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HLTB16
HLTB16
Lecture 1
What is Public Health?
● “The activities that ensure conditions in which people can be healthy. These activities
include community-wide efforts to identify, prevent, and combat threats to the health of
the public.” - Institute of Medicine Definition of Public Health
Defining Public Health
● “The science and art of preventing disease, prolonging life, and promoting health
through the organized efforts and informed choices of society, organizations, public and
private communities, and individuals.” -CEA Winslow
Public Health’s Mission
● “Fulfilling society’s interest in assuring conditions in which people can be healthy.”
-Institute of Medicine
● “Public health aims to provide maximum benefit for the largest number of people.” -
World Health Organization
What Public Health Means to Everybody
● Access to fresh clean water
● Puts emphasis on healthier lives
○ Adopting healthy behaviors such as doing activities like riding bikes
○ Provide opportunities so people can engage in activities
● Public health generates evidence to guide policies that can move towards reducing or
shifting population health behaviors to reduce smoking rates
● Reduce infections and such with vaccines
○ Helped save lives
What Public Health Aims to Achieve
● Safer workplaces
● Vaccination
● Motor vehicle safety
● Fluoridation of drinking water
● Control of infectious diseases
● Recognition of tobacco as a health hazard
● Family planning
● Healthier mothers and babies
● Safer and healthier foods
● The decline in deaths from heart disease and stroke
Public Health Core Sciences
● Prevention effectiveness
● Epidemiology
● Laboratory
● Informatics
● Surveillance
The 10 Essential Public Health Services
● Monitor the health status of the community
● Investigate and diagnose health problems and hazards
● Inform and educate people regarding health issues
● Mobilize partnerships to solve community problems
● Supports policies and plans to achieve health goals
● Enforce laws and regulations to protect health and safety
● Link people to needed personal health services
● Ensure a skilled, competent public health workforce
● Evaluate effectiveness, accessibility, and quality of health services
● Research and apply innovative solutions
A Public Health Approach
● Public health approach
○ Focus on the broader population
○ Disease prevention & health promotion and protection
○ Population-wide interventions
○ Influence and regulate social, economic, and health policies
● Individual approach
○ Individually-driven interventions
○ Diagnoses and treatment limited within health care settings
○ Opens avenues for privatized care, limited impact on an individuals health
Cholera
● A fatal communicable disease, which spread vastly in the 1800s in Longdon, contributing
to 1000’s of deaths in the area
● Many believed cholera was caused by bad air (miasma theory).
● The major source of contraction is contaminated water
● John Snow
○ Father of modern epidemiology
○ Traced the source of the cholera outbreak
○ A cluster of Cholera Cases, London- 1854
○ Interviewed and asked people where they were getting their water
● Interventions
○ Through continuous research, Snow was able to determine that the cause of the
disease was the contaminated water supply on a larger scale
● Implementation
○ His research convinced the British government that the source of cholera was
water contaminated with sewage and the pump on Broad street was disabled
What is Public Health’s Philosophy
● Healthy equity
● Social justice
● Social determinants of health
5 Essential Pillars of Public Health
● Social determinants of health
● Evidence-informed public health
○ Evaluate the weight of the evidence
■ Is it strong enough?
● Primary health care
● Health promotion & prevention
● Holistic care paradigm
○ The interconnectedness between the mind, body, the spirit, the culture, and the
environment
○ They come together to get a view of the world
What Determines the Health of the Population?
● Genes and biology
● Health behaviors
● Medical care
● social/societal characteristics; total ecology
Example: Your Neighborhood From a Public Health Perspective
● Neighborhood features
○ Living close to health food sources e.g. supermarkets
○ Living farther away from unhealthy food sources- e.g. convenience stores, fast
food outlets
○ Zoning of unhealthy food sources
○ Farmers’ markets
○ Community gardens
● Mediating factors
○ Examples:
■ Low prices
■ Convenient store hours
■ Long growing season
■ Food security
● Human response
○ Healthy diets
● Health outcomes
○ Reduced risk for:
■ Premature death
■ Obesity
■ Diabetes
■ Poor mental health
● Other determinants of health
○ Age
○ Genetics
○ Social environment
○ Income
○ Education
○ Culture
○ Health care system
The Bell-Curve Shift in Populations
● Shifting the whole population into a lower risk category benefits more individuals than
shifting high-risk individuals into a lower risk category
Controversies in Public Health
● Economic
○ All goods, services, industries
○ PH initiatives may reduce profits, inflate prices, increase taxes (i.e. tobacco)
● Libertarian
○ Individual freedom vs. community health
○ Promote neoliberalism, paternalism individual autonomy (i.e. market justice)
○ Public health generates evidence - does not create policies
● Moral
○ Differing moral views (i.e. abstinence vs. birth control)
○ Obesity as a cultural norm, e-cigarettes, prescription drug abuse, antibiotic
resistance, gun control, preventing concussions, climate change
The tragedy of the Commons
● The more we exploit our environments, over time it will deplete our resources, and it’s
going to impact lower ses.
Public health and the global burden of infectious disease
○ History of pandemics
○ Many pandemics that took away many lives
○ Headed in the direction such as the Spanish Flu, Hong Kong flu
Breaking News: 2020 is Canceled
● Quarantining
● Social distancing
● Working from home
● Closing schools and other institutions
● Placing hard limits on the size of crowds at events
History of Public Health
● Ancient Greeks (500-323 BC)
○ Personal hygiene and sanitation
○ Physical fitness
■ Olympics (competitive games and source of entertainment)
○ “Humorism” concept
■ Disease caused by an imbalance between the human body and the
surrounding environment
○ Largely influenced by Hippocrates
● Hippocrates (-460 BC)
○ Father of Western Medicine
○ Causal relationships
■ Disease and climate, water, lifestyle, and nutrition… and health
■ 4 humours
● Blood
● Phlegm
● Black bile
● Yellow bile
○ Coined the term epidemic
■ Epid (“on” or “akin to”)
■ Demos (“people”)
● Roman Empire (23 BC-476 AD)
○ Adopted Greek health values
○ “A healthy mind in a healthy body” - Juvenal
○ Galen = followed Hippocrates methods (deep breathing)
○ Great engineering plans
■ Sewage systems
■ Aqueducts
■ Army camps
○ Administration
■ Public baths
■ Water supply markets
● Roman Aqueducts
○ Bright in water for public baths, supplied private household, farming, mining, etc
● Middle ages (476 AD-1450 AD)
○ Shift away from Greek and Roman values
■ The physical body less important than the spiritual self
■ The decline of personal and community hygiene and sanitation
○ Beginnings of PH strategies
■ Quarantine of ships
■ Isolation of diseased individuals
○ Leprosy was the worst disease at the time
● The plague
○ 25% to 50% of the population wiped out
● Renaissance and Global Expansion
○ Over time, diseases were vastly spread by merchants, traders, and explorers
○ Resulting in killing nearly 90% of indigenous people in the New World
● Age of Enlightenment (1650- 1800 AD)
○ Giving rise to Modern Medicine (scientific revolution)
○ Separation of the church and the state
○ Rise of empiricism and rational thought
○ William Harvey
■ 1628 theories of circulation
○ Edward Jenner
■ 1796 cowpox experiment
■ Coined the term vaccine (Vacca, Latin for “cow”)
■ Injected a little boy with cowpox and then he never got it again
● Great Sanitary Awakening
○ Adoption and acceptance of scientific inquiry and knowledge
○ Humanitarian approaches to disease and illness
○ The linkage between poverty, living conditions, and disease
○ Investment in improving water and sanitation access (clean sewage, public
awareness)
○ Surveillance and monitoring of individual and community health
○ Graph
Focus Areas
● 13 provincial standards:
○ These include “foundational” standards (for monitoring population health data,
decreasing health inequities, and implementing effective public health practice
and emergency management)
○ Programmatic ones (food safety, health environments, health growth and
development, immunization, infectious and communicable diseases prevention
and control, safe water, school health, substance use and injury prevention, and
chronic disease prevention and well being)
○
● Chronic disease prevention and well being
○ To reduce the burden of chronic diseases of public health importance and
improve well being
● Food safety
○ To prevent or reduce the burden of food borne illnesses
● Healthy environments
○ To reduce exposure to health hazards and promote the development of healthy
built and natural environments that support health and mitigate existing and
emerging risks, including the impacts of a changing climate
● Healthy growth and development
○ To achieve optimal preconception, pregnancy, newborn, child, youth, parental,
and family health
● Immunization
○ To reduce or eliminate the burden of vaccine preventable diseases through
immunization
● Infectious and communicable disease prevention and control
○ To reduce the burden of communicable diseases and other infectious diseases of
public health significance
● Safe water
○ To prevent or reduce the burden of waterborne illnesses related to drinking water
and recreational water use
● School health
○ To achieve optimal health of school aged children and youth through partnership
and collaboration with school boards and schools
● Substance use and injury prevention
○ To reduce the burden of preventable injuries and substance use
Epidemiology and Surveillance
How did Taiwan handle COVID-19?
● Total cases: 503, deaths = 7
● How?
● Travel and quarantine (early)
● Clear plan and good leadership
● Ahead of mask shortages
● Regular communication
● Digital healthcare system
● Community mindedness and solidarity
● Missing
○ More education around prevention
○ Masks for foreigners
○ Privacy policy- loose?
○ Flexibility around work from home
Epidemiology
● Study of the distribution and determinants of disease frequency in human populations
● Epidemiology aims to:
○ Discover the agent, host, and environmental factors
○ Determine the relative importance of causes of illness, disability, and death
○ Identify segments of the population with greatest risk
○ Evaluate the effectiveness of health programs and services
●
Three essential characteristics of epidemiology
● Person
○ Age, gender, ethnic group
○ Genetic predisposition
○ Concurrent disease
○ Diet, physical activity, smoking
○ Risk taking behavior
○ SES, education, occupation
● Place
○ Presence of agents or vectors
○ Climate
○ Geology
○ Population density
○ Economic development
○ Nutritional practices
○ Medical practices
● Time
○ Calendar time
○ Time since an event
○ Physiologic cycles
○ Age (time since birth)
○ Seasonality
○ Temporal trends
Case study: COVID-19
● Time
○ When?
○ Trends over time
● Place
○ Where is it affected?
○ Geographical variations
● Person
○ Who is affected?
○ Age, gender, and other characteristics
Epidemics/Pandemics occur when…
● Host , agent, and environmental factors are not in balance due to new agent
● Due to change in existing agent (infectivity, pathogenicity, virulence)
● Due to change in number of susceptible in the population
● Due to environmental changes that affect transmission of the agent of growth of the
agent
●
Example: Food-borne illnesses (FBI) in Canada
●
● We determine associations
● Association does not equal causation
○ Country’s average number of hours watching T.V per day as y-axis
○ Mortality rate from cardiovascular disease as x-axis
What's the denominator?
● Total population vs. population at risk
● The denominator must only include persons who are susceptible to (at risk for) the
outcome
● E.g. lung cancer
Rates
● Help us compare compare health problems among different populations that include two
or more groups who differ by a selected characteristic
● To calculate a rate, we first need to determine the frequency of disease, which includes:
○ The number of cases of the illness or condition
○ The size of the population at risk
○ The period during which we are calculating the rate
Risk
● A proportion or probability
● Cumulative incidence, incidence proportion
● Specific to certain time period
● Assumes patients followed entire time (sometimes problematic due to date of entry,
underlying conditions, loss of follow up, ineligibility)
● Number of patients developing disease over a specific period
---------------------------------------------------------------------------------
Number of subjects followed during that period
Incidence and Prevalence
● Incidence and prevalence measure different aspects of disease occurrence
Prevalence Incidence
Measures of Incidence
● Person-time incidence rate
○ Numerator: # of new cases
○ Denominator: person-time at risk
○ Used when not all people are followed for entire period
○ Observation time from study onset to development of health outcome, to death,
to loss to follow-up, or to study end
○ Must include a unit of time
● Cumulative incidence
○ Numerator: # new cases
○ Denominator: # people at risk at beginning of study period
○ Used when all people are followed for entire period (or it is not possible to
determine person-time at risk)
○ Probability that individuals in the population get the disease during the specified
time period
○ Usually expressed as cases per 1000 population
Prevalence
● Disease burden can be measured in terms of costs, life expectancy, morbidity, quality of
life, or other indicators
● Knowledge of the burden of disease can help determine where investment in health
should be targeted
● Example: monitoring canada's obesity weights in children
● Prevalence proportion or point-prevalence
○ Number of subjects having disease at a particular point in time
-----------------------------------------------------------------------------------
Total number of subjects in the population
● Prevalence period
○ Existing cases at the start of the period plus the new cases that develop over the
study period
-----------------------------------------------------------------------------------------------------------
Total number of subjects in the population
How do we conduct epidemiological studies?
Qualitative Research Studies
● “A holistic and subjective process used to describe and to promote a better
understanding of human experiences and phenomena via the collection of narrative
data, and to develop conceptual models and theories that seek to describe these
experiences and phenomena”
● Study designs to understand needs, perceptions, experiences, and connectedness of
humans, their behaviours:
○ Action research or inquiry
○ Discourse analysis
○ Ecology psychology
○ Ethnographic research
○ Ethnomethodology
○ Ethology
○ Grounded theory
○ Hermeneutics
○ Historical research
○ Phenomenology
Quantitative Research Studies
● “A formal, precise, systematic and objective process in which numerical data are used to
obtain information on a variety of health-related phenomenon of interest or concern”
● Study designs to understand disease burdens, risk and distribution of
determinants/causal factors and their impact on health:
○ Case-control studies
○ Case studies
○ Clinical trials
○ Cohort studies
○ Correlational studies
○ Cross-sectional studies
○ Descriptive studies
○ Experimental studies
○ time-series/time trends studies
Types of Epidemiological (quantitative) studies
-
Experimental studies
Randomization
● Step 3 is the difference between randomized controlled experiments and
non-randomized experiments
● quasi - experiments: non-random approach to divide participants (e.g. where or when
recruited, by sequence of study entry)
● Randomized controlled trials: random approach to divide participants; usually patient and
researcher are blinded to participants’ group status (i.e. double-blinding removes
allocation bias)
Efficacy vs. Effectiveness
● Efficacy
○ Refers to potential impact of treatment under optimal controlled conditions
● Effectiveness
○ Refers to potential impact of treatment under normal, real-world conditions of
routine practice
Example:
● The New England journal of medicine
● Methods: we randomly assigned 3234 non-diabetic persons with elevated fasting and
post load plasma glucose concentrations to placebo, metformin (850 mg twice daily), or
a lifestyle modification program with the goals of at least a 7% weight loss and at least
150 minutes of physical activity per week
● Results: lifestyle changes and treatments with metformin both reduced the incidence of
diabetes in persons at high risk
● Study population: non-diabetic individuals with elevated glucose values (n=3234)
● Randomization: random assignment according ot clinic centre
● Intervention: 1. Lifestyle change; 2. Metformin
● Control : placebo
● Outcome: diabetes
Ethical Issues
● It is unethical to deny a patient access to an effective treatment, but it is also unethical to
adopt a new treatment without conducting rigorous testing to prove efficacy
● It is also unethical to continue a trial if the treatment is found to be obviously effective or
obviously dangerous
● Most epidemiological studies are observational, little potential for harm
● Several critical checks to ensure the potential is negligible, for example:
○ Study must be approved by an institutional research ethics board
○ Participants must be informed about the study purpose, risks and benefits, and
must freely consent to participate
Observational studies: Cohort Studies
● A cohort is a sample of people who share a defining characteristics and can be followed
over time (e.g. birth cohorts share the same year of birth)
● Example
○ Framingham heart study: investigates risk factors for cardiovascular disease
(CVD)
○ In 1948, began following 5,209 adults who did not have CVD
○ Every 2 years, collected data on diet, exercise, medication use etc.
○ Measured new CVD cases
○ Determined effect measures for levels of exercise, cigarette smoking, blood
pressure, and blood cholesterol
Measure of Disease- Relative Risk
● Relative risk: compares risk of health outcome among two groups
● Typically defined by exposure to (primary group) and lack of exposure to (comparator)
suspected causative factor
● Risk ratio = 1.0, identical risk
● Risk ratio > 1.0, increased risk in exposed
● Risk ratio < 1.0, decreased risk in exposed
Case-control studies
● Method: controls are matched with cases for several characteristics so that the two
groups are as similar as possible, except for exposure.
● Starts with disease status
Example
● Lung cancer and smoking
● Important epidemiological study
● Doll and Hill’s study began in 1950
● Identified lung cancer patients in 20 london hospitals and identified comparator group of
patients without lung cancer
● Cases and controls matched by sex, age, hospital
● Surveyed each group about smoking habits (exposure)
● Cases comprised of greater proportion of smokers, and of heavy smokers
Measures disease -Odds ratio
● Exposure-odds ratio for data on cases and controls is the ratio of the odds in favor of
exposure among the cases to the odds in favor of exposure among non-cases
● Reduces to…
● Determines the odds of a disease given the exposure to the risk factor
Descriptive studies
● Unlike analytic and experimental studies, do not aim to test hypotheses
● Focus on ecological units (e.g. subgroups, whole population at different time points)
● Survey-based data collection on risk factors related to disease occurrence
● Generates overall, summary measures (e.g. counts, prevalence)
● Example: cross-sectional study
Cross-sectional studies
● Examines relationship between diseases and risk factors in a defined population
at one time point
● Presence of disease and risk factors determined in each study participant at a given time
point
● Relationship between risk factor and disease allows estimation of:
○ Prevalence of the disease in different subgroups
○ presence/absence of risk factors in individuals with and without the disease
● The time order of cause and effect (temporality) cannot be determined
Challenges with Epidemiological Studies/Science
● Misleading conclusions
○ Chance, random error
○ Bias, systematic error
○ Confounding
Random Error
● There is a natural variability to all uncertain outcomes
● Consider average height in samples of men who are identical in every measurable way
● Average does not change, spread does
● Cannot reduce random error
Systematic Error
● Error in the conception, design or reporting of a study that leads to results or conclusions
that are systematically (as opposed to randomly) different from truth
● Selection bias and recall bias are common forms
Selection bias
● How individuals are selected in the study can produce erroneous estimated associations
or effects on an exposure on an outcome
○ For example, estimated effect of cigarette smoking on heart disease biased if
participants are volunteers and the decision to volunteer is affected by smoking
status or by having a family history of heart disease
● Sampling frame different from target population
● Sampling procedure does not mirror sampling frame
● Solution: rigorous sample selection and recruitment procedures
Recall bias (more relevant for case-control studies)
● Systematic error due to differences in accuracy or completeness of recall to memory of
past events or experiences
● For example, women who have had a baby with malformation will remember better any
events during pregnancy than mothers of infants with no malformations
● Tend to overestimate association between exposure and outcome
● Can reduce through cross-verification of participant responses with medical records
Confounder
● Must be associated with both the risk factor of interest and the outcome
● Must be distributed unequally among the groups being compared
● Cannot be an intermediary step in the causal pathways from the exposure of interest to
the outcome of interest.
● Usually introduced by the investigator or participants
● Solution: controlled for in the analysis through stratification and multivariate regression
methods
● Study on the association between birth order and the risk of down syndrome
● Increasing prevalence of down syndrome with increasing birth order
● Order in which children are born is linked to a woman's age at the time of her child's birth
● Correlation between maternal age and child having down syndrome much stronger
● Relationship between birth order and prevalence of down syndrome is confounded by
age
Challenges with Epidemiological Studies/Science
● Example of false data reporting
● Challenges in pharmaceutical research
● Paid off SickKids hospitals top pediatrician understated the risks of a powerful
antipsychotic used to treat kids with behavioural problem
● Article concluded no correlation between long term use of Risperdal and an increased
risk of growth of breasts in boys
Lecture 4
Public health in the context of infectious disease
Significant public health achievements
● Water purification
● Effective sewage disposal
● Milk pasteurization
● Immunization
● Improved nutrition and personal hygiene
● Chemotherapy
● Antibiotics
What are some contributing factors to global spread of infectious diseases?
● Surveillance: “systematic collection, analysis and timely dissemination of information on
population health to those who need to know, so that action can be taken”
● Surveillance provides information of health and disease and guide planning and
interventions
○ Prevention and control efforts
○ Planning health services
○ Evaluating their (planning) impact
Data sources for Health surveillance
● Vital statistics
○ Births and deaths
● Environmental data
○ Air and water quality
● Health services indicators
○ Hospitalizations, discharge, same day surgery, screening, diagnoses, etc.
● Census data
○ Population data (i.e. income, language, and ethnic group)
Types of Surveillance
● Passive surveillance
○ Reporting mandated or requested from laboratories, care providers, and others in
the community (ongoing)
■ Most common approach to surveillance
■ Less expensive, less complete than other approaches
● Ex: a doctor’s office reports 2 cases of measles
● A nursing home reports an unusual number of older patients with
unexplained rashes
● Monitoring cigarette sales; goes down as years pass
● Active surveillance
○ Active case finding and record review by public health authorities
■ Often initiated as a component of outbreak investigations or when there is
an indication that something unusual is occurring
■ Resource intensive
■ Ex. youth risk behavior surveillance surveys
■ Ex. monitoring covid-19 cases
● Sentinel surveillance
○ Repeated testing or monitoring of groups of people or animals, or environmental
samples
■ Resource intensive
■ Ex. emerging infectious diseases (e.g., west nile virus) and
non-reportable diseases of public health importance (e.g., influenza)
■ emerging/re-emerging infectious diseases wit
● Syndromic surveillance
○ Detect cases before a clinical diagnosis is made, based on behaviours or
symptoms that can be tracked through a variety of data sources
■ Attempt to enhance timeliness and completeness of surveillance for
diseases where cases may not present for medical care and/or receive
laboratory testing
■ Ex. monitoring school or work absenteeism, purchase of over the counter
medications, calls to Telehealth, hospital admission records, google
searches
How do we detect and report outbreaks?
Notifiable diseases
● Globally: obligation under international health regulations to report to the WHO any even
that may constitute a public health emergency of international concern
● In Canada: each province and territory has own legal requirements for reporting certain
infectious and noninfectious diseases considered important for public health monitoring
○ Reporting is mandated by legislation
● Nationally, PHAC collects information from jurisdictions on diseases considered
important for national surveillance
○ Reporting is voluntary, via agreements with provinces and territories
● Provincially: health protection and promotion act requires that each public health unit
collect information about people with reportable diseases in their jurisdiction and report it
to the ministry of health and long term care
○ Integrated public health information system (iPHIS)- database used by all public
health units to report cases
How does surveillance inform decision making?
● An integrated early warning system to transform diverse big data into actionable insights
that help mobilize precise, efficient, timely and coordinated responses across sectors
How could we have prevented SARS?
● Challenge during SARS: Timing! Since the, digital disease detection has emerged as
important tool for outbreak detection
Digital Disease Detection
● The use of media sources and other digital technologies to detect disease outbreaks and
track their spread
Traditional indicator-based surveillance systems
Henle-Koch’s Postulates
● Organism must be present in every case of the disease
● Organism must be able to isolated and grown in pure culture
● Organism must cause specific disease when inoculated into susceptible individual
● Organism must then be removed from such individual and identified
Classification of infectious agents
● Micro-parasites: bacteria
○ Fatty membrane contains DNA and cellular machinery
○ Obtain energy from sugars, proteins, fats
○ Live and multiply outside host
○ Examples: mycobacterium tuberculosis (TB), salmonella typhi (typhoid), vibrio
cholerae
● Bacilli
○ Escherichia coli (intestinal infection, vibrio cholerae (cholera)
● Cocci
○ Streptococci (pharyngitis), staphylococci (skin infections)
● Spirochete
○ Treponema pallidum bacterium (syphilis), borrelia burgdorferi (lyme disease)
● Viruses
○ Smallest infectious disease agent
○ Thin protein coating around genetic material
○ Requires energy from host cells
○ Cannot replicate outside host cell
○ Examples: human immunodeficiency virus, hepatitis C virus
● Parasites
○ Protozoa, helminths, or arthropod
○ Defined nucleus
○ Single or multi celled
○ May or may not need host to replicate
○ Examples: plasmodium falciparum (malaria), lice (head lice)
6 modes of transmission
● Contact
○ Direct physical contact between infected individual and susceptible host (body
surface to body surface)
○ Examples: chlamydia, influenza, infectious mononucleosis
○ Precaution: use condoms, hand hygiene, masks
● Indirect
○ Infectious agent is deposited on surface (fomite) and survives to be transmitted to
susceptible host who touched surface
○ Example: rhinovirus, norwalk, respiratory syncytial virus
○ Precaution: sterilizing instruments, disinfect surfaces and toys, masks
● Dropet
○ Contact
○ By coughing and sneezing large droplets can be projected up to 1 meter
○ Example: meningococcus, respiratory viruses
○ Precaution: surgical mask, cover mouth physical distance
● Airborne
○ Non-contact
○ Transmitted by aerosols (suspended solid particles or liquid droplets) that contain
the organism
○ Example: measles, chickenpox
○ Precaution: masks, use negative pressure rooms
● Vehicle
○ Non-contact
○ Single contaminated source spreads infection (common source or point source)
○ Example: expired restaurant food, listeriosis in 2008
○ Precaution: follow safety standards
● Vector-borne
○ Non-contact
○ Transmitted by animal or insect vectors
○ Example: mosquitos (malaria), ticks (lyme disease)
○ Precaution: protective barriers, window screens, bed nets, insect spray
Characteristics of infectious disease
Crisis Questions
● How many people were harmed or injured?
● Are those who were harmed getting help?
● How are people who were harmed getting help?
● Who is in charge?
● What are you advising people to do>
● Who else is involved in the response?
● Why did this happen?
● When did your response to this begin?
● What was the cause?
How do we do risk communication?
● Best practices in public health risk and crisis communication:
○ Accept and involve stakeholders as legitimate partners
○ Listen to people
○ Be truthful, honest, frank, and open
○ Coordinate, collaborate, and partner with other credible sources
○ Meet the needs of the media
○ Communicate clearly and with compassion
○ Plan thoroughly and carefully
Case Study: West Nile Virus in NYC 1999
● NYC risk communication effort related to the WNV epidemic was far-reaching, resource
intensive, competently handled, and effective
● But there were issues:
○ Little effort was made to collect, analyze, and evaluate empirical information
○ Full range of communication channels not used
○ Official spokespersons were not informed about stakeholder perceptions or about
expected levels of concern, fear, hostility, or outrage
○ Public concern over the city’s decision to use pesticides
○ Lack of attention to the unequal weights given to negative and positive
information in high- concern situations
○ Trust issues and lots of mental noise
Risk communication - in an Infodemic
● Promoting fake products and services (e.g. fake COVID-19 tests and vaccines)
● Promoting a false sense of security (e.g. misleading information about treatments)
● Promoting suspicion of the official guidelines and sources
Quiz 1
● The provincial and territorial governments are responsible for funding provision to:
○ None of the above
○ Not first nations, inuit, metis communities on reserve
○ Not refugee claimants
○ Not individuals in federal corrections
● The Bell-Curve Shift posits that shifting the whole population into a lower risk category
benefits more individuals than shifting high-risk individuals into a lower risk category
○ True
● Which of the following is NOT characteristic of a public health approach?
○ Influence and regulate social, economic, and health policies
○ Diagnoses and treatments limited within health care settings
○ Disease prevention and health promotion
○ Population-wide interventions
● A ___ level of prevention involves actions and measures to eradicate, eliminate, and/or
minimize the pact of disease
○ Primordial
○ Primary
○ Secondary
○ Tertiary
○ Quaternary
●
● As the concept of health evolved from prehistoric times to current times, which
population was the first to implement a prototype of a health maintenance organization?
○ Roman civilizations in Ancient Rome
● ____ refers to an increase, often sudden, in the number of cases of a disease above
what is usually expected in that population in a given region
○ Epidemic , outbreak
● A decline occurred in mortality and morbidity rates in the Canadian population after The
Great Depression due to limited participation in risk behaviours such as drinking and
smoking
○ True
● The critical determinants of health, described by the first evidence-informed report by a
developed nation challenged the mechanistic medical model of health, which include:
○ Human biology, environment, lifestyle, and healthcare organization
● What are the three critical values and principles for delivering public health to residents
in Canada?
○ Equity, social justice, and sustainable development
● Since the onset of the pandemic, the daily new COVID-19 cases across health regions in
Ontario demonstrate that:
○ The trend in new cases appears to be inconsistent across the province with
varying volume of cases over months
Quiz 2
● The total number of cases of a disease existing in a defined population at a specific point
in time (i.e. given year) is called:
○ Point prevalence
● A type of bias that can be corrected through rigorous recruitment procedures
○ Selection bias
● In the province of Ontario, Local Health Integration Networks do not oversee which of the
following?
○ Ontario Health Insurance Program
● A confounder in a research study:
○ Must be associated with both the risk factor of interest and the outcome
● During the SARS epidemic, which of the following exposure settings were linked to the
highest proportion of infections?
○ Healthcare
● Descriptive epidemiology is useful for all of the following purposes except:
○ Testing hypotheses
● Women who have had a baby with a congenital malformation will remember better any
events during pregnancy than mothers of infants with no malformations. This is an
example of:
○ Recall bias
● How does the incubation period differ from the latency period when referring to the
natural history of disease?
○ The incubation period is the time from exposure to pathological changes before
the onset of overt clinical symptoms
● Which of the following is an example of an analytic study design?
○ Case-control study
● What are some challenges with conducting epidemiological studies?
○ Random error
○ Confounding
○ Systematic error
○ All of the above
Lecture 6
Chronic diseases in the context of public health
Mental Health in Canada
● “The capacity of each and all of us to feel, think, and act in ways that enhance out ability
to enjoy life and deal with the challenges we face, and a positive sense of emotional and
spiritual well-being that respects the importance of culture, equity, social justice,
interconnections and personal dignity”
● Allostatic load: wear and tear on the body (eustress, distress)
● Coping and coping mechanisms: who is responsible to take action?
Key facts
● 6.7 million people in Canada are living with a mental health condition or illness today
● By age 40, about 50% of the population will have or have had a mental illness
● Suicide is one of the leading causes of death in both men and women from adolescence
to middle age
Mental illness in Canada
● “Alterations in thinking, mood or behaviour- or some combination thereof- associated
with significant distress and impaired functioning”
● Chemical imbalance theory-
● Three general theories related to the aetiology of mental illness and disorders:
○ supernatural , (attributed to possession and/or punishment by evil or demonic
spirits, displeasure of gods or deities, etc)
○ Psychogenic, (traumatic or stressful experiences, distorted perception, treatment
via psychotherapy and psychoanalysis)
○ Somatogenic (disturbances in physical functioning resulting in either illness,
genetic inheritance, brain damage or chemical or force of nature imbalances)
● Burden of mental illness in canada
● Who is at risk?
○ Those who are homeless, don't have access to health care, no income
● How do we provide access to mental health services?
● What are the challenges in our system?
● An estimated 1 in 5 canadians experience a mental health problem or disorder in any
given year
● 7.5 million canadians live with a mental health problem or illness twice the number of
people with heart disease or type 2 diabetes
Mental Health in Canada
● 1 in 5 canadians experiences a mental health or addiction problem
● 2.3 million adults with mood disorders in canada, ⅔ of them were females
● 6.7 million adults who reported that their perceived life stress was “quite a lot”. More than
half were females
● Only one in three people who experience a mental health problem or illness report that
they have sought and received services and treatment
● Cost to the economy of well in excess of $50 billion
Is Bell let’s talk about the solution?
● “You want to have a real talk about mental health, Bell Canada? Then, with all due
respect for the genuine good of the “let's talk” day, please shut up. Turn down the
volume on your logo and focus in on using the substantial financial resources and
massive communications infrastructure to raise up voices that are usually silenced”
● “(but) the campaign is just the tip of the iceberg...using the hashtag or posting a picture
online one day a year does not dive into the underlying issues our society is facing”
Priority Strategic directions from a population health perspective- by the CMHC
● “Promote mental health across the lifespan in homes, schools, and workplaces, and
prevent mental illness and suicide wherever possible
● Foster recovery and well-being for people of all ages living with mental health problems
and illnesses, and uphold their rights
● Provide access to the right combination of services, treatments, and supports, when and
where people need them
● Reduce disparities in risk factors and access to mental health services, and strengthen
the response to the needs of diverse communities and Northerners.
● Work with first nations, inuit, and metis to address their mental health needs,
acknowledging their distinct circumstances, rights and cultures
● Mobilize leadership, improve knowledge, and foster collaboration at all levels”
Genetic Diseases
Congenital anomalies
● Structural or functional anomalies (for example, metabolic disorders) that occur during
intrauterine life
● Can develop at conception (e.g. down syndrome, achondroplasia), embryonic period (0
to 7 gestation)(e.g.spina bifida), or early fetal period (8 to 16 gestation)
● Significant source of disability, health system costs)
● Between 1998 and 2009, the national congenital anomalies prevalence rate decreased
from 451 to 385 per 10,000 total births
● Approximately 1 in 25 canadian babies is diagnosed with 1 or more congenital
anomalies every year
● 2nd leading cause of infant death (23%)
Are chromosomal abnormalities inherited?
● Most chromosomal disorders are not passed from one generation to the next
● Examples: down syndrome, turner syndrome
● Such chromosomal abnormalities caused by
○ Changed in the number of chromosomes
○ Changes in the structure of chromosomes
Environmental Factors
Teratogens:
● Infectious agents (e.g., rubella, syphilis, toxoplasma)
● Physical agents (e.g., ionizing agents, hyperthermia)
● Maternal health factors (e.g. diabetes)
● Environmental chemicals (e.g. mercury, herbicides)
● Drugs (e.g. Prescription, recreational)
● Low birth weight babies face risk of vertebral palsy, mental health disorders
● Birth defects associated with prenatal exposure to alcohol can occur in the first three to
eight weeks of pregnancy
The burden of Chronic diseases
● 3 of 5 people 20+ years hace a chronic disease
● 4 of 5 people 20+ years are at risk for chronic disease
● In 2012, 219,500 deaths due to chronic disease; 27% such death premature (i.e. <70
years old)
● Chronic disease in Ontario accounts for 79% deaths
Chronic disease
● Complex causality, with multiple factors leading to their onset
● A long development period, for which there may be no symptoms
● A prolonged course of illness, perhaps leading to other health complications
● Associated functional impairment or disability
Top 4 Chronic disease worldwide
● Cardiovascular disease
● Diabetes
● Cancer
● Chronic respiratory
Cardiovascular disease
● Disease burden
○ Accounts for 22% of deaths in females, 26% in males
○ $21 B in mortality costs, physician/hospital services, lost productivity
○ 80% of canadians, have at least one risk factor for cardiovascular disease
● Physiological mechanisms
○ Atherosclerosis contributes to CVD
○ Plaque narrows arteries, restricts blood flow, forms clots
○ Causes heart attacks and strokes
○ Risk factors: high cholesterol, diabetes, smoking excess alcohol use, etc
Diabetes
● Disease burden
○ Contribute to 41,500 candian deaths each year
○ Prevalence will reach 3.5B by 2018/19
○ $11.78 for treatment in 2010
● Physiological mechanisms
○ Body either cannot produce insulin or properly use the insulin it produces
○ Insulin hormone controls blood sugar by causing cells to absorb sugar as energy
or as fat
○ High blood sugar damages organs, blood vessels, nerves
● Type 1 diabetes
○ Immune system attacks and kills the beta cells of the pancreas that creates
insulin
○ Sugat builds up in the blood instead of being used as energy
○ Generally develops in childhood or adolescence, but can develop in adulthood
○ Treatment includes insulin, meal planning
● Type 2 diabetes
○ Accounts for nearly 90% of diabetes cases
○ Body cannot effectively use insulin or does not create sufficient insulin
○ Generally develops in adulthood, but can affect children
○ Treatment can include drugs, insulin, meal planning, physical activity
Challenge: undiagnosed diabetes
● “Canadian study (2015) found that 1.13% of the canadian adult population (20+) had
undiagnosed diabetes based on fasting plasma glucose levels
○ The hemoglobin A1c test demonstrates average level of blood sugar
○ Canadian guidelines diagnosis criteria: hemoglobin A1C level of greater or equal
to 6.5%
Cancer
● Disease burden
○ 2 in 5 canadians will develop cancer in their lifetime (40% of women and 45% of
men)
○ 206, 200 new cases of cancer and 80,000 deaths from cancer in canada in 2017
○ Half of all new cases will be lung, colorectal, breast, and prostate cancer
● Physiological mechanisms
○ Body either cannot produce insulin or properly use the insulin it produces
○ Insulin hormone controls blood sugar by causing cells to absorb sugar as energy
or as fat
○ High blood sugar damages organs
Chronic disease research
● Randomized controlled trials
○ Ethical concerns
● Observational epidemiologic studies
○ on y observe natural phenomena
● Animal model studies
○ Controlled conditions; study effects across lifespan; biological processes differ;
may not be susceptible
● Laboratory culture studies
○ Oversimplified conditions
The pipeline of evidence informing practice
●
Common risk behaviors as causes for chronic diseases
● Unhealthy diets (ie., processed foods, concentrated fats, inadequate fruit and vegetable
consumption)
● Physically inactive (increase sedentary behaviors, cost 6.8B)
● Tobacco (responsible for 85% if lung cancer; 7.2 billion direct and indirect costs in
Ontario)
● Alcohol use (high consumption, responsible for 3.3M deaths worldwide)
Social determinants of health as causes for chronic diseases
Take Action
● Society
○ Public policy and governmental interventions should be aimed at modifying
policies and creating environment to promote healthy behaviours in individuals
○ Population based tobacco control strategies require few sources to
■ To increase taxes on tobacco products
■ Ban cigarette advertising
■ Restrict spaces to smoke
● Community
○ Collective engagement in ensuring access exercise facilities, team sports,
healthy food, support groups to quit smoking and tackle obesity
● Individual
○ Empowerment of individuals to help manage conditions through lifestyle changes
and adherence to treatment regimens
Lecture 7
The determinants of health and health behaviour
Epidemiology
● Focuses principally on variations between people that are systematic, meaning that
identifiable groups of people experience different levels of health”
● The interacting triad of causal factors
○
○ Agent, environment, host
Clinical course of a disease: pre- and post-disease stages
Risk factors
● Suspected causes of disease at the individual level
● Characteristics of the person, their behaviour or environment
● ‘Risk’ or probabilistic language fitting since very few exposures inevitably cause disease
Determinants of health (Dahlgren & whitehead)
● General term describing proximal and distal factors that impact health -micro (genetics,
heredity, biology), meso (family, neighbourhood, community), and macro (national and
international conditions)
Social Determinants of health
● Income and social status
● Social support networks
● Education and literacy
● employment/working conditions
● Social environments
● Physical environments
● Personal health practices and coping skills
● Healthy child development
● Biology and genetic endowment
● Health services
● Gender
● Culture
The Lalonde Report, 1974
Brunner and Marmot’s model
● Intermediary factors:
○ Material factors
■ housing , work conditions
○ Psychosocial factors
■ Stressful living conditions and life events, lack of social supports
○ Behavioural and/or biological factors
■ smoking , eating habits
Upstream vs. Downstream determinants
● “Refer to underlying characteristics of society that ultimately shape the health of
individuals and communities”
● Upstream factors
○ Broader social, economic, and political forces that influence chain of intermediate
processes and lead to specific diseases among individuals, whereas downstream
factors, include micro level determinants
● Non specific factors
○ Poverty reduction policies, education policies, food insecurity, climate change
policies or policies that focus on creating supportive environments
● Post pic
Health inequalities
● “Systematic differences in health status between groups of people, including both those
that arise naturally,, and those whose origins lie in social disadvantage… may result from
biological differences or from personal choices, social conditions..”
Health Inequities
● Systemic
● Avoidable
● Unfair and unjust
Social production of disease
● Do we not always find the diseases of the populace traceable to defects in society? - Dr.
Rudolf Virchow (father of social medicine)
Is COVID-19 a social and economic production?
-
Social conditions and health status
● “The result [of the social situation] is the same as if 20 or 30,000 of these people were
annually taken out of their wretched dwelling and put to death… and we know the
economic, financial, and political forces responsible for this” - Edwin Chadwick
Capitalist production and working class
● Among the british working class, there is an incompatibility between the capitalist
economic system and the health and working conditions of working people
Production of inequalities
● “A girl born in Sweden will live 43 years longer than a girl born in Sierra leone”
● “In Glasgow, an unskilled, working class person will have a lifespan 28 years shoert than
a businessman in the top income bracket in scotland - Vincent Navarro
Socio economic status across the lifespan
● As a general rule:
○ The wealthier the population the better their health status, the poorer the
population the worst their health outcomes. Measured using three components
○ Income increases the opportunities for nad education, and occupation increases
one's income, and an education increases one's job opportunities and therefore
income
●
Case study 2: Health of immigrant populations
● “Overall, immigrants appear to be healthier than the Canadian-born population, by virtue
of being capable, both physically and mentally, of successfully moving themselves, and
often their families, from one country to another. However, over time, this healthy
immigrant effect is lost”
● Why is this the case?
○ Healthy migrant effect?
● “The health of migrants is a product of environmental, economic, genetic, and
socio-cultural factors related to when people migrated to Canada, where and how they
lived in their original home country, and how and why they migrated”
● Why is this the case?
○ Premigration, migration, and post migration resettlement, as well as social
determinants of health
How can public health behaviour change?
Health behaviours
● Illness behaviour
○ Refers to the actions people take in response to their illness, including whether or
not they seek healthcare and whether or not they follow the doctor’s
recommendations
● Smoking and drinking
● Physical activity
● Diet
● Sleep
● Safe sex
Models of health behaviour change
Trans-theoretical change
-
Lecture 8
Health Promotion & Disease Prevention
Ethological phase
Health Promotion
● “Aims to help people increase control over and improve their health”
● Who?
○ Individual, family, community, sector/system, society
● What?
○ Income, social status, education, healthy child development, work and
environment, social support, personal skills, biology, health services
● How?
○ Community action, public policy, supportive environment, personal skills, health
services
● Evidence based decisions
○ Research, experience, evaluation
○ Values and assumptions:
■ Evidence forms the bases of agreements between program and policy
decision makes, health promoters analyze all possibilities and act within
their jurisdiction, there is a need for overall coordination of activity, society
as whole must take care of all its members, interaction between people
and their physical and social surroundings affects health and health
behaviors, social justice, equity, mutual respect and caring are necessary
for health, health care, health protection and disease prevention
complement health promotion
Key Health Promotion Values
● Equity and social justice
● Holistic definition of health (well-being)
● Enhances health, not just preventing disease
● Encompass full range of determinants of health
● Recognizes role of environments (settings) in shaping human behaviour
● Empowerment
● Meaningful social participation (not just tokenistic)
Models of Health Promotion
● Tannahill 1985
○ Health protection
■ Includes public policies that address fair access to housing, employment,
education, and health care
○ Health promotion
■ “Sustainable fostering of positive health and prevention of ill health
through policies, strategies, and activities in the overlapping action areas
of:
● social ,economic, physical, environmental and cultural factors;
● Equity and diversity
● Education and learning
● Services, amenities, and products
● Community led and community based activity
● Caplan and Holland 1990
○ What is it?
■ More complex and theoretically driven
■ Attempts to unpick what determines health and ill health and therefore
what activities can be used to address health issues
■ One axis refers to a theory of knowledge and how knowledge is
generated in relation to health
■ The other axis refers to how society is constructed and how this impacts
on health
○ An objective perspective
■ One that is not influenced by emotions, opinions, or personal feelings
-based on quantifiable and measurable facts
○ A subjective perspective
■ Open to greater interpretation based on personal feeling, emotion,
aesthetics
○ Radical humanist paradigm
■ Concerned with releasing social constraints that limit human potential
○ Humanism
■ An approach in study, philosophy, or practice that focuses on human
values and concerns
○ Radical structuralist
■ Contemporary society is characterized by fundamental conflicts which
generate radical change through political and economic crises
○ Traditional
■ Embedded in behavioural understandings of disease and illness
● Beattie 1991
○ Examines 2 axis
■ Type of approach used top-down (authoritarian) or bottom up (negotiated
or owned by the clients)
■ Size of approach categories 4 types of activities
● Personal counseling: working with dietician on food and physical
individual person plans and goals
● Health persuasion: campaign for eating 5 fruits and vegetables a
day on TV
● Legislative action: laws that subsidize the price of healthy food
stuff
● Community development: communities producing and distributing
food themselves
●
Approaches that act on the SDOH inequalities
● Political economy
○ Assumptions and ideologies that underlie political and state structures and the
effects that these have on populations
○ Focus on power and wealth distribution
● Macrosocial policies
○ Broad social policies that provide the conditions concomitant with the underlying
ideological structures of governance of the state (universal health care, in liveral
democracies, for example, or provisions for daycare in social democracies)
● Intersectionality
○ Understanding that discrimination and disadvantage operate isn distinct easy
across social categories to produce intersections that are more or less salient in
some places and times
● Life course approach
○ Calls for intervention aimed at reducing health inequalities by considering the
multiple dimensions of lives as they are actually lived
The settings approach
● Reduce inequalities
● Equitable distribution of physical and social resources
● Supportive environments
●
● Process:
○ Inputs: “resources that go into a program or intervention- what we invest. They
include financial, personnel, and in-kind resources from any source”
○ Activities: “events undertaken by the program or partners to produce desired
outcomes - what we do. You could include a clear identification of “early”
activities and “later” activities”
○ Outputs: “direct, tangible results of activities- what we get. These early work
products often serve as documentation of progress”
○ Outcomes: “the desired results of the program- what we achieve. Describing
outcomes as short, intermediate, or long term depends on the objective, the
length of the program, and expectations of the program or intervention”
● Outcome:
○ Short term outcomes: immediate effects of the program or intervention activities,
they often focus on the knowledge and attitudes of the intended audience
○ Intermediate outcomes: behavior, normative, and policy changes
○ Long-term outcomes: the desired results of the program and can take years to
accomplish
○ Impacts: the ultimate impacts of the program. They could be achieved in a year
or take 10 or more years to achieve. May not be reflected in the model,
depending on length and scope of the program
Community engaged practice interventions (CEPI) for type 2 diabetes
● Interdisciplinary and evidence based community interventions put into practice
● Scientific professionals, practitioners and community change agents (engaged
stakeholders) have shared circumstances and work together as equal partners in the
development of an action oriented agenda
● Clinical care outcomes and chronic disease management align with community based
public health practice
● Evidence based implementation and diffusion of actionable innovation v, results-based
outcomes are relevant, sustainable and replicable
Lecture 10
Global Public Health
Global health and public health share common features:
● Population based and prevention focused
● Marginalized populations
● Multidisciplinary approaches
● Consider health as a public good and values health infrastructure
● Comprise of several stakeholders
Unique features of global health:
● International health
● Global health
● Global public health
Defining global health, international health, and public health
-
Geographical reach
● Global health
○ Focuses on health issues affected by transnational determinants
○ E.g. climate change, large-scale outbreaks, polio eradication
○ ‘Global’ refers to scope of issue, not simply location
● Public health
○ Focuses on health issues that affect the health of the population of a particular
community or country
Level of Cooperation
● Global health
○ Development and implementation of solutions requires global cooperation
○ High-resource settings do not have monopoly on good ideas, cross-cultural
disease prevention, efficient food production
○ Emphasizes mutuality, pooling knowledge, exchange between high and low
resource settings
● Public health
○ Development and implementation of solutions does not usually require global
cooperation
● International health cooperation projects
○ 36% support to the healths systems
○ 44% maternal and child health
○ 12% non communicable diseases
○ 8% infectious diseases
Individuals or populations
● Global health
○ Embraces both prevention in populations and clinical care of individuals
● Public health
○ Mainly focused on prevention programs for populations
Access to Health
● Global health
○ Health equity among nations and for all people is a major objective
● Public health
○ Health equity within a nation or community is a major objective
Range of disciplines
● Global health
○ Highly interdisciplinary and multidisciplinary within and beyond health sciences
■ E.g. law, economics, history, engineering, biomedical and environmental
sciences, and public policy
● Public health
○ Encourages multidisciplinary approaches, particularly within health sciences and
with social sciences
Global Health 2035: WDR 1993 @20 years
● the world bank's world development report 1993
○ Evidence based health expenditures are an investment not only in health, but in
economic prosperity
○ Additional resources should be spent on cost-effective interventions to address
high-burden diseases
● The lancet commision on investing in health
○ Reexamines the case for investing in health
○ Proposes a health investment framework for low and middle income countries
○ Provides a roadmap to achieving gains in global health through a ‘grand
convergence’
1993- 2013: Extraordinary health & economic progress
-
2015-2035: Three domains of health challenges
● Unfinished agenda
○ High rates of avertable infectious, child, and maternal deaths
● Emerging agenda
○ Demographic change and shift in GBD towards NCDs and injuries
● Cost agenda
○ Impoverishing medical expenses, unproductive cost increases
Global Health 2035: 4 Key Messages
● A grand convergence in health is achievable within our lifetime
● Fiscal policies are a powerful, underused lever for curbing noncommunicable diseases
and injuries
● The returns from investing in health are extremely impressive
● Progressive pathways to universal health coverage are an efficient way to achieve health
and financial protection
Population dynamics model
● S-shaped pattern:
○ Temporary exponential growth rate is followed by plateau
● J-shaped
○ Population growth rate (no. of organisms per generation) increases as the
population gets larger
Determinants of carrying capacity
● Availability of freshwater
● Amount of arable land
● Availability of fuel, resources
● Amount of technological and biological waste
● 1700s, death rates declined remarkably due to :
○ New technologies in agriculture, treatment, and health
○ Greater survival beyond adolescence
○ Increase in population average life expectancy
○ Adoption of health lifestyles
○ Health promotion and public health efforts
Demographic Transition Model
● Helps to explain and make sense of population demographics within a country
● Each stage characterized by relationship between birth and death rates
● Relationship changes as country acquires resources
● Country’s total population growth rate cycles through stages
● Stage 1:
○ Most of the world before the Industrial Revolution; N is stable
● Stage 2
○ Least developed countries modern medicine decrease DR in children; high BR
● Stage 3
○ Developing countries; BR gradually decreases due to improved economics,
women's health, access to contraception; N growth constant
● Stage 4
○ Most developed countries; high SES, working women, 2 child per woman; N
growth slows down
● Stage 5
○ Countries where fertility rate below 2 child per woman; elderly population greater
than reproducing population; N declines
Crowding and Urbanization
● 1950-2019: people living in cities increased from 33% to over 80%
● Conditions threaten to reverse public healths progress
○ Increasing volumes of uncollected waste
○ Concentrated automobile exhaust pollutes air
○ Disruption of traditional lifestyles
● Example: cholera in Dar ES Salaam, Tanzania
○ Example of major informal settlement expansion
○ Along coastline and roads
○ N= 76,000 in 1950 to 3.31 million in 2008
○ 65% live informal areas
○ Study demonstrated cholera incidence associated with
■ Informal housing
■ Population density
■ Income level
Climate Change
● Population growth changing composition of Earth
● Combustion of wood, coal, oil, and gas
● Increased concentration of atmospheric carbon dioxide
● Causing global warming and greenhouse effect
● Impact on public health
● Extreme temperatures, weather events, wildfires
● Degraded outdoor air quality
● Water and food shortage
● Increased insect related infections
Emergency preparedness and response to outbreaks and disasters
● Example: spread of vector-borne diseases
○ Weather patterns can alter:
■ Vectors population size and density
■ Vectors survival rates
■ Relative abundance of disease carrying animals
■ Pathogen reproduction rates
○ Vector borne disease transmission depend on
■ Pathogens adapt and change
■ Availability of vectors, zoonotic hosts
■ Changing ecosystems and land use
■ Human demographics, behaviour, and adaptive capacity
COVID-19 Seroprevalence in Ontario
● Public Health Ontario (PHO) has initiated a COVID-19 Serosurveillance program
● To estimate the proportion of the Ontario population that has been infected by and
developed antibodies against SARS-CoV-2
● Serology testing: a lab test that measures antibodies specific to COVID-19 (f someone
has been previously infected not current infections)
● Findings: from June 5 tp 30, the study found 1.1% of the samples were positive for
COVID-19 antibodies- meaning: 160,000 of 15 million Ontarians could have been
infected in June alone
● Toronto: known- 15,000 cases, but actual rates could be 4X higher
● Therefore “we must all continue our public health measures to prevent the ongoing
spread of COVID-19, and we must keep our vulnerable populations protected”
Natural Events and Disasters
● May be predictable (e.g., hurricanes, forest fires, blizzards) or unpredictable (e.g.,
earthquake)
● Usually occur in predictable geographic regions
● Communities can develop and implement disaster plans such as floods, earthquakes,
fires and highly dangerous infectious diseases
● May include industrial explosions, building and bridge collapses, terrorist events
● Not predictable but potential can be sometimes be identified
● Impact can be minimized through government regulation and community planning
Impact and the role of public health
● Disasters yield health consequences for immediate victims, emergency response
personnel, volunteers, general public
● Public health’s role
● Planning preparedness in advance of the emergency
● Coordinating activities of the responders
● Being knowledgeable about community resources