (OSA), snoring (SN), periodic limb
In order to evaluate the awakening detection algorithm, we
movement during sleep (PLMS), or insomnia (IS). All subjects
evaluated its accuracy, sensitivity, specificity, Cohen's Kappa
who participated in the experiment were provided with suffi-
coefficient, and sleep efficiency in comparison to PSG. In this
cient information regarding the purpose and method of the
evaluation, 'accuracy' refers to the probability of classifying a
study and informed consent was obtained from all subjects. Ta-
awakening state in PSG as an awakening state in the proposed
ble III shows a summary of the subjects’ information.
system, and classifying a sleep state in PSG as a sleep state in
PSG was performed according to the reference sleep test man-
the proposed system; 'sensitivity' refers to the probability of a
ual. Electrocardiogram (ECG), electrooculogram (EOG), chin
result being classified as an awakening state in the proposed
electromyogram (EMG), saturation of percutaneous oxygen
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This article has been accepted for publication in a future issue of this journal, but has not been fully edited. Content may change prior to final publication. Citation information: DOI 10.1109/JSEN.2018.2883716, IEEE Sensors
Journal
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Journal
algorithms for awakening state detection and respiration rate distinguishable with a performance similar to those of existing
detection, which are important indicators in sleep health man- motion-based sleep monitoring devices. This will overcome the
agement, have been developed. disadvantages of wearable devices that require direct wearing
The performance of the awakening state detection algorithm of the sensor during sleep, and it will enable periodic and long-
of the proposed system can be compared with the results of pre- term sleep monitoring in an easy and convenient way. However,
vious studies that have focused on actigraphy, which is a repre- in order to apply it to everyday life, optimization processes and
sentative motion-based sleep monitoring method (see Table IV). furthur validations are needed through various cases of clinical
Kushida et al. developed an actigraphy-based awakening state trials, including sleep disorders or simple testing in daily living.
detection algorithm and compared it with PSG across 100 pa- Furthermore, there is a need to expand the parameters for mon-
tients with sleep disorders [2]. Compared to the results of pre- itoring sleep health, such as sleep apnea detection and others.
vious studies, the average accuracy and average sensitivity of
the proposed system are higher, but the average specificity is ACKNOWLEDGMENT
lower. This means that the proposed system achieves perfor- We would like to thank to Ji Yhea Kim and Han Byeon of
mance comparable to that of the actigraphy, but that the mis- Clinical Trial Center, Chonnam National University Hospital,
classification rate of sleep states as awakening states is higher. Geun Ho Lee and Youyang Jin of the sleep testing laboratory,
In addition, the Kappa statistics showed that the awakening Chonnam National University Hospital for assistance in data
state detection results of the proposed system show significant collection and scoring polysomnography.
similarities with the PSG results. The reason for the low speci-
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