CHPT 12 IMMUNITY

1. When T cell recognizes antigen, T cell will

A release antibody B release interpherone C divide more
D dissociate the cell composition E move from thymus to the spleen

2. Which of the following is true about antigen?

I it is a protein or combination of protein with polysaccharide
II it is found at the wall or outer membrane of the invading organism
III it is produced by lymphocytes
IV it is produced as the reaction to the presence of non self substance
A I and II B I and IV C II and III D II and IV E III and IV

3. Which of the following events occur during the infection of HIV?

I RNA virus forms DNA
II RNA virus and an irreversible transcriptase are released
III DNA virus combines with T4 cell of DNA
IV protein virus attaches to the protein on T4 cell surface
V virus replication occurs in T4 cell
Which of the following is the correct order for the above events?
A I,II,III,IV,V B II,I,III,IV,V C II,III,I,V,IV D III,IV,V,II,I E IV, II, I, III, V

4. Which of the following is correctly matched for each type of cell and its function?
A macrophage – digests bacteria
B plasma cell-produces antibody
C Helper cell – infects the lysis cell
D memory cell- divide to produce spontaneous reaction hen infection occurs
E cytotoxic T cell – defends against the intracell pathogen by infecting the lysis cell

5. Among the following, which is/are the symptoms of AIDS in human beings?
I continuous diarrhea II decrease in body weight
III herpes simplex infection IV inflammation of lymph nodes
A I and II B I and IV C II and III D II, IV and V E I, II, III and IV

6. The diagram below shows the humor reaction scheme in the formation of immunity.
What are the components represented by I, II, III and IV in the scheme above?
I II III IV
A Plasma cell B cell Antibody Reminder cell
B Plasma cell B cell Reminder cell Antibody
C B cell Reminder cell Plasma cell Antibody
D B cell Plasma cell Reminder cell Antibody

7. Whenever T cell identifies an antigen, the T cell would

A release interference B divide excessively
C dissolve the antigen D decompose the cell content
8. The diagram below shows the immune response in the human body.
Which statement about the diagram is true?
A cell X excretes lymphokine, then divides to form
cells Y and Z in the presence of substance T
B Cell Z responds quickly towards the repeated
infection of a particular disease
C Cell Y prepares other lymphocytes to produce
antibodies
D Substance S regulates lymphocytes involved in the
immune response

9. Which of the following enables HIV to act dormantly in the human body?
A the virus rests in the cytoplasm of T$ cell B the viral DNA integrates into the DNA of T4 cell
C the viral RNA takes some time to replicate D the viral reverse transcriptase is engulfed by T4 cell

10. Which of the following statements are true about T cells?

I T cells produce antibodies
II T cells reach their maturity in the bone marrow
III cytotoxic T cells kill the cells which are infected by antigen
IV suppressor T cells suppress the action of cytotoxic T cells
A I and II B I and IV C II and III D III and IV

11. Which of the following involve in the cell mediated immune response?
I lymphokine II plasma cells III cytotoxic T cells IV helper T cells
A I and II B III and IV C I, II and III D I, III and IV

12. What do W, X, and Y represent in the following simplified flow chart of the humoral response?

W X Y
A B cell Memory B cell antibody
B B cell antibody Memory B cell
C T cell Memory T cell Helper T cell
D T cell Memory T cell Cytotoxic T cell

13. Which of the following are true of B cell?

I it forms immunity through the humoral response
II it forms immunity through the cell mediated mechanism
III it is produced and it achieves maturity in the bone marrow
IV it is produced in the bone marrow and it achieves maturity in the thymus gland
A I and II B I and III C II and IV D III and IV

14. The site on the antigen recognized and attached by the antibody is called
A an epitope B an active site
C an antigen binding site D a major histocompatibility complex
15. Based on the table below, match the types of immune response to the structures involved.

Type of immune response Structure

I specific P skin
II non-specific Q antibodies
R lymphocytes
S phagocytic white blood cells
P Q R S
A I I II II
B I II I II
C II I I II
D II I II I

16. The following are several steps in the reproductive cycle of HIV
I the formation of a provirus
II the transcription of viral DNA
III the removal of capsid proteins and the release of viral genomes
IV the formation of DNA catalyzed by reverse transcriptase enzyme
Which of the following is the correct sequence of the reproductive cycle of HIV?
A I, III,II, IV B II,IV,I,III C III,IV,I,II D IV,II,III,I

17. During the primary immune response, the main antigen-presenting cells are
A plasma cells B macrophages C B lymphocytes D T lymphocytes

18. What is injected into the body of a person bitten by a dog?

A dead bacteria B weakened viruses
C serum containing antigens D serum containing specific antibodies

20. In the process of initiating humoral-immune response in humans, the role of the helper T cell is to secrete
A perforin to lyse the infected cell
B interleukin I to stimulate B lymphocytes to differentiate into plasma and memory cells
C interleukin II to stimulate B lymphocytes to differentiate into plasma and memory cells
D interleukin II to stimulate T lymphocytes to differentiate into cytotoxic T and memory cells

21. Which leucocyte can trigger a specific immune response?

A lymphocyte B neutrophil C eosinophil D monocyte

22. Three types of cells involved in immune response and their functions are shown in the table below.

Type of cell Function

I B cell P destroys cancer cells
II Helper T cell Q differentiates into memory and plasma cells
III cytotoxic T cell R secretes cytokines that active macrophages

Which cells correspond to their functions?

I II III
A P Q R
B P R Q
C Q P R
D Q R P
23. The cells of the immune system and their functions are shown in the table below.
Cell Function
I B cell P secretes interleukin II
II Helper T cell Q triggers allergy symptoms
III macrophage R carries out humoral immunity
IV mast cell S kills microorganisms by phagocytosis

Which cells correspond to their functions?

I II III IV
A P Q S R
B R P S Q
C R S Q P
D S P R Q

24. The immune response of a human body after a second pathogen infection is shown in the graph below.
What causes a rapid and higher response upon the second exposure?
I the presence of memory B cell after the first infection
II the presence of memory T cell after the first infection
III the presence of helper T cell after the first infection
IV the presence of killer T cell after the first infection
A I and II B I and III C II and IV D III and IV

25. Helper T cell binds to macrophage through

A the epitope
B the antigen –presenting cell
C class I MHC-antigen complex
D class II MHC-antigen complex